-
1
-
-
33745899048
-
Alternative splicing: new insights from global analyses
-
Blencowe BJ. Alternative splicing: new insights from global analyses. Cell 2006; 126: 37-47.
-
(2006)
Cell
, vol.126
, pp. 37-47
-
-
Blencowe, B.J.1
-
2
-
-
7244245762
-
Finishing the euchromatic sequence of the human genome
-
International Human Genome Sequencing Consortium. . ; -.
-
International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature 2004; 431: 931-945.
-
(2004)
Nature
, vol.431
, pp. 931-945
-
-
-
3
-
-
0035393343
-
Genome-wide detection of alternative splicing in expressed sequences of human genes
-
Modrek B, Resch A, Grasso C, Lee C. Genome-wide detection of alternative splicing in expressed sequences of human genes. Nucleic Acids Res 2001; 29: 2850-2859.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 2850-2859
-
-
Modrek, B.1
Resch, A.2
Grasso, C.3
Lee, C.4
-
5
-
-
0013394889
-
Mechanisms of alternative pre-messenger RNA splicing
-
Black DL. Mechanisms of alternative pre-messenger RNA splicing. Annu Rev Biochem 2003; 72: 291-336.
-
(2003)
Annu Rev Biochem
, vol.72
, pp. 291-336
-
-
Black, D.L.1
-
6
-
-
57149111212
-
Cancer-associated splicing variants of the CDCA1 and MSMB genes expressed in cancer cell lines and surgically resected gastric cancer tissues
-
Ohnuma S, Miura K, Horii A et al. Cancer-associated splicing variants of the CDCA1 and MSMB genes expressed in cancer cell lines and surgically resected gastric cancer tissues. Surgery 2009; 145: 57-68.
-
(2009)
Surgery
, vol.145
, pp. 57-68
-
-
Ohnuma, S.1
Miura, K.2
Horii, A.3
-
7
-
-
0001468848
-
The RNA World II
-
In: Gesteland RF, Cech TR, Atkins JF, eds. . New York, NY: Cold Spring Harbor Laboratory Press, -.
-
Burge CB, Tuschl T, Sharp PA. Splicing of precursors to mRNAs by the spliceosomes. In: Gesteland RF, Cech TR, Atkins JF, eds. The RNA World II. New York, NY: Cold Spring Harbor Laboratory Press, 1999; 525-560.
-
(1999)
Splicing of precursors to mRNAs by the spliceosomes
, pp. 525-560
-
-
Burge, C.B.1
Tuschl, T.2
Sharp, P.A.3
-
8
-
-
60349104299
-
The spliceosome: design principles of a dynamic RNP machine
-
Wahl MC, Will CL, Lührmann R. The spliceosome: design principles of a dynamic RNP machine. Cell 2009; 136: 701-718.
-
(2009)
Cell
, vol.136
, pp. 701-718
-
-
Wahl, M.C.1
Will, C.L.2
Lührmann, R.3
-
9
-
-
70350569286
-
Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches
-
Chen M, Manley JL. Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches. Nat Rev Mol Cell Biol 2009; 10: 741-754.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 741-754
-
-
Chen, M.1
Manley, J.L.2
-
10
-
-
0033153348
-
hnRNP complexes: composition, structure, and function
-
Krecic AM, Swanson MS. hnRNP complexes: composition, structure, and function. Curr Opin Cell Biol 1999; 11: 363-371.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 363-371
-
-
Krecic, A.M.1
Swanson, M.S.2
-
11
-
-
33947541694
-
Alternative splicing: an emerging topic in molecular and clinical oncology
-
Pajares MJ, Ezponda T, Catena R, Calvo A, Pio R, Montuenga LM. Alternative splicing: an emerging topic in molecular and clinical oncology. Lancet Oncol 2007; 8: 349-357.
-
(2007)
Lancet Oncol
, vol.8
, pp. 349-357
-
-
Pajares, M.J.1
Ezponda, T.2
Catena, R.3
Calvo, A.4
Pio, R.5
Montuenga, L.M.6
-
12
-
-
0027160003
-
Distinct functions of SR proteins in alternative pre-mRNA splicing
-
Zahler AM, Neugebauer KM, Lane WS, Roth MB. Distinct functions of SR proteins in alternative pre-mRNA splicing. Science 1993; 260: 219-222.
-
(1993)
Science
, vol.260
, pp. 219-222
-
-
Zahler, A.M.1
Neugebauer, K.M.2
Lane, W.S.3
Roth, M.B.4
-
13
-
-
0036534129
-
Alternative splicing: multiple control mechanisms and involvement in human disease
-
Cáceres JF, Kornblihtt AR. Alternative splicing: multiple control mechanisms and involvement in human disease. Trends Genet 2002; 18: 186-193.
