c-myc proto-oncogene expression in hemophilic synovitis: In vitro studies of the effects of iron and ceramide

Blood

Volumn 100, Issue 3, 2002, Pages 912-916

  Wen, Fei Qiu ^a   Jabbar, Adnan A ^a   Chen, Yi Xin ^a   Kazarian, Tamara ^a   Patel, Dharmesh A ^a   Valentino, Leonard A ^a,b  

^a RUSH UNIVERSITY   (United States)

^b Rush Children's Hospital and Rush University Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; CERAMIDE; CITRATE SODIUM; FERRIC CITRATE; HEMOSIDERIN; IRON; ONCOPROTEIN; SPHINGOLIPID;

APOPTOSIS; ARTICLE; BLOOD CLOTTING FACTOR DEFICIENCY; CANCER INVASION; CELL DESTRUCTION; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; FIBROBLAST; GENE EXPRESSION; HEMOPHILIA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HYPERPLASIA; IN VITRO STUDY; NEOVASCULARIZATION (PATHOLOGY); PRIORITY JOURNAL; PROTO ONCOGENE; RECURRENT DISEASE; SYNOVITIS; SYNOVIUM; TUMOR GROWTH;

EID: 0036682499     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-02-0390     Document Type: Article

References (32)

1. Experimental hemarthrosis. The response of canine knees to injections of autologous blood
2. The nature of iron deposits in haemophilic synovitis. An immunohistochemical, ultrastructural and x-ray microanalytical study
3. The pathogenesis of chronic haemophilic arthropathy
4. Iron deposits and catabolic properties of synovial tissue from patients with haemophilia
5. Stimulation of human synovial cell DNA synthesis by iron
6. c-Myc protein in the rabbit growth plate. Changes in immunolocalisation with age and possible roles from proliferation to apoptosis
7. Promotion of growth and apoptosis in c-myc nullizygous fibroblasts by other members of the myc oncoprotein family
8. Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis
9. Induction of apoptosis in fibroblasts by c-myc protein
10. Hemophilic arthropathy in dogs
11. Recent insights into the pathogenesis of the proliferative lesion in rheumatoid arthritis
12. Hypothesis: In vitro evidence for the invasive and tumor-like properties of the rheumatoid pannus
13. Oncoprotein expression in human synovial tissue: An immunohistochemical study of different types of arthritis
14. Regulation of expression of a human lymphoid cell surface marker by iron
15. Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation
16. Programmed cell death induced by ceramide
17. Haemophilic arthritis
18. Mechanisms of joint damage in an experimental model of hemophilic arthritis
19. Experimental hemarthrosis in the knee of the mature canine
20. Iron in cancer
21. Growth of embryonal carcinoma cells in serum-free medium
22. The importance of iron in rheumatoid disease
23. The effect of synovial iron on the progression of rheumatoid disease. A histologic assessment of patients with early rheumatoid synovitis
24. Synovial iron deposition in rheumatoid arthritis
25. Oncogenes in rheumatoid arthritis
26. C-myc antisense oligodeoxynucleotides can induce apoptosis and down-regulate Fas expression in rheumatoid synoviocytes
27. Decreased expression of c-myc oncoprotein by peripheral blood mononuclear cells in thalassaemia patients receiving desferrioxamine
28. Suppression of HL-60 cell proliferation by deferoxamine: Changes in c-myc expression
29. Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-MYC
30. Reduction of ribonucleotides
31. Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide
32. Apoptosis induction in synovial fibroblasts by ceramide: In vitro and in vivo effects