메뉴 건너뛰기




Volumn 124, Issue 1-2, 2011, Pages 25-30

Estrogenic effect of the MEK1 inhibitor PD98059 on endogenous estrogen receptor alpha and beta

Author keywords

Estrogen receptors; Flavone; Gene expression; Mammary epithelial cells; PD98059

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; SMALL INTERFERING RNA;

EID: 79952040108     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2010.12.020     Document Type: Article
Times cited : (9)

References (22)
  • 1
    • 69249137029 scopus 로고    scopus 로고
    • Biological determinants of endocrine resistance in breast cancer
    • E.A. Musgrove, and R.L. Sutherland Biological determinants of endocrine resistance in breast cancer Nat. Rev. Cancer 9 2009 631 643
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 631-643
    • Musgrove, E.A.1    Sutherland, R.L.2
  • 2
    • 18844429222 scopus 로고    scopus 로고
    • Reflections on the discovery and significance of estrogen receptor β
    • DOI 10.1210/er.2004-0027
    • K.F. Koehler, L.A. Helguero, L. Haldosén, M. Warner, and J. Gustafsson Reflections on the discovery and significance of estrogen receptor beta Endocr. Rev. 26 2005 465 478 (Pubitemid 40691301)
    • (2005) Endocrine Reviews , vol.26 , Issue.3 , pp. 465-478
    • Koehler, K.F.1    Helguero, L.A.2    Haldosen, L.-A.3    Warner, M.4    Gustafsson, J.-A.5
  • 3
    • 33947674663 scopus 로고    scopus 로고
    • New perspectives into the biological and clinical relevance of oestrogen receptors in the human breast
    • DOI 10.1002/path.2130
    • V. Speirs, and R.A. Walker New perspectives into the biological and clinical relevance of oestrogen receptors in the human breast J. Pathol. 211 2007 499 506 (Pubitemid 46502425)
    • (2007) Journal of Pathology , vol.211 , Issue.5 , pp. 499-506
    • Speirs, V.1    Walker, R.A.2
  • 4
    • 27144524273 scopus 로고    scopus 로고
    • Estrogen receptors alfa (ERα) and beta (ERβ) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11
    • DOI 10.1038/sj.onc.1208807, PII 1208807
    • L.A. Helguero, M.H. Faulds, J. Gustafsson, and L. Haldosén Estrogen receptors alfa (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11 Oncogene 24 2005 6605 6616 (Pubitemid 41486791)
    • (2005) Oncogene , vol.24 , Issue.44 , pp. 6605-6616
    • Helguero, L.A.1    Faulds, M.H.2    Gustafsson, J.-A.3    Haldosen, L.-A.4
  • 6
    • 0035935731 scopus 로고    scopus 로고
    • Estrogen receptor-β potency-selective ligands: Structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues
    • DOI 10.1021/jm010254a
    • M.J. Meyers, J. Sun, K.E. Carlson, G.A. Marriner, B.S. Katzenellenbogen, and J.A. Katzenellenbogen Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues J. Med. Chem. 44 2001 4230 4251 (Pubitemid 33095330)
    • (2001) Journal of Medicinal Chemistry , vol.44 , Issue.24 , pp. 4230-4251
    • Meyers, M.J.1    Sun, J.2    Carlson, K.E.3    Marriner, G.A.4    Katzenellenbogen, B.S.5    Katzenellenbogen, J.A.6
  • 8
    • 39049146064 scopus 로고    scopus 로고
    • Effect of dietary flavonoids on pathways involved in drug metabolism
    • DOI 10.1517/17425255.4.1.17
    • R. Cermak Effect of dietary flavonoids on pathways involved in drug metabolism Expert Opin. Drug Metab. Toxicol. 4 2008 17 35 (Pubitemid 351234098)
    • (2008) Expert Opinion on Drug Metabolism and Toxicology , vol.4 , Issue.1 , pp. 17-35
    • Cermak, R.1
  • 11
    • 16544389527 scopus 로고    scopus 로고
    • Differential effects of PD98059 and U0126 on osteogenesis and adipogenesis
    • Z. Dang, and C.W.G.M. Lowik Differential effects of PD98059 and U0126 on osteogenesis and adipogenesis J. Cell. Biochem. 92 2004 525 533
    • (2004) J. Cell. Biochem. , vol.92 , pp. 525-533
    • Dang, Z.1    Lowik, C.W.G.M.2
  • 12
    • 0442279183 scopus 로고    scopus 로고
    • Estrogen Receptor Functional Activity Changes during Differentiation of Mammary Epithelial Cells
    • DOI 10.1210/me.2003-0290
    • M.H. Faulds, H. Olsen, L.A. Helguero, J. Gustafsson, and L. Haldosén Estrogen receptor functional activity changes during differentiation of mammary epithelial cells Mol. Endocrinol. 18 2004 412 421 (Pubitemid 38185881)
    • (2004) Molecular Endocrinology , vol.18 , Issue.2 , pp. 412-421
    • Faulds, M.H.1    Olsen, H.2    Helguero, L.A.3    Gustafsson, J.-A.4    Haldosen, L.-A.5
  • 13
    • 0035210802 scopus 로고    scopus 로고
    • Evidence for estrogenic contamination of the MAPK inhibitor PD98059
    • DOI 10.1210/en.142.12.5390
    • X. Long, E.A. Gize, K. Nephew, and R.M. Bigsby Evidence for estrogenic contamination of the MAPK inhibitor PD98059 Endocrinology 142 2001 5390 5393 (Pubitemid 33131973)
    • (2001) Endocrinology , vol.142 , Issue.12 , pp. 5390-5393
    • Long, X.1    Gize, E.A.2    Nephew, K.3    Bigsby, R.M.4
  • 15
    • 12144269500 scopus 로고    scopus 로고
    • Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer
    • C.K. Osborne, J. Shou, S. Massarweh, and R. Schiff Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer Clin. Cancer Res. 11 2005 865s 870s (Pubitemid 40111098)
    • (2005) Clinical Cancer Research , vol.11 , Issue.2
    • Osborne, C.K.1    Shou, J.2    Massarweh, S.3    Schiff, R.4    Come, S.5    Santen, R.6    Johnston, S.7
  • 16
    • 0033054361 scopus 로고    scopus 로고
    • Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line
    • DOI 10.1093/toxsci/48.1.55
    • J. Legler, C.E. van den Brink, A. Brouwer, A.J. Murk, P.T. van der Saag, A.D. Vethaak, and B. van der Burg Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line Toxicol. Sci. 48 1999 55 66 (Pubitemid 29244421)
    • (1999) Toxicological Sciences , vol.48 , Issue.1 , pp. 55-66
    • Legler, J.1    Van Den Brink, C.E.2    Brouwer, A.3    Murk, A.J.4    Van Der Saag, P.T.5    Vethaak, A.D.6    Van Der Burg, B.7
  • 17
    • 33751552134 scopus 로고    scopus 로고
    • Kinase-specific phosphorylation of the estrogen receptor changes receptor interactions with ligand, deoxyribonucleic acid, and coregulators associated with alterations in estrogen and tamoxifen activity
    • DOI 10.1210/me.2006-0068
    • V.S. Likhite, F. Stossi, K. Kim, B.S. Katzenellenbogen, and J.A. Katzenellenbogen Kinase-specific phosphorylation of the estrogen receptor changes receptor interactions with ligand, deoxyribonucleic acid, and coregulators associated with alterations in estrogen and tamoxifen activity Mol. Endocrinol. 12 2006 3120 3132 (Pubitemid 44833560)
    • (2006) Molecular Endocrinology , vol.20 , Issue.12 , pp. 3120-3132
    • Likhite, V.S.1    Stossi, F.2    Kim, K.3    Katzenellenbogen, B.S.4    Katzenellenbogen, J.A.5
  • 18
    • 0030589078 scopus 로고    scopus 로고
    • Comparative effects of flavonoids and model inducers on drug-metabolizing enzymes in rat liver
    • DOI 10.1016/S0300-483X(96)03412-9, PII S0300483X96034129
    • M.C. Canivenc-Lavier, M.F. Vernevaut, M. Totis, M.H. Siess, J. Magdalou, and M. Suschetet Comparative effects of flavonoids and model inducers on drug-metabolizing enzymes in rat liver Toxicology 114 1996 19 27 (Pubitemid 26379364)
    • (1996) Toxicology , vol.114 , Issue.1 , pp. 19-27
    • Canivenc-Lavier, M.-C.1    Vernevaut, M.-F.2    Totis, M.3    Siess, M.-H.4    Magdalou, J.5    Suschetet, M.6
  • 19
    • 0023887725 scopus 로고    scopus 로고
    • Comparison of the effects of feeding quercetin or flavone on hepatic and intestinal drug-metabolizing enzymes of the rat
    • C. Brouard, M.H. Siess, M.F. Vernevaut, and M. Suschetet Comparison of the effects of feeding quercetin or flavone on hepatic and intestinal drug-metabolizing enzymes of the rat Food Chem. Toxicol. 26 1998 99 103
    • (1998) Food Chem. Toxicol. , vol.26 , pp. 99-103
    • Brouard, C.1    Siess, M.H.2    Vernevaut, M.F.3    Suschetet, M.4
  • 20
    • 0031956424 scopus 로고    scopus 로고
    • PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase
    • J.J. Reiners, J.-Y. Lee, R.E. Clift, D.T. Dudley, and S.P. Myrand PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase Mol. Pharmacol. 53 1998 438 445 (Pubitemid 28162865)
    • (1998) Molecular Pharmacology , vol.53 , Issue.3 , pp. 438-445
    • Reiners Jr., J.J.1    Lee, J.-Y.2    Clift, R.E.3    Dudley, D.T.4    Myrand, S.P.5
  • 21
    • 67650848116 scopus 로고    scopus 로고
    • Endocrine disruptive chemicals: Mechanisms of action and involvement in metabolic disorders
    • E. Swedenborg, J. Rüegg, S. Mäkelä, and Pongratz Endocrine disruptive chemicals: mechanisms of action and involvement in metabolic disorders J. Mol. Endocrinol. 43 2009 1 10
    • (2009) J. Mol. Endocrinol. , vol.43 , pp. 1-10
    • Swedenborg, E.1    Rüegg, J.2    Mäkelä, S.3
  • 22
    • 38749143249 scopus 로고    scopus 로고
    • The transcription factor aryl hydrocarbon receptor nuclear translocator functions as an estrogen receptor β-selective coactivator, and its recruitment to alternative pathways mediates antiestrogenic effects of dioxin
    • DOI 10.1210/me.2007-0128
    • J. Rüegg, E. Swedenborg, D. Wahlström, A. Escande, P. Balaguer, K. Pettersson, and I. Pongratz The transcription factor aryl hydrocarbon receptor nuclear translocator functions as an estrogen receptor beta-selective coactivator, and its recruitment to alternative pathways mediates antiestrogenic effects of dioxin Mol. Endocrinol. 22 2008 304 316 (Pubitemid 351185933)
    • (2008) Molecular Endocrinology , vol.22 , Issue.2 , pp. 304-316
    • Ruegg, J.1    Swedenborg, E.2    Wahlstrom, D.3    Escande, A.4    Balaguer, P.5    Pettersson, K.6    Pongratz, I.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.