The ribonucleotide reductase R1 subunits of herpes simplex virus types 1 and 2 protect cells against TNFα- and FasL-induced apoptosis by interacting with caspase-8

Apoptosis

Volumn 16, Issue 3, 2011, Pages 256-271

  Dufour, Florent ^a   Sasseville, A Marie Josée ^a   Chabaud, Stéphane ^a,f   Massie, Bernard ^b,c,d   Siegel, Richard M ^e   Langelier, Yves ^a,b  

^a NOTRE DAME HOSPITAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^d INRS INSTITUT ARMAND FRAPPIER   (Canada)

^e NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^f UNIVERSITÉ LAVAL   (Canada)

Author keywords

Caspase 8; FasL; ICP10; ICP6; Viral inhibitor of apoptosis

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; CASPASE 8; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RIBONUCLEOTIDE REDUCTASE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

APOPTOSIS; ARTICLE; CELL PROTECTION; DIMERIZATION; ENZYME ACTIVATION; ENZYME BINDING; ENZYME SUBUNIT; GENE OVEREXPRESSION; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

APOPTOSIS; CASPASE 8; CELL LINE, TUMOR; CELL SURVIVAL; CYTOPROTECTION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FAS LIGAND PROTEIN; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; GENE DELETION; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; PROTO-ONCOGENE PROTEINS C-AKT; RIBONUCLEOTIDE REDUCTASES; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 2; HUMAN HERPESVIRUS 4; SIMPLEXVIRUS;

EID: 79952194140     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-010-0560-2     Document Type: Article

References (71)

