Estrogen Receptor Functional Activity Changes during Differentiation of Mammary Epithelial Cells

Molecular Endocrinology

Volumn 18, Issue 2, 2004, Pages 412-421

  Faulds, Malin Hedengran ^a   Olsen, Hanne ^a   Helguero, Luisa A ^a   Gustafsson, Jan Åke ^a   Haldosén, Lars Arne ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CASEIN; ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; BREAST EPITHELIUM; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; GENE CONTROL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; SIGNAL TRANSDUCTION;

ANIMALS; CASEINS; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; DNA-BINDING PROTEINS; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; EPITHELIAL CELLS; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; MAMMARY GLANDS, ANIMAL; MAP KINASE SIGNALING SYSTEM; MICE; MILK PROTEINS; PROMOTER REGIONS (GENETICS); RECEPTORS, CYTOPLASMIC AND NUCLEAR; RESPONSE ELEMENTS; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0442279183     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2003-0290     Document Type: Article

References (37)

1. Bocchinfuso WP, Korach KS 1997 Mammary gland development and tumorigenesis in estrogen receptor knockout mice. J Mammary Gland Biol Neoplasia 2:323-34
2. Weihua Z, Andersson S, Cheng G, Simpson ER, Warner M, Gustafsson J-Å 2003 Update on estrogen signaling. FEBS Lett 546:17-24
3. Darnell JE, Jr, Kerr IM, Stark GR 1994 Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264: 1415-1421
4. Schindler C, Darnell Jr JE 1995 Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu Rev Biochem 64:621-651
5. Ihle JN 1996 STATs: signal transducers and activators of transcription. Cell 84:331-334
6. Burdon TG, Maitland KA, Clark AJ, Wallace R, Watson CJ 1994 Regulation of the sheep β-lactoglobulin gene by lactogenic hormones is mediated by a transcription factor that binds an interferon-γ activation site-related element. Mol Endocrinol 8:1528-1536
7. Schmitt-Ney M, Doppler W, Ball RK, Groner B 1991 β-Casein gene promoter activity is regulated by the hormone-mediated relief of transcriptional repression and a mammary-gland-specific nuclear factor. Mol Cell Biol 11:3745-3755
8. Liu X, Robinson GW, Wagner KU, Garrett L, Wynshaw-Boris A, Hennighausen L 1997 Stat5a is mandatory for adult mammary gland development and lactogenesis. Genes Dev 11:179-186
9. Udy GB, Towers RP, Snell RG, Wilkins RJ, Park SH, Ram PA, Waxman DJ, Davey HW 1997 Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression. Proc Natl Acad Sci USA 94: 7239-7244
10. Schroeder JA, Lee DC 1998 Dynamic expression and activation of ERBB receptors in the developing mouse mammary gland. Cell Growth Differ 9:451-464
11. Sebastian J, Richards RG, Walker MP, Wiesen JF, Werb Z, Derynck R, Hom YK, Cunha GR, DiAugustine RP 1998 Activation and function of the epidermal growth factor receptor and erbB-2 during mammary gland morphogenesis. Cell Growth Differ 9:777-785
12. Boonstra J, Rijken P, Humbel B, Cremers F, Verkleij A, van Bergen en Henegouwen P 1995 The epidermal growth factor. Cell Biol Int 19:413-430
13. Bunone G, Briand PA, Miksicek RJ, Picard D 1996 Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO J 15:2174-2183
14. Kato S, Endoh H, Masuhiro Y, Kitamoto T, Uchiyama S, Sasaki H, Masushige S, Gotoh Y, Nishida E, Kawashima H, Metzger D, Chambon P 1995 Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270:1491-1494
15. Tremblay A, Tremblay GB, Labrie F, Giguere V 1999 Ligand-independent recruitment of SRC-1 to estrogen receptor β through phosphorylation of activation function AF-1. Mol Cell 3:513-519
16. Ankrapp DP, Bennett JM, Haslam SZ 1998 Role of epidermal growth factor in the acquisition of ovarian steroid hormone responsiveness in the normal mouse mammary gland. J Cell Physiol 174:251-260
