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Volumn 102, Issue 2, 2011, Pages 309-316

Alternative pre-mRNA splicing in digestive tract malignancy

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; BENZOTHIAZOLE; CD44V ANTIGEN; CD82 ANTIGEN; MESSENGER RNA PRECURSOR; MISMATCH REPAIR PROTEIN; NATURAL PRODUCT; PLADIENOLIDE; PROTEIN; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6; SPLICEOSTATIN A; SURVIVIN; UNCLASSIFIED DRUG; UVOMORULIN; VASCULOTROPIN; VASCULOTROPIN INHIBITOR;

EID: 79952081852     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2010.01797.x     Document Type: Review
Times cited : (32)

References (50)
  • 1
    • 33745899048 scopus 로고    scopus 로고
    • Alternative splicing: new insights from global analyses
    • Blencowe BJ. Alternative splicing: new insights from global analyses. Cell 2006; 126: 37-47.
    • (2006) Cell , vol.126 , pp. 37-47
    • Blencowe, B.J.1
  • 2
    • 7244245762 scopus 로고    scopus 로고
    • Finishing the euchromatic sequence of the human genome
    • International Human Genome Sequencing Consortium. . ; -.
    • International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature 2004; 431: 931-945.
    • (2004) Nature , vol.431 , pp. 931-945
  • 3
    • 0035393343 scopus 로고    scopus 로고
    • Genome-wide detection of alternative splicing in expressed sequences of human genes
    • Modrek B, Resch A, Grasso C, Lee C. Genome-wide detection of alternative splicing in expressed sequences of human genes. Nucleic Acids Res 2001; 29: 2850-2859.
    • (2001) Nucleic Acids Res , vol.29 , pp. 2850-2859
    • Modrek, B.1    Resch, A.2    Grasso, C.3    Lee, C.4
  • 4
    • 0037246718 scopus 로고    scopus 로고
    • ASAP: the Alternative Splicing Annotation Project
    • Lee C, Atanelov L, Modrek B, Xing Y. ASAP: the Alternative Splicing Annotation Project. Nucleic Acids Res 2003; 31: 101-105.
    • (2003) Nucleic Acids Res , vol.31 , pp. 101-105
    • Lee, C.1    Atanelov, L.2    Modrek, B.3    Xing, Y.4
  • 5
    • 0013394889 scopus 로고    scopus 로고
    • Mechanisms of alternative pre-messenger RNA splicing
    • Black DL. Mechanisms of alternative pre-messenger RNA splicing. Annu Rev Biochem 2003; 72: 291-336.
    • (2003) Annu Rev Biochem , vol.72 , pp. 291-336
    • Black, D.L.1
  • 6
    • 57149111212 scopus 로고    scopus 로고
    • Cancer-associated splicing variants of the CDCA1 and MSMB genes expressed in cancer cell lines and surgically resected gastric cancer tissues
    • Ohnuma S, Miura K, Horii A et al. Cancer-associated splicing variants of the CDCA1 and MSMB genes expressed in cancer cell lines and surgically resected gastric cancer tissues. Surgery 2009; 145: 57-68.
    • (2009) Surgery , vol.145 , pp. 57-68
    • Ohnuma, S.1    Miura, K.2    Horii, A.3
  • 7
    • 0001468848 scopus 로고    scopus 로고
    • The RNA World II
    • In: Gesteland RF, Cech TR, Atkins JF, eds. . New York, NY: Cold Spring Harbor Laboratory Press, -.
    • Burge CB, Tuschl T, Sharp PA. Splicing of precursors to mRNAs by the spliceosomes. In: Gesteland RF, Cech TR, Atkins JF, eds. The RNA World II. New York, NY: Cold Spring Harbor Laboratory Press, 1999; 525-560.
