In silico and in vivo splicing analysis of MLH1 and MSH2 missense mutations shows exon- and tissue-specific effects

BMC Genomics

Volumn 7, Issue , 2006, Pages

  Lastella, Patrizia ^a,b   Surdo, Nicoletta Concetta ^a,b   Resta, Nicoletta ^a,b   Guanti, Ginevra ^a,b   Stella, Alessandro ^a,b  

^a UNIVERSITY OF BARI   (Italy)

^b POLICLINICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN MLH1; PROTEIN MSH2; RNA;

ALTERNATIVE RNA SPLICING; ARTICLE; CANCER RISK; CELL LINE; CELL SPECIFICITY; COMPUTER ANALYSIS; COMPUTER MODEL; CONTROLLED STUDY; CORRELATION ANALYSIS; EXON; FAMILIAL CANCER; GENE EXPRESSION REGULATION; GENE LOCATION; GENETIC ALGORITHM; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; GENETIC TRANSFECTION; HUMAN; IN VIVO STUDY; MISSENSE MUTATION; MUTAGENESIS; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PHENOTYPIC VARIATION; PLASMID; PREDICTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; TISSUE SPECIFICITY; WILD TYPE;

EID: 33749411195     PISSN: 14712164     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-7-243     Document Type: Article

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