A gain-of-function screen identifies wdb and lkb1 as lifespan-extending genes in Drosophila

Biochemical and Biophysical Research Communications

Volumn 405, Issue 4, 2011, Pages 667-672

  Funakoshi, Masabumi ^a   Tsuda, Manabu ^a   Muramatsu, Keigo ^a   Hatsuda, Hiroshi ^b   Morishita, Shinichi ^b   Aigaki, Toshiro ^a  

^a TOKYO METROPOLITAN UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Drosophila; Gain of function screen; Lifespan extension; Organ size

Indexed keywords

ADENYLATE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; S6 KINASE; SOMATOMEDIN; TARGET OF RAPAMYCIN KINASE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA; FEMALE; GENE; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENETIC SCREENING; LIFESPAN; LKB1 GENE; MALE; NONHUMAN; ORGAN SIZE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WDB GENE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; LONGEVITY; ORGAN SIZE; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; WING;

EID: 79951952916     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.01.090     Document Type: Article

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