-
1
-
-
0034008116
-
Microcirculatory dysfunction in sepsis: A pathogenetic basis for therapy?
-
Lehr HA, Bittinger F, Kirkpatrick CJ (2000) Microcirculatory dysfunction in sepsis: a pathogenetic basis for therapy? J Pathol 190: 373-386.
-
(2000)
J Pathol
, vol.190
, pp. 373-386
-
-
Lehr, H.A.1
Bittinger, F.2
Kirkpatrick, C.J.3
-
2
-
-
19944406420
-
Whole blood and leukocyte RNA isolation for gene expression analyses
-
Feezor RJ, Baker HV, Mindrinos M et al (2004) Whole blood and leukocyte RNA isolation for gene expression analyses. Physiol Genom 19: 247-254.
-
(2004)
Physiol Genom
, vol.19
, pp. 247-254
-
-
Feezor, R.J.1
Baker, H.V.2
Mindrinos, M.3
-
3
-
-
0028053865
-
Microvascular perfusion is impaired in a rat model of normotensive sepsis
-
Lam C, Tyml K, Martin C, Sibbald W (1994) Microvascular perfusion is impaired in a rat model of normotensive sepsis. J Clin Invest 94: 2077-2083.
-
(1994)
J Clin Invest
, vol.94
, pp. 2077-2083
-
-
Lam, C.1
Tyml, K.2
Martin, C.3
Sibbald, W.4
-
4
-
-
33751094014
-
Comparison of buccal microcirculation between septic and hemorrhagic shock
-
Fang X, Tang W, Sun S et al (2006) Comparison of buccal microcirculation between septic and hemorrhagic shock. Crit Care Med 34(12 Suppl): S447-S453.
-
(2006)
Crit Care Med
, vol.34
, Issue.12 SUPPL.
-
-
Fang, X.1
Tang, W.2
Sun, S.3
-
5
-
-
33845872563
-
Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: Relationship to hemodynamics, oxygen transport, and survival
-
98.e1-2
-
Trzeciak S, Dellinger RP, Parrillo JE et al (2007) Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival. Ann Emerg Med 49: 88-98 98. e1-2.
-
(2007)
Ann Emerg Med
, vol.49
, pp. 88-98
-
-
Trzeciak, S.1
Dellinger, R.P.2
Parrillo, J.E.3
-
6
-
-
0027415523
-
Unreliability of blood pressure and heart rate to evaluate cardiac output in emergency resuscitation and critical illness
-
Wo CC, Shoemaker WC, Appel PL, Bishop MH, Kram HB, Hardin E (1993) Unreliability of blood pressure and heart rate to evaluate cardiac output in emergency resuscitation and critical illness. Crit Care Med 21: 218-223.
-
(1993)
Crit Care Med
, vol.21
, pp. 218-223
-
-
Wo, C.C.1
Shoemaker, W.C.2
Appel, P.L.3
Bishop, M.H.4
Kram, H.B.5
Hardin, E.6
-
7
-
-
0037323947
-
Empirical antimicrobial therapy of septic shock patients: Adequacy and impact on the outcome
-
Leone M, Bourgoin A, Cambon S, Dubuc M, Albanese J, Martin C (2003) Empirical antimicrobial therapy of septic shock patients: adequacy and impact on the outcome. Crit Care Med 31: 462-467.
-
(2003)
Crit Care Med
, vol.31
, pp. 462-467
-
-
Leone, M.1
Bourgoin, A.2
Cambon, S.3
Dubuc, M.4
Albanese, J.5
Martin, C.6
-
8
-
-
4444233598
-
Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock
-
Sakr Y, Dubois MJ, De Backer D, Creteur J, Vincent JL (2004) Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med 32: 1825-1831.
-
(2004)
Crit Care Med
, vol.32
, pp. 1825-1831
-
-
Sakr, Y.1
Dubois, M.J.2
de Backer, D.3
Creteur, J.4
Vincent, J.L.5
-
9
-
-
0036644655
-
Microvascular blood flow is altered in patients with sepsis
-
De Backer D, Creteur J, Preiser JC, Dubois MJ, Vincent JL (2002) Microvascular blood flow is altered in patients with sepsis. Am J Respir Crit Care Med 166: 98-104.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 98-104
-
-
de Backer, D.1
Creteur, J.2
Preiser, J.C.3
Dubois, M.J.4
Vincent, J.L.5
-
11
-
-
0034039670
-
Microvascular response in patients with cardiogenic shock
-
Kirschenbaum LA, Astiz ME, Rackow EC, Saha DC, Lin R (2000) Microvascular response in patients with cardiogenic shock. Crit Care Med 28: 1290-1294.
