메뉴 건너뛰기




Volumn 10, Issue 3, 2011, Pages 370-390

Pharmacotherapy and prevention of vascular dementia

Author keywords

Alzheimer's disease; Dementia; Prevention; Therapy; Vascular dementia

Indexed keywords

ACETYLSALICYLIC ACID; ATORVASTATIN; CANDESARTAN; DIHYDROERGOTOXINE MESILATE; DONEPEZIL; ENALAPRIL MALEATE PLUS NITRENDIPINE; FENOFIBRATE; GALANTAMINE; GINKGO BILOBA EXTRACT; HYDROCHLOROTHIAZIDE; INDAPAMIDE PLUS PERINDOPRIL; INSULIN; MEMANTINE; NAFTIDROFURYL; NICARDIPINE; NICERGOLINE; NIMODIPINE; NITRENDIPINE; NONSTEROID ANTIINFLAMMATORY AGENT; NOOTROPIC AGENT; PENTOXIFYLLINE; PERINDOPRIL; PIRACETAM; PITAVASTATIN; PLACEBO; PROPENTOFYLLINE; RIVASTIGMINE; ROSIGLITAZONE; SIBUTRAMINE; UNINDEXED DRUG;

EID: 79951718638     PISSN: 18715273     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152711794653832     Document Type: Article
Times cited : (33)

References (293)
  • 1
    • 0025094650 scopus 로고
    • Vascular dementia
    • Loeb, C. Vascular dementia. Dementia, 1990, 1, 175-184.
    • (1990) Dementia , vol.1 , pp. 175-184
    • Loeb, C.1
  • 2
    • 0038076409 scopus 로고    scopus 로고
    • Vascular dementia: Distinguishing characteristics, treatment and prevention
    • Román, G.C. Vascular dementia: distinguishing characteristics, treatment and prevention. J. Am. Geriatr. Soc., 2003, 51, 1-9.
    • (2003) J. Am. Geriatr. Soc , vol.51 , pp. 1-9
    • Román, G.C.1
  • 3
    • 79951710718 scopus 로고    scopus 로고
    • Bowler, J.V.; Hachinski, V., Eds., Oxford University Press: Oxford
    • Bowler, J.V.; Hachinski, V., Eds.; Vascular Cognitive Impairment: Preventable Dementia. Oxford University Press: Oxford, 2003, pp. 1-337.
    • (2003) Vascular Cognitive Impairment: Preventable Dementia , pp. 1-337
  • 4
    • 33846907403 scopus 로고    scopus 로고
    • Vascular dementia: Emerging trends
    • Aggarwal, N.T.; DeCarli, C. Vascular dementia: emerging trends. Semin. Neurol., 2007, 27, 66-77.
    • (2007) Semin. Neurol , vol.27 , pp. 66-77
    • Aggarwal, N.T.1    DeCarli, C.2
  • 5
    • 44649131215 scopus 로고    scopus 로고
    • Morphological diagnosis of vascular dementia-A critical update
    • Jellinger, K.A. Morphological diagnosis of vascular dementia-A critical update. J. Neurol. Sci., 2008, 270, 1-12.
    • (2008) J. Neurol. Sci , vol.270 , pp. 1-12
    • Jellinger, K.A.1
  • 7
    • 1842418653 scopus 로고    scopus 로고
    • Emerging therapies for vascular dementia and vascular cognitive impairment
    • Erkinijuntti, T.; Román, G.; Gauthier, S.; Feldman, H.; Rockwood, K. Emerging therapies for vascular dementia and vascular cognitive impairment. Stroke, 2004, 35, 1010-1017.
    • (2004) Stroke , vol.35 , pp. 1010-1017
    • Erkinijuntti, T.1    Román, G.2    Gauthier, S.3    Feldman, H.4    Rockwood, K.5
  • 8
    • 34447326157 scopus 로고    scopus 로고
    • The relation between whitematter lesions and cognition
    • Pantoni, L.; Poggesi, A.; Inzitari, D. The relation between whitematter lesions and cognition. Curr. Opin. Neurol., 2007, 20, 390-397.
