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Volumn 353, Issue 2-3, 2011, Pages 495-500

An efficient diphosphine/hybrid-amine combination for ruthenium(II)- catalyzed asymmetric hydrogenation of aryl ketones

Author keywords

alcohols; asymmetric catalysis; hydrogenation; N ligands; ruthenium

Indexed keywords


EID: 79951834200     PISSN: 16154150     EISSN: 16154169     Source Type: Journal    
DOI: 10.1002/adsc.201000577     Document Type: Article
Times cited : (39)

References (56)
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    • See also
    • See also
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    • DIOP=2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane, see.
    • DIOP=2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane, see:, W. Dumont, J.-C. Poulin, T.-D. Dang, H. B. Kagan, J. Am. Chem. Soc. 1973, 95, 8295-8299.
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    • See Supporting Information for (further) experimental results and/or details
    • See Supporting Information for (further) experimental results and/or details.
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    • Turnover frequency (TOF) is defined as mol of product per mol of catalyst per hour
    • Turnover frequency (TOF) is defined as mol of product per mol of catalyst per hour.
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    • note
    • Similar hydrogenation using other protic solvents (MeOH, EtOH, i-PrOH, n-BuOH) were considerably slower requiring relatively long reaction times (>12ah) under analogous conditions.
  • 53
    • 79951831278 scopus 로고    scopus 로고
    • AH under analogous conditions using a toluene/(S)-1-phenylethanol 9:1 (v/v) mixture as solvent showed reduced activity (80% conv./2ah, 90% ee). The same inhibitory effect by product (S)-2 may lower TOF in toluene solvent at high conversions.
    • AH under analogous conditions using a toluene/(S)-1-phenylethanol 9:1 (v/v) mixture as solvent showed reduced activity (80% conv./2ah, 90% ee). The same inhibitory effect by product (S)-2 may lower TOF in toluene solvent at high conversions.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.