-
(2000)
Crit Care Med
, vol.28
, pp. 1290-1294
-
-
Kirschenbaum, L.A.1
Astiz, M.E.2
Rackow, E.C.3
Saha, D.C.4
Lin, R.5
-
12
-
-
20644467056
-
How monitoring of the microcirculation may help us at the bedside
-
Verdant C, De Backer D (2005) How monitoring of the microcirculation may help us at the bedside. Curr Opin Crit Care 11: 240-244.
-
(2005)
Curr Opin Crit Care
, vol.11
, pp. 240-244
-
-
Verdant, C.1
de backer, D.2
-
13
-
-
27144553471
-
The microcirculation is the motor of sepsis
-
Ince C (2005) The microcirculation is the motor of sepsis. Crit Care 9(Suppl 4): S13-S19.
-
(2005)
Crit Care
, vol.9
, Issue.SUPPL. 4
-
-
Ince, C.1
-
14
-
-
0036375463
-
OPS imaging of human microcirculation: A short technical report
-
Lindert J, Werner J, Redlin M, Kuppe H, Habazettl H, Pries AR (2002) OPS imaging of human microcirculation: a short technical report. J Vasc Res 39: 368-372.
-
(2002)
J Vasc Res
, vol.39
, pp. 368-372
-
-
Lindert, J.1
Werner, J.2
Redlin, M.3
Kuppe, H.4
Habazettl, H.5
Pries, A.R.6
-
15
-
-
0034831025
-
Sublingual capnography: A clinical validation study
-
Marik PE (2001) Sublingual capnography: a clinical validation study. Chest 120: 923-927.
-
(2001)
Chest
, vol.120
, pp. 923-927
-
-
Marik, P.E.1
-
17
-
-
34247171377
-
Relationship between sublingual and intestinal microcirculatory perfusion in patients with abdominal sepsis
-
Boerma EC, van der Voort PH, Spronk PE, Ince C (2007) Relationship between sublingual and intestinal microcirculatory perfusion in patients with abdominal sepsis. Crit Care Med 35: 1055-1060.
-
(2007)
Crit Care Med
, vol.35
, pp. 1055-1060
-
-
Boerma, E.C.1
van der Voort, P.H.2
Spronk, P.E.3
Ince, C.4
-
18
-
-
0035829842
-
Early goal-directed therapy in the treatment of severe sepsis and septic shock
-
Rivers E, Nguyen B, Havstad S et al (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345: 1368-1377.
-
(2001)
N Engl J Med
, vol.345
, pp. 1368-1377
-
-
Rivers, E.1
Nguyen, B.2
Havstad, S.3
-
19
-
-
0141920370
-
Bench-to-bedside review: Microvascular dysfunction in sepsis-hemodynamics, oxygen transport, and nitric oxide
-
Bateman RM, Sharpe MD, Ellis CG (2003) Bench-to-bedside review: microvascular dysfunction in sepsis-hemodynamics, oxygen transport, and nitric oxide. Crit Care 7: 359-373.
-
(2003)
Crit Care
, vol.7
, pp. 359-373
-
-
Bateman, R.M.1
Sharpe, M.D.2
Ellis, C.G.3
-
20
-
-
34249083324
-
Mechanisms of critical illness-classifying microcirculatory flow abnormalities in distributive shock
-
Elbers PW, Ince C (2006) Mechanisms of critical illness-classifying microcirculatory flow abnormalities in distributive shock. Crit Care 10: 221.
-
(2006)
Crit Care
, vol.10
, pp. 221
-
-
Elbers, P.W.1
Ince, C.2
-
21
-
-
33745603201
-
Effects of drotrecogin alfa activated on microcirculatory alterations in patients with severe sepsis
-
De Backer D, Verdant C, Chierego M, Koch M, Gullo A, Vincent JL (2006) Effects of drotrecogin alfa activated on microcirculatory alterations in patients with severe sepsis. Crit Care Med 34: 1918-1924.
-
(2006)
Crit Care Med
, vol.34
, pp. 1918-1924
-
-
de Backer, D.1
Verdant, C.2
Chierego, M.3
Koch, M.4
Gullo, A.5
Vincent, J.L.6
-
22
-
-
0034647013
-
Increased microvascular reactivity and improved mortality in septic mice lacking inducible nitric oxide synthase
-
Hollenberg SM, Broussard M, Osman J, Parrillo JE (2000) Increased microvascular reactivity and improved mortality in septic mice lacking inducible nitric oxide synthase. Circ Res 86: 774-778.
-
(2000)
Circ Res
, vol.86
, pp. 774-778
-
-
Hollenberg, S.M.1
Broussard, M.2
Osman, J.3
Parrillo, J.E.4
-
23
-
-
0028359689
-
Nitric oxide synthase inhibition aggravates intestinal microvascular vasoconstriction and hypoperfusion of bacteremia
-
Spain DA, Wilson MA, Bar-Natan MF, Garrison RN (1994) Nitric oxide synthase inhibition aggravates intestinal microvascular vasoconstriction and hypoperfusion of bacteremia. J Trauma 36: 720-725.