    • (1999) Splicing of precursors to mRNAs by the spliceosomes , pp. 525-560
    • Burge, C.B.1    Tuschl, T.2    Sharp, P.A.3
  • 8
    • 60349104299 scopus 로고    scopus 로고
    • The spliceosome: design principles of a dynamic RNP machine
    • Wahl MC, Will CL, Lührmann R. The spliceosome: design principles of a dynamic RNP machine. Cell 2009; 136: 701-718.
    • (2009) Cell , vol.136 , pp. 701-718
    • Wahl, M.C.1    Will, C.L.2    Lührmann, R.3
  • 9
    • 70350569286 scopus 로고    scopus 로고
    • Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches
    • Chen M, Manley JL. Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches. Nat Rev Mol Cell Biol 2009; 10: 741-754.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 741-754
    • Chen, M.1    Manley, J.L.2
  • 10
    • 0033153348 scopus 로고    scopus 로고
    • hnRNP complexes: composition, structure, and function
    • Krecic AM, Swanson MS. hnRNP complexes: composition, structure, and function. Curr Opin Cell Biol 1999; 11: 363-371.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 363-371
    • Krecic, A.M.1    Swanson, M.S.2
  • 12
    • 0027160003 scopus 로고
    • Distinct functions of SR proteins in alternative pre-mRNA splicing
    • Zahler AM, Neugebauer KM, Lane WS, Roth MB. Distinct functions of SR proteins in alternative pre-mRNA splicing. Science 1993; 260: 219-222.
    • (1993) Science , vol.260 , pp. 219-222
    • Zahler, A.M.1    Neugebauer, K.M.2    Lane, W.S.3    Roth, M.B.4
  • 13
    • 0036534129 scopus 로고    scopus 로고
    • Alternative splicing: multiple control mechanisms and involvement in human disease
    • Cáceres JF, Kornblihtt AR. Alternative splicing: multiple control mechanisms and involvement in human disease. Trends Genet 2002; 18: 186-193.
    • (2002) Trends Genet , vol.18 , pp. 186-193
    • Cáceres, J.F.1    Kornblihtt, A.R.2
  • 14
    • 61649087689 scopus 로고    scopus 로고
    • ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing
    • Warzecha CC, Sato TK, Nabet B, Hogenesch JB, Carstens RP. ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Mol Cell 2009; 33: 591-601.
    • (2009) Mol Cell , vol.33 , pp. 591-601
    • Warzecha, C.C.1    Sato, T.K.2    Nabet, B.3    Hogenesch, J.B.4    Carstens, R.P.5
  • 15
    • 26944489645 scopus 로고    scopus 로고
    • Building specificity with nonspecific RNA-binding proteins
    • Singh R, Valcárcel J. Building specificity with nonspecific RNA-binding proteins. Nat Struct Mol Biol 2005; 12: 645-653.
    • (2005) Nat Struct Mol Biol , vol.12 , pp. 645-653
    • Singh, R.1    Valcárcel, J.2
  • 16
    • 48149095822 scopus 로고    scopus 로고
    • Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense?
    • McGlincy NJ, Smith CW. Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense? Trends Biochem Sci 2008; 33: 385-393.
    • (2008) Trends Biochem Sci , vol.33 , pp. 385-393
    • McGlincy, N.J.1    Smith, C.W.2
  • 18
    • 0034908554 scopus 로고    scopus 로고
    • Nomenclature for the description of human sequence variations
    • den Dunnen JT, Antonarakis SE. Nomenclature for the description of human sequence variations. Hum Genet 2001; 109: 121-124.
    • (2001) Hum Genet , vol.109 , pp. 121-124
    • den Dunnen, J.T.1    Antonarakis, S.E.2
  • 19
    • 0032568370 scopus 로고    scopus 로고
    • E-cadherin germline mutations in familial gastric cancer
    • Guilford P, Hopkins J, Harraway J et al. E-cadherin germline mutations in familial gastric cancer. Nature 1998; 392: 402-405.
    • (1998) Nature , vol.392 , pp. 402-405
    • Guilford, P.1    Hopkins, J.2    Harraway, J.3
  • 20
    • 1842591223 scopus 로고    scopus 로고
    • Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in an HDGC tumour
    • Oliveira C, de Bruin J, Nabais S et al. Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in an HDGC tumour. Oncogene 2004; 23: 2236-2240.