1. GH Wong LA Tartaglia MS Lee DV Goeddel 1992 Antiviral activity of tumor necrosis factor is signaled through the 55-kDa type I TNF receptor [corrected] J Immunol 149 3350 3353 1331233 1:CAS:528:DyaK3sXnvFSnsg%3D%3D
2. M Chawla-Sarkar DJ Lindner YF Liu BR Williams GC Sen RH Silverman EC Borden 2003 Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis Apoptosis 8 237 249 12766484 10.1023/A:1023668705040 1:CAS:528:DC%2BD3sXjsF2nt70%3D (Pubitemid 36749609)
3. T Ishikawa H Yamada A Oyamada F Goshima Y Nishiyama Y Yoshikai 2009 Protective role of Fas-FasL signaling in lethal infection with herpes simplex virus type 2 in mice J Virol 83 11777 11783 19740996 10.1128/JVI.01006-09 1:CAS:528:DC%2BC3cXksFKqtLw%3D
4. JR Lokensgard S Hu W Sheng M van Oijen D Cox MC Cheeran PK Peterson 2001 Robust expression of TNF-alpha, IL-1beta, RANTES, and IP-10 by human microglial cells during nonproductive infection with herpes simplex virus J Neurovirol 7 208 219 11517395 10.1080/13550280152403254 1:CAS:528:DC%2BD3MXlvFaisLg%3D (Pubitemid 32685255)
5. SH Chen JE Oakes RN Lausch 1994 Synergistic anti-herpes effect of TNF-alpha and IFN-gamma in human corneal epithelial cells compared with that in corneal fibroblasts Antiviral Res 25 201 213 7710269 10.1016/0166-3542(94)90004- 3 1:CAS:528:DyaK2MXitlWmurk%3D (Pubitemid 24371525)
6. Y Sergerie S Rivest G Boivin 2007 Tumor necrosis factor-alpha and interleukin-1 beta play a critical role in the resistance against lethal herpes simplex virus encephalitis J Infect Dis 196 853 860 17703415 10.1086/520094 1:CAS:528:DC%2BD2sXhtFanu7rL (Pubitemid 47378934)
7. Y Langelier S Bergeron S Chabaud J Lippens C Guilbault AM Sasseville S Denis DD Mosser B Massie 2002 The R1 subunit of herpes simplex virus ribonucleotide reductase protects cells against apoptosis at, or upstream of, caspase-8 activation J Gen Virol 83 2779 2789 12388814 1:CAS:528: DC%2BD38XosF2jsbg%3D (Pubitemid 35276978)
8. L Liang B Roizman 2006 Herpes simplex virus 1 precludes replenishment of the short-lived receptor of tumor necrosis factor alpha by virion host shutoff-dependent degradation of its mRNA J Virol 80 7756 7759 16840355 10.1128/JVI.00587-06 1:CAS:528:DC%2BD28XnsVWgurY%3D (Pubitemid 44092595)
9. NS Wilson V Dixit A Ashkenazi 2009 Death receptor signal transducers: nodes of coordination in immune signaling networks Nat Immunol 10 348 355 19295631 10.1038/ni.1714 1:CAS:528:DC%2BD1MXjtlymsLw%3D
10. S Kreuz D Siegmund P Scheurich H Wajant 2001 NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling Mol Cell Biol 21 3964 3973 11359904 10.1128/MCB.21.12.3964-3973.2001 1:CAS:528:DC%2BD3MXktFWgt7k%3D (Pubitemid 32476458)
11. A Krueger I Schmitz S Baumann PH Krammer S Kirchhoff 2001 Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex J Biol Chem 276 20633 20640 11279218 10.1074/jbc.M101780200 1:CAS:528:DC%2BD3MXktlKnurc%3D
12. C Bagneris AV Ageichik N Cronin B Wallace M Collins C Boshoff G Waksman T Barrett 2008 Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome Mol Cell 30 620 631 18538660 10.1016/j.molcel.2008.04.029 1:CAS:528:DC%2BD1cXntlWmsLk%3D (Pubitemid 351755065)
13. O Micheau J Tschopp 2003 Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes Cell 114 181 190 12887920 10.1016/S0092-8674(03)00521-X 1:CAS:528:DC%2BD3sXlvFCgu7Y%3D (Pubitemid 36936912)
14. N Harper M Hughes M MacFarlane GM Cohen 2003 Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis J Biol Chem 278 25534 25541 12721308 10.1074/jbc.M303399200 1:CAS:528:DC%2BD3sXlt1Cmuro%3D (Pubitemid 36835305)
15. A Thorburn 2004 Death receptor-induced cell killing Cell Signal 16 139 144 14636884 10.1016/j.cellsig.2003.08.007 1:CAS:528:DC%2BD3sXptVWmtr4%3D (Pubitemid 37431163)
