Sidestream dark field imaging: The evolution of real-time visualization of cutaneous microcirculation and its potential application in dermatology

Archives of Dermatological Research

Volumn 303, Issue 2, 2011, Pages 69-78

  Treu, Curt M ^a   Lupi, Omar ^a   Bottino, Daniel A ^a   Bouskela, Eliete ^a  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Microcirculation; Nailfold videocapillaroscopy; Orthogonal polarization spectral imaging; Sidestream dark field imaging

Indexed keywords

ACCURACY; BLOOD FLOW; CONFOCAL LASER MICROSCOPY; ILLUMINATION; IMAGE ANALYSIS; IMAGE QUALITY; LASER DOPPLER FLOWMETRY; LIGHT EMITTING DIODE; MICROCIRCULATION; NON INVASIVE PROCEDURE; PRIORITY JOURNAL; REVIEW; SIDESTREAM DARK FIELD IMAGING; SKIN BLOOD FLOW;

ANIMALS; CAPILLARIES; DERMATOLOGY; DIAGNOSTIC IMAGING; HUMANS; LASER-DOPPLER FLOWMETRY; MICROCIRCULATION; MICROSCOPY, CONFOCAL; MICROSCOPY, VIDEO; SKIN;

EID: 79951978777     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00403-010-1087-7     Document Type: Review

References (68)