    • (2004) Oncogene , vol.23 , pp. 2236-2240
    • Oliveira, C.1    de Bruin, J.2    Nabais, S.3
  • 21
    • 0034816068 scopus 로고    scopus 로고
    • Altered expression of the fragile histidine triad gene in primary gastric adenocarcinomas
    • Lee SH, Kim WH, Kim HK et al. Altered expression of the fragile histidine triad gene in primary gastric adenocarcinomas. Biochem Biophys Res Commun 2001; 284: 850-855.
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 850-855
    • Lee, S.H.1    Kim, W.H.2    Kim, H.K.3
  • 22
    • 6444236850 scopus 로고    scopus 로고
    • A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus
    • Tao H, Shinmura K, Hanaoka T et al. A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus. Carcinogenesis 2004; 25: 1859-1866.
    • (2004) Carcinogenesis , vol.25 , pp. 1859-1866
    • Tao, H.1    Shinmura, K.2    Hanaoka, T.3
  • 23
    • 16644382983 scopus 로고    scopus 로고
    • Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity
    • Shinmura K, Tao H, Yamada H et al. Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity. Hum Mutat 2004; 24: 273-274.
    • (2004) Hum Mutat , vol.24 , pp. 273-274
    • Shinmura, K.1    Tao, H.2    Yamada, H.3
  • 24
    • 0035476883 scopus 로고    scopus 로고
    • A nonsense mutation in MLH1 causes exon skipping in three unrelated HNPCC families
    • Stella A, Wagner A, Shito K et al. A nonsense mutation in MLH1 causes exon skipping in three unrelated HNPCC families. Cancer Res 2001; 61: 7020-7024.
    • (2001) Cancer Res , vol.61 , pp. 7020-7024
    • Stella, A.1    Wagner, A.2    Shito, K.3
  • 25
    • 32944456005 scopus 로고    scopus 로고
    • Disruption of an exon splicing enhancer in exon 3 of MLH1 is the cause of HNPCC in a Quebec family
    • McVety S, Li L, Gordon PH, Chong G, Foulkes WD. Disruption of an exon splicing enhancer in exon 3 of MLH1 is the cause of HNPCC in a Quebec family. J Med Genet 2006; 43: 153-156.
    • (2006) J Med Genet , vol.43 , pp. 153-156
    • McVety, S.1    Li, L.2    Gordon, P.H.3    Chong, G.4    Foulkes, W.D.5
  • 26
    • 33644546026 scopus 로고    scopus 로고
    • Aberrant splicing in MLH1 and MSH2 due to exonic and intronic variants
    • Pagenstecher C, Wehner M, Friedl W et al. Aberrant splicing in MLH1 and MSH2 due to exonic and intronic variants. Hum Genet 2006; 119: 9-22.
    • (2006) Hum Genet , vol.119 , pp. 9-22
    • Pagenstecher, C.1    Wehner, M.2    Friedl, W.3
  • 27
    • 33749411195 scopus 로고    scopus 로고
    • In silico and in vivo splicing analysis of MLH1 and MSH2 missense mutations shows exon- and tissue-specific effects
    • Lastella P, Surdo NC, Resta N, Guanti G, Stella A. In silico and in vivo splicing analysis of MLH1 and MSH2 missense mutations shows exon- and tissue-specific effects. BMC Genomics 2006; 7: 243.
    • (2006) BMC Genomics , vol.7 , pp. 243
    • Lastella, P.1    Surdo, N.C.2    Resta, N.3    Guanti, G.4    Stella, A.5
  • 28
    • 8144219537 scopus 로고    scopus 로고
    • Familial adenomatous polyposis: aberrant splicing due to missense or silent mutations in the APC gene
    • Aretz S, Uhlhaas S, Sun Y et al. Familial adenomatous polyposis: aberrant splicing due to missense or silent mutations in the APC gene. Hum Mutat 2004; 24: 370-380.
