-
1
-
-
34848904494
-
Myelodysplastic syndrome with isolated deletion of chromosome 20q: an indolent disease with minimal morphological dysplasia and frequent thrombocytopenic presentation
-
Gupta R., Soupir C.P., Johari V., Hasserjian R.P. Myelodysplastic syndrome with isolated deletion of chromosome 20q: an indolent disease with minimal morphological dysplasia and frequent thrombocytopenic presentation. Br J Haematol 2007, 139:265-268.
-
(2007)
Br J Haematol
, vol.139
, pp. 265-268
-
-
Gupta, R.1
Soupir, C.P.2
Johari, V.3
Hasserjian, R.P.4
-
2
-
-
34247646400
-
The incidence and impact of thrombocytopenia in myelodysplastic syndromes
-
Kantarjian H., Giles F., List A., Lyons R., Sekeres M.A., Pierce S., et al. The incidence and impact of thrombocytopenia in myelodysplastic syndromes. Cancer 2007, 109:1705-1714.
-
(2007)
Cancer
, vol.109
, pp. 1705-1714
-
-
Kantarjian, H.1
Giles, F.2
List, A.3
Lyons, R.4
Sekeres, M.A.5
Pierce, S.6
-
3
-
-
0034050412
-
Defective megakaryocytic development in myelodysplastic syndromes
-
Hofmann W.K., Kalina U., Koschmieder S., Seipelt G., Hoelzer D., Ottmann O.G. Defective megakaryocytic development in myelodysplastic syndromes. Leuk Lymphoma 2000, 38:13-19.
-
(2000)
Leuk Lymphoma
, vol.38
, pp. 13-19
-
-
Hofmann, W.K.1
Kalina, U.2
Koschmieder, S.3
Seipelt, G.4
Hoelzer, D.5
Ottmann, O.G.6
-
4
-
-
18244369756
-
Increased peripheral platelet destruction and caspase-3-independent programmed cell death of bone marrow megakaryocytes in myelodysplastic patients
-
Houwerzijl E.J., Blom N.R., van der Want J.J., Louwes H., Esselink M.T., Smit J.W., et al. Increased peripheral platelet destruction and caspase-3-independent programmed cell death of bone marrow megakaryocytes in myelodysplastic patients. Blood 2005, 105:3472-3479.
-
(2005)
Blood
, vol.105
, pp. 3472-3479
-
-
Houwerzijl, E.J.1
Blom, N.R.2
van der Want, J.J.3
Louwes, H.4
Esselink, M.T.5
Smit, J.W.6
-
5
-
-
13544266567
-
Megakaryocytopoiesis and apoptosis in patients with myelodysplastic syndromes
-
Li X., Pu Q. Megakaryocytopoiesis and apoptosis in patients with myelodysplastic syndromes. Leuk Lymphoma 2005, 46:387-391.
-
(2005)
Leuk Lymphoma
, vol.46
, pp. 387-391
-
-
Li, X.1
Pu, Q.2
-
6
-
-
0034981980
-
Role of splenectomy in the treatment of myelodysplastic syndromes with peripheral thrombocytopenia: a report on six cases
-
Bourgeois E., Caulier M.T., Rose C., Dupriez B., Bauters F., Fenaux P. Role of splenectomy in the treatment of myelodysplastic syndromes with peripheral thrombocytopenia: a report on six cases. Leukemia 2001, 15:950-953.
-
(2001)
Leukemia
, vol.15
, pp. 950-953
-
-
Bourgeois, E.1
Caulier, M.T.2
Rose, C.3
Dupriez, B.4
Bauters, F.5
Fenaux, P.6
-
7
-
-
70449726874
-
Effect of the nonpeptide thrombopoietin receptor agonist eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome
-
Will B., Kawahara M., Luciano J.P., Bruns I., Parekh S., Erickson-Miller C.L., et al. Effect of the nonpeptide thrombopoietin receptor agonist eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome. Blood 2009, 114:3899-3908.