-
(1994)
J Trauma
, vol.36
, pp. 720-725
-
-
Spain, D.A.1
Wilson, M.A.2
Bar-natan, M.F.3
Garrison, R.N.4
-
24
-
-
44049093984
-
Resuscitating the microcirculation in sepsis: The central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials
-
Trzeciak S, Cinel I, Phillip Dellinger R et al (2008) Resuscitating the microcirculation in sepsis: the central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials. Acad Emerg Med 15: 399-413.
-
(2008)
Acad Emerg Med
, vol.15
, pp. 399-413
-
-
Trzeciak, S.1
Cinel, I.2
Phillip Dellinger, R.3
-
25
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard GR, Vincent JL, Laterre PF et al (2001) Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 344: 699-709.
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
-
26
-
-
0031648469
-
The nitric oxide donor sodium nitroprusside protects against hepatic microcirculatory dysfunction in early endotoxaemia
-
Gundersen Y, Corso CO, Leiderer R et al (1998) The nitric oxide donor sodium nitroprusside protects against hepatic microcirculatory dysfunction in early endotoxaemia. Intensive Care Med 24: 1257-1263.
-
(1998)
Intensive Care Med
, vol.24
, pp. 1257-1263
-
-
Gundersen, Y.1
Corso, C.O.2
Leiderer, R.3
-
27
-
-
38349195638
-
Effects of sodium nitroprusside on splanchnic microcirculation in a resuscitated porcine model of septic shock
-
Assadi A, Desebbe O, Kaminski C et al (2008) Effects of sodium nitroprusside on splanchnic microcirculation in a resuscitated porcine model of septic shock. Br J Anaesth 100: 55-65.
-
(2008)
Br J Anaesth
, vol.100
, pp. 55-65
-
-
Assadi, A.1
Desebbe, O.2
Kaminski, C.3
-
28
-
-
0037010370
-
Nitroglycerin in septic shock after intravascular volume resuscitation
-
Spronk PE, Ince C, Gardien MJ, Mathura KR, Oudemans-van Straaten HM, Zandstra DF (2002) Nitroglycerin in septic shock after intravascular volume resuscitation. Lancet 360(9343): 1395-1396.
-
(2002)
Lancet
, vol.360
, Issue.9343
, pp. 1395-1396
-
-
Spronk, P.E.1
Ince, C.2
Gardien, M.J.3
Mathura, K.R.4
Oudemans-van Straaten, H.M.5
Zandstra, D.F.6
-
29
-
-
0036039753
-
Opening the microcirculation: Can vasodilators be useful in sepsis?
-
Buwalda M, Ince C (2002) Opening the microcirculation: can vasodilators be useful in sepsis? Intensive Care Med 28: 1208-1217.
-
(2002)
Intensive Care Med
, vol.28
, pp. 1208-1217
-
-
Buwalda, M.1
Ince, C.2
-
30
-
-
0038047593
-
Effects of dopamine, norepinephrine, and epinephrine on the splanchnic circulation in septic shock: Which is best?
-
De Backer D, Creteur J, Silva E, Vincent JL (2003) Effects of dopamine, norepinephrine, and epinephrine on the splanchnic circulation in septic shock: which is best? Crit Care Med 31: 1659-1667.
-
(2003)
Crit Care Med
, vol.31
, pp. 1659-1667
-
-
de Backer, D.1
Creteur, J.2
Silva, E.3
Vincent, J.L.4
-
31
-
-
0036124322
-
Dobutamine and gastric-to-arterial carbon dioxide gap in severe sepsis without shock
-
Lebuffe G, Levy B, Neviere R et al (2002) Dobutamine and gastric-to-arterial carbon dioxide gap in severe sepsis without shock. Intensive Care Med 28: 265-271.
-
(2002)
Intensive Care Med
, vol.28
, pp. 265-271
-
-
Lebuffe, G.1
Levy, B.2
Neviere, R.3
-
32
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard GR, Vincent JL, Laterre PF et al (2001) Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 344: 699-709.
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
-
33
-
-
25444492831
-
Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death
-
Abraham E, Laterre PF, Garg R et al (2005) Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death. N Engl J Med 353: 1332-1341.
-
(2005)
N Engl J Med
, vol.353
, pp. 1332-1341
-
-
Abraham, E.1
Laterre, P.F.2
Garg, R.3
-
34
-
-
1842637573
-
Microhemodynamic and cellular mechanisms of activated protein C action during endotoxemia
-
Hoffmann JN, Vollmar B, Laschke MW et al (2004) Microhemodynamic and cellular mechanisms of activated protein C action during endotoxemia. Crit Care Med 32: 1011-1017.
