메뉴 건너뛰기




Volumn 50, Issue 4, 2011, Pages 606-612

Uncoupling between enhanced excitation-contraction coupling and the response to heart disease: Lessons from the PI3Kγ knockout murine model

Author keywords

Cardiomyopathy; Cell adhesion; Excitation contraction coupling; Mechanotransduction; Signaling

Indexed keywords

CALCIUM ION; CYCLIC AMP; MATRIX METALLOPROTEINASE; NERVE CELL ADHESION MOLECULE; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA;

EID: 79952073678     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2011.01.011     Document Type: Review
Times cited : (8)

References (90)
  • 1
    • 39749168495 scopus 로고    scopus 로고
    • Tackling heart failure in the twenty-first century
    • Mudd J.O., Kass D.A. Tackling heart failure in the twenty-first century. Nature 2008 Feb 21, 451(7181):919-928.
    • (2008) Nature , vol.451 , Issue.7181 , pp. 919-928
    • Mudd, J.O.1    Kass, D.A.2
  • 2
    • 41449086790 scopus 로고    scopus 로고
    • Cardiac plasticity
    • Hill J.A., Olson E.N. Cardiac plasticity. N Engl J Med 2008 Mar 27, 358(13):1370-1380.
    • (2008) N Engl J Med , vol.358 , Issue.13 , pp. 1370-1380
    • Hill, J.A.1    Olson, E.N.2
  • 3
    • 77956354653 scopus 로고    scopus 로고
    • Cell communications in the heart
    • Tirziu D., Giordano F.J., Simons M. Cell communications in the heart. Circulation 2010 Aug 31, 122(9):928-937.
    • (2010) Circulation , vol.122 , Issue.9 , pp. 928-937
    • Tirziu, D.1    Giordano, F.J.2    Simons, M.3
  • 4
    • 0030969371 scopus 로고    scopus 로고
    • The cellular and molecular response of cardiac myocytes to mechanical stress
    • Sadoshima J., Izumo S. The cellular and molecular response of cardiac myocytes to mechanical stress. Annu Rev Physiol 1997, 59:551-571.
    • (1997) Annu Rev Physiol , vol.59 , pp. 551-571
    • Sadoshima, J.1    Izumo, S.2
  • 5
    • 2942751868 scopus 로고    scopus 로고
    • Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II
    • Zou Y., Akazawa H., Qin Y., Sano M., Takano H., Minamino T., et al. Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nat Cell Biol 2004 Jun, 6(6):499-506.
    • (2004) Nat Cell Biol , vol.6 , Issue.6 , pp. 499-506
    • Zou, Y.1    Akazawa, H.2    Qin, Y.3    Sano, M.4    Takano, H.5    Minamino, T.6
  • 6
    • 0037049977 scopus 로고    scopus 로고
    • Cardiac excitation-contraction coupling
    • Bers D.M. Cardiac excitation-contraction coupling. Nature 2002 Jan 10, 415(6868):198-205.
    • (2002) Nature , vol.415 , Issue.6868 , pp. 198-205
    • Bers, D.M.1
  • 7
    • 49849099122 scopus 로고    scopus 로고
    • Structural coupling of cardiomyocytes and noncardiomyocytes: quantitative comparisons using a novel micropatterned cell pair assay
    • Pedrotty D.M., Klinger R.Y., Badie N., Hinds S., Kardashian A., Bursac N. Structural coupling of cardiomyocytes and noncardiomyocytes: quantitative comparisons using a novel micropatterned cell pair assay. Am J Physiol Heart Circ Physiol 2008 Jul, 295(1):H390-H400.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295 , Issue.1
    • Pedrotty, D.M.1    Klinger, R.Y.2    Badie, N.3    Hinds, S.4    Kardashian, A.5    Bursac, N.6
  • 8
    • 0038190993 scopus 로고    scopus 로고
    • Costameres: the Achilles' heel of Herculean muscle
    • Ervasti J.M. Costameres: the Achilles' heel of Herculean muscle. J Biol Chem 2003 Apr 18, 278(16):13591-13594.
    • (2003) J Biol Chem , vol.278 , Issue.16 , pp. 13591-13594
    • Ervasti, J.M.1
  • 10
    • 0033712289 scopus 로고    scopus 로고
    • N-Cadherin: structure, function and importance in the formation of new intercalated disc-like cell contacts in cardiomyocytes
    • Zuppinger C., Eppenberger-Eberhardt M., Eppenberger H.M. N-Cadherin: structure, function and importance in the formation of new intercalated disc-like cell contacts in cardiomyocytes. Heart Fail Rev 2000 Oct, 5(3):251-257.
    • (2000) Heart Fail Rev , Issue.3 , pp. 251-257
    • Zuppinger, C.1    Eppenberger-Eberhardt, M.2    Eppenberger, H.M.3
  • 11
    • 9644289331 scopus 로고    scopus 로고
    • N-cadherin-mediated cell adhesion determines the plasticity for cell alignment in response to mechanical stretch in cultured cardiomyocytes
    • Matsuda T., Takahashi K., Nariai T., Ito T., Takatani T., Fujio Y., et al. N-cadherin-mediated cell adhesion determines the plasticity for cell alignment in response to mechanical stretch in cultured cardiomyocytes. Biochem Biophys Res Commun 2005 Jan 7, 326(1):228-232.
    • (2005) Biochem Biophys Res Commun , vol.326 , Issue.1 , pp. 228-232
    • Matsuda, T.1    Takahashi, K.2    Nariai, T.3    Ito, T.4    Takatani, T.5    Fujio, Y.6
  • 12
    • 35548987124 scopus 로고    scopus 로고
    • Desmosomes from a structural perspective
    • Stokes D.L. Desmosomes from a structural perspective. Curr Opin Cell Biol 2007 Oct, 19(5):565-571.