    • (2007) Curr. Opin. Neurol , vol.20 , pp. 390-397
    • Pantoni, L.1    Poggesi, A.2    Inzitari, D.3
  • 9
    • 0036131036 scopus 로고    scopus 로고
    • Subcortical vascular dementia
    • Erkinijuntti, T. Subcortical vascular dementia. Cerebrovasc. Dis., 2002, 13(Suppl. 2), 58-60.
    • (2002) Cerebrovasc. Dis , vol.13 , Issue.2 , pp. 58-60
    • Erkinijuntti, T.1
  • 10
    • 0141596206 scopus 로고    scopus 로고
    • Regulatory aspects of vascular dementia in the United States
    • Oliva, A.; Mani, R.; Katz, R. Regulatory aspects of vascular dementia in the United States. Int. Psychogeriatr., 2003, 15(Suppl 1), 293-295.
    • (2003) Int. Psychogeriatr , vol.15 , Issue.1 , pp. 293-295
    • Oliva, A.1    Mani, R.2    Katz, R.3
  • 11
    • 5444222589 scopus 로고    scopus 로고
    • Diagnosis, risk factors, and treatment of vascular dementia
    • Lopez, O.L.; Kuller, L.H.; Becker, J.T. Diagnosis, risk factors, and treatment of vascular dementia. Curr. Neurol. Neurosci. Rep., 2004, 4, 358-367.
    • (2004) Curr. Neurol. Neurosci. Rep , vol.4 , pp. 358-367
    • Lopez, O.L.1    Kuller, L.H.2    Becker, J.T.3
  • 13
    • 79951687970 scopus 로고    scopus 로고
    • Cerebral Blood Flow and Metabolism in Vascular Dementia
    • Preventable Dementia, Bowler, J.V.; Hachinski, V, Eds.; Oxford University Press: Oxford
    • Ward, N.S.; Brown M.M. In: Cerebral Blood Flow and Metabolism in Vascular Dementia. Vascular Cognitive Impairment. Preventable Dementia, Bowler, J.V.; Hachinski, V, Eds.; Oxford University Press: Oxford, 2003; pp. 193-207.
    • (2003) Vascular Cognitive Impairment , pp. 193-207
    • Ward, N.S.1    Brown, M.M.2
  • 17
    • 26644456114 scopus 로고    scopus 로고
    • Neuropsychological Differentiation of Alzheimer's Disease and Vascular Dementia
    • Preventable Dementia, Bowler, J.V.; Hachinski, V, Eds.; Oxford University Press: Oxford
    • Sachdef, P.F.; Looi, J.C. In: Neuropsychological Differentiation of Alzheimer's Disease and Vascular Dementia. Vascular Cognitive Impairment. Preventable Dementia, Bowler, J.V.; Hachinski, V, Eds.; Oxford University Press: Oxford, 2003; pp. 153-175.
    • (2003) Vascular Cognitive Impairment , pp. 153-175
    • Sachdef, P.F.1    Looi, J.C.2
  • 18
    • 33746291203 scopus 로고    scopus 로고
    • 18FDG PET in vascular dementia: Differentiation from Alzheimer's disease using voxel-based multivariare analysis
    • Kerrouche, N.; Herholz, K.; Mielke, R.; Holthoff, V.; Baron, J.-C. 18FDG PET in vascular dementia: differentiation from Alzheimer's disease using voxel-based multivariare analysis. J Cerebr. Flow Metab., 2006, 26, 1213-1221.
