Crotonaldehyde induces oxidative stress and caspase-dependent apoptosis in human bronchial epithelial cells

Toxicology Letters

Volumn 195, Issue 1, 2010, Pages 90-98

  Liu, Xing yu ^a,b   Yang, Zhi hua ^c   Pan, Xiu jie ^c   Zhu, Mao xiang ^c   Xie, Jian ping ^b  

^a DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

^b ZHENGZHOU TOBACCO RESEARCH INSTITUTE OF CNTC   (China)

^c BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

Author keywords

Apoptosis; Caspase; Crotonaldehyde; Oxidative stress

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE; CASPASE 3; CASPASE 7; CASPASE 9; CROTONALDEHYDE; CYTOCHROME C; FLUORESCEIN ISOTHIOCYANATE; GLUTATHIONE; LIPOCORTIN 5; PROPIDIUM IODIDE; 2-BUTENAL; ALDEHYDE;

APOPTOSIS; ARTICLE; BRONCHUS MUCOSA; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME ANALYSIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SECRETION; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; TOXICITY TESTING; UPREGULATION; BRONCHUS; CELL LINE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; EPITHELIUM CELL; METABOLISM; MITOCHONDRION; PHYSIOLOGY; RESPIRATORY TRACT MUCOSA;

ALDEHYDES; APOPTOSIS; BRONCHI; CASPASES; CELL LINE; CYTOCHROMES C; EPITHELIAL CELLS; GLUTATHIONE; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXIDATIVE STRESS; RESPIRATORY MUCOSA;

EID: 77951924602     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.02.004     Document Type: Article

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