    • (2007) Curr Opin Cell Biol , vol.19 , Issue.5 , pp. 565-571
    • Stokes, D.L.1
  • 13
    • 0037031828 scopus 로고    scopus 로고
    • Signal transduction from N-cadherin increases Bcl-2. Regulation of the phosphatidylinositol 3-kinase/Akt pathway by homophilic adhesion and actin cytoskeletal organization
    • Tran N.L., Adams D.G., Vaillancourt R.R., Heimark R.L. Signal transduction from N-cadherin increases Bcl-2. Regulation of the phosphatidylinositol 3-kinase/Akt pathway by homophilic adhesion and actin cytoskeletal organization. J Biol Chem 2002 Sep 6, 277(36):32905-32914.
    • (2002) J Biol Chem , vol.277 , Issue.36 , pp. 32905-32914
    • Tran, N.L.1    Adams, D.G.2    Vaillancourt, R.R.3    Heimark, R.L.4
  • 14
    • 0037040925 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase controls human intestinal epithelial cell differentiation by promoting adherens junction assembly and p38 MAPK activation
    • Laprise P., Chailler P., Houde M., Beaulieu J.F., Boucher M.J., Rivard N. Phosphatidylinositol 3-kinase controls human intestinal epithelial cell differentiation by promoting adherens junction assembly and p38 MAPK activation. J Biol Chem 2002 Mar 8, 277(10):8226-8234.
    • (2002) J Biol Chem , vol.277 , Issue.10 , pp. 8226-8234
    • Laprise, P.1    Chailler, P.2    Houde, M.3    Beaulieu, J.F.4    Boucher, M.J.5    Rivard, N.6
  • 15
    • 0032871262 scopus 로고    scopus 로고
    • Differential responses of adult cardiac fibroblasts to in vitro biaxial strain patterns
    • Lee A.A., Delhaas T., McCulloch A.D., Villarreal F.J. Differential responses of adult cardiac fibroblasts to in vitro biaxial strain patterns. J Mol Cell Cardiol 1999 Oct, 31(10):1833-1843.
    • (1999) J Mol Cell Cardiol , vol.31 , Issue.10 , pp. 1833-1843
    • Lee, A.A.1    Delhaas, T.2    McCulloch, A.D.3    Villarreal, F.J.4
  • 16
    • 0033550149 scopus 로고    scopus 로고
    • Regulation of cardiac myocyte protein turnover and myofibrillar structure in vitro by specific directions of stretch
    • Simpson D.G., Majeski M., Borg T.K., Terracio L. Regulation of cardiac myocyte protein turnover and myofibrillar structure in vitro by specific directions of stretch. Circ Res 1999 Nov 12, 85(10):e59-e69.
    • (1999) Circ Res , vol.85 , Issue.10
    • Simpson, D.G.1    Majeski, M.2    Borg, T.K.3    Terracio, L.4
  • 17
    • 0037112402 scopus 로고    scopus 로고
    • Dance band on the Titanic: biomechanical signaling in cardiac hypertrophy
    • Sussman M.A., McCulloch A., Borg T.K. Dance band on the Titanic: biomechanical signaling in cardiac hypertrophy. Circ Res 2002 Nov 15, 91(10):888-898.
    • (2002) Circ Res , vol.91 , Issue.10 , pp. 888-898
    • Sussman, M.A.1    McCulloch, A.2    Borg, T.K.3
  • 18
    • 13844253989 scopus 로고    scopus 로고
    • Myocardial extra-cellular matrix and its regulation by metalloproteinases and their inhibitors
    • Kassiri Z., Khokha R. Myocardial extra-cellular matrix and its regulation by metalloproteinases and their inhibitors. Thromb Haemost 2005 Feb, 93(2):212-219.
    • (2005) Thromb Haemost , vol.93 , Issue.2 , pp. 212-219
    • Kassiri, Z.1    Khokha, R.2
  • 19
    • 35848961683 scopus 로고    scopus 로고
    • Cell-matrix adhesion
    • Berrier A.L., Yamada K.M. Cell-matrix adhesion. J Cell Physiol 2007 Dec, 213(3):565-573.
    • (2007) J Cell Physiol , vol.213 , Issue.3 , pp. 565-573
    • Berrier, A.L.1    Yamada, K.M.2
  • 21
    • 0034077226 scopus 로고    scopus 로고
    • Rapid gene transcription induced by stretch in cardiac myocytes and fibroblasts and their paracrine influence on stationary myocytes and fibroblasts
    • van Wamel J.E., Ruwhof C., van der Valk-Kokshoorn E.J., Schrier P.I., van der Laarse A. Rapid gene transcription induced by stretch in cardiac myocytes and fibroblasts and their paracrine influence on stationary myocytes and fibroblasts. Pflugers Arch 2000 Apr, 439(6):781-788.
    • (2000) Pflugers Arch , vol.439 , Issue.6 , pp. 781-788
    • van Wamel, J.E.1    Ruwhof, C.2    van der Valk-Kokshoorn, E.J.3    Schrier, P.I.4    van der Laarse, A.5
  • 22
    • 20444465227 scopus 로고    scopus 로고
    • Integrin activation and matrix binding mediate cellular responses to mechanical stretch
    • Katsumi A., Naoe T., Matsushita T., Kaibuchi K., Schwartz M.A. Integrin activation and matrix binding mediate cellular responses to mechanical stretch. J Biol Chem 2005 Apr 29, 280(17):16546-16549.
    • (2005) J Biol Chem , vol.280 , Issue.17 , pp. 16546-16549
    • Katsumi, A.1    Naoe, T.2    Matsushita, T.3    Kaibuchi, K.4    Schwartz, M.A.5
  • 23
    • 0034123657 scopus 로고    scopus 로고
    • Mechanical stress-induced cardiac hypertrophy: mechanisms and signal transduction pathways
    • Ruwhof C., van der Laarse A. Mechanical stress-induced cardiac hypertrophy: mechanisms and signal transduction pathways. Cardiovasc Res 2000 Jul, 47(1):23-37.