    • (2006) J Cerebr. Flow Metab , vol.26 , pp. 1213-1221
    • Kerrouche, N.1    Herholz, K.2    Mielke, R.3    Holthoff, V.4    Baron, J.-C.5
  • 19
    • 34548477702 scopus 로고    scopus 로고
    • Cognitive deficits in preclinical Alzheimer's disease and vascular dementia: Patterns of findings from the Kungsholmen Project
    • Bäckman, L.; Small, B.J. Cognitive deficits in preclinical Alzheimer's disease and vascular dementia: patterns of findings from the Kungsholmen Project. Physiol. Behav., 2007, 92, 80-86.
    • (2007) Physiol. Behav , vol.92 , pp. 80-86
    • Bäckman, L.1    Small, B.J.2
  • 20
    • 1642525877 scopus 로고    scopus 로고
    • Aβ-related cerebral amyloid angiopathy
    • Bugiani, O. Aβ-related cerebral amyloid angiopathy. Neurol. Sci., 2004, 25, S1-S2.
    • (2004) Neurol. Sci , vol.25
    • Bugiani, O.1
  • 21
    • 33750022878 scopus 로고    scopus 로고
    • Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia
    • Román, G.C.; Kalaria, R.N. Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia. Neurobiol. Aging, 2006, 27, 1769-1785.
    • (2006) Neurobiol. Aging , vol.27 , pp. 1769-1785
    • Román, G.C.1    Kalaria, R.N.2
  • 22
    • 0029842588 scopus 로고    scopus 로고
    • Cerebrospinal fluid acetylcholine and choline in vascular dementia of Binswanger and multiple small infarct types as compared with Alzheimer-type dementia
    • Tohgi, H.; Abe, T.; Kimura, M.; Saheki, M.; Takahashi, S. Cerebrospinal fluid acetylcholine and choline in vascular dementia of Binswanger and multiple small infarct types as compared with Alzheimer-type dementia. J. Neural Transm., 1996, 103, 1211-1220.
    • (1996) J. Neural Transm , vol.103 , pp. 1211-1220
    • Tohgi, H.1    Abe, T.2    Kimura, M.3    Saheki, M.4    Takahashi, S.5
  • 23
    • 0141706644 scopus 로고    scopus 로고
    • Decreased cerebrovascular fluid acetylcholinesterase in patients with subcortical ischemic vascular dementia
    • Wallin, A.; Sjögren, M.; Blennow, K.; Davidsson, P. Decreased cerebrovascular fluid acetylcholinesterase in patients with subcortical ischemic vascular dementia. Dement. Geriatr. Cogn. Disord., 2003, 16, 200-207.
    • (2003) Dement. Geriatr. Cogn. Disord , vol.16 , pp. 200-207
    • Wallin, A.1    Sjögren, M.2    Blennow, K.3    Davidsson, P.4
  • 25
    • 0025368758 scopus 로고
    • Substance P-like immunoreactivity, choline acetyltransferase activity and cholinergic muscarinic receptors in Azheimer' disease and multiinfarct dementia
    • Sakurada, T.; Alufuzoff, I.; Winblad, B.; Nordberg, A. Substance P-like immunoreactivity, choline acetyltransferase activity and cholinergic muscarinic receptors in Azheimer' disease and multiinfarct dementia. Brain Res., 1990, 521, 329-332.
    • (1990) Brain Res , vol.521 , pp. 329-332
    • Sakurada, T.1    Alufuzoff, I.2    Winblad, B.3    Nordberg, A.4
  • 26
    • 11444268288 scopus 로고    scopus 로고
    • Absence of cholinergic deficits in "pure" vascular dementia
    • Perry, E.; Ziabreva, I.; Perry, R.; Aarsland, D.; Ballard, C. Absence of cholinergic deficits in "pure" vascular dementia. Neurology, 2005, 64, 132-133.