1. MA Altintas AA Altintas M Guggenheim, et al. 2010 Insight in human skin microcirculation using in vivo reflectance-mode confocal laser scanning microscopy J Digit Imaging 23 475 481 10.1007/s10278-009-9219-3 19513794
2. MA Altintas M Meyer-Marcotty AA Altintas, et al. 2009 In vivo reflectance-mode confocal microscopy provides insights in human skin microcirculation and histomorphology Comput Med Imaging Graph 33 532 536 1:STN:280:DC%2BD1Mrkt1Okug%3D%3D 10.1016/j.compmedimag.2009.04.011 19481421
3. G Argenziano I Zalaudek R Corona, et al. 2004 Vascular structures in skin tumors: a dermoscopy study Arch Dermatol 140 1485 1489 10.1001/archderm.140.12. 1485 15611426 (Pubitemid 39627440)
4. IM Braverman 2000 The cutaneous microcirculation J Investig Dermatol Symp Proc 5 3 9 1:STN:280:DC%2BD3M7jvVShsw%3D%3D 10.1046/j.1087-0024.2000.00010.x 11147672 (Pubitemid 32044082)
5. PH Carpentier 2001 Current techniques for the clinical evaluation of the microcirculation J Mal Vasc 26 142 147 1:STN:280:DC%2BD3M3ovVantQ%3D%3D 11319422 (Pubitemid 32416940)
6. V Cerny Z Turek R Parizkova 2007 Orthogonal polarization spectral imaging Physiol Res 56 141 147 1:STN:280:DC%2BD2s3psVKgsw%3D%3D 16555953
7. DS Coelho da Mota E Furtado DA Bottino, et al. 2009 Effects of buflomedil and pentoxifylline on hamster skin-flap microcirculation: prediction of flap viability using orthogonal polarization spectral imaging Clinics (Sao Paulo) 64 797 802
8. JL Cracowski CT Minson M Salvat-Melis, et al. 2006 Methodological issues in the assessment of skin microvascular endothelial function in humans Trends Pharmacol Sci 27 503 508 1:CAS:528:DC%2BD28XotlGktrs%3D 10.1016/j.tips.2006.07. 008 16876881 (Pubitemid 44233694)
9. M Cutolo C Pizzorni A Sulli 2005 Capillaroscopy Best Pract Res Clin Rheumatol 19 437 452 10.1016/j.berh.2005.01.001 15939368 (Pubitemid 40796531)
10. MA Dancour JL Vaz DA Bottino, et al. 2006 Nailfold videocapillaroscopy in patients with systemic lupus erythematosus Rheumatol Int 26 633 637 1:STN:280:DC%2BD283gtlehug%3D%3D 10.1007/s00296-005-0033-z 16180000
11. D De Backer J Creteur MJ Dubois, et al. 2006 The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects Crit Care Med 34 403 408 10.1097/01.CCM.0000198107.61493.5A 16424721 (Pubitemid 43145619)
12. CA Den Uil WK Lagrand EM van der Ent, et al. 2009 The effects of intra-aortic balloon pump support on macrocirculation and tissue microcirculation in patients with cardiogenic shock Cardiology 114 42 46 10.1159/000212060
13. CA Den Uil AP Maat WK Lagrand, et al. 2009 Mechanical circulatory support devices improve tissue perfusion in patients with end-stage heart failure or cardiogenic shock J Heart Lung Transpl 28 906 911 10.1016/j.healun.2009.05.010
14. JG Dobbe GJ Streekstra B Atasever, et al. 2008 Measurement of functional microcirculatory geometry and velocity distributions using automated image analysis Med Biol Eng Comput 46 659 670 1:STN:280:DC%2BD1czovFCquw%3D%3D 10.1007/s11517-008-0349-4 18427850
15. A Draisma R Bemelmans JG van der Hoeven, et al. 2009 Microcirculation and vascular reactivity during endotoxemia and endotoxin tolerance in humans Shock 31 581 585 10.1097/SHK.0b013e318193e187 19008780
16. MJ Dubois D De Backer J Creteur, et al. 2003 Effect of vasopressin on sublingual microcirculation in a patient with distributive shock Intensive Care Med 29 1020 1023 12736775 (Pubitemid 36783180)
17. PW Elbers A Ozdemir M van Iterson, et al. 2009 Microcirculatory imaging in cardiac anesthesia: ketanserin reduces blood pressure but not perfused capillary density J Cardiothorac Vasc Anesth 23 95 101 10.1053/j.jvca.2008.09. 013 19058975
18. CG Ellis ML Ellsworth RN Pittman, et al. 1992 Application of image analysis for evaluation of red blood cell dynamics in capillaries Microvasc Res 44 214 225 1:STN:280:DyaK3s7hs1Khuw%3D%3D 10.1016/0026-2862(92)90081-Y 1474928