    • (2000) Cardiovasc Res , vol.47 , Issue.1 , pp. 23-37
    • Ruwhof, C.1    van der Laarse, A.2
  • 24
    • 0034038922 scopus 로고    scopus 로고
    • Role of mechanical factors in modulating cardiac fibroblast function and extracellular matrix synthesis
    • MacKenna D., Summerour S.R., Villarreal F.J. Role of mechanical factors in modulating cardiac fibroblast function and extracellular matrix synthesis. Cardiovasc Res 2000 May, 46(2):257-263.
    • (2000) Cardiovasc Res , vol.46 , Issue.2 , pp. 257-263
    • MacKenna, D.1    Summerour, S.R.2    Villarreal, F.J.3
  • 25
    • 33748278519 scopus 로고    scopus 로고
    • Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure
    • White D.E., Coutu P., Shi Y.F., Tardif J.C., Nattel S., St Arnaud R., et al. Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure. Genes Dev 2006 Sep 1, 20(17):2355-2360.
    • (2006) Genes Dev , vol.20 , Issue.17 , pp. 2355-2360
    • White, D.E.1    Coutu, P.2    Shi, Y.F.3    Tardif, J.C.4    Nattel, S.5    St Arnaud, R.6
  • 26
    • 33751226584 scopus 로고    scopus 로고
    • Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice
    • Lu H., Fedak P.W., Dai X., Du C., Zhou Y.Q., Henkelman M., et al. Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice. Circulation 2006 Nov 21, 114(21):2271-2279.
    • (2006) Circulation , vol.114 , Issue.21 , pp. 2271-2279
    • Lu, H.1    Fedak, P.W.2    Dai, X.3    Du, C.4    Zhou, Y.Q.5    Henkelman, M.6
  • 27
    • 44349136151 scopus 로고    scopus 로고
    • Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice
    • Peng X., Wu X., Druso J.E., Wei H., Park A.Y., Kraus M.S., et al. Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice. Proc Natl Acad Sci USA 2008 May 6, 105(18):6638-6643.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.18 , pp. 6638-6643
    • Peng, X.1    Wu, X.2    Druso, J.E.3    Wei, H.4    Park, A.Y.5    Kraus, M.S.6
  • 28
    • 0032525330 scopus 로고    scopus 로고
    • Beta1 integrins participate in the hypertrophic response of rat ventricular myocytes
    • Ross R.S., Pham C., Shai S.Y., Goldhaber J.I., Fenczik C., Glembotski C.C., et al. Beta1 integrins participate in the hypertrophic response of rat ventricular myocytes. Circ Res 1998 Jun 15, 82(11):1160-1172.
    • (1998) Circ Res , vol.82 , Issue.11 , pp. 1160-1172
    • Ross, R.S.1    Pham, C.2    Shai, S.Y.3    Goldhaber, J.I.4    Fenczik, C.5    Glembotski, C.C.6
  • 29
    • 0027938974 scopus 로고
    • Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase
    • Chen H.C., Guan J.L. Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase. Proc Natl Acad Sci USA 1994 Oct 11, 91(21):10148-10152.
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.21 , pp. 10148-10152
    • Chen, H.C.1    Guan, J.L.2
  • 30
    • 34249798185 scopus 로고    scopus 로고
    • FAK association with multiple signal proteins mediates pressure-induced colon cancer cell adhesion via a Src-dependent PI3K/Akt pathway
    • Thamilselvan V., Craig D.H., Basson M.D. FAK association with multiple signal proteins mediates pressure-induced colon cancer cell adhesion via a Src-dependent PI3K/Akt pathway. FASEB J 2007 Jun, 21(8):1730-1741.
    • (2007) FASEB J , vol.21 , Issue.8 , pp. 1730-1741
    • Thamilselvan, V.1    Craig, D.H.2    Basson, M.D.3
  • 32
    • 62349105876 scopus 로고    scopus 로고
    • Cardiac regulation by phosphoinositide 3-kinases and PTEN
    • Oudit G.Y., Penninger J.M. Cardiac regulation by phosphoinositide 3-kinases and PTEN. Cardiovasc Res 2009 May 1, 82(2):250-260.
    • (2009) Cardiovasc Res , vol.82 , Issue.2 , pp. 250-260
    • Oudit, G.Y.1    Penninger, J.M.2
  • 33
    • 0041336899 scopus 로고    scopus 로고
    • Phosphatases in cell-matrix adhesion and migration
    • Larsen M., Tremblay M.L., Yamada K.M. Phosphatases in cell-matrix adhesion and migration. Nat Rev Mol Cell Biol 2003 Sep, 4(9):700-711.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , Issue.9 , pp. 700-711
    • Larsen, M.1    Tremblay, M.L.2    Yamada, K.M.3
  • 34
    • 0032530482 scopus 로고    scopus 로고
    • Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase
    • Delcommenne M., Tan C., Gray V., Rue L., Woodgett J., Dedhar S. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase. Proc Natl Acad Sci USA 1998 Sep 15, 95(19):11211-11216.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.19 , pp. 11211-11216
    • Delcommenne, M.1    Tan, C.2    Gray, V.3    Rue, L.4    Woodgett, J.5    Dedhar, S.6
  • 35
    • 0032746701 scopus 로고    scopus 로고
    • Cell-extracellular matrix interactions stimulate the AP-1 transcription factor in an integrin-linked kinase- and glycogen synthase kinase 3-dependent manner
    • Troussard A.A., Tan C., Yoganathan T.N., Dedhar S. Cell-extracellular matrix interactions stimulate the AP-1 transcription factor in an integrin-linked kinase- and glycogen synthase kinase 3-dependent manner. Mol Cell Biol 1999 Nov, 19(11):7420-7427.
    • (1999) Mol Cell Biol , vol.19 , Issue.11 , pp. 7420-7427
    • Troussard, A.A.1    Tan, C.2    Yoganathan, T.N.3    Dedhar, S.4
  • 37
    • 35648949369 scopus 로고    scopus 로고
    • Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy
    • Zemljic-Harpf A.E., Miller J.C., Henderson S.A., Wright A.T., Manso A.M., Elsherif L., et al. Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy. Mol Cell Biol 2007 Nov, 27(21):7522-7537.