    • (2005) Neurology , vol.64 , pp. 132-133
    • Perry, E.1    Ziabreva, I.2    Perry, R.3    Aarsland, D.4    Ballard, C.5
  • 29
  • 31
    • 0034125843 scopus 로고    scopus 로고
    • On neurodegenerative diseases, models and treatment strategies: Lessons learned and lessons forgotten a generation following the cholinergic hypothesis
    • Bartus, R.T. On neurodegenerative diseases, models and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis. Exp. Neurol., 2000, 163, 495-529.
    • (2000) Exp. Neurol , vol.163 , pp. 495-529
    • Bartus, R.T.1
  • 32
    • 0034816672 scopus 로고    scopus 로고
    • Treatment of cognitive dysfunction associated with Alzheimer's disease with cholinergic precursors: Ineffective treatments or inappropriate approaches?
    • Amenta, F.; Parnetti, L.; Gallai, V.; Wallin, A. Treatment of cognitive dysfunction associated with Alzheimer's disease with cholinergic precursors: ineffective treatments or inappropriate approaches? Mech. Ageing Dev., 2001, 122, 2025-2040.
    • (2001) Mech. Ageing Dev , vol.122 , pp. 2025-2040
    • Amenta, F.1    Parnetti, L.2    Gallai, V.3    Wallin, A.4
  • 33
    • 0036814122 scopus 로고    scopus 로고
    • The cholinergic approach for the treatment of vascular dementia: Evidence from pre-clinical and clinical studies
    • Amenta, F.; Di Tullio, M.A.; Tomassoni, D. The cholinergic approach for the treatment of vascular dementia: evidence from pre-clinical and clinical studies. Clin. Exp. Hypertens., 2002, 24, 697-713.
    • (2002) Clin. Exp. Hypertens , vol.24 , pp. 697-713
    • Amenta, F.1    Di Tullio, M.A.2    Tomassoni, D.3
  • 34
    • 34249803604 scopus 로고    scopus 로고
    • Cholinergic precursors in the treatment of cognitive impairment of vascular origin: Ineffective approaches or need for re-evaluation
    • Parnetti, L.; Mignini, F.; Tomassoni, D.; Traini, E.; Amenta, F. Cholinergic precursors in the treatment of cognitive impairment of vascular origin: ineffective approaches or need for re-evaluation? J. Neurol. Sci., 2007, 257, 264-269.
    • (2007) J. Neurol. Sci , vol.257 , pp. 264-269
    • Parnetti, L.1    Mignini, F.2    Tomassoni, D.3    Traini, E.4    Amenta, F.5
  • 35
    • 21844442389 scopus 로고    scopus 로고
    • Cytidinediphosphocholine (CDPcholine) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly
    • Fioravanti, M.; Yanagi, M. Cytidinediphosphocholine (CDPcholine) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database Syst. Rev., 2005, 2, CD000269.
    • (2005) Cochrane Database Syst. Rev , vol.2
    • Fioravanti, M.1    Yanagi, M.2
  • 36
    • 33749263352 scopus 로고    scopus 로고
    • Use of antidementia agents in vascular dementia: Beyond Alzheimer disease
    • Farlow, M.R. Use of antidementia agents in vascular dementia: beyond Alzheimer disease. Mayo Clin. Proc., 2006, 81, 1350-1358.
    • (2006) Mayo Clin. Proc , vol.81 , pp. 1350-1358
    • Farlow, M.R.1
  • 37
    • 0242523117 scopus 로고    scopus 로고
    • The effect of cholinesterase inhibitors on the regional blood flow in patients with Alzheimer's disease and vascular dementia
    • Lojkowska, W.; Ryglewicz, D.; Jedrzejczak, T.; Minc, S.; Jakubowska, T.; Jarosz, H.; Bochynska, A. The effect of cholinesterase inhibitors on the regional blood flow in patients with Alzheimer's disease and vascular dementia. J. Neurol. Sci., 2003, 216, 119-126.