16. H Wajant K Pfizenmaier P Scheurich 2003 Tumor necrosis factor signaling Cell Death Differ 10 45 65 12655295 10.1038/sj.cdd.4401189 1:CAS:528: DC%2BD3sXit12mu7s%3D (Pubitemid 36511832)
17. JR Muppidi J Tschopp RM Siegel 2004 Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction Immunity 21 461 465 15485624 10.1016/j.immuni.2004.10.001 1:CAS:528:DC%2BD2cXpvVygt7g%3D (Pubitemid 39370502)
18. CY Wang MW Mayo RG Korneluk DV Goeddel AS Baldwin Jr 1998 NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation Science 281 1680 1683 9733516 10.1126/science.281.5383.1680 1:CAS:528:DyaK1cXmtVWhurk%3D (Pubitemid 28435585)
19. DJ Goldstein SK Weller 1988 Factor(s) present in herpes simplex virus type 1-infected cells can compensate for the loss of the large subunit of the viral ribonucleotide reductase: characterization of an ICP6 deletion mutant Virology 166 41 51 2842955 10.1016/0042-6822(88)90144-4 1:CAS:528: DyaL1cXlvVCmsrw%3D
20. R Ingemarson H Lankinen 1987 The herpes simplex virus type 1 ribonucleotide reductase is a tight complex of the type alpha 2 beta 2 composed of 40 K and 140 K proteins, of which the latter shows multiple forms due to proteolysis Virology 156 417 422 3027985 10.1016/0042-6822(87)90422-3 1:CAS:528:DyaL2sXhvFWktLw%3D (Pubitemid 17021037)
21. MA Swain DA Galloway 1986 Herpes simplex virus specifies two subunits of ribonucleotide reductase encoded by 3′-coterminal transcripts J Virol 57 802 808 2419588 1:CAS:528:DyaL28Xhs1altLs%3D (Pubitemid 16143959)
22. D Perkins EF Pereira M Gober PJ Yarowsky L Aurelian 2002 The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway J Virol 76 1435 1449 11773417 10.1128/JVI.76.3.1435-1449.2002 1:CAS:528: DC%2BD38XnvFCqtg%3D%3D (Pubitemid 34066444)
23. J Conner 1999 The unique N terminus of herpes simplex virus type 1 ribonucleotide reductase large subunit is phosphorylated by casein kinase 2, which may have a homologue in Escherichia coli J Gen Virol 80 Pt 6 1471 1476 10374965 1:CAS:528:DyaK1MXjs1Omtbc%3D (Pubitemid 29261478)
24. Y Langelier L Champoux M Hamel C Guilbault N Lamarche P Gaudreau B Massie 1998 The R1 subunit of herpes simplex virus ribonucleotide reductase is a good substrate for host cell protein kinases but is not itself a protein kinase J Biol Chem 273 1435 1443 9430680 10.1074/jbc.273.3.1435 1:CAS:528: DyaK1cXktFGisw%3D%3D (Pubitemid 28133664)
25. MD Gober SQ Wales L Aurelian 2005 Herpes simplex virus type 2 encodes a heat shock protein homologue with apoptosis regulatory functions Front Biosci 10 2788 2803 15970534 10.2741/1736 1:CAS:528:DC%2BD2MXntFGisb4%3D (Pubitemid 40905275)
26. S Chabaud H Lambert AM Sasseville H Lavoie C Guilbault B Massie J Landry Y Langelier 2003 The R1 subunit of herpes simplex virus ribonucleotide reductase has chaperone-like activity similar to Hsp27 FEBS Lett 545 213 218 12804778 10.1016/S0014-5793(03)00547-7 1:CAS:528:DC%2BD3sXksVOktro%3D (Pubitemid 36694704)
27. D Walsh I Mohr 2006 Assembly of an active translation initiation factor complex by a viral protein Genes Dev 20 461 472 16481474 10.1101/gad.1375006 1:CAS:528:DC%2BD28Xhslaqu70%3D (Pubitemid 43244400)
28. S Chabaud AM Sasseville SM Elahi A Caron F Dufour B Massie Y Langelier 2007 The ribonucleotide reductase domain of the R1 subunit of herpes simplex virus type 2 ribonucleotide reductase is essential for R1 antiapoptotic function J Gen Virol 88 384 394 17251554 10.1099/vir.0.82383-0 1:CAS:528: DC%2BD2sXhsFakur8%3D (Pubitemid 46210875)
29. CB Whitehurst S Ning GL Bentz F Dufour E Gershburg J Shackelford Y Langelier JS Pagano 2009 The EBV deubiquitinating enzyme, BPLF1, reduces EBV ribonucleotide reductase activity J Virol 83 4345 4353 19244336 10.1128/JVI.02195-08 1:CAS:528:DC%2BD1MXlt1Kqu74%3D