-
(2009)
Blood
, vol.114
, pp. 3899-3908
-
-
Will, B.1
Kawahara, M.2
Luciano, J.P.3
Bruns, I.4
Parekh, S.5
Erickson-Miller, C.L.6
-
8
-
-
75749124291
-
Safety and efficacy of romiplostim in patients with lower-risk myelodysplastic syndrome and thrombocytopenia
-
Kantarjian H., Fenaux P., Sekeres M.A., Becker P.S., Boruchov A., Bowen D., et al. Safety and efficacy of romiplostim in patients with lower-risk myelodysplastic syndrome and thrombocytopenia. J Clin Oncol 2010, 28(3):437-444.
-
(2010)
J Clin Oncol
, vol.28
, Issue.3
, pp. 437-444
-
-
Kantarjian, H.1
Fenaux, P.2
Sekeres, M.A.3
Becker, P.S.4
Boruchov, A.5
Bowen, D.6
-
9
-
-
36549001698
-
Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura
-
Bussel J.B., Cheng G., Saleh M.N., Psaila B., Kovaleva L., Meddeb B., et al. Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura. N Engl J Med 2007, 357:2237-2247.
-
(2007)
N Engl J Med
, vol.357
, pp. 2237-2247
-
-
Bussel, J.B.1
Cheng, G.2
Saleh, M.N.3
Psaila, B.4
Kovaleva, L.5
Meddeb, B.6
-
10
-
-
33750035507
-
AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP
-
Bussel J.B., Kuter D.J., George J.N., McMillan R., Aledort L.M., Conklin G.T., et al. AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP. N Engl J Med 2006, 355:1672-1681.
-
(2006)
N Engl J Med
, vol.355
, pp. 1672-1681
-
-
Bussel, J.B.1
Kuter, D.J.2
George, J.N.3
McMillan, R.4
Aledort, L.M.5
Conklin, G.T.6
-
11
-
-
0038107361
-
Impaired granulocytopoiesis in patients with chronic idiopathic neutropenia is associated with increased apoptosis of bone marrow myeloid progenitor cells
-
Papadaki H.A., Eliopoulos A.G., Kosteas T., Gemetzi C., Damianaki A., Koutala H., et al. Impaired granulocytopoiesis in patients with chronic idiopathic neutropenia is associated with increased apoptosis of bone marrow myeloid progenitor cells. Blood 2003, 101:2591-2600.
-
(2003)
Blood
, vol.101
, pp. 2591-2600
-
-
Papadaki, H.A.1
Eliopoulos, A.G.2
Kosteas, T.3
Gemetzi, C.4
Damianaki, A.5
Koutala, H.6
-
12
-
-
0029866409
-
The use of 7-amino actinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques
-
Philpott N.J., Turner A.J., Scopes J., Westby M., Marsh J.C., Gordon-Smith E.C., et al. The use of 7-amino actinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques. Blood 1996, 87:2244-2251.
-
(1996)
Blood
, vol.87
, pp. 2244-2251
-
-
Philpott, N.J.1
Turner, A.J.2
Scopes, J.3
Westby, M.4
Marsh, J.C.5
Gordon-Smith, E.C.6
-
13
-
-
0036493402
-
Bone marrow progenitor cell reserve and function and stromal cell function are defective in rheumatoid arthritis: evidence for a tumor necrosis factor alpha-mediated effect
-
Papadaki H.A., Kritikos H.D., Gemetzi C., Koutala H., Marsh J.C., Boumpas D.T., et al. Bone marrow progenitor cell reserve and function and stromal cell function are defective in rheumatoid arthritis: evidence for a tumor necrosis factor alpha-mediated effect. Blood 2002, 99:1610-1619.
-
(2002)
Blood
, vol.99
, pp. 1610-1619
-
-
Papadaki, H.A.1
Kritikos, H.D.2
Gemetzi, C.3
Koutala, H.4
Marsh, J.C.5
Boumpas, D.T.6
-
14
-
-
0033761459
-
In vitro proliferation and differentiation of megakaryocytic progenitors in patients with aplastic anemia, paroxysmal nocturnal hemoglobinuria, and the myelodysplastic syndromes
-
Cox C.V., Killick S.B., Patel S., Elebute M.O., Marsh J.C., Gordon-Smith E.C., et al. In vitro proliferation and differentiation of megakaryocytic progenitors in patients with aplastic anemia, paroxysmal nocturnal hemoglobinuria, and the myelodysplastic syndromes. Stem Cells 2000, 18:428-434.