    • (2003) J. Neurol. Sci , vol.216 , pp. 119-126
    • Lojkowska, W.1    Ryglewicz, D.2    Jedrzejczak, T.3    Minc, S.4    Jakubowska, T.5    Jarosz, H.6    Bochynska, A.7
  • 40
    • 0037070773 scopus 로고    scopus 로고
    • Efficacy of galantamine in probable vascular dementia and Alzheimer's disease combined with cerebrovascular disease: A randomised trial
    • Erkinjuntti, T.; Kurz, A.; Gauthier, S.; Bullock, R.; Lilienfeld, S.; Damaraju, C.V. Efficacy of galantamine in probable vascular dementia and Alzheimer's disease combined with cerebrovascular disease: a randomised trial. Lancet, 2002, 359, 1283-1290.
    • (2002) Lancet , vol.359 , pp. 1283-1290
    • Erkinjuntti, T.1    Kurz, A.2    Gauthier, S.3    Bullock, R.4    Lilienfeld, S.5    Damaraju, C.V.6
  • 43
    • 34547787131 scopus 로고    scopus 로고
    • Efficacy and adverse effects of cholinesterase inhibitors and memantine in vascular dementia: A meta-analysis of randomised controlled trials
    • Kavirajan, H.; Schneider, L.S. Efficacy and adverse effects of cholinesterase inhibitors and memantine in vascular dementia: a meta-analysis of randomised controlled trials. Lancet Neurol., 2007, 6, 782-792.
    • (2007) Lancet Neurol , vol.6 , pp. 782-792
    • Kavirajan, H.1    Schneider, L.S.2
  • 45
    • 0033844518 scopus 로고    scopus 로고
    • Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex
    • Kuhl, D.E.; Minoshima, S.; Frey, K.A.; Foster, N.L.; Kilbourn, M.R.; Koeppe, R.A. Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex. Ann. Neurol., 2000, 48, 391-395.
    • (2000) Ann. Neurol , vol.48 , pp. 391-395
    • Kuhl, D.E.1    Minoshima, S.2    Frey, K.A.3    Foster, N.L.4    Kilbourn, M.R.5    Koeppe, R.A.6
  • 46
    • 0037195557 scopus 로고    scopus 로고
    • Effects of huperzine A on acetylcholinesterase isoforms in vitro: Comparison with tacrine, donepezil, rivastigmine and physostigmine
    • Zhao, Q.; Tang, X.C. Effects of huperzine A on acetylcholinesterase isoforms in vitro: comparison with tacrine, donepezil, rivastigmine and physostigmine. Eur. J. Pharmacol., 2002, 455, 101-107.
    • (2002) Eur. J. Pharmacol , vol.455 , pp. 101-107
    • Zhao, Q.1    Tang, X.C.2
  • 47
    • 30844446707 scopus 로고    scopus 로고
    • Circadian cholinergic rhythms: Implications for cholinesterase inhibitor therapy
    • Davis, B.; Sadik, K. Circadian cholinergic rhythms: implications for cholinesterase inhibitor therapy. Dement. Geriatr. Cogn. Disord., 2006, 21, 120-129.
    • (2006) Dement. Geriatr. Cogn. Disord , vol.21 , pp. 120-129
    • Davis, B.1    Sadik, K.2
  • 48
    • 64549160661 scopus 로고    scopus 로고
    • Cholinesterase inhibitors and beyond
    • Pepeu, G.; Giovannini, M.G. Cholinesterase inhibitors and beyond. Curr. Alzheimer Res., 2009, 6, 86-96.
    • (2009) Curr. Alzheimer Res , vol.6 , pp. 86-96
    • Pepeu, G.1    Giovannini, M.G.2
  • 49
    • 33646244725 scopus 로고    scopus 로고
    • Cholinesterase inhibitors: Drugs looking for a disease?
    • Maggini, M.; Vanacore, N.; Raschetti, R. Cholinesterase inhibitors: drugs looking for a disease? PLoS Med., 2006, 3, 40.