30. RM Siegel DA Martin L Zheng SY Ng J Bertin J Cohen MJ Lenardo 1998 Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis J Cell Biol 141 1243 1253 9606215 10.1083/jcb.141.5.1243 1:CAS:528:DyaK1cXjs12ntbw%3D (Pubitemid 28265617)
31. M Laramee C Chabot M Cloutier R Stenne M Holgado-Madruga AJ Wong I Royal 2007 The scaffolding adapter Gab1 mediates vascular endothelial growth factor signaling and is required for endothelial cell migration and capillary formation J Biol Chem 282 7758 7769 17178724 10.1074/jbc.M611327200 1:CAS:528: DC%2BD2sXis1KgsL4%3D (Pubitemid 47093597)
32. N Holler A Tardivel M Kovacsovics-Bankowski S Hertig O Gaide F Martinon A Tinel D Deperthes S Calderara T Schulthess J Engel P Schneider J Tschopp 2003 Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex Mol Cell Biol 23 1428 1440 12556501 10.1128/MCB.23.4.1428-1440.2003 1:CAS:528:DC%2BD3sXhtF2js7k%3D (Pubitemid 36177050)
33. C Scaffidi JP Medema PH Krammer ME Peter 1997 FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b J Biol Chem 272 26953 26958 9341131 10.1074/jbc.272.43.26953 1:CAS:528: DyaK2sXmvFyrsLw%3D (Pubitemid 27452647)
34. Z Nie BN Phenix JJ Lum A Alam DH Lynch B Beckett PH Krammer RP Sekaly AD Badley 2002 HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation Cell Death Differ 9 1172 1184 12404116 10.1038/sj.cdd.4401094 1:CAS:528:DC%2BD38XotFOrsb8%3D (Pubitemid 35331764)
35. JP Medema C Scaffidi PH Krammer ME Peter 1998 Bcl-xL acts downstream of caspase-8 activation by the CD95 death-inducing signaling complex J Biol Chem 273 3388 3393 9452459 10.1074/jbc.273.6.3388 1:CAS:528:DyaK1cXhtVynur8%3D (Pubitemid 28109756)
36. B Peant JS Diallo F Dufour C Le Page N Delvoye F Saad AM Mes-Masson 2009 Over-expression of IkappaB-kinase-epsilon (IKKepsilon/IKKi) induces secretion of inflammatory cytokines in prostate cancer cell lines Prostate 69 706 718 19170126 10.1002/pros.20912 1:CAS:528:DC%2BD1MXmtFelsbo%3D
37. N Lamarche G Matton B Massie M Fontecave M Atta F Dumas P Gaudreau Y Langelier 1996 Production of the R2 subunit of ribonucleotide reductase from herpes simplex virus with prokaryotic and eukaryotic expression systems: higher activity of R2 produced by eukaryotic cells related to higher iron-binding capacity Biochem J 320 Pt 1 129 135 8947477 1:CAS:528:DyaK28Xnt12rsbk%3D
38. EA Cohen P Gaudreau P Brazeau Y Langelier 1986 Neutralization of herpes simplex virus ribonucleotide reductase activity by an oligopeptide-induced antiserum directed against subunit H2 J Virol 60 1130 1133 2431161 1:CAS:528:DyaL2sXivFansQ%3D%3D (Pubitemid 17179291)
39. JM Kyriakis J Avruch 2001 Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation Physiol Rev 81 807 869 11274345 1:CAS:528:DC%2BD3MXislCrsb8%3D (Pubitemid 32267078)
40. M Osaki M Oshimura H Ito 2004 PI3K-Akt pathway: its functions and alterations in human cancer Apoptosis 9 667 676 15505410 10.1023/B:APPT. 0000045801.15585.dd 1:CAS:528:DC%2BD2cXovVKqu70%3D (Pubitemid 40941196)
41. F Dida Y Li A Iwao T Deguchi E Azuma Y Komada 2008 Resistance to TRAIL-induced apoptosis caused by constitutional phosphorylation of Akt and PTEN in acute lymphoblastic leukemia cells Exp Hematol 36 1343 1353 18599181 10.1016/j.exphem.2008.04.011 1:CAS:528:DC%2BD1cXhtFylsLnK
42. B Pucci M Indelicato V Paradisi V Reali L Pellegrini M Aventaggiato NO Karpinich M Fini MA Russo JL Farber M Tafani 2009 ERK-1 MAP kinase prevents TNF-induced apoptosis through Bad phosphorylation and inhibition of Bax translocation in HeLa Cells J Cell Biochem 108 1166 1174 19777442 10.1002/jcb.22345 1:CAS:528:DC%2BD1MXhsV2gsL3F
43. JC Hunter CC Smith D Bose M Kulka R Broderick L Aurelian 1995 Intracellular internalization and signaling pathways triggered by the large subunit of HSV-2 ribonucleotide reductase (ICP10) Virology 210 345 360 7618272 10.1006/viro.1995.1351 1:CAS:528:DyaK2MXmvFWksbk%3D
