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48
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Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells
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49
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Healing of incisional wounds in the embryonic chick wing bud: Characterization of the actin purse-string and demonstration of a requirement for rho activation
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0032489841
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A new member of the rho family, md1, promotes disassembly of actin filament structures and loss of cell adhesion
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of special interest. This study reports a new member of the Rho family of small GTPases that appears to play a role in regulating actin cytoskeleton organization and effects cell - cell adhesion
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Nobes CD, Lauritzen I, Mattei M-G, Paris S, Hall A, Chardin P. A new member of the rho family, md1, promotes disassembly of actin filament structures and loss of cell adhesion. of special interest J Cell Biol. 141:1998;187-197 This study reports a new member of the Rho family of small GTPases that appears to play a role in regulating actin cytoskeleton organization and effects cell - cell adhesion.
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Nobes, C.D.1
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Hall A. Rho GTPases and the actin cytoskeleton. of outstanding interest Science. 279:1998;509-513 A recent general review on functions of the RhoA family of small GTPases.
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Hall, A.1
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0032514214
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Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity
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of outstanding interest. Analysis of the role of RhoA and Rac1 on cell - cell adhesion and the development of cell polarity in MDCK epithelial cells
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Jou T-S, Nelson WJ. Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity. of outstanding interest J Cell Biol. 140:1998;85-100 Analysis of the role of RhoA and Rac1 on cell - cell adhesion and the development of cell polarity in MDCK epithelial cells.
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53
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Regulation of cell - Cell adhesion by rac and rho small G proteins in MDCK cells
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Takaishi K, Sasaki T, Kotani H, Nishioka H, Takai Y. Regulation of cell - cell adhesion by rac and rho small G proteins in MDCK cells. of outstanding interest J Cell Biol. 139:1997;1047-1059 This study describes the effects of expressing mutant RhoA and Rac1 on cell - cell adhesion and the actin cytoskeleton of MDCK cells.
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54
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0030968177
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The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts
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of outstanding interest. Detailed analysis of the effects of microinjecting mutant Rac1 and RhoA on actin cytoskeleton and cadherin cell - cell contacts in keratinocytes
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Braga VMM, Machesky LM, Hall A, Hotchin NA. The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. of outstanding interest J Cell Biol. 137:1997;1421-1431 Detailed analysis of the effects of microinjecting mutant Rac1 and RhoA on actin cytoskeleton and cadherin cell - cell contacts in keratinocytes.
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56
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A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes
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Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
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58
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60
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61
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0032493903
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Role of IQGAP1, a target of the small GTPases Cdc42 and fac1, in regulation of E-cadherin-mediated cell-cell adhesion
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of outstanding interest. A detailed study showing how IQGAP1 regulates assembly of the cadherin - catenin complex and cell - cell adhesion
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Kuroda S, Fukata M, Nakagawa M, Fujii K, Nakamura T, Ookuba T, Izawa I, Nagase T, Nomura N, Tani H, et al. Role of IQGAP1, a target of the small GTPases Cdc42 and fac1, in regulation of E-cadherin-mediated cell-cell adhesion. of outstanding interest Science. 281:1998;832-835 A detailed study showing how IQGAP1 regulates assembly of the cadherin - catenin complex and cell - cell adhesion.
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62
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0031017220
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Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure
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of outstanding interest. An important study showing mechanical linkages between integrin adhesion plaques, the cytoskeleton, and nuclear structures
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Maniotis AJ, Chen CS, Ingber DE. Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. of outstanding interest Proc Natl Acad Sci USA. 94:1997;849-854 An important study showing mechanical linkages between integrin adhesion plaques, the cytoskeleton, and nuclear structures.
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Maniotis, A.J.1
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0032563564
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Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high resolution tracking of E-cadherin/GFP
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of outstanding interest. The first detailed analysis of E-cadherin dynamics during cell - cell adhesion in living MDCK cells
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Adams CA, Smith SJ, Nelson WJ. Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high resolution tracking of E-cadherin/GFP. of outstanding interest J Cell Biol. 142:1998;1105-1119 The first detailed analysis of E-cadherin dynamics during cell - cell adhesion in living MDCK cells.
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Adams, C.A.1
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Nelson, W.J.3
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