19. A Erol-Yilmaz B Atasever K Mathura, et al. 2007 Cardiac resynchronization improves microcirculation J Cardiac Fail 13 95 99 10.1016/j.cardfail.2006.10. 016 (Pubitemid 46467391)
20. B Fagrell 1973 Vital capillary microscopy. A clinical method for studying changes of the nutritional skin capillaries in legs with arteriosclerosis obliterans Scand J Clin Lab Investig Suppl 133 2 50 1:STN:280: DyaE2c%2FmvVWhsQ%3D%3D
21. M Fries MH Weil YT Chang, et al. 2006 Microcirculation during cardiac arrest and resuscitation Crit Care Med 34 S454 S457 10.1097/01.CCM.0000247717. 81480.B2 17114977 (Pubitemid 44772681)
22. F Gallucci R Russo R Buono, et al. 2008 Indications and results of videocapillaroscopy in clinical practice Adv Med Sci 53 149 157 1:STN:280:DC%2BD1M7ktF2rtg%3D%3D 10.2478/v10039-008-0038-4 18842560
23. O Genzel-Boroviczeny J Strotgen AG Harris, et al. 2002 Orthogonal polarization spectral imaging (OPS): a novel method to measure the microcirculation in term and preterm infants transcutaneously Pediatr Res 51 386 391 10.1203/00006450-200203000-00019 11861946 (Pubitemid 34174977)
24. A Gerger S Koller W Weger, et al. 2006 Sensitivity and specificity of confocal laser-scanning microscopy for in vivo diagnosis of malignant skin tumors Cancer 107 193 200 10.1002/cncr.21910 16615102 (Pubitemid 43939047)
25. PT Goedhart M Khalilzada R Bezemer, et al. 2007 Sidestream dark field (SDF) imaging: a novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation Opt Express 15 15101 15114 1:STN:280:DC%2BD1MvktVWitw%3D%3D 10.1364/OE.15.015101 19550794 (Pubitemid 350127674)
26. O Goertz A Ring A Kohlinger, et al. 2010 Orthogonal polarization spectral imaging: a tool for assessing burn depths? Ann Plast Surg 64 217 221 1:CAS:528:DC%2BC3cXpsVegsg%3D%3D 10.1097/SAP.0b013e3181a1473b 20098109
27. S Gonzalez K Swindells M Rajadhyaksha, et al. 2003 Changing paradigms in dermatology: confocal microscopy in clinical and surgical dermatology Clin Dermatol 21 359 369 10.1016/j.clindermatol.2003.08.007 14678715 (Pubitemid 37543551)
28. W Groner JW Winkelman AG Harris, et al. 1999 Orthogonal polarization spectral imaging: a new method for study of the microcirculation Nat Med 5 1209 1212 1:CAS:528:DyaK1MXms1Wkt7s%3D 10.1038/13529 10502828 (Pubitemid 29474429)
29. VL Halfoun ML Pires TJ Fernandes, et al. 2003 Videocapillaroscopy and diabetes mellitus: area of transverse segment in nailfold capillary loops reflects vascular reactivity Diabetes Res Clin Pract 61 155 160 1:STN:280:DC%2BD3svisVyksA%3D%3D 10.1016/S0168-8227(03)00111-6 12965104 (Pubitemid 37083509)
30. AG Harris I Sinitsina K Messmer 2000 The Cytoscan Model E-II, a new reflectance microscope for intravital microscopy: comparison with the standard fluorescence method J Vasc Res 37 469 476 1:STN:280:DC%2BD3M7hvFalsQ%3D%3D 10.1159/000054079 11146400 (Pubitemid 32037621)
31. S Hiedl A Schwepcke F Weber, et al. 2010 Microcirculation in preterm infants: profound effects of patent ductus arteriosus J Pediatr 156 191 196 10.1016/j.jpeds.2009.08.034 19846115
32. Ince C (2005) The microcirculation is the motor of sepsis. Crit Care 9(Suppl 4):S13-S19 (Pubitemid 41498527)
33. G Jorneskog K Brismar B Fagrell 1998 Pronounced skin capillary ischemia in the feet of diabetic patients with bad metabolic control Diabetologia 41 410 415 1:STN:280:DyaK1c3itVyitg%3D%3D 10.1007/s001250050923 9562344 (Pubitemid 28157411)
34. C Jung M Ferrari R Gradinger, et al. 2008 Evaluation of the microcirculation during extracorporeal membrane-oxygenation Clin Hemorheol Microcirc 40 311 314 19126994
35. E Klijn CA Den Uil J Bakker, et al. 2008 The heterogeneity of the microcirculation in critical illness Clin Chest Med 29 643 654 10.1016/j.ccm.2008.06.008 18954699