    • (2007) Mol Cell Biol , vol.27 , Issue.21 , pp. 7522-7537
    • Zemljic-Harpf, A.E.1    Miller, J.C.2    Henderson, S.A.3    Wright, A.T.4    Manso, A.M.5    Elsherif, L.6
  • 38
    • 0347915657 scopus 로고    scopus 로고
    • Loss of dystrophin causes aberrant mechanotransduction in skeletal muscle fibers
    • Kumar A., Khandelwal N., Malya R., Reid M.B., Boriek A.M. Loss of dystrophin causes aberrant mechanotransduction in skeletal muscle fibers. FASEB J 2004 Jan, 18(1):102-113.
    • (2004) FASEB J , vol.18 , Issue.1 , pp. 102-113
    • Kumar, A.1    Khandelwal, N.2    Malya, R.3    Reid, M.B.4    Boriek, A.M.5
  • 39
  • 40
    • 0037236642 scopus 로고    scopus 로고
    • Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload
    • Brancaccio M., Fratta L., Notte A., Hirsch E., Poulet R., Guazzone S., et al. Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload. Nat Med 2003 Jan, 9(1):68-75.
    • (2003) Nat Med , vol.9 , Issue.1 , pp. 68-75
    • Brancaccio, M.1    Fratta, L.2    Notte, A.3    Hirsch, E.4    Poulet, R.5    Guazzone, S.6
  • 41
    • 20344399430 scopus 로고    scopus 로고
    • Cardiac overexpression of melusin protects from dilated cardiomyopathy due to long-standing pressure overload
    • De Acetis M., Notte A., Accornero F., Selvetella G., Brancaccio M., Vecchione C., et al. Cardiac overexpression of melusin protects from dilated cardiomyopathy due to long-standing pressure overload. Circ Res 2005 May 27, 96(10):1087-1094.
    • (2005) Circ Res , vol.96 , Issue.10 , pp. 1087-1094
    • De Acetis, M.1    Notte, A.2    Accornero, F.3    Selvetella, G.4    Brancaccio, M.5    Vecchione, C.6
  • 42
    • 34248363982 scopus 로고    scopus 로고
    • Beta-catenin downregulation is required for adaptive cardiac remodeling
    • Baurand A., Zelarayan L., Betney R., Gehrke C., Dunger S., Noack C., et al. Beta-catenin downregulation is required for adaptive cardiac remodeling. Circ Res 2007 May 11, 100(9):1353-1362.
    • (2007) Circ Res , vol.100 , Issue.9 , pp. 1353-1362
    • Baurand, A.1    Zelarayan, L.2    Betney, R.3    Gehrke, C.4    Dunger, S.5    Noack, C.6
  • 43
    • 48749127844 scopus 로고    scopus 로고
    • Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart
    • Lim B.K., Xiong D., Dorner A., Youn T.J., Yung A., Liu T.I., et al. Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. J Clin Invest 2008 Aug, 118(8):2758-2770.
    • (2008) J Clin Invest , vol.118 , Issue.8 , pp. 2758-2770
    • Lim, B.K.1    Xiong, D.2    Dorner, A.3    Youn, T.J.4    Yung, A.5    Liu, T.I.6
  • 44
    • 53349097084 scopus 로고    scopus 로고
    • The tight junction protein CAR regulates cardiac conduction and cell-cell communication
    • Lisewski U., Shi Y., Wrackmeyer U., Fischer R., Chen C., Schirdewan A., et al. The tight junction protein CAR regulates cardiac conduction and cell-cell communication. J Exp Med 2008 Sep 29, 205(10):2369-2379.
    • (2008) J Exp Med , vol.205 , Issue.10 , pp. 2369-2379
    • Lisewski, U.1    Shi, Y.2    Wrackmeyer, U.3    Fischer, R.4    Chen, C.5    Schirdewan, A.6
  • 45
    • 0034679297 scopus 로고    scopus 로고
    • Identification of a deletion in plakoglobin in arrhythmogenic right ventricular cardiomyopathy with palmoplantar keratoderma and woolly hair (Naxos disease)
    • McKoy G., Protonotarios N., Crosby A., Tsatsopoulou A., Anastasakis A., Coonar A., et al. Identification of a deletion in plakoglobin in arrhythmogenic right ventricular cardiomyopathy with palmoplantar keratoderma and woolly hair (Naxos disease). Lancet 2000 Jun 17, 355(9221):2119-2124.
    • (2000) Lancet , vol.355 , Issue.9221 , pp. 2119-2124
    • McKoy, G.1    Protonotarios, N.2    Crosby, A.3    Tsatsopoulou, A.4    Anastasakis, A.5    Coonar, A.6
  • 46
    • 33745848407 scopus 로고    scopus 로고
    • Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy
    • Garcia-Gras E., Lombardi R., Giocondo M.J., Willerson J.T., Schneider M.D., Khoury D.S., et al. Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy. J Clin Invest 2006 Jul, 116(7):2012-2021.
    • (2006) J Clin Invest , vol.116 , Issue.7 , pp. 2012-2021
    • Garcia-Gras, E.1    Lombardi, R.2    Giocondo, M.J.3    Willerson, J.T.4    Schneider, M.D.5    Khoury, D.S.6
  • 47
    • 0034681226 scopus 로고    scopus 로고
    • Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy
    • Naga Prasad S.V., Esposito G., Mao L., Koch W.J., Rockman H.A. Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy. J Biol Chem 2000 Feb 18, 275(7):4693-4698.
    • (2000) J Biol Chem , vol.275 , Issue.7 , pp. 4693-4698
    • Naga Prasad, S.V.1    Esposito, G.2    Mao, L.3    Koch, W.J.4    Rockman, H.A.5
  • 48
    • 44449086630 scopus 로고    scopus 로고
    • Loss of PI3 kinase gamma leads to an accelerated progression to dilated cardiomyopathy in response to pressure overload
    • Oudit G.Y., Kassiri Z., Crackower M.A., Penninger J.M., Backx P.H. Loss of PI3 kinase gamma leads to an accelerated progression to dilated cardiomyopathy in response to pressure overload. Circ Suppl 2004, 108:IV-238.
