Selecting surfactants for the maximum inhibition of the activity of the multi drug resistance efflux pump transporter, P-glycoprotein: Conceptual development

Journal of Excipients and Food Chemicals

Volumn 1, Issue 3, 2010, Pages 51-59

  Prakash, Apte Shireesh ^a  

^a Alcon Research Inc   (United States)

Author keywords

Chemoresistance; CMC; Excipient; HLB; Multidrug resistance; P glycoprotein; Prediction; Surfactant

Indexed keywords

3 [(3 CHOLAMIDOPROPYL)DIMETHYLAMMONIO] 1 PROPANESULFONIC ACID; 3 [(3 CHOLAMIDOPROPYL)DIMETHYLAMMONIO] 2 HYDROXY 1 PROPANESULFONIC ACID; BENZALKONIUM CHLORIDE; CETRIMIDE; CREMOPHOR; DEOXYCHOLATE SODIUM; DOCUSATE SODIUM; DODECYL SULFATE SODIUM; DOXORUBICIN; EPIRUBICIN; GLYCOPROTEIN P; LUBROL; MACROGOL; MACROGOL STEARATE; OCTYL GLUCOSIDE; POLOXAMER; POLYETHYLENE GLYCOL HYDROXYSTEARATE; POLYSORBATE 20; POLYSORBATE 80; RHODAMINE 123; SORBITAN OLEATE; SURFACTANT; TOCOFERSOLAN; TRITON X 100; TRITON X 114; UNCLASSIFIED DRUG; VERAPAMIL;

CANCER RESISTANCE; CHEMICAL PHENOMENA; CONCENTRATION RESPONSE; CONCEPTUAL FRAMEWORK; CRITICAL MICELLE CONCENTRATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SOLUBILITY; DRUG UPTAKE; HUMAN; HYDROPHILIC LIPOPHILIC BALANCE; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; LEARNING ALGORITHM; MOLECULAR INTERACTION; MOLECULAR WEIGHT; MULTIDRUG RESISTANCE; NONHUMAN; PHYSICAL CHEMISTRY; REACTION OPTIMIZATION; REVIEW;

EID: 79952098499     PISSN: None     EISSN: 21502668     Source Type: Journal    
DOI: None     Document Type: Review

References (25)

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