44. S Luschen M Falk G Scherer S Ussat M Paulsen S Adam-Klages 2005 The Fas-associated death domain protein/caspase-8/c-FLIP signaling pathway is involved in TNF-induced activation of ERK Exp Cell Res 310 33 42 16129431 10.1016/j.yexcr.2005.07.022 (Pubitemid 41393685)
45. DR Alessi A Cuenda P Cohen DT Dudley AR Saltiel 1995 PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo J Biol Chem 270 27489 27494 7499206 10.1074/jbc.270.46. 27489 1:CAS:528:DyaK2MXpsFShsLg%3D
46. CJ Vlahos WF Matter KY Hui RF Brown 1994 A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) J Biol Chem 269 5241 5248 8106507 1:CAS:528:DyaK2cXjtFGit78%3D
47. J Liu A Lin 2005 Role of JNK activation in apoptosis: a double-edged sword Cell Res 15 36 42 15686625 10.1038/sj.cr.7290262 (Pubitemid 41653963)
48. S Hay G Kannourakis 2002 A time to kill: viral manipulation of the cell death program J Gen Virol 83 1547 1564 12075073 1:CAS:528:DC%2BD38Xlt1Wgu74%3D (Pubitemid 34716260)
49. J Bertin RC Armstrong S Ottilie DA Martin Y Wang S Banks GH Wang TG Senkevich ES Alnemri B Moss MJ Lenardo KJ Tomaselli JI Cohen 1997 Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis Proc Natl Acad Sci USA 94 1172 1176 9037025 10.1073/pnas.94.4.1172 1:CAS:528:DyaK2sXhtlGgt7c%3D (Pubitemid 27087823)
50. A Skaletskaya LM Bartle T Chittenden AL McCormick ES Mocarski VS Goldmacher 2001 A cytomegalovirus-encoded inhibitor of apoptosis that suppresses caspase-8 activation Proc Natl Acad Sci USA 98 7829 7834 11427719 10.1073/pnas.141108798 1:CAS:528:DC%2BD3MXlt1Kntrw%3D (Pubitemid 32642646)
51. T Fernandes-Alnemri RC Armstrong J Krebs SM Srinivasula L Wang F Bullrich LC Fritz JA Trapani KJ Tomaselli G Litwack ES Alnemri 1996 In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains Proc Natl Acad Sci USA 93 7464 7469 8755496 10.1073/pnas.93.15.7464 1:CAS:528:DyaK28XksFSku78%3D (Pubitemid 26277057)
52. M Chen A Orozco DM Spencer J Wang 2002 Activation of initiator caspases through a stable dimeric intermediate J Biol Chem 277 50761 50767 12399450 10.1074/jbc.M210356200 1:CAS:528:DC%2BD38Xps12ntLo%3D (Pubitemid 36042239)
53. MS Iordanov OP Ryabinina P Schneider BE Magun 2005 Two mechanisms of caspase 9 processing in double-stranded RNA- and virus-triggered apoptosis Apoptosis 10 153 166 15711931 10.1007/s10495-005-6070-y 1:CAS:528: DC%2BD2MXhsVWmsLk%3D (Pubitemid 40558123)
54. N Neznanov KP Chumakov A Ullrich VI Agol AV Gudkov 2002 Unstable receptors disappear from cell surface during poliovirus infection Med Sci Monit 8 BR391 BR396 12388911 1:CAS:528:DC%2BD38XptVOns7s%3D
55. M Tewari VM Dixit 1995 Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product J Biol Chem 270 3255 3260 7531702 10.1074/jbc.270.28.16526 1:CAS:528:DyaK2MXjslahu7s%3D
56. M Thome P Schneider K Hofmann H Fickenscher E Meinl F Neipel C Mattmann K Burns JL Bodmer M Schroter C Scaffidi PH Krammer ME Peter J Tschopp 1997 Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors Nature 386 517 521 9087414 10.1038/386517a0 1:CAS:528:DyaK2sXisVWgsrk%3D (Pubitemid 27164081)
57. K Saito K Meyer R Warner A Basu RB Ray R Ray 2006 Hepatitis C virus core protein inhibits tumor necrosis factor alpha-mediated apoptosis by a protective effect involving cellular FLICE inhibitory protein J Virol 80 4372 4379 16611896 10.1128/JVI.80.9.4372-4379.2006 1:CAS:528:DC%2BD28Xkt1Orsrw%3D
58. ML Goodkin ER Morton JA Blaho 2004 Herpes simplex virus infection and apoptosis Int Rev Immunol 23 141 172 14690858 10.1080/08830180490265574 1:CAS:528:DC%2BD3sXpvV2lsLw%3D (Pubitemid 38121750)