    • (2004) Circ SUPPL , vol.108
    • Oudit, G.Y.1    Kassiri, Z.2    Crackower, M.A.3    Penninger, J.M.4    Backx, P.H.5
  • 49
    • 58549083120 scopus 로고    scopus 로고
    • Distinct roles of GSK-3alpha and GSK-3beta phosphorylation in the heart under pressure overload
    • Matsuda T., Zhai P., Maejima Y., Hong C., Gao S., Tian B., et al. Distinct roles of GSK-3alpha and GSK-3beta phosphorylation in the heart under pressure overload. Proc Natl Acad Sci USA 2008 Dec 30, 105(52):20900-20905.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.52 , pp. 20900-20905
    • Matsuda, T.1    Zhai, P.2    Maejima, Y.3    Hong, C.4    Gao, S.5    Tian, B.6
  • 51
    • 0242381308 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure
    • Oudit G.Y., Crackower M.A., Eriksson U., Sarao R., Kozieradzki I., Sasaki T., et al. Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure. Circulation 2003 Oct 28, 108(17):2147-2152.
    • (2003) Circulation , vol.108 , Issue.17 , pp. 2147-2152
    • Oudit, G.Y.1    Crackower, M.A.2    Eriksson, U.3    Sarao, R.4    Kozieradzki, I.5    Sasaki, T.6
  • 52
    • 10744225737 scopus 로고    scopus 로고
    • Mechanism of enhanced cardiac function in mice with hypertrophy induced by overexpressed Akt
    • Kim Y.K., Kim S.J., Yatani A., Huang Y., Castelli G., Vatner D.E., et al. Mechanism of enhanced cardiac function in mice with hypertrophy induced by overexpressed Akt. J Biol Chem 2003 Nov 28, 278(48):47622-47628.
    • (2003) J Biol Chem , vol.278 , Issue.48 , pp. 47622-47628
    • Kim, Y.K.1    Kim, S.J.2    Yatani, A.3    Huang, Y.4    Castelli, G.5    Vatner, D.E.6
  • 53
    • 33745387361 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 and PTEN deletion enhance cardiac L-type Ca2+ currents via increased PI3Kalpha/PKB signaling
    • Sun H., Kerfant B.G., Zhao D., Trivieri M.G., Oudit G.Y., Penninger J.M., et al. Insulin-like growth factor-1 and PTEN deletion enhance cardiac L-type Ca2+ currents via increased PI3Kalpha/PKB signaling. Circ Res 2006 Jun 9, 98(11):1390-1397.
    • (2006) Circ Res , vol.98 , Issue.11 , pp. 1390-1397
    • Sun, H.1    Kerfant, B.G.2    Zhao, D.3    Trivieri, M.G.4    Oudit, G.Y.5    Penninger, J.M.6
  • 54
    • 64049105965 scopus 로고    scopus 로고
    • Akt regulates L-type Ca2+ channel activity by modulating Cavalpha1 protein stability
    • Catalucci D., Zhang D.H., DeSantiago J., Aimond F., Barbara G., Chemin J., et al. Akt regulates L-type Ca2+ channel activity by modulating Cavalpha1 protein stability. J Cell Biol 2009 Mar 23, 184(6):923-933.
    • (2009) J Cell Biol , vol.184 , Issue.6 , pp. 923-933
    • Catalucci, D.1    Zhang, D.H.2    DeSantiago, J.3    Aimond, F.4    Barbara, G.5    Chemin, J.6
  • 55
    • 70350521076 scopus 로고    scopus 로고
    • Akt increases sarcoplasmic reticulum Ca2+ cycling by direct phosphorylation of phospholamban at Thr17
    • Catalucci D., Latronico M.V., Ceci M., Rusconi F., Young H.S., Gallo P., et al. Akt increases sarcoplasmic reticulum Ca2+ cycling by direct phosphorylation of phospholamban at Thr17. J Biol Chem 2009 Oct 9, 284(41):28180-28187.
    • (2009) J Biol Chem , vol.284 , Issue.41 , pp. 28180-28187
    • Catalucci, D.1    Latronico, M.V.2    Ceci, M.3    Rusconi, F.4    Young, H.S.5    Gallo, P.6
  • 56
    • 0033592754 scopus 로고    scopus 로고
    • Signaling pathways for cardiac hypertrophy and failure
    • Hunter J.J., Chien K.R. Signaling pathways for cardiac hypertrophy and failure. N Engl J Med 1999 Oct 21, 341(17):1276-1283.
    • (1999) N Engl J Med , vol.341 , Issue.17 , pp. 1276-1283
    • Hunter, J.J.1    Chien, K.R.2
  • 57
    • 0038578664 scopus 로고    scopus 로고
    • Calcium and heart failure: the cycle game
    • Chien K.R., Ross J., Hoshijima M. Calcium and heart failure: the cycle game. Nat Med 2003 May, 9(5):508-509.
    • (2003) Nat Med , vol.9 , Issue.5 , pp. 508-509
    • Chien, K.R.1    Ross, J.2    Hoshijima, M.3
  • 59
    • 18644372367 scopus 로고    scopus 로고
    • Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways
    • Crackower M.A., Oudit G.Y., Kozieradzki I., Sarao R., Sun H., Sasaki T., et al. Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways. Cell 2002 Sep 20, 110(6):737-749.
    • (2002) Cell , vol.110 , Issue.6 , pp. 737-749
    • Crackower, M.A.1    Oudit, G.Y.2    Kozieradzki, I.3    Sarao, R.4    Sun, H.5    Sasaki, T.6
  • 60
    • 20344388816 scopus 로고    scopus 로고
    • Cardiac sarcoplasmic reticulum calcium release and load are enhanced by subcellular cAMP elevations in PI3Kgamma-deficient mice
    • Kerfant B.G., Gidrewicz D., Sun H., Oudit G.Y., Penninger J.M., Backx P.H. Cardiac sarcoplasmic reticulum calcium release and load are enhanced by subcellular cAMP elevations in PI3Kgamma-deficient mice. Circ Res 2005 May 27, 96(10):1079-1086.
