Structures of reverse transcriptase pre- and post-excision complexes shed new light on HIV-1 AZT resistance

Viruses

Volumn 3, Issue 1, 2011, Pages 20-25

  Scott, Walter A ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

AZT resistance; AZTppppA; HIV; Nucleotide excision; Reverse transcriptase

Indexed keywords

ADENOSINE PHOSPHATE; ARGININE; DIADENOSINE TETRAPHOSPHATE; DOUBLE STRANDED DNA; NUCLEOSIDE TRIPHOSPHATE; RNA DIRECTED DNA POLYMERASE; TYROSINE; ZIDOVUDINE;

ANTIVIRAL RESISTANCE; ARTICLE; BINDING SITE; CONTROLLED STUDY; CROSS LINKING; CRYSTAL STRUCTURE; ENZYME STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MUTATION; NONHUMAN; POLYMERIZATION; PROTEIN PROTEIN INTERACTION;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; DRUG RESISTANCE, VIRAL; HIV REVERSE TRANSCRIPTASE; HIV-1; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; ZIDOVUDINE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 79952182044     PISSN: None     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v3010020     Document Type: Article

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