    • (2006) PLoS Med , vol.3 , pp. 40
    • Maggini, M.1    Vanacore, N.2    Raschetti, R.3
  • 50
    • 34547796419 scopus 로고    scopus 로고
    • Drugs for vascular dementia
    • Korczyn, A.D. Drugs for vascular dementia. Lancet Neurol., 2007, 6, 749-751.
    • (2007) Lancet Neurol , vol.6 , pp. 749-751
    • Korczyn, A.D.1
  • 52
    • 0028694915 scopus 로고
    • Agerelated alterations by chronic intermittent hypoxia on cerebral synaptosomal ATPase activities
    • Benzi, G.; Gorini, A.; Arnaboldi, R.; Ghigini, B.; Villa, R.F. Agerelated alterations by chronic intermittent hypoxia on cerebral synaptosomal ATPase activities. J. Neural Transm., 1994, 44, 159-171.
    • (1994) J. Neural Transm , vol.44 , pp. 159-171
    • Benzi, G.1    Gorini, A.2    Arnaboldi, R.3    Ghigini, B.4    Villa, R.F.5
  • 53
    • 0036744937 scopus 로고    scopus 로고
    • ATP-ases of synaptic plasma membranes from hippocampus after ischemia and recovery during ageing
    • Villa, R.F.; Gorini, A.; Hoyer, S. ATP-ases of synaptic plasma membranes from hippocampus after ischemia and recovery during ageing. Neurochem. Res., 2002, 27, 861-870.
    • (2002) Neurochem. Res , vol.27 , pp. 861-870
    • Villa, R.F.1    Gorini, A.2    Hoyer, S.3
  • 54
    • 70450227567 scopus 로고    scopus 로고
    • Effect of ageing and ischemia on enzymatic actitivites linked to Krebs' cycle, electron transfer chain, glutamate and aminoacids metabolism of free and intrasynaptic mithocondria of cerebral cortex
    • Villa, R.F.; Gorini, A.; Hoyer, S.; Effect of ageing and ischemia on enzymatic actitivites linked to Krebs' cycle, electron transfer chain, glutamate and aminoacids metabolism of free and intrasynaptic mithocondria of cerebral cortex. Neurochem. Res., 2009, 34, 2102-2116.
    • (2009) Neurochem. Res , vol.34 , pp. 2102-2116
    • Villa, R.F.1    Gorini, A.2    Hoyer, S.3
  • 57
    • 1642422286 scopus 로고    scopus 로고
    • Inhibition of human a7 nicotinic acetylcholine receptors by open channel blockers of N-methyl-D-aspartate receptors
    • Maskell, P.D.; Speder, P.; Newberry, N.R.; Bermudez, I. Inhibition of human a7 nicotinic acetylcholine receptors by open channel blockers of N-methyl-D-aspartate receptors. Br. J. Pharmacol., 2003, 140, 1313-1319.
    • (2003) Br. J. Pharmacol , vol.140 , pp. 1313-1319
    • Maskell, P.D.1    Speder, P.2    Newberry, N.R.3    Bermudez, I.4
  • 58
    • 0036314492 scopus 로고    scopus 로고
    • Efficacy and safety of memantine in patients with mild to moderate vascular dementia: A randomized, placebo-controlled trial (MMM 300)
    • Orgogozo, J.M.; Rigaud, A.S.; Stöffler, A.; Möbius, H.J.; Forette, F. Efficacy and safety of memantine in patients with mild to moderate vascular dementia: a randomized, placebo-controlled trial (MMM 300). Stroke, 2002, 33, 1834-1839.
    • (2002) Stroke , vol.33 , pp. 1834-1839
    • Orgogozo, J.M.1    Rigaud, A.S.2    Stöffler, A.3    Möbius, H.J.4    Forette, F.5
  • 59
    • 0036840767 scopus 로고    scopus 로고
    • A double-blind, placebocontrolled multicentre study of memantine in mild to moderate vascular dementia (MMM 500)
    • Wilcock, G.; Möbius, H.J.; Stöffler, A. A double-blind, placebocontrolled multicentre study of memantine in mild to moderate vascular dementia (MMM 500). Int. Clin. Psychopharmacol., 2002, 17, 297-305.
