Circulating ghrelin levels and the polycystic ovary syndrome: Correlation with the clinical, hormonal and metabolic features

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 155, Issue 1, 2011, Pages 65-68

  Daghestani, Maha H ^a   Daghestani, Mazin H ^b   El Mazny, Akmal ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b UMM AL QURA UNIVERSITY   (Saudi Arabia)

Author keywords

Body mass index; Fasting and postprandial ghrelin levels; Polycystic ovary syndrome

Indexed keywords

ESTRADIOL; FOLLITROPIN; GHRELIN; GLUCOSE; INSULIN; LUTEINIZING HORMONE; PROGESTERONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE;

ADULT; ANALYSIS OF VARIANCE; ANTHROPOMETRY; ARTICLE; BODY MASS; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; ESTRADIOL BLOOD LEVEL; FEMALE; FOLLITROPIN BLOOD LEVEL; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; LUTEINIZING HORMONE BLOOD LEVEL; METABOLISM; OVARY POLYCYSTIC DISEASE; POSTPRANDIAL STATE; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; SAUDI ARABIA; STUDENT T TEST; TESTOSTERONE BLOOD LEVEL;

EID: 79952037057     PISSN: 03012115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2010.11.019     Document Type: Article

References (28)

1. T.L. Setji, and A.J. Brown Polycystic ovary syndrome: diagnosis and treatment Am J Med 120 2007 128 132 (Pubitemid 46175777)
2. Rotterdam ESHRE/ASRM-sponsored PCOS Consensus Workshop Group Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS) Hum Reprod 19 2004 41 47
3. M.O. Goodarzi, and S.G. Korenman The importance of insulin resistance in polycystic ovary syndrome Fertil Steril 80 2003 255 258 (Pubitemid 36959775)
4. D.A. Ehrmann Polycystic ovary syndrome N Eng J Med 352 2005 1223 1236
5. T.M. Barber, J.A. Wass, M.I. McCarthy, and S. Franks Metabolic characteristics of women with polycystic ovaries and oligoamenorrhoea but normal androgen levels: implications for the management of polycystic ovary syndrome Clin Endrocrinol (oxf) 66 2007 513 517 (Pubitemid 46434931)
6. I. Sakata, and T. Sakai Ghrelin cells in the gastrointestinal tract Int J Pept 2010 1 7
7. A. Asakawa, A. Inui, and T. Kaga Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin Gastroenterology 120 2001 337 345 (Pubitemid 32149296)
8. K. Toshinai, M.S. Mondal, and M. Nakazato Upregulation of ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration Biochem Biophys Res Commun 281 2001 1220 1225 (Pubitemid 32924549)
9. M. Tschop, D.L. Smiley, and M.L. Heiman Ghrelin induces idiposity in rodents Nature 407 2000 2510 2516
10. O. Ukkola, and S. Poykko Ghrelin, growth and obesity Ann Med 34 2 2002 102 108 (Pubitemid 34596848)
11. D.E. Cummings, J.Q. Purnell, R.S. Frayo, K. Schmidova, B.E. Wisse, and D.S. Weigle A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans Diabetes 50 8 2001 1714 1719 (Pubitemid 33641587)
12. O. Ukkola, E. Ravussin, and P. Jacobson Role of ghrelin polymorphisms in obesity based on three different studies Obes Res 10 8 2002 782 791 (Pubitemid 135687519)
13. D. Glintborg, M. Andersen, and C. Hagen Evaluation of metabolic risk markers in polycystic ovary syndrome (PCOS). Adiponectin, ghrelin, leptin and body composition in hirsute PCOS patients and controls Eur J Endocrinol 155 2 2006 337 345 (Pubitemid 44269452)
14. D. Micic, M. Sumarac-Dumanovic, and A. Kendereski Total ghrelin levels during acute insulin infusion in patients with polycystic ovary syndrome J Endocrinol Invest 30 10 2007 820 827 (Pubitemid 351166303)
15. L.J. Moran, M. Noakes, and P.M. Clifton Postprandial ghrelin, cholecystokinin, peptide YY, and appetite before and after weight loss in overweight women with and without polycystic ovary syndrome Am J Clin Nutr 86 6 2007 1603 1610 (Pubitemid 350232173)
16. T.M. Barber, F.F. Casanueva, and F. Karpe Ghrelin levels are suppressed and show a blunted response to oral glucose in women with polycystic ovary syndrome Eur J Endocrinol 158 4 2008 511 516 (Pubitemid 351606346)
17. C. Schofl, R. Horn, T. Schill, H.W. Schlosser, M.J. Muller, and G. Brabant Circulating ghrelin levels in patients with polycystic ovary syndrome J Clin Endocrinol Metab 87 10 2002 4607 4610 (Pubitemid 35247048)
18. F. Orio Jr., P. Lucidi, and S. Palomba Circulating ghrelin concentrations in the polycystic ovary syndrome J Clin Endocrinol Metab 88 2 2003 942 945 (Pubitemid 36207846)
19. R. Waśko, H. Komarowska, A. Warenik-Szymankiewicz, and J. Sowiński Elevated ghrelin plasma levels in patients with polycystic ovary syndrome Horm Metab Res 36 2004 170 173 (Pubitemid 38510038)
20. J. Skommer, K. Katulski, and E. Poreba Gherlin expression in women with polycystic ovary syndrome - a preliminary study Eur J Gynaecol Oncol 26 5 2005 553 556 (Pubitemid 41585945)
21. H. Komarowska, R. Waśko, and K. Iwanik Ghrelin ovarian cell expression in patients with polycystic ovary syndrome: an immunohistochemical evaluation Horm Metab Res 38 12 2006 783 788 (Pubitemid 46051497)
22. W. Bik, A. Baranowska-Bik, E. Wolinska-Witort, M. Chmielowska, L. Martynska, and B. Baranowska The relationship between metabolic status and levels of adiponectin and ghrelin in lean women with polycystic ovary syndrome Gynecol Endocrinol 23 6 2007 325 331 (Pubitemid 47038249)
23. M. Tschop, C. Weyer, P.A. Tataranni, V. Devanarayan, E. Ravussin, and M.L. Heiman Circulating ghrelin levels are decreased in human obesity Diabetes 50 4 2001 707 709 (Pubitemid 32242624)
24. D. Panidis, C. Asteriadis, and N.A. Georgopoulos Decreased active, total and altered active to total ghrelin ratio in normal weight women with the more severe form of polycystic ovary syndrome Eur J Obstet Gynecol Reprod Biol 149 2010 170 174
25. A. Dunaif Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis Endocr Rev 18 6 1997 774 800 (Pubitemid 28009567)
26. F. Broglio, E. Arvat, and A. Benso Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans J Clin Endocrinol Metab 86 10 2001 5083 5086 (Pubitemid 33020569)
27. M.F. Saad, B. Bernaba, and C.M. Hwyu Insulin regulates plasma ghrelin concentration J Clin Endocrinol Metab 87 8 2002 3997 4000 (Pubitemid 34879561)
28. T.K. Hansen, R. Dall, and H. Hosoda Weight loss increases circulating levels of ghrelin in human obesity Clin Endocrinol 56 2 2002 203 206 (Pubitemid 34233957)