-
(2002)
Trends Genet
, vol.18
, pp. 186-193
-
-
Cáceres, J.F.1
Kornblihtt, A.R.2
-
14
-
-
61649087689
-
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing
-
Warzecha CC, Sato TK, Nabet B, Hogenesch JB, Carstens RP. ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Mol Cell 2009; 33: 591-601.
-
(2009)
Mol Cell
, vol.33
, pp. 591-601
-
-
Warzecha, C.C.1
Sato, T.K.2
Nabet, B.3
Hogenesch, J.B.4
Carstens, R.P.5
-
15
-
-
26944489645
-
Building specificity with nonspecific RNA-binding proteins
-
Singh R, Valcárcel J. Building specificity with nonspecific RNA-binding proteins. Nat Struct Mol Biol 2005; 12: 645-653.
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 645-653
-
-
Singh, R.1
Valcárcel, J.2
-
16
-
-
48149095822
-
Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense?
-
McGlincy NJ, Smith CW. Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense? Trends Biochem Sci 2008; 33: 385-393.
-
(2008)
Trends Biochem Sci
, vol.33
, pp. 385-393
-
-
McGlincy, N.J.1
Smith, C.W.2
-
18
-
-
0034908554
-
Nomenclature for the description of human sequence variations
-
den Dunnen JT, Antonarakis SE. Nomenclature for the description of human sequence variations. Hum Genet 2001; 109: 121-124.
-
(2001)
Hum Genet
, vol.109
, pp. 121-124
-
-
den Dunnen, J.T.1
Antonarakis, S.E.2
-
19
-
-
0032568370
-
E-cadherin germline mutations in familial gastric cancer
-
Guilford P, Hopkins J, Harraway J et al. E-cadherin germline mutations in familial gastric cancer. Nature 1998; 392: 402-405.
-
(1998)
Nature
, vol.392
, pp. 402-405
-
-
Guilford, P.1
Hopkins, J.2
Harraway, J.3
-
20
-
-
1842591223
-
Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in an HDGC tumour
-
Oliveira C, de Bruin J, Nabais S et al. Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in an HDGC tumour. Oncogene 2004; 23: 2236-2240.
-
(2004)
Oncogene
, vol.23
, pp. 2236-2240
-
-
Oliveira, C.1
de Bruin, J.2
Nabais, S.3
-
21
-
-
0034816068
-
Altered expression of the fragile histidine triad gene in primary gastric adenocarcinomas
-
Lee SH, Kim WH, Kim HK et al. Altered expression of the fragile histidine triad gene in primary gastric adenocarcinomas. Biochem Biophys Res Commun 2001; 284: 850-855.
-
(2001)
Biochem Biophys Res Commun
, vol.284
, pp. 850-855
-
-
Lee, S.H.1
Kim, W.H.2
Kim, H.K.3
-
22
-
-
6444236850
-
A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus
-
Tao H, Shinmura K, Hanaoka T et al. A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus. Carcinogenesis 2004; 25: 1859-1866.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1859-1866
-
-
Tao, H.1
Shinmura, K.2
Hanaoka, T.3
-
23
-
-
16644382983
-
Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity
-
Shinmura K, Tao H, Yamada H et al. Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity. Hum Mutat 2004; 24: 273-274.
-
(2004)
Hum Mutat
, vol.24
, pp. 273-274
-
-
Shinmura, K.1
Tao, H.2
Yamada, H.3
-
24
-
-
0035476883
-
A nonsense mutation in MLH1 causes exon skipping in three unrelated HNPCC families
-
Stella A, Wagner A, Shito K et al. A nonsense mutation in MLH1 causes exon skipping in three unrelated HNPCC families. Cancer Res 2001; 61: 7020-7024.
-
(2001)
Cancer Res
, vol.61
, pp. 7020-7024
-
-
Stella, A.1
Wagner, A.2
Shito, K.3
-
25
-
-
32944456005
-
Disruption of an exon splicing enhancer in exon 3 of MLH1 is the cause of HNPCC in a Quebec family
-
McVety S, Li L, Gordon PH, Chong G, Foulkes WD. Disruption of an exon splicing enhancer in exon 3 of MLH1 is the cause of HNPCC in a Quebec family. J Med Genet 2006; 43: 153-156.
-
(2006)
J Med Genet
, vol.43
, pp. 153-156
-
-
McVety, S.1
Li, L.2
Gordon, P.H.3
Chong, G.4
Foulkes, W.D.5
-
26
-
-
33644546026
-
Aberrant splicing in MLH1 and MSH2 due to exonic and intronic variants
-
Pagenstecher C, Wehner M, Friedl W et al. Aberrant splicing in MLH1 and MSH2 due to exonic and intronic variants. Hum Genet 2006; 119: 9-22.
-
(2006)
Hum Genet
, vol.119
, pp. 9-22
-
-
Pagenstecher, C.1
Wehner, M.2
Friedl, W.3
-
27
-
-
33749411195
-
In silico and in vivo splicing analysis of MLH1 and MSH2 missense mutations shows exon- and tissue-specific effects
-
Lastella P, Surdo NC, Resta N, Guanti G, Stella A. In silico and in vivo splicing analysis of MLH1 and MSH2 missense mutations shows exon- and tissue-specific effects. BMC Genomics 2006; 7: 243.
-
(2006)
BMC Genomics
, vol.7
, pp. 243
-
-
Lastella, P.1
Surdo, N.C.2
Resta, N.3
Guanti, G.4
Stella, A.5
-
28
-
-
8144219537
-
Familial adenomatous polyposis: aberrant splicing due to missense or silent mutations in the APC gene
-
Aretz S, Uhlhaas S, Sun Y et al. Familial adenomatous polyposis: aberrant splicing due to missense or silent mutations in the APC gene. Hum Mutat 2004; 24: 370-380.
-
(2004)
Hum Mutat
, vol.24
, pp. 370-380
-
-
Aretz, S.1
Uhlhaas, S.2
Sun, Y.3
-
29
-
-
34247629458
-
Alternative splicing and nonsense-mediated mRNA decay in the regulation of a new adenomatous polyposis coli transcript
-
De Rosa M, Morelli G, Cesaro E et al. Alternative splicing and nonsense-mediated mRNA decay in the regulation of a new adenomatous polyposis coli transcript. Gene 2007; 395: 8-14.
-
(2007)
Gene
, vol.395
, pp. 8-14
-
-
De Rosa, M.1
Morelli, G.2
Cesaro, E.3
-
30
-
-
0034901306
-
Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency
-
van Kuilenburg AB, Muller EW, Haasjes J et al. Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency. Clin Cancer Res 2001; 7: 1149-1153.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1149-1153
-
-
van Kuilenburg, A.B.1
Muller, E.W.2
Haasjes, J.3
-
31
-
-
0032534232
-
Altered expression of heterogenous nuclear ribonucleoproteins and SR factors in human colon adenocarcinomas
-
Ghigna C, Moroni M, Porta C, Riva S, Biamonti G. Altered expression of heterogenous nuclear ribonucleoproteins and SR factors in human colon adenocarcinomas. Cancer Res 1998; 58: 5818-5824.
-
(1998)
Cancer Res
, vol.58
, pp. 5818-5824
-
-
Ghigna, C.1
Moroni, M.2
Porta, C.3
Riva, S.4
Biamonti, G.5
-
32
-
-
0036445586
-
CD44 in cancer
-
Naor D, Nedvetzki S, Golan I, Melnik L, Faitelson Y. CD44 in cancer. Crit Rev Clin Lab Sci 2002; 39: 527-579.
-
(2002)
Crit Rev Clin Lab Sci
, vol.39
, pp. 527-579
-
-
Naor, D.1
Nedvetzki, S.2
Golan, I.3
Melnik, L.4
Faitelson, Y.5
-
33
-
-
33344474543
-
Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa
-
Klimek-Tomczak K, Mikula M, Dzwonek A et al. Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa. Br J Cancer 2006; 94: 586-592.
-
(2006)
Br J Cancer
, vol.94
, pp. 586-592
-
-
Klimek-Tomczak, K.1
Mikula, M.2
Dzwonek, A.3
-
34
-
-
51249098983
-
B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival
-
Matos P, Oliveira C, Velho S et al. B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival. Gastroenterology 2008; 135: 899-906.
-
(2008)
Gastroenterology
, vol.135
, pp. 899-906
-
-
Matos, P.1
Oliveira, C.2
Velho, S.3
-
35
-
-
70350782482
-
Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways
-
Gonçalves V, Matos P, Jordan P. Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways. Hum Mol Genet 2009; 18: 3696-3707.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3696-3707
-
-
Gonçalves, V.1
Matos, P.2
Jordan, P.3
-
36
-
-
0030746636
-
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
-
Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 1997; 3: 917-921.
-
(1997)
Nat Med
, vol.3
, pp. 917-921
-
-
Ambrosini, G.1
Adida, C.2
Altieri, D.C.3
-
37
-
-
73449148422
-
cIAP2 as a therapeutic target in colorectal cancer and other malignancies
-
Miura K, Karasawa H, Sasaki I. cIAP2 as a therapeutic target in colorectal cancer and other malignancies. Expert Opin Ther Targets 2009; 13: 1333-1345.
-
(2009)
Expert Opin Ther Targets
, vol.13
, pp. 1333-1345
-
-
Miura, K.1
Karasawa, H.2
Sasaki, I.3
-
38
-
-
0033571983
-
Survivin-deltaEx3 and survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties
-
Mahotka C, Wenzel M, Springer E, Gabbert HE, Gerharz CD. Survivin-deltaEx3 and survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties. Cancer Res 1999; 59: 6097-6102.
-
(1999)
Cancer Res
, vol.59
, pp. 6097-6102
-
-
Mahotka, C.1
Wenzel, M.2
Springer, E.3
Gabbert, H.E.4
Gerharz, C.D.5
-
39
-
-
18344379300
-
Expression of different survivin variants in gastric carcinomas: first clues to a role of survivin-2B in tumour progression
-
Krieg A, Mahotka C, Krieg T et al. Expression of different survivin variants in gastric carcinomas: first clues to a role of survivin-2B in tumour progression. Br J Cancer 2002; 86: 737-743.
-
(2002)
Br J Cancer
, vol.86
, pp. 737-743
-
-
Krieg, A.1
Mahotka, C.2
Krieg, T.3
-
40
-
-
36448944759
-
Alternative splice variants of survivin as potential targets in cancer
-
Sampath J, Pelus LM. Alternative splice variants of survivin as potential targets in cancer. Curr Drug Discov Technol 2007; 4: 174-191.
-
(2007)
Curr Drug Discov Technol
, vol.4
, pp. 174-191
-
-
Sampath, J.1
Pelus, L.M.2
-
41
-
-
34047269793
-
Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells
-
Esufali S, Charames GS, Pethe VV, Buongiorno P, Bapat B. Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells. Cancer Res 2007; 67: 2469-2479.
-
(2007)
Cancer Res
, vol.67
, pp. 2469-2479
-
-
Esufali, S.1
Charames, G.S.2
Pethe, V.V.3
Buongiorno, P.4
Bapat, B.5
-
42
-
-
33744965194
-
Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells
-
Matos P, Jordan P. Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells. J Biol Chem 2006; 281: 13724-13732.
-
(2006)
J Biol Chem
, vol.281
, pp. 13724-13732
-
-
Matos, P.1
Jordan, P.2
-
43
-
-
70450203391
-
The anti-angiogenic isoforms of VEGF in health and disease
-
Qiu Y, Hoareau-Aveilla C, Oltean S, Harper SJ, Bates DO. The anti-angiogenic isoforms of VEGF in health and disease. Biochem Soc Trans 2009; 37: 1207-1213.
-
(2009)
Biochem Soc Trans
, vol.37
, pp. 1207-1213
-
-
Qiu, Y.1
Hoareau-Aveilla, C.2
Oltean, S.3
Harper, S.J.4
Bates, D.O.5
-
44
-
-
54549123309
-
VEGF-A splicing: the key to anti-angiogenic therapeutics?
-
Harper SJ, Bates DO. VEGF-A splicing: the key to anti-angiogenic therapeutics? Nat Rev Cancer 2008; 8: 880-887.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 880-887
-
-
Harper, S.J.1
Bates, D.O.2
-
45
-
-
0033572660
-
Targeted mRNA degradation by double-stranded RNA in vitro
-
Tuschl T, Zamore PD, Lehmann R, Bartel DP, Sharp PA. Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev 1999; 13: 3191-3197.
-
(1999)
Genes Dev
, vol.13
, pp. 3191-3197
-
-
Tuschl, T.1
Zamore, P.D.2
Lehmann, R.3
Bartel, D.P.4
Sharp, P.A.5
-
46
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
47
-
-
34548104659
-
Splicing factor SF3b as a target of the antitumor natural product pladienolide
-
Kotake Y, Sagane K, Owa T et al. Splicing factor SF3b as a target of the antitumor natural product pladienolide. Nat Chem Biol 2007; 3: 570-575.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 570-575
-
-
Kotake, Y.1
Sagane, K.2
Owa, T.3
-
48
-
-
34548095157
-
Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA
-
Kaida D, Motoyoshi H, Tashiro E et al. Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. Nat Chem Biol 2007; 3: 576-583.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 576-583
-
-
Kaida, D.1
Motoyoshi, H.2
Tashiro, E.3
-
49
-
-
2342655502
-
Manipulation of alternative splicing by a newly developed inhibitor of Clks
-
Muraki M, Ohkawara B, Hosoya T et al. Manipulation of alternative splicing by a newly developed inhibitor of Clks. J Biol Chem 2004; 279: 24246-24254.
-
(2004)
J Biol Chem
, vol.279
, pp. 24246-24254
-
-
Muraki, M.1
Ohkawara, B.2
Hosoya, T.3
-
50
-
-
77952029221
-
Deciphering the splicing code
-
Barash Y, Calarco JA, Gao W et al. Deciphering the splicing code. Nature 2010; 465: 53-59.
-
(2010)
Nature
, vol.465
, pp. 53-59
-
-
Barash, Y.1
Calarco, J.A.2
Gao, W.3
|