    • (2002) Int. Clin. Psychopharmacol , vol.17 , pp. 297-305
    • Wilcock, G.1    Möbius, H.J.2    Stöffler, A.3
  • 61
    • 0025672862 scopus 로고
    • Effects of co-dergocrine mesylate (Hydergine) in multi-infarct dementia as evaluated by positron emission tomography
    • Nagasawa, H.; Kogure, K.; Kawashima, K.; Ido, T.; Itoh, M.; Hatazawa, J. Effects of co-dergocrine mesylate (Hydergine) in multi-infarct dementia as evaluated by positron emission tomography. Tohoku J. Exp. Med., 1990, 162, 225-233.
    • (1990) Tohoku J. Exp. Med , vol.162 , pp. 225-233
    • Nagasawa, H.1    Kogure, K.2    Kawashima, K.3    Ido, T.4    Itoh, M.5    Hatazawa, J.6
  • 62
    • 0028141762 scopus 로고
    • Overview of clinical trials of Hydergine in dementia
    • Schneider, L.S.; Olin, J.T. Overview of clinical trials of Hydergine in dementia. Arch. Neurol., 1994, 51, 787-798.
    • (1994) Arch. Neurol , vol.51 , pp. 787-798
    • Schneider, L.S.1    Olin, J.T.2
  • 64
    • 0016741806 scopus 로고
    • Effect of hypoxia on the cerebral energy state
    • Villa, R.F. Effect of hypoxia on the cerebral energy state. Il Farmaco Ed. Sci., 1975, 30, 561-567.
    • (1975) Il Farmaco Ed. Sci , vol.30 , pp. 561-567
    • Villa, R.F.1
  • 65
    • 0018705664 scopus 로고
    • Metabolic and neurochemical effects of nicergoline on the central nervous system: A review of the experimental studies (in German)
    • Moretti, A. Metabolic and neurochemical effects of nicergoline on the central nervous system: a review of the experimental studies (in German). Arzneim.-Forsch. Drug Res., 1979, 29, 1213-1223.
    • (1979) Arzneim.-Forsch. Drug Res , vol.29 , pp. 1213-1223
    • Moretti, A.1
  • 66
    • 0021356987 scopus 로고
    • Simultaneous study of haemodynamic, metabolic and behavioural sequelae in a model of cerebral ischaemia in aged rats: Effects of nicergoline
    • Le Poncin-Lafitte, M.; Grosdemouge, C.; Duterte, D.; Rapin, J.R. Simultaneous study of haemodynamic, metabolic and behavioural sequelae in a model of cerebral ischaemia in aged rats: effects of nicergoline. Gerontology, 1984, 30, 109-119.
    • (1984) Gerontology , vol.30 , pp. 109-119
    • Le Poncin-Lafitte, M.1    Grosdemouge, C.2    Duterte, D.3    Rapin, J.R.4
  • 69
    • 0016730962 scopus 로고
    • Inhibition of human platelet aggregation by oral administration of nicergoline: A double-blind study
    • Pogliani, E.; della Volpe, A.; Ferrari, R.; Recalcati, P.; Praga, C. Inhibition of human platelet aggregation by oral administration of nicergoline: a double-blind study. Farmaco Prat., 1975, 30, 630-640.
