Asymmetric hydrogenation of ketones catalyzed by RuII-bicp complexes

Angewandte Chemie - International Edition

Volumn 43, Issue 21, 2004, Pages 2816-2819

  Genov, Daniel G ^a,b   Ager, David J ^a  

^a DSM Pharmaceutical Products   (Netherlands)

^b THERAVANCE INC   (United States)

Author keywords

Asymmetric hydrogenation; Bicp ligands; Phosphanes; Ruthenium

Indexed keywords

AMINES; CATALYSIS; HYDROGENATION; RUTHENIUM COMPOUNDS;

AMINE LIGANDS; ENANTIOSELECTIVITY;

KETONES;

ALKANE DERIVATIVE; DIAMINE DERIVATIVE; HYDROGEN; KETONE DERIVATIVE; LIGAND; RUTHENIUM DERIVATIVE; SOLVENT; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; KETONE; ORGANOMETALLIC COMPOUND; PHOSPHINE DERIVATIVE; RHENIUM; RUBIDIUM;

ARTICLE; ASYMMETRIC CATALYSIS; CHIRALITY; ENANTIOSELECTIVITY; HYDROGENATION; CATALYSIS; CHEMISTRY; STEREOISOMERISM;

CATALYSIS; HYDROGENATION; INDICATORS AND REAGENTS; KETONES; ORGANOMETALLIC COMPOUNDS; PHOSPHINES; RHENIUM; RUBIDIUM; SOLVENTS; STEREOISOMERISM;

EID: 3242660043     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200353441     Document Type: Article

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36. The Supporting Information includes the procedures for preparing the precatalyst and conducting the asymmetric hydrogenation, and detailed analytical methods for determining the ee values.