17. Vanderboom RJ, Sheffield LG 1993 Estrogen enhances epidermal growth factor-induced DNA synthesis in mammary epithelial cells. J Cell Physiol 156:367-372
18. Faulds MH, Pettersson K, Gustafsson J-Å, Haldosen LA 2001 Cross-talk between ERs and signal transducer and activator of transcription 5 is E2 dependent and involves two functionally separate mechanisms. Mol Endocrinol 15:1929-1940
19. Petersen H, Haldosen LA 1998 EGF modulates expression of STATS in mammary epithelial cells. Exp Cell Res 243:347-358
20. Ball RK, Friis RR, Schoenenberger CA, Doppler W, Groner B 1988 Prolactin regulation of β-casein gene expression and of a cytosolic 120-kd protein in a cloned mouse mammary epithelial cell line. EMBO J 7:2089-2095
21. Schams D, Kohlenberg S, Amselgruber W, Berisha B, Pfaffl MW, Sinowatz F 2003 Expression and localisation of oestrogen and progesterone receptors in the bovine mammary gland during development, function and involution. J Endocrinol 177:305-317
22. Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR 1995 PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270:27489-27494
23. McKenna NJ, O'Malley BW 2002 Minireview: nuclear receptor coactivators - an update. Endocrinology 143: 2461-2465
24. Zhang H, Thomsen JS, Johansson L, Gustafsson J-Å, Treuter E 2000 DAX-1 functions as an LXXLL-containing corepressor for activated estrogen receptors. J Biol Chem 275:39855-39859
25. Johansson L, Bavner A, Thomsen JS, Farnegardh M, Gustafsson J-Å, Treuter E 2000 The orphan nuclear receptor SHP utilizes conserved LXXLL-related motifs for interactions with ligand-activated estrogen receptors. Mol Cell Biol 20:1124-1133
26. Onate SA, Tsai SY, Tsai MJ, O'Malley BW 1995 Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270: 1354-1357
27. Leung KC, Doyle N, Ballesteros M, Sjogren K, Watts CK, Low TH, Leong GM, Ross RJ, Ho KK 2003 Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2. Proc Natl Acad Sci USA 100:1016-1021
28. Wyszomierski SL, Yeh J, Rosen JM 1999 Glucocorticoid receptor/signal transducer and activator of transcription 5 (STAT5) interactions enhance STATS activation by prolonging STATS DNA binding and tyrosine phosphorylation. Mol Endocrinol 13:330-343
29. Stern DF 2000 Tyrosine kinase signalling in breast cancer: ErbB family receptor tyrosine kinases. Breast Cancer Res 2:176-183
30. Shyamala G, Ferenczy A 1982 The nonresponsiveness of lactating mammary gland to estradiol. Endocrinology 110:1249-1256
31. Kelsey JJ 1996 Hormonal contraception and lactation. J Hum Lact 12:315-318
32. Kleinberg DL, Todd J, Babitsky G, Greising J 1982 Estradiol inhibits prolactin induced α-lactalbumin production in normal primate mammary tissue in vitro. Endocrinology 110:279-281
33. Humphreys RC, Hennighausen L 1999 Signal transducer and activator of transcription 5a influences mammary epithelial cell survival and tumorigenesis. Cell Growth Differ 10:685-694
34. Atwood CS, Ikeda M, Vonderhaar BK 1995 Involution of mouse mammary glands in whole organ culture: a model for studying programmed cell death. Biochem Biophys Res Commun 207:860-867
35. Ambili M, Jayasree K, Sudhakaran PR 1998 60K gelatinase involved in mammary gland involution is regulated by β-oestradiol. Biochim Biophys Acta 1403:219-231
36. Athie F, Bachman KC, Head HH, Hayen MJ, Wilcox CJ 1996 Estrogen administered at final milk removal accelerates involution of bovine mammary gland. J Dairy Sci 79:220-226
37. Wood TJ, Sliva D, Lobie PE, Pircher TJ, Gouilleux F, Wakao H, Gustafsson J-A, Groner B, Norstedt G, Haldosen LA 1995 Mediation of growth hormone-dependent transcriptional activation by mammary gland factor/Stat 5. J Biol Chem 270:9448-9453