    • (2005) Circ Res , vol.96 , Issue.10 , pp. 1079-1086
    • Kerfant, B.G.1    Gidrewicz, D.2    Sun, H.3    Oudit, G.Y.4    Penninger, J.M.5    Backx, P.H.6
  • 61
    • 37349012900 scopus 로고    scopus 로고
    • Role of PI3 kinase gamma in excitation-contraction coupling and heart disease
    • Oudit G.Y., Kassiri Z. Role of PI3 kinase gamma in excitation-contraction coupling and heart disease. Cardiovasc Hematol Disord Drug Targets 2007 Dec, 7(4):295-304.
    • (2007) Cardiovasc Hematol Disord Drug Targets , vol.7 , Issue.4 , pp. 295-304
    • Oudit, G.Y.1    Kassiri, Z.2
  • 62
    • 4344714889 scopus 로고    scopus 로고
    • PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects
    • Patrucco E., Notte A., Barberis L., Selvetella G., Maffei A., Brancaccio M., et al. PI3Kgamma modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects. Cell 2004 Aug 6, 118(3):375-387.
    • (2004) Cell , vol.118 , Issue.3 , pp. 375-387
    • Patrucco, E.1    Notte, A.2    Barberis, L.3    Selvetella, G.4    Maffei, A.5    Brancaccio, M.6
  • 63
    • 78549277139 scopus 로고    scopus 로고
    • Loss of PI3K{gamma} Enhances cAMP-Dependent MMP Remodeling of the Myocardial N-Cadherin Adhesion Complexes and Extracellular Matrix in Response to Early Biomechanical Stress
    • Guo D., Kassiri Z., Basu R., Chow F.L., Kandalam V., Damilano F., et al. Loss of PI3K{gamma} Enhances cAMP-Dependent MMP Remodeling of the Myocardial N-Cadherin Adhesion Complexes and Extracellular Matrix in Response to Early Biomechanical Stress. Circ Res 2010 Sep 16.
    • (2010) Circ Res
    • Guo, D.1    Kassiri, Z.2    Basu, R.3    Chow, F.L.4    Kandalam, V.5    Damilano, F.6
  • 64
    • 78549277139 scopus 로고    scopus 로고
    • Loss of PI3K{gamma} Enhances cAMP-Dependent MMP Remodeling of the Myocardial N-Cadherin Adhesion Complexes and Extracellular Matrix in Response to Early Biomechanical Stress
    • Guo D., Kassiri Z., Basu R., Chow F.L., Kandalam V., Damilano F., et al. Loss of PI3K{gamma} Enhances cAMP-Dependent MMP Remodeling of the Myocardial N-Cadherin Adhesion Complexes and Extracellular Matrix in Response to Early Biomechanical Stress. Circ Res 2010 Nov 12, 107(10):1275-1289.
    • (2010) Circ Res , vol.107 , Issue.10 , pp. 1275-1289
    • Guo, D.1    Kassiri, Z.2    Basu, R.3    Chow, F.L.4    Kandalam, V.5    Damilano, F.6
  • 65
    • 35748974863 scopus 로고    scopus 로고
    • Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function
    • Spinale F.G. Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function. Physiol Rev 2007 Oct, 87(4):1285-1342.
    • (2007) Physiol Rev , vol.87 , Issue.4 , pp. 1285-1342
    • Spinale, F.G.1
  • 66
    • 33644800143 scopus 로고    scopus 로고
    • Ischemia-induced cleavage of cadherins in NRK cells requires MT1-MMP (MMP-14)
    • Covington M.D., Burghardt R.C., Parrish A.R. Ischemia-induced cleavage of cadherins in NRK cells requires MT1-MMP (MMP-14). Am J Physiol Ren Physiol 2006 Jan, 290(1):F43-F51.
    • (2006) Am J Physiol Ren Physiol , vol.290 , Issue.1
    • Covington, M.D.1    Burghardt, R.C.2    Parrish, A.R.3
  • 67
    • 57749206155 scopus 로고    scopus 로고
    • MMP-9 and -12 cause N-cadherin shedding and thereby beta-catenin signalling and vascular smooth muscle cell proliferation
    • Dwivedi A., Slater S.C., George S.J. MMP-9 and -12 cause N-cadherin shedding and thereby beta-catenin signalling and vascular smooth muscle cell proliferation. Cardiovasc Res 2009 Jan 1, 81(1):178-186.
    • (2009) Cardiovasc Res , vol.81 , Issue.1 , pp. 178-186
    • Dwivedi, A.1    Slater, S.C.2    George, S.J.3
  • 68
    • 14044256554 scopus 로고    scopus 로고
    • Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure
    • Kostetskii I., Li J., Xiong Y., Zhou R., Ferrari V.A., Patel V.V., et al. Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure. Circ Res 2005 Feb 18, 96(3):346-354.
    • (2005) Circ Res , vol.96 , Issue.3 , pp. 346-354
    • Kostetskii, I.1    Li, J.2    Xiong, Y.3    Zhou, R.4    Ferrari, V.A.5    Patel, V.V.6
  • 69
    • 0038464639 scopus 로고    scopus 로고
    • Phospholamban: a crucial regulator of cardiac contractility
    • MacLennan D.H., Kranias E.G. Phospholamban: a crucial regulator of cardiac contractility. Nat Rev Mol Cell Biol 2003 Jul, 4(7):566-577.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , Issue.7 , pp. 566-577
    • MacLennan, D.H.1    Kranias, E.G.2
  • 70
    • 2442501143 scopus 로고    scopus 로고
    • Phospholamban gene ablation improves calcium transients but not cardiac function in a heart failure model
    • Janczewski A.M., Zahid M., Lemster B.H., Frye C.S., Gibson G., Higuchi Y., et al. Phospholamban gene ablation improves calcium transients but not cardiac function in a heart failure model. Cardiovasc Res 2004 Jun 1, 62(3):468-480.