-
(2004)
Crit Care Med
, vol.32
, pp. 1011-1017
-
-
Hoffmann, J.N.1
Vollmar, B.2
Laschke, M.W.3
-
35
-
-
13444303827
-
Activated protein C improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat lipopolysaccharide model
-
Iba T, Kidokoro A, Fukunaga M, Nagakari K, Shirahama A, Ida Y (2005) Activated protein C improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat lipopolysaccharide model. Crit Care Med 33: 368-372.
-
(2005)
Crit Care Med
, vol.33
, pp. 368-372
-
-
Iba, T.1
Kidokoro, A.2
Fukunaga, M.3
Nagakari, K.4
Shirahama, A.5
Ida, Y.6
-
36
-
-
34249083323
-
Activated protein C improves intestinal microcirculation in experimental endotoxaemia in the rat
-
Lehmann C, Meissner K, Knock A et al (2006) Activated protein C improves intestinal microcirculation in experimental endotoxaemia in the rat. Crit Care 10: R157.
-
(2006)
Crit Care
, vol.10
-
-
Lehmann, C.1
Meissner, K.2
Knock, A.3
-
37
-
-
0032185422
-
Selective gut microcirculatory control (SGMC) in septic rats: A novel approach with a locally applied vasoactive drug
-
Hersch M, Madorin WS, Sibbald WJ, Martin CM (1998) Selective gut microcirculatory control (SGMC) in septic rats: a novel approach with a locally applied vasoactive drug. Shock 10: 292-297.
-
(1998)
Shock
, vol.10
, pp. 292-297
-
-
Hersch, M.1
Madorin, W.S.2
Sibbald, W.J.3
Martin, C.M.4
-
38
-
-
23644461209
-
Intensive insulin therapy protects the endothelium of critically ill patients
-
Langouche L, Vanhorebeek I, Vlasselaers D et al (2005) Intensive insulin therapy protects the endothelium of critically ill patients. J Clin Invest 115: 2277-2286.
-
(2005)
J Clin Invest
, vol.115
, pp. 2277-2286
-
-
Langouche, L.1
Vanhorebeek, I.2
Vlasselaers, D.3
-
39
-
-
33847729386
-
Beneficial effects of statins on the microcirculation during sepsis: The role of nitric oxide
-
McGown CC, Brookes ZL (2007) Beneficial effects of statins on the microcirculation during sepsis: the role of nitric oxide. Br J Anaesth 98: 163-175.
-
(2007)
Br J Anaesth
, vol.98
, pp. 163-175
-
-
McGown, C.C.1
Brookes, Z.L.2
-
40
-
-
0037253077
-
Sigurdsson GH: Endothelin receptor antagonist bosentan improves microcirculatory blood flow in splanchnic organs in septic shock
-
Krejci V, Hiltebrand LB, Erni D (2003) Sigurdsson GH: Endothelin receptor antagonist bosentan improves microcirculatory blood flow in splanchnic organs in septic shock. Crit Care Med 31: 203-210.
-
(2003)
Crit Care Med
, vol.31
, pp. 203-210
-
-
Krejci, V.1
Hiltebrand, L.B.2
Erni, D.3
-
41
-
-
34447623219
-
Bench-to-bedside review: Potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure
-
Protti A, Singer M (2006) Bench-to-bedside review: potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure. Crit Care 10: 228.
-
(2006)
Crit Care
, vol.10
, pp. 228
-
-
Protti, A.1
Singer, M.2
-
42
-
-
0038271638
-
Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts
-
Stump CS, Short KR, Bigelow ML, Schimke JM, Nair KS (2003) Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts. Proc Natl Acad Sci USA 100: 7996-8001.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7996-8001
-
-
Stump, C.S.1
Short, K.R.2
Bigelow, M.L.3
Schimke, J.M.4
Nair, K.S.5
-
43
-
-
0032560572
-
Persistent inhibition of cell respiration by nitric oxide: Crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione
-
Clementi E, Brown GC, Feelisch M, Moncada S (1998) Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione. Proc Natl Acad Sci USA 95: 7631-7636.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 7631-7636
-
-
Clementi, E.1
Brown, G.C.2
Feelisch, M.3
Moncada, S.4
-
44
-
-
56849098444
-
A prospective, observational study of soluble Flt-1 and vascular endothelial growth factor in sepsis
-
[publish ahead of print]
-
Shapiro NI, Yano K, Okada H et al (2007) A prospective, observational study of soluble Flt-1 and vascular endothelial growth factor in sepsis. Shock [publish ahead of print].
-
(2007)
Shock
-
-
Shapiro, N.I.1
Yano, K.2
Okada, H.3
|