Understanding TR binding to pMHC complexes: How does a TR scan many pMHC complexes yet preferentially bind to one

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  Khan, Javed Mohammed ^a   Ranganathan, Shoba ^a,b  

^a MACQUARIE UNIVERSITY   (Australia)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; EPITOPE; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN; T LYMPHOCYTE RECEPTOR; HLA ANTIGEN CLASS 1; LYMPHOCYTE ANTIGEN RECEPTOR; MULTIPROTEIN COMPLEX;

ADAPTIVE IMMUNITY; ARTICLE; CALCULATION; CODON; CRYSTALLOGRAPHY; LYMPHOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR DOCKING; PROTEIN INTERACTION; RECEPTOR BINDING; T LYMPHOCYTE; ANIMAL; BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPREHENSION; DRUG POTENTIATION; ENERGY METABOLISM; ENZYME SPECIFICITY; HUMAN; IMMUNOLOGY; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN BINDING; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE;

ANIMALS; COMPREHENSION; ENERGY METABOLISM; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; LYMPHOCYTE ACTIVATION; MICE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, ANTIGEN, T-CELL; SUBSTRATE SPECIFICITY; T-CELL ANTIGEN RECEPTOR SPECIFICITY;

EID: 79952045349     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017194     Document Type: Article

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