PKCδ regulates IL-12p40/p70 production by macrophages and dendritic cells, driving a type 1 healer phenotype in cutaneous leishmaniasis

European Journal of Immunology

Volumn 41, Issue 3, 2011, Pages 706-715

  Guler, Reto ^a   Afshar, Mona ^a   Arendse, Berenice ^a   Parihar, Suraj P ^a   Revaz Breton, Melanie ^a   Leitges, Michael ^b   Schwegmann, Anita ^a   Brombacher, Frank ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Cytokines; DC; Kinases; Leishmania; Macrophages

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12P40; INTERLEUKIN 12P70; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NITRIC OXIDE; PARASITE ANTIGEN; PROTEIN KINASE C DELTA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL KILLING; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; DENDRITIC CELL; DISEASE COURSE; EFFECTOR CELL; FOOT PAD; LEISHMANIA MAJOR; LYMPH NODE; MACROPHAGE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NECROSIS; NONHUMAN; PARASITE LOAD; PHENOTYPE; POPLITEAL ARTERY; PRIORITY JOURNAL; SKIN LEISHMANIASIS; SWELLING; TH1 CELL; ULCER; WILD TYPE;

ANIMALS; ANTIGENS, PROTOZOAN; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; HYPERSENSITIVITY, DELAYED; INTERLEUKIN-12; INTERLEUKIN-12 SUBUNIT P40; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; MACROPHAGES; MICE; MICE, 129 STRAIN; MICE, INBRED BALB C; MICE, KNOCKOUT; PHENOTYPE; PROTEIN KINASE C-DELTA; SPECIES SPECIFICITY; TH1 CELLS;

EID: 79951775594     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201040985     Document Type: Article

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