59. SQ Wales B Li JM Laing L Aurelian 2007 The herpes simplex virus type 2 gene ICP10PK protects from apoptosis caused by nerve growth factor deprivation through inhibition of caspase-3 activation and XIAP up-regulation J Neurochem 103 365 379 17877640 1:CAS:528:DC%2BD2sXht1Sjsr7N (Pubitemid 47404212)
60. S Hardy GG St-Onge E Joly Y Langelier M Prentki 2005 Oleate promotes the proliferation of breast cancer cells via the G protein-coupled receptor GPR40 J Biol Chem 280 13285 13291 15695516 10.1074/jbc.M410922200 1:CAS:528: DC%2BD2MXivV2ksL4%3D (Pubitemid 40517213)
61. M Filippova MM Johnson M Bautista V Filippov N Fodor SS Tungteakkhun K Williams PJ Duerksen-Hughes 2007 The large and small isoforms of human papillomavirus type 16 E6 bind to and differentially affect procaspase 8 stability and activity J Virol 81 4116 4129 17267478 10.1128/JVI.01924-06 1:CAS:528:DC%2BD2sXksVKksL8%3D (Pubitemid 46586906)
62. M Filippova L Parkhurst PJ Duerksen-Hughes 2004 The human papillomavirus 16 E6 protein binds to Fas-associated death domain and protects cells from Fas-triggered apoptosis J Biol Chem 279 25729 25744 15073179 10.1074/jbc.M401172200 1:CAS:528:DC%2BD2cXksFygtL0%3D (Pubitemid 38756837)
63. SH Chiou YP Yang JC Lin CH Hsu HC Jhang YT Yang CH Lee LL Ho WM Hsu HH Ku SJ Chen SS Chen MD Chang CW Wu LJ Juan 2006 The immediate early 2 protein of human cytomegalovirus (HCMV) mediates the apoptotic control in HCMV retinitis through up-regulation of the cellular FLICE-inhibitory protein expression J Immunol 177 6199 6206 17056549 1:CAS:528:DC%2BD28XhtFSns7rE (Pubitemid 44628838)
64. V Galvan B Roizman 1998 Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner Proc Natl Acad Sci USA 95 3931 3936 9520470 10.1073/pnas.95.7.3931 1:CAS:528:DyaK1cXitlKjurY%3D (Pubitemid 28173231)
65. AL McCormick A Skaletskaya PA Barry ES Mocarski VS Goldmacher 2003 Differential function and expression of the viral inhibitor of caspase 8-induced apoptosis (vICA) and the viral mitochondria-localized inhibitor of apoptosis (vMIA) cell death suppressors conserved in primate and rodent cytomegaloviruses Virology 316 221 233 14644605 10.1016/j.virol.2003.07.003 1:CAS:528: DC%2BD3sXpsVSlsb8%3D (Pubitemid 37468526)
66. N Keller J Mares O Zerbe MG Grutter 2009 Structural and biochemical studies on procaspase-8: new insights on initiator caspase activation Structure 17 438 448 19278658 10.1016/j.str.2008.12.019 1:CAS:528:DC%2BD1MXivVKisbY%3D
67. PE Carrington C Sandu Y Wei JM Hill G Morisawa T Huang E Gavathiotis Y Wei MH Werner 2006 The structure of FADD and its mode of interaction with procaspase-8 Mol Cell 22 599 610 16762833 10.1016/j.molcel.2006.04.018 1:CAS:528:DC%2BD28XmtFSrurk%3D (Pubitemid 43817600)
68. D Lembo W Brune 2009 Tinkering with a viral ribonucleotide reductase Trends Biochem Sci 34 25 32 18990579 10.1016/j.tibs.2008.09.008 1:CAS:528:DC%2BD1MXktl2gsQ%3D%3D
69. L Galluzzi O Kepp E Morselli I Vitale L Senovilla M Pinti L Zitvogel G Kroemer 2010 Viral strategies for the evasion of immunogenic cell death J Intern Med 267 526 542 20433579 10.1111/j.1365-2796.2010.02223.x 1:CAS:528: DC%2BC3cXmsleqt7o%3D
70. A Kather MJ Raftery G Devi-Rao J Lippmann T Giese RM Sandri-Goldin G Schonrich 2010 Herpes simplex virus type 1 (HSV-1)-induced apoptosis in human dendritic cells as a result of downregulation of cellular FLICE-inhibitory protein and reduced expression of HSV-1 antiapoptotic latency-associated transcript sequences J Virol 84 1034 1046 19906927 10.1128/JVI.01409-09 1:CAS:528:DC%2BC3cXisFyksrk%3D
71. P Lundberg PV Welander CK Edwards 3rd N van Rooijen E Cantin 2007 Tumor necrosis factor (TNF) protects resistant C57BL/6 mice against herpes simplex virus-induced encephalitis independently of signaling via TNF receptor 1 or 2 J Virol 81 1451 1460 17108044 10.1128/JVI.02243-06 1:CAS:528:DC%2BD2sXhtFCnsrY%3D (Pubitemid 46167866)