    • (2004) Cardiovasc Res , vol.62 , Issue.3 , pp. 468-480
    • Janczewski, A.M.1    Zahid, M.2    Lemster, B.H.3    Frye, C.S.4    Gibson, G.5    Higuchi, Y.6
  • 71
    • 0036164401 scopus 로고    scopus 로고
    • Hypertrophy and functional alterations in hyperdynamic phospholamban-knockout mouse hearts under chronic aortic stenosis
    • Kiriazis H., Sato Y., Kadambi V.J., Schmidt A.G., Gerst M.J., Hoit B.D., et al. Hypertrophy and functional alterations in hyperdynamic phospholamban-knockout mouse hearts under chronic aortic stenosis. Cardiovasc Res 2002 Feb 1, 53(2):372-381.
    • (2002) Cardiovasc Res , vol.53 , Issue.2 , pp. 372-381
    • Kiriazis, H.1    Sato, Y.2    Kadambi, V.J.3    Schmidt, A.G.4    Gerst, M.J.5    Hoit, B.D.6
  • 72
    • 0037362850 scopus 로고    scopus 로고
    • Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy
    • Song Q., Schmidt A.G., Hahn H.S., Carr A.N., Frank B., Pater L., et al. Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy. J Clin Invest 2003 Mar, 111(6):859-867.
    • (2003) J Clin Invest , vol.111 , Issue.6 , pp. 859-867
    • Song, Q.1    Schmidt, A.G.2    Hahn, H.S.3    Carr, A.N.4    Frank, B.5    Pater, L.6
  • 73
    • 1442306221 scopus 로고    scopus 로고
    • Identification of biochemical adaptations in hyper- or hypocontractile hearts from phospholamban mutant mice by expression proteomics
    • Pan Y., Kislinger T., Gramolini A.O., Zvaritch E., Kranias E.G., MacLennan D.H., et al. Identification of biochemical adaptations in hyper- or hypocontractile hearts from phospholamban mutant mice by expression proteomics. Proc Natl Acad Sci USA 2004 Feb 24, 101(8):2241-2246.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.8 , pp. 2241-2246
    • Pan, Y.1    Kislinger, T.2    Gramolini, A.O.3    Zvaritch, E.4    Kranias, E.G.5    MacLennan, D.H.6
  • 74
    • 0037040839 scopus 로고    scopus 로고
    • Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure
    • Shai S.Y., Harpf A.E., Babbitt C.J., Jordan M.C., Fishbein M.C., Chen J., et al. Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure. Circ Res 2002 Mar 8, 90(4):458-464.
    • (2002) Circ Res , vol.90 , Issue.4 , pp. 458-464
    • Shai, S.Y.1    Harpf, A.E.2    Babbitt, C.J.3    Jordan, M.C.4    Fishbein, M.C.5    Chen, J.6
  • 75
    • 85047687537 scopus 로고    scopus 로고
    • Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human
    • Haghighi K., Kolokathis F., Pater L., Lynch R.A., Asahi M., Gramolini A.O., et al. Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human. J Clin Invest 2003 Mar, 111(6):869-876.
    • (2003) J Clin Invest , vol.111 , Issue.6 , pp. 869-876
    • Haghighi, K.1    Kolokathis, F.2    Pater, L.3    Lynch, R.A.4    Asahi, M.5    Gramolini, A.O.6
  • 76
    • 0033535942 scopus 로고    scopus 로고
    • Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice
    • Engelhardt S., Hein L., Wiesmann F., Lohse M.J. Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice. Proc Natl Acad Sci USA 1999 Jun 8, 96(12):7059-7064.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.12 , pp. 7059-7064
    • Engelhardt, S.1    Hein, L.2    Wiesmann, F.3    Lohse, M.J.4
  • 77
    • 0035656783 scopus 로고    scopus 로고
    • Early impairment of calcium handling and altered expression of junctin in hearts of mice overexpressing the beta1-adrenergic receptor
    • Engelhardt S., Boknik P., Keller U., Neumann J., Lohse M.J., Hein L. Early impairment of calcium handling and altered expression of junctin in hearts of mice overexpressing the beta1-adrenergic receptor. FASEB J 2001 Dec, 15(14):2718-2720.
    • (2001) FASEB J , vol.15 , Issue.14 , pp. 2718-2720
    • Engelhardt, S.1    Boknik, P.2    Keller, U.3    Neumann, J.4    Lohse, M.J.5    Hein, L.6
  • 78
    • 0028263498 scopus 로고
    • Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor
    • Milano C.A., Allen L.F., Rockman H.A., Dolber P.C., McMinn T.R., Chien K.R., et al. Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor. Science 1994 Apr 22, 264(5158):582-586.
    • (1994) Science , vol.264 , Issue.5158 , pp. 582-586
    • Milano, C.A.1    Allen, L.F.2    Rockman, H.A.3    Dolber, P.C.4    McMinn, T.R.5    Chien, K.R.6
  • 79
    • 0037352911 scopus 로고    scopus 로고
    • Altered calcium transient and development of hypertrophy in beta2-adrenoceptor overexpressing mice with and without pressure overload
    • Schwarz B., Percy E., Gao X.M., Dart A.M., Richardt G., Du X.J. Altered calcium transient and development of hypertrophy in beta2-adrenoceptor overexpressing mice with and without pressure overload. Eur J Heart Fail 2003 Mar, 5(2):131-136.
    • (2003) Eur J Heart Fail , vol.5 , Issue.2 , pp. 131-136
    • Schwarz, B.1    Percy, E.2    Gao, X.M.3    Dart, A.M.4    Richardt, G.5    Du, X.J.6
  • 80
    • 0034602839 scopus 로고    scopus 로고
    • Beta(2)-adrenergic receptor overexpression exacerbates development of heart failure after aortic stenosis
    • Du X.J., Autelitano D.J., Dilley R.J., Wang B., Dart A.M., Woodcock E.A. beta(2)-adrenergic receptor overexpression exacerbates development of heart failure after aortic stenosis. Circulation 2000 Jan 4-11, 101(1):71-77.