    • (1975) Farmaco Prat , vol.30 , pp. 630-640
    • Pogliani, E.1    della Volpe, A.2    Ferrari, R.3    Recalcati, P.4    Praga, C.5
  • 70
    • 0028935334 scopus 로고
    • Nicergoline in senile dementia of Alzheimer type and multi-infarct dementia: A double-blind, placebo-controlled, clinical and EEG/ERP mapping study
    • Saletu, B.; Paulus, E.; Linzmayer, L.; Anderer, P.; Semlitsch, H.V.; Grünberger, J.; Wicke, L.; Neuhold, A.; Podreka, I. Nicergoline in senile dementia of Alzheimer type and multi-infarct dementia: a double-blind, placebo-controlled, clinical and EEG/ERP mapping study. Psychopharmacology, 1995, 117, 385-395.
    • (1995) Psychopharmacology , vol.117 , pp. 385-395
    • Saletu, B.1    Paulus, E.2    Linzmayer, L.3    Anderer, P.4    Semlitsch, H.V.5    Grünberger, J.6    Wicke, L.7    Neuhold, A.8    Podreka, I.9
  • 71
    • 0030956210 scopus 로고    scopus 로고
    • A multicenter randomized double-blind study on the efficacy and safety of nicergoline in patients with multi-infarct dementia
    • Herrmann, W.H.; Stephan, K.; Gaede, K.; Apeceche, M. A multicenter randomized double-blind study on the efficacy and safety of nicergoline in patients with multi-infarct dementia. Dement. Geriatr. Cogn. Disord., 1997, 8, 9-17.
    • (1997) Dement. Geriatr. Cogn. Disord , vol.8 , pp. 9-17
    • Herrmann, W.H.1    Stephan, K.2    Gaede, K.3    Apeceche, M.4
  • 72
    • 0035231829 scopus 로고    scopus 로고
    • Effect of nicergoline in dementia and other age associated forms of cognitive impairment
    • Fioravanti, M.; Flicker, L. Effect of nicergoline in dementia and other age associated forms of cognitive impairment. Cochrane Database Syst. Rev., 2001, 4, CD003159.
    • (2001) Cochrane Database Syst. Rev , vol.4
    • Fioravanti, M.1    Flicker, L.2
  • 74
    • 0031059592 scopus 로고    scopus 로고
    • Effects of nimodipine on learning in normotensive and spontaneously hypertensive rats
    • Meneses, A.; Terrón, J.A.; Ibarra, M.; Hong, E. Effects of nimodipine on learning in normotensive and spontaneously hypertensive rats. Behav. Brain Res., 1997, 85, 121-125.
    • (1997) Behav. Brain Res , vol.85 , pp. 121-125
    • Meneses, A.1    Terrón, J.A.2    Ibarra, M.3    Hong, E.4
  • 76
    • 56549130363 scopus 로고    scopus 로고
    • Nimodipine and its use in cerebrovascular disease: Evidence from recent preclinical and controlled clinical studies
    • Tomassoni, D.; Lanari, A.; Silvestrelli, G.; Traini, E.; Amenta, F. Nimodipine and its use in cerebrovascular disease: evidence from recent preclinical and controlled clinical studies. Clin. Exp. Hypertens., 2008, 30, 744-766.
    • (2008) Clin. Exp. Hypertens , vol.30 , pp. 744-766
    • Tomassoni, D.1    Lanari, A.2    Silvestrelli, G.3    Traini, E.4    Amenta, F.5
  • 77
    • 0036046464 scopus 로고    scopus 로고
    • Nimodipine for primary degenerative, mixed and vascular dementia
    • Lopez-Arrieta, J.M.; Birks, J. Nimodipine for primary degenerative, mixed and vascular dementia. Cochrane Database Syst. Rev., 2002, 1, CD000147.
    • (2002) Cochrane Database Syst. Rev , vol.1
    • Lopez-Arrieta, J.M.1    Birks, J.2
  • 78
    • 14844323654 scopus 로고    scopus 로고
    • Efficacy and safety of nimodipine in subcortical vascular dementia: A randomized placebo-controlled trial
    • Pantoni, L.; del Ser, T.; Soglian, A.G.; Amigoni, S.; Spadari, G.; Binelli, D.; Inzitari, D. Efficacy and safety of nimodipine in