-
(2000)
Stem Cells
, vol.18
, pp. 428-434
-
-
Cox, C.V.1
Killick, S.B.2
Patel, S.3
Elebute, M.O.4
Marsh, J.C.5
Gordon-Smith, E.C.6
-
15
-
-
33747426275
-
Impaired megakaryopoiesis in patients with chronic idiopathic neutropenia is associated with increased transforming growth factor beta1 production in the bone marrow
-
Psyllaki M., Damianaki A., Gemetzi C., Pyrovolaki K., Eliopoulos G.D., Papadaki H.A. Impaired megakaryopoiesis in patients with chronic idiopathic neutropenia is associated with increased transforming growth factor beta1 production in the bone marrow. Br J Haematol 2006, 134:624-631.
-
(2006)
Br J Haematol
, vol.134
, pp. 624-631
-
-
Psyllaki, M.1
Damianaki, A.2
Gemetzi, C.3
Pyrovolaki, K.4
Eliopoulos, G.D.5
Papadaki, H.A.6
-
16
-
-
0034024416
-
Effect of thrombopoietin on proliferation of blasts from patients with myelodysplastic syndromes
-
Luo S.S., Ogata K., Yokose N., Kato T., Dan K. Effect of thrombopoietin on proliferation of blasts from patients with myelodysplastic syndromes. Stem Cells 2000, 18:112-119.
-
(2000)
Stem Cells
, vol.18
, pp. 112-119
-
-
Luo, S.S.1
Ogata, K.2
Yokose, N.3
Kato, T.4
Dan, K.5
-
17
-
-
0033797720
-
Alteration of c-mpl-mediated signal transduction in CD34(+) cells from patients with myelodysplastic syndromes
-
Kalina U., Hofmann W.K., Koschmieder S., Wagner S., Kauschat D., Hoelzer D., et al. Alteration of c-mpl-mediated signal transduction in CD34(+) cells from patients with myelodysplastic syndromes. Exp Hematol 2000, 28:1158-1163.
-
(2000)
Exp Hematol
, vol.28
, pp. 1158-1163
-
-
Kalina, U.1
Hofmann, W.K.2
Koschmieder, S.3
Wagner, S.4
Kauschat, D.5
Hoelzer, D.6
-
18
-
-
19944432021
-
Discovery and characterization of a selective, nonpeptidyl thrombopoietin receptor agonist
-
Erickson-Miller C.L., DeLorme E., Tian S.S., Hopson C.B., Stark K., Giampa L., et al. Discovery and characterization of a selective, nonpeptidyl thrombopoietin receptor agonist. Exp Hematol 2005, 33:85-93.
-
(2005)
Exp Hematol
, vol.33
, pp. 85-93
-
-
Erickson-Miller, C.L.1
DeLorme, E.2
Tian, S.S.3
Hopson, C.B.4
Stark, K.5
Giampa, L.6
-
19
-
-
60249099882
-
Effect of eltrombopag on platelet counts and bleeding during treatment of chronic idiopathic thrombocytopenic purpura: a randomised, double-blind, placebo-controlled trial
-
Bussel J.B., Provan D., Shamsi T., Cheng G., Psaila B., Kovaleva L., et al. Effect of eltrombopag on platelet counts and bleeding during treatment of chronic idiopathic thrombocytopenic purpura: a randomised, double-blind, placebo-controlled trial. Lancet 2009, 373:641-648.
-
(2009)
Lancet
, vol.373
, pp. 641-648
-
-
Bussel, J.B.1
Provan, D.2
Shamsi, T.3
Cheng, G.4
Psaila, B.5
Kovaleva, L.6
-
20
-
-
36549047972
-
Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C
-
McHutchison J.G., Dusheiko G., Shiffman M.L., Rodriguez-Torres M., Sigal S., Bourliere M., et al. Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C. N Engl J Med 2007, 357:2227-2236.
