Bone marrow progenitor cell reserve and function and stromal cell function are defective in rheumatoid arthritis: Evidence for a tumor necrosis factor alpha-mediated effect

Blood

Volumn 99, Issue 5, 2002, Pages 1610-1619

  Papadaki, Helen A ^a,b   Kritikos, Heraklis D ^a,b   Gemetzi, Claudia ^a,b   Koutala, Helen ^a,b   Marsh, Judith C W ^a,b   Boumpas, Dimitrios T ^a,b   Eliopoulos, George D ^a,b  

^a UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

^b ST GEORGE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRHEUMATIC AGENT; CD34 ANTIGEN; CORTICOSTEROID; CYCLOSPORIN A; HYDROXYCHLOROQUINE; IMMUNOGLOBULIN G1; INFLIXIMAB; METHOTREXATE; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; PREDNISOLONE; SALAZOSULFAPYRIDINE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANEMIA; APOPTOSIS; ARTHRITIS; ARTICLE; BONE MARROW CULTURE; CLINICAL ARTICLE; CLINICAL TRIAL; FEMALE; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNOPHENOTYPING; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; STROMA CELL; TREATMENT OUTCOME;

EID: 0036493402     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.5.1610     Document Type: Article

References (47)

1. Bone marrow stromal cells contribute to synovial cell proliferation in rats with collagen induced arthritis
2. Enhanced expression of CD14 antigen on myeloid lineage cells derived from the bone marrow of patients with severe rheumatoid arthritis
3. Expression and function of wingless and frizzled homologs in rheumatoid arthritis
4. Distinct alterations in lineage committed progenitor cells exist in the peripheral blood of patients with rheumatoid arthritis and primary Sjogren's syndrome
5. Establishment of nurse-like stromal cells from bone marrow of patients with rheumatoid arthritis: Indication of characteristic bone marrow microenvironment in patients with rheumatoid arthritis
6. Rheumatoid arthritis as a bone marrow disorder
7. Autoimmune diseases as stem cell disorders: Normal stem cell transplant for their treatment
8. Detection of myeloid precursors (granulocyte/macrophage colony forming units) in the bone marrow adjacent to rheumatoid arthritis joints
9. Phenotypic characteristics of bone marrow cells in patients with rheumatoid arthritis
10. Accelerated generation of CD14+ monocyte-lineage cells from the bone marrow of rheumatoid arthritis patients
11. Elevated levels of inflammatory cytokines in bone marrow of patients with rheumatoid arthritis and anemia of chronic disease
12. Human bone marrow stromal cell lines from myeloma and rheumatoid arthritis that can support murine pre-B cell growth
13. Blood and marrow stem cell transplants in autoimmune disease: A consensus report written on behalf of the European League Against Rheumatism (EULAR) and the European Group for Blood and Marrow Transplantation (EBMT)
14. Autologous hematopoietic stem cell transplantation in refractory rheumatoid arthritis: Sustained response in two of four patients
15. Intensified-dose (4 gm/m2) cyclophosphamide and granulocyte colony-stimulating factor administration for hematopoietic stem cell mobilization in refractory rheumatoid arthritis
16. Hematopoietic stem cell transplantation in rheumatic diseases
17. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
18. Activity indices in rheumatoid arthritis
19. The hierarchy of quality-of-life assessment, the Health Assessment Questionnaire (HAQ), and issues mandating development of a toxicity index
20. Construction and initial characterization of a mouse-human chimeric anti-TNF antibody
21. The use of 7-amino actinomycin D in identifying apoptosis: Simplicity of use and broad spectrum of application compared with other techniques
22. Clonal and long-term cultures using human bone marrow
23. The hematopoietic defect in aplastic anemia assessed by long-term marrow culture
24. Long-term culture of aplastic anaemia bone marrow
25. In vitro assessment of marrow stem cell and stromal cell function in aplastic anaemia
26. Functional expression of Fas antigen (CD95) on hematopoietic progenitor cells
27. + cells
28. Immune suppression of hematopoiesis
29. Elevated activity of myeloid growth factor in bone marrow adjacent to joints affected by rheumatoid arthritis
30. Remarkable elevation of interleukin 6 and interleukin 8 levels in the bone marrow serum of patients with rheumatoid arthritis
31. Analysis of lymphocyte subsets of bone marrow in patients with rheumatoid arthritis by two colour immunofluorescence and flow cytometry
32. Abnormalities in bone marrow mononuclear cells in patients with rheumatoid arthritis
33. Rheumatoid arthritis: Opposing actions of haemopoietic growth factors and slow-acting anti-rheumatic drugs
34. Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood
35. Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemia
36. Fas/Apo-1 expression and apoptosis in patients with myelodysplastic syndromes
37. Transforming growth factor-α tumor necrosis factor-α and macrophage inflammatory protein-1α are bidirectional regulators of hematopoietic cell growth
38. Sensitization of hematopoietic stem and progenitor cells to trimetrexate using nucleoside transport inhibitors
39. The hematological effects of folate analogs: Implications for using the dihydrofolate reductase gene for in vivo selection
40. Glucocorticoids and cyclosporine induce apoptosis in mitogen-activated human peripheral mononuclear cells
41. Corticosteroids alter hematopoiesis in vitro by enhancing human monocyte secretion of granulocyte colony-stimulating factor
42. The glucocorticoid receptor cooperates with the erythropoietin receptor and c-Kit to enhance and sustain proliferation of erythroid progenitors in vitro
43. Blood-derived macrophage layers in the presence of hydrocortisone support myeloid progenitors in long-term cultures of CD34+ cord blood and bone marrow cells
44. Activation and differentiation of myelomonocytic cells in rheumatoid arthritis and healthy individuals: Evidence for antagonistic in vitro regulation by interferon-gamma and tumor necrosis factor alpha, granulocyte monocyte colony stimulating factor and interleukin 1
45. Establishment and characterization of nurse-like stromat cell lines from synovial tissues of patients with rheumatoid arthritis
46. Composition and function of peripheral blood stem and progenitor cell harvests from patients with severe active rheumatoid arthritis