36. T Klyscz M Junger F Jung, et al. 1997 Cap image-a new kind of computer-assisted video image analysis system for dynamic capillary microscopy Biomed Tech (Berl) 42 168 175 1:STN:280:DyaK2szovFOmtQ%3D%3D 10.1515/bmte.1997.42.6.168
37. M Koch D De Backer JL Vincent, et al. 2008 Effects of propofol on human microcirculation Br J Anaesth 101 473 478 1:CAS:528:DC%2BD1cXhtFWhsrbJ 10.1093/bja/aen210 18653494
38. LG Kraemer-Aguiar CM Laflor E Bouskela 2008 Skin microcirculatory dysfunction is already present in normoglycemic subjects with metabolic syndrome Metabolism 57 1740 1746 1:CAS:528:DC%2BD1cXhtlyktrzL 10.1016/j.metabol.2008.07. 034 19013299
39. J Kroth K Weidlich S Hiedl, et al. 2008 Functional vessel density in the first month of life in preterm neonates Pediatr Res 64 567 571 10.1203/PDR.0b013e318184134e 18596573
40. S Kubli B Waeber A le-Ave, et al. 2000 Reproducibility of laser Doppler imaging of skin blood flow as a tool to assess endothelial function J Cardiovasc Pharmacol 36 640 648 1:CAS:528:DC%2BD3cXnslKjsL4%3D 10.1097/00005344-200011000- 00014 11065225
41. L La Civita M Rossi G Vagheggini, et al. 1998 Microvascular involvement in systemic sclerosis: laser Doppler evaluation of reactivity to acetylcholine and sodium nitroprusside by iontophoresis Ann Rheum Dis 57 52 55 10.1136/ard.57.1.52 9536825 (Pubitemid 28175222)
42. K Lam KD Sjauw JP Henriques, et al. 2009 Improved microcirculation in patients with an acute ST-elevation myocardial infarction treated with the Impella LP2.5 percutaneous left ventricular assist device Clin Res Cardiol 98 311 318 10.1007/s00392-009-0006-4 19280085
43. S Langer R Hatz AG Harris, et al. 2001 Assessing the microcirculation in a burn wound by use of OPS imaging Eur J Med Res 6 231 234 1:STN:280: DC%2BD3Mzns1GqtA%3D%3D 11432795
44. CL Lascasas-Porto AL Milhomens CE Virgini-Magalhaes, et al. 2008 Use of microcirculatory parameters to evaluate clinical treatments of chronic venous disorder (CVD) Microvasc Res 76 66 72 10.1016/j.mvr.2008.02.002 18423497
45. L Lindbom RF Tuma KE Arfors 1982 Blood flow in the rabbit tenuissimus muscle. Influence of preparative procedures for intravital microscopic observation Acta Physiol Scand 114 121 127 1:STN:280:DyaL3s%2FksVOhsA%3D%3D 10.1111/j.1748-1716.1982.tb06960.x 7136740 (Pubitemid 12184060)
46. J Lindert J Werner M Redlin, et al. 2002 OPS imaging of human microcirculation: a short technical report J Vasc Res 39 368 372 1:STN:280:DC%2BD38vjtVCksg%3D%3D 10.1159/000065549 12187127 (Pubitemid 34983868)
47. O Lupi I Semenovitch C Treu, et al. 2008 Orthogonal polarization technique in the assessment of human skin microcirculation Int J Dermatol 47 425 431 10.1111/j.1365-4632.2008.03694.x 18412856 (Pubitemid 351560304)
48. O Lupi IJ Semenovitch C Treu, et al. 2007 Evaluation of the effects of caffeine in the microcirculation and edema on thighs and buttocks using the orthogonal polarization spectral imaging and clinical parameters J Cosmet Dermatol 6 102 107 10.1111/j.1473-2165.2007.00304.x 17524126 (Pubitemid 46845419)
49. HR Maricq JA Downey EC LeRoy 1976 Standstill of nailfold capillary blood flow during cooling in scleroderma and Raynaud's syndrome Blood Vessels 13 338 349 1:STN:280:DyaE2s7ht1yqtw%3D%3D 1016736 (Pubitemid 8021038)
50. HR Maricq G Spencer-Green EC LeRoy 1976 Skin capillary abnormalities as indicators of organ involvement in scleroderma (systemic sclerosis), Raynaud's syndrome and dermatomyositis Am J Med 61 862 870 1:STN:280: DyaE2s%2FosFSlsA%3D%3D 10.1016/0002-9343(76)90410-1 1008072 (Pubitemid 8007446)
51. DS Martin C Ince P Goedhart, et al. 2009 Abnormal blood flow in the sublingual microcirculation at high altitude Eur J Appl Physiol 106 473 478 10.1007/s00421-009-1023-8 19333616