    • (2004) Hum Mutat , vol.24 , pp. 370-380
    • Aretz, S.1    Uhlhaas, S.2    Sun, Y.3
  • 29
    • 34247629458 scopus 로고    scopus 로고
    • Alternative splicing and nonsense-mediated mRNA decay in the regulation of a new adenomatous polyposis coli transcript
    • De Rosa M, Morelli G, Cesaro E et al. Alternative splicing and nonsense-mediated mRNA decay in the regulation of a new adenomatous polyposis coli transcript. Gene 2007; 395: 8-14.
    • (2007) Gene , vol.395 , pp. 8-14
    • De Rosa, M.1    Morelli, G.2    Cesaro, E.3
  • 30
    • 0034901306 scopus 로고    scopus 로고
    • Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency
    • van Kuilenburg AB, Muller EW, Haasjes J et al. Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency. Clin Cancer Res 2001; 7: 1149-1153.
    • (2001) Clin Cancer Res , vol.7 , pp. 1149-1153
    • van Kuilenburg, A.B.1    Muller, E.W.2    Haasjes, J.3
  • 31
    • 0032534232 scopus 로고    scopus 로고
    • Altered expression of heterogenous nuclear ribonucleoproteins and SR factors in human colon adenocarcinomas
    • Ghigna C, Moroni M, Porta C, Riva S, Biamonti G. Altered expression of heterogenous nuclear ribonucleoproteins and SR factors in human colon adenocarcinomas. Cancer Res 1998; 58: 5818-5824.
    • (1998) Cancer Res , vol.58 , pp. 5818-5824
    • Ghigna, C.1    Moroni, M.2    Porta, C.3    Riva, S.4    Biamonti, G.5
  • 33
    • 33344474543 scopus 로고    scopus 로고
    • Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa
    • Klimek-Tomczak K, Mikula M, Dzwonek A et al. Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa. Br J Cancer 2006; 94: 586-592.
    • (2006) Br J Cancer , vol.94 , pp. 586-592
    • Klimek-Tomczak, K.1    Mikula, M.2    Dzwonek, A.3
  • 34
    • 51249098983 scopus 로고    scopus 로고
    • B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival
    • Matos P, Oliveira C, Velho S et al. B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival. Gastroenterology 2008; 135: 899-906.
    • (2008) Gastroenterology , vol.135 , pp. 899-906
    • Matos, P.1    Oliveira, C.2    Velho, S.3
  • 35
    • 70350782482 scopus 로고    scopus 로고
    • Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways
    • Gonçalves V, Matos P, Jordan P. Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways. Hum Mol Genet 2009; 18: 3696-3707.
    • (2009) Hum Mol Genet , vol.18 , pp. 3696-3707
    • Gonçalves, V.1    Matos, P.2    Jordan, P.3
  • 36
    • 0030746636 scopus 로고    scopus 로고
    • A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
    • Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 1997; 3: 917-921.
    • (1997) Nat Med , vol.3 , pp. 917-921
    • Ambrosini, G.1    Adida, C.2    Altieri, D.C.3
  • 37
    • 73449148422 scopus 로고    scopus 로고
    • cIAP2 as a therapeutic target in colorectal cancer and other malignancies
    • Miura K, Karasawa H, Sasaki I. cIAP2 as a therapeutic target in colorectal cancer and other malignancies. Expert Opin Ther Targets 2009; 13: 1333-1345.
    • (2009) Expert Opin Ther Targets , vol.13 , pp. 1333-1345
    • Miura, K.1    Karasawa, H.2    Sasaki, I.3
  • 38
    • 0033571983 scopus 로고    scopus 로고
    • Survivin-deltaEx3 and survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties
    • Mahotka C, Wenzel M, Springer E, Gabbert HE, Gerharz CD. Survivin-deltaEx3 and survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties. Cancer Res 1999; 59: 6097-6102.
