Sensitivity and specificity of confocal laser-scanning microscopy for in vivo diagnosis of malignant skin tumors

Cancer

Volumn 107, Issue 1, 2006, Pages 193-200

  Gerger, Armin ^a   Koller, Silvia ^a   Weger, Wolfgang ^a   Richtig, Erika ^a   Kerl, Helmut ^a   Samonigg, Hellmut ^a   Krippl, Peter ^a   Smolle, Josef ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Basal cell carcinoma; Confocal laser scanning microscopy; Malignant melanoma; Sensitivity; Specificity

Indexed keywords

ARTICLE; BASAL CELL CARCINOMA; CAUCASIAN; CONFOCAL LASER MICROSCOPY; DEVICE; EARLY DIAGNOSIS; FEMALE; HISTOPATHOLOGY; HUMAN; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; MELANOMA; NEVUS; OBSERVER VARIATION; PREDICTIVE VALIDITY; PRIORITY JOURNAL; SEBORRHEIC KERATOSIS; SENSITIVITY AND SPECIFICITY; SKIN CANCER; STATISTICAL ANALYSIS;

CARCINOMA, BASAL CELL; FEMALE; HUMANS; MALE; MELANOMA; MICROSCOPY, CONFOCAL; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; SKIN NEOPLASMS;

EID: 33745295456     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.21910     Document Type: Article

References (20)

1. Grin CM, Kopf AW, Welkovich B, Barr RS, Levenstein MJ. Accuracy in the clinical diagnosis of malignant melanoma. Arch Dermatol. 1990;126:763-766.
2. Ruocco E, Argenziano G, Pellacani G, Seideenari S. Noninvasive imaging of skin tumors. Dermatol Surg. 2004;30:301-310.
3. Braun RP, Rabinovitz HS, Oliviero M, Kopf AW, Saurat JH. Dermoscopy of pigmented skin lesions. J Am Acad Dermatol. 2005;52:109-121.
4. Bafounta ML, Beauchet A, Aegerter P, Saiag P. Is dermoscopy (epiluminescence microscopy) useful for the diagnosis of melanoma? Results of a meta-analysis using techniques adapted to the evaluation of diagnostic rests. Arch Dermatol. 2001;137:1343-1350.
5. Kittler H, Pehamberger H, Wolff K, Binder M. Diagnostic accuracy of dermoscopy. Lancet Oncol. 2002;3:159-165.
6. Rajadhyaksha M, Grossman M, Esterowitz D, Webb RH, Anderson RR. In vivo confocal scanning laser microscopy of human skin: melanin provides strong contrast. J Invest Dermatol 1995;104:946-952.
7. Rajadhyaksha M, Gonzalez S, Zavislan JM, Anderson RR, Webb RH. In vivo confocal scanning laser microscopy of human skin II: advances in instrumentation and comparison with histology. J Invest Dermatol. 1999;113:293-303.
8. Busam KJ, Charles C, Lee G, Halpern AC. Morphologic features of melanocytes, pigmented keratinocytes and melanophages by in vivo confocal scanning laser microscopy (CLSM). Mod Pathol. 2001;14:862-868.
9. Busam KJ, Charles C, Lohmann CM, Marghoob A, Goldgeier M, Halpern AC. Detection of intraepidermal malignant melanoma in vivo by confocal scanning laser microscopy. Melanoma Res. 2001;12:349-355.
10. Langley RG, Rajadhyaksha M, Dwyer PJ, Sober AJ, Flotte TJ, Anderson RR. Confocal scanning laser microscopy of benign and malignant skin lesions in vivo. J Am Acad Dermatol. 2001;45:365-376.
11. Gonzalez S, Tannous Z. Real-time, in vivo confocal reflectance microscopy of basal cell carcinoma. J Am Acad Dermatol. 2002;47:869-874.
12. Goldgeier M, Fox C, Zavislan J, Harris D, Gonzalez S. Non-invasive imaging, treatment, and microscopic confirmation of clearance of basal cell carcinoma. J Dermatol Surg. 2003; 29:205-210.
13. Curiel-Lewandrowski C, Williams C, Swindells K, et al. Use of in vivo confocal microscopy in malignant melanoma. Arch Dermatol. 2004;140:1127-1132.
14. Pellcacani G, Cesinaro A, Seidenari S. Reflectance-mode confocal microscopy for the in vivo characterization of pagetoid melanocytosis in melanomas and nevi. J Invest Dermatol. 2005;125:532-537.
15. Nori S, Rius-Diaz F, Cuevas J, et al. Sensitivity and specificity of reflectance-mode confocal microscopy for in vivo diagnosis of basal cell carcinoma: a multicenter study. J Am Acad Dermatol. 2004;51:923-930.
16. Gerger A, Koller S, Kern T, et al. Diagnostic applicability of in vivo confocal laser scanning microscopy in melanocytic skin tumors. J Invest Dermatol. 2005;24:493-498.
17. Steiner A, Pehamberger H, Wolff K. In vivo epiluminescence microscopy of pigmented skin lesions. II. Diagnosis of small pigmented skin lesions and early detection of malignant melanoma. J Am Acad Dermatol. 1987;17:584-591.
18. Pehamberger H, Steiner A, Wolff K. In vivo epiluminescence microscopy of pigmented skin lesions. I. Pattern analysis of pigmented skin lesions. J Am Acad Dermatol. 1987;17:571-583.
19. Lever WF, Schaumburg-Lever G. Histopathology of the Skin. Philadelphia: JB Lippincott; 1983.
20. Steinberg D, Colla P. CART. Tree-Structured Non-Parametric Data Analysis. San Diego: Salford Systems; 1995.