-
(2007)
N Engl J Med
, vol.357
, pp. 2227-2236
-
-
McHutchison, J.G.1
Dusheiko, G.2
Shiffman, M.L.3
Rodriguez-Torres, M.4
Sigal, S.5
Bourliere, M.6
-
21
-
-
62549153611
-
Preclinical activity of eltrombopag (SB-497115), an oral, nonpeptide thrombopoietin receptor agonist
-
Erickson-Miller C.L., Delorme E., Tian S.S., Hopson C.B., Landis A.J., Valoret E.I., et al. Preclinical activity of eltrombopag (SB-497115), an oral, nonpeptide thrombopoietin receptor agonist. Stem Cells 2009, 27:424-430.
-
(2009)
Stem Cells
, vol.27
, pp. 424-430
-
-
Erickson-Miller, C.L.1
Delorme, E.2
Tian, S.S.3
Hopson, C.B.4
Landis, A.J.5
Valoret, E.I.6
-
22
-
-
66749122752
-
Thrombopoietin and thrombopoietin mimetics in the treatment of thrombocytopenia
-
Kuter D.J. Thrombopoietin and thrombopoietin mimetics in the treatment of thrombocytopenia. Annu Rev Med 2009, 60:193-206.
-
(2009)
Annu Rev Med
, vol.60
, pp. 193-206
-
-
Kuter, D.J.1
-
23
-
-
67849104655
-
Development of thrombopoietin receptor agonists for clinical use
-
Ikeda Y., Miyakawa Y. Development of thrombopoietin receptor agonists for clinical use. J Thromb Haemost 2009, 7(Suppl. 1):239-244.
-
(2009)
J Thromb Haemost
, vol.7
, Issue.SUPPL. 1
, pp. 239-244
-
-
Ikeda, Y.1
Miyakawa, Y.2
-
24
-
-
77955271313
-
Reduced proliferation of non-megakaryocytic acute myelogenous leukemia and other leukemia and lymphoma cell lines in response to eltrombopag
-
Erickson-Miller C.L., Kirchner J., Aivado M., May R., Payne P., Chadderton A. Reduced proliferation of non-megakaryocytic acute myelogenous leukemia and other leukemia and lymphoma cell lines in response to eltrombopag. Leuk Res 2010, 10.1016/j.leukres.2010.02.005.
-
(2010)
Leuk Res
-
-
Erickson-Miller, C.L.1
Kirchner, J.2
Aivado, M.3
May, R.4
Payne, P.5
Chadderton, A.6
-
25
-
-
0029063170
-
Prognostic value of c-mpl expression in myelodysplastic syndromes
-
Bouscary D., Preudhomme C., Ribrag V., Melle J., Viguie F., Picard F., et al. Prognostic value of c-mpl expression in myelodysplastic syndromes. Leukemia 1995, 9:783-788.
-
(1995)
Leukemia
, vol.9
, pp. 783-788
-
-
Bouscary, D.1
Preudhomme, C.2
Ribrag, V.3
Melle, J.4
Viguie, F.5
Picard, F.6
-
26
-
-
68549092703
-
Comparative analyses of the small molecule thrombopoietin receptor agonist eltrombopag and thrombopoietin on in vitro platelet function
-
Erhardt J.A., Erickson-Miller C.L., Aivado M., Abboud M., Pillarisetti K., Toomey J.R. Comparative analyses of the small molecule thrombopoietin receptor agonist eltrombopag and thrombopoietin on in vitro platelet function. Exp Hematol 2009, 37:1030-1037.
-
(2009)
Exp Hematol
, vol.37
, pp. 1030-1037
-
-
Erhardt, J.A.1
Erickson-Miller, C.L.2
Aivado, M.3
Abboud, M.4
Pillarisetti, K.5
Toomey, J.R.6
-
27
-
-
34249719511
-
Phase I clinical study of eltrombopag, an oral, non-peptide thrombopoietin receptor agonist
-
Jenkins J.M., Williams D., Deng Y., Uhl J., Kitchen V., Collins D. Phase I clinical study of eltrombopag, an oral, non-peptide thrombopoietin receptor agonist. Blood 2007, 109:4739-4741.
-
(2007)
Blood
, vol.109
, pp. 4739-4741
-
-
Jenkins, J.M.1
Williams, D.2
Deng, Y.3
Uhl, J.4
Kitchen, V.5
Collins, D.6
|