52. KR Mathura KC Vollebregt K Boer, et al. 2001 Comparison of OPS imaging and conventional capillary microscopy to study the human microcirculation J Appl Physiol 91 74 78 1:STN:280:DC%2BD3MzksFCrsQ%3D%3D 11408415 (Pubitemid 32574710)
53. DM Milstein R Bezemer JA Lindeboom, et al. 2009 The acute effects of CMF-based chemotherapy on maxillary periodontal microcirculation Cancer Chemother Pharmacol 64 1047 1052 1:CAS:528:DC%2BD1MXhtVSitL3L 10.1007/s00280-009-1082-x 19633849
54. A Nencioni S Trzeciak NI Shapiro 2009 The microcirculation as a diagnostic and therapeutic target in sepsis Intern Emerg Med 4 413 415 10.1007/s11739-009-0297-5 19707845
55. M Nieuwdorp HL Mooij J Kroon, et al. 2006 Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes Diabetes 55 1127 1132 1:CAS:528:DC%2BD28XjsVGmtbc%3D 10.2337/diabetes.55.04.06.db05-1619 16567538 (Pubitemid 44100191)
56. P Nivoit N Wiernsperger P Moulin, et al. 2003 Effect of glycated LDL on microvascular tone in mice: a comparative study with LDL modified in vitro or isolated from diabetic patients Diabetologia 46 1550 1558 1:CAS:528: DC%2BD3sXptVyqsL4%3D 10.1007/s00125-003-1225-2 14576982 (Pubitemid 37518576)
57. Y Pan AJ Chamberlain M Bailey, et al. 2008 Dermatoscopy aids in the diagnosis of the solitary red scaly patch or plaque-features distinguishing superficial basal cell carcinoma, intraepidermal carcinoma, and psoriasis J Am Acad Dermatol 59 268 274 10.1016/j.jaad.2008.05.013 18550207
58. T Scholz GR Evans 2008 Flap microcirculation: effects of tissue manipulation and in situ preparation during soft tissue harvest J Reconstr Microsurg 24 277 283 10.1055/s-2008-1078694 18496778 (Pubitemid 351976939)
59. MP Schon WH Boehncke 2005 Psoriasis N Engl J Med 352 1899 1912 1:CAS:528:DC%2BD2MXjvVegsLY%3D 10.1056/NEJMra041320 15872205 (Pubitemid 40627816)
60. DW Slaaf GJ Tangelder RS Reneman, et al. 1987 A versatile incident illuminator for intravital microscopy Int J Microcirc Clin Exp 6 391 397 1:STN:280:DyaL1c7hsVemsg%3D%3D 3429145
61. N Steeghs H Gelderblom JO Roodt, et al. 2008 Hypertension and rarefaction during treatment with telatinib, a small molecule angiogenesis inhibitor Clin Cancer Res 14 3470 3476 1:CAS:528:DC%2BD1cXmslygtr8%3D 10.1158/1078-0432.CCR-07- 5050 18519779
62. G Stinco S Lautieri F Piccirillo, et al. 2009 Response of cutaneous microcirculation to treatment with mometasone furoate in patients with psoriasis Clin Exp Dermatol 34 915 919 1:STN:280:DC%2BC3c%2FhtVCrsA%3D%3D 10.1111/j.1365-2230.2009.03298.x 19486040
63. AE Taylor T Moore P Paisley 2002 The time has finally arrived: use of intravital microscopy in the airway circulation Am J Physiol Lung Cell Mol Physiol 282 L957 L958 1:CAS:528:DC%2BD38XjslWktrc%3D 11943659
64. I Tritto G Ambrosio 1999 Spotlight on microcirculation: an update Cardiovasc Res 42 600 606 1:CAS:528:DyaK1MXjs1Sjtbk%3D 10.1016/S0008-6363(99) 00020-6 10533599 (Pubitemid 29298128)
65. P Vajkoczy A Ullrich MD Menger 2000 Intravital fluorescence videomicroscopy to study tumor angiogenesis and microcirculation Neoplasia 2 53 61 1:STN:280:DC%2BD3cvhvFKqsQ%3D%3D 10.1038/sj.neo.7900062 10933068 (Pubitemid 30123180)
66. JL Vaz MA Dancour DA Bottino, et al. 2004 Nailfold videocapillaroscopy in primary antiphospholipid syndrome (PAPS) Rheumatology (Oxford) 43 1025 1027 1:STN:280:DC%2BD2czlsFOrsg%3D%3D 10.1093/rheumatology/keh233 (Pubitemid 39144450)
67. CE Virgini-Magalhaes CL Porto FF Fernandes, et al. 2006 Use of microcirculatory parameters to evaluate chronic venous insufficiency J Vasc Surg 43 1037 1044 10.1016/j.jvs.2005.12.065 16678701
68. Weidlich K, Kroth J, Hiedl CN et al (2009) Changes in microcirculation as early markers for infection in preterm infants-an observational prospective study. Pediatr Res 66(4):461-465