H3 relaxin demonstrates antifibrotic properties via the RXFP1 receptor

Biochemistry

Volumn 50, Issue 8, 2011, Pages 1368-1375

  Hossain, Mohammed Akhter ^a   Chow Suet Man, Bryna ^a   Zhao, Chongxin ^a   Xu, Qi ^b   Du, Xiao Jun ^b   Wade, John D ^a   Samuel, Chrishan S ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFIBROTIC EFFECT; COLLAGEN DEPOSITION; HUMAN GENES; IN-VITRO; IN-VIVO; INHIBITORY EFFECT; LEFT VENTRICULAR; MATRIX METALLOPROTEINASES; METALLOPROTEINASES; MOUSE MODELS; MYOFIBROBLASTS; OVER-EXPRESSION; PEPTIDE RECEPTOR; TISSUE INHIBITOR; TRANSFORMING GROWTH FACTORS; UNTREATED CONTROL;

CELL CULTURE; ENZYME INHIBITION; FIBROBLASTS; PEPTIDES; PHOSPHORYLATION; TISSUE;

COLLAGEN;

COLLAGEN; COLLAGENASE 3; GELATINASE B; HORMONE RECEPTOR; HUMAN GENE 3 RELAXIN; RELAXIN; RELAXIN FAMILY PEPTIDE RECEPTOR 1; SMAD2 PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOMYOPATHY; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; HEART MUSCLE FIBROSIS; MALE; MOUSE; MYOFIBROBLAST; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; COLLAGEN; DRUG SYNERGISM; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEART VENTRICLES; HUMANS; MALE; MATRIX METALLOPROTEINASES; MICE; RATS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PEPTIDE; RELAXIN; TISSUE INHIBITOR OF METALLOPROTEINASES; TRANSFORMING GROWTH FACTOR BETA1;

RATTUS;

EID: 79951939642     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi1013968     Document Type: Article

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