    • (2000) Circulation , vol.101 , Issue.1 , pp. 71-77
    • Du, X.J.1    Autelitano, D.J.2    Dilley, R.J.3    Wang, B.4    Dart, A.M.5    Woodcock, E.A.6
  • 81
    • 43449137867 scopus 로고    scopus 로고
    • Sympathetic activation causes focal adhesion signaling alteration in early compensated volume overload attributable to isolated mitral regurgitation in the dog
    • Sabri A., Rafiq K., Seqqat R., Kolpakov M.A., Dillon R., Dell'italia L.J. Sympathetic activation causes focal adhesion signaling alteration in early compensated volume overload attributable to isolated mitral regurgitation in the dog. Circ Res 2008 May 9, 102(9):1127-1136.
    • (2008) Circ Res , vol.102 , Issue.9 , pp. 1127-1136
    • Sabri, A.1    Rafiq, K.2    Seqqat, R.3    Kolpakov, M.A.4    Dillon, R.5    Dell'italia, L.J.6
  • 82
    • 77955702308 scopus 로고    scopus 로고
    • Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload
    • Guellich A., Gao S., Hong C., Yan L., Wagner T.E., Dhar S.K., et al. Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload. Am J Physiol Heart Circ Physiol 2010 Sep, 299(3):H707-H712.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299 , Issue.3
    • Guellich, A.1    Gao, S.2    Hong, C.3    Yan, L.4    Wagner, T.E.5    Dhar, S.K.6
  • 83
    • 76649092318 scopus 로고    scopus 로고
    • Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging
    • Wittkopper K., Fabritz L., Neef S., Ort K.R., Grefe C., Unsold B., et al. Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging. J Clin Invest 2010 Feb 1, 120(2):617-626.
    • (2010) J Clin Invest , vol.120 , Issue.2 , pp. 617-626
    • Wittkopper, K.1    Fabritz, L.2    Neef, S.3    Ort, K.R.4    Grefe, C.5    Unsold, B.6
  • 84
    • 1642388834 scopus 로고    scopus 로고
    • PKC-alpha regulates cardiac contractility and propensity toward heart failure
    • Braz J.C., Gregory K., Pathak A., Zhao W., Sahin B., Klevitsky R., et al. PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nat Med 2004 Mar, 10(3):248-254.
    • (2004) Nat Med , vol.10 , Issue.3 , pp. 248-254
    • Braz, J.C.1    Gregory, K.2    Pathak, A.3    Zhao, W.4    Sahin, B.5    Klevitsky, R.6
  • 85
    • 68049086486 scopus 로고    scopus 로고
    • Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach
    • Liu Q., Chen X., Macdonnell S.M., Kranias E.G., Lorenz J.N., Leitges M., et al. Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach. Circ Res 2009 Jul 17, 105(2):194-200.
    • (2009) Circ Res , vol.105 , Issue.2 , pp. 194-200
    • Liu, Q.1    Chen, X.2    Macdonnell, S.M.3    Kranias, E.G.4    Lorenz, J.N.5    Leitges, M.6
  • 86
    • 72449199923 scopus 로고    scopus 로고
    • Src, PKCalpha, and PKCdelta are required for alphavbeta3 integrin-mediated metastatic melanoma invasion
    • Putnam A.J., Schulz V.V., Freiter E.M., Bill H.M., Miranti C.K. Src, PKCalpha, and PKCdelta are required for alphavbeta3 integrin-mediated metastatic melanoma invasion. Cell Commun Signal 2009, 7:10.
    • (2009) Cell Commun Signal , vol.7 , pp. 10
    • Putnam, A.J.1    Schulz, V.V.2    Freiter, E.M.3    Bill, H.M.4    Miranti, C.K.5
  • 87
    • 70350513886 scopus 로고    scopus 로고
    • The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications
    • Triposkiadis F., Karayannis G., Giamouzis G., Skoularigis J., Louridas G., Butler J. The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications. J Am Coll Cardiol 2009 Nov 3, 54(19):1747-1762.
    • (2009) J Am Coll Cardiol , vol.54 , Issue.19 , pp. 1747-1762
    • Triposkiadis, F.1    Karayannis, G.2    Giamouzis, G.3    Skoularigis, J.4    Louridas, G.5    Butler, J.6
  • 88
    • 0026501307 scopus 로고
    • The effects of acute and chronic cocaine use on the heart
    • Kloner R.A., Hale S., Alker K., Rezkalla S. The effects of acute and chronic cocaine use on the heart. Circulation 1992 Feb, 85(2):407-419.
    • (1992) Circulation , vol.85 , Issue.2 , pp. 407-419
    • Kloner, R.A.1    Hale, S.2    Alker, K.3    Rezkalla, S.4
  • 89
    • 33745436678 scopus 로고    scopus 로고
    • Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review
    • Gianni M., Dentali F., Grandi A.M., Sumner G., Hiralal R., Lonn E. Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review. Eur Heart J 2006 Jul, 27(13):1523-1529.
    • (2006) Eur Heart J , vol.27 , Issue.13 , pp. 1523-1529
    • Gianni, M.1    Dentali, F.2    Grandi, A.M.3    Sumner, G.4    Hiralal, R.5    Lonn, E.6
  • 90
    • 0028351475 scopus 로고
    • Evaluation of the effect of phosphodiesterase inhibitors on mortality in chronic heart failure patients. A meta-analysis
    • Nony P., Boissel J.P., Lievre M., Leizorovicz A., Haugh M.C., Fareh S., et al. Evaluation of the effect of phosphodiesterase inhibitors on mortality in chronic heart failure patients. A meta-analysis. Eur J Clin Pharmacol 1994, 46(3):191-196.
    • (1994) Eur J Clin Pharmacol , vol.46 , Issue.3 , pp. 191-196
    • Nony, P.1    Boissel, J.P.2    Lievre, M.3    Leizorovicz, A.4    Haugh, M.C.5    Fareh, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.