    • (1999) Cancer Res , vol.59 , pp. 6097-6102
    • Mahotka, C.1    Wenzel, M.2    Springer, E.3    Gabbert, H.E.4    Gerharz, C.D.5
  • 39
    • 18344379300 scopus 로고    scopus 로고
    • Expression of different survivin variants in gastric carcinomas: first clues to a role of survivin-2B in tumour progression
    • Krieg A, Mahotka C, Krieg T et al. Expression of different survivin variants in gastric carcinomas: first clues to a role of survivin-2B in tumour progression. Br J Cancer 2002; 86: 737-743.
    • (2002) Br J Cancer , vol.86 , pp. 737-743
    • Krieg, A.1    Mahotka, C.2    Krieg, T.3
  • 40
    • 36448944759 scopus 로고    scopus 로고
    • Alternative splice variants of survivin as potential targets in cancer
    • Sampath J, Pelus LM. Alternative splice variants of survivin as potential targets in cancer. Curr Drug Discov Technol 2007; 4: 174-191.
    • (2007) Curr Drug Discov Technol , vol.4 , pp. 174-191
    • Sampath, J.1    Pelus, L.M.2
  • 41
    • 34047269793 scopus 로고    scopus 로고
    • Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells
    • Esufali S, Charames GS, Pethe VV, Buongiorno P, Bapat B. Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells. Cancer Res 2007; 67: 2469-2479.
    • (2007) Cancer Res , vol.67 , pp. 2469-2479
    • Esufali, S.1    Charames, G.S.2    Pethe, V.V.3    Buongiorno, P.4    Bapat, B.5
  • 42
    • 33744965194 scopus 로고    scopus 로고
    • Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells
    • Matos P, Jordan P. Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells. J Biol Chem 2006; 281: 13724-13732.
    • (2006) J Biol Chem , vol.281 , pp. 13724-13732
    • Matos, P.1    Jordan, P.2
  • 44
    • 54549123309 scopus 로고    scopus 로고
    • VEGF-A splicing: the key to anti-angiogenic therapeutics?
    • Harper SJ, Bates DO. VEGF-A splicing: the key to anti-angiogenic therapeutics? Nat Rev Cancer 2008; 8: 880-887.
    • (2008) Nat Rev Cancer , vol.8 , pp. 880-887
    • Harper, S.J.1    Bates, D.O.2
  • 46
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 47
    • 34548104659 scopus 로고    scopus 로고
    • Splicing factor SF3b as a target of the antitumor natural product pladienolide
    • Kotake Y, Sagane K, Owa T et al. Splicing factor SF3b as a target of the antitumor natural product pladienolide. Nat Chem Biol 2007; 3: 570-575.
    • (2007) Nat Chem Biol , vol.3 , pp. 570-575
    • Kotake, Y.1    Sagane, K.2    Owa, T.3
  • 48
    • 34548095157 scopus 로고    scopus 로고
    • Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA
    • Kaida D, Motoyoshi H, Tashiro E et al. Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. Nat Chem Biol 2007; 3: 576-583.
    • (2007) Nat Chem Biol , vol.3 , pp. 576-583
    • Kaida, D.1    Motoyoshi, H.2    Tashiro, E.3
  • 49
    • 2342655502 scopus 로고    scopus 로고
    • Manipulation of alternative splicing by a newly developed inhibitor of Clks
    • Muraki M, Ohkawara B, Hosoya T et al. Manipulation of alternative splicing by a newly developed inhibitor of Clks. J Biol Chem 2004; 279: 24246-24254.
    • (2004) J Biol Chem , vol.279 , pp. 24246-24254
    • Muraki, M.1    Ohkawara, B.2    Hosoya, T.3
  • 50
    • 77952029221 scopus 로고    scopus 로고
    • Deciphering the splicing code
    • Barash Y, Calarco JA, Gao W et al. Deciphering the splicing code. Nature 2010; 465: 53-59.
    • (2010) Nature , vol.465 , pp. 53-59
    • Barash, Y.1    Calarco, J.A.2    Gao, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.