Evidence that β3 integrin-induced Rac activation involves the calpain-dependent formation of integrin clusters that are distinct from the focal complexes and focal adhesions that form as Rac and RhoA become active

Journal of Cell Biology

Volumn 151, Issue 3, 2000, Pages 685-695

  Bialkowska, Katarzyna ^a   Kulkarni, Sucheta ^a   Du, Xiaoping ^b   Goll, Darrel E ^c   Saido, Takaomi C ^d   Fox, Joan E B ^a,e  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF ILLINOIS   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^e CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

3 Integrin; Calpain; Cell spreading; Integrin clusters; Rac activation

Indexed keywords

CALPAIN; GUANOSINE TRIPHOSPHATASE; INTEGRIN; RAC PROTEIN; RHO FACTOR; BETA3 INTEGRIN; FIBRINOGEN RECEPTOR; FIBRONECTIN; LEUKOCYTE ANTIGEN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; VINCULIN; VITRONECTIN;

ARTICLE; CELL COMMUNICATION; COMPLEX FORMATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; AMINO ACID SUBSTITUTION; ANIMAL; AORTA; BIOLOGICAL MODEL; CATTLE; CELL ADHESION; CELL CULTURE; CELL SIZE; CELL SURFACE; CHEMISTRY; CYTOLOGY; DOMINANT GENE; DRUG ANTAGONISM; ENZYMOLOGY; FOCAL ADHESION; GENETICS; MACROMOLECULE; METABOLISM; MUTATION; PROTEIN BINDING; PROTEIN PROCESSING; VASCULAR ENDOTHELIUM;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIGENS, CD; AORTA; CALPAIN; CATTLE; CELL ADHESION; CELL SIZE; CELL SURFACE EXTENSIONS; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; FIBRONECTINS; FOCAL ADHESIONS; GENES, DOMINANT; HUMANS; INTEGRIN BETA3; MACROMOLECULAR SUBSTANCES; MODELS, BIOLOGICAL; MUTATION; PLATELET MEMBRANE GLYCOPROTEINS; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RAC GTP-BINDING PROTEINS; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; VINCULIN; VITRONECTIN;

EID: 0034734992     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.151.3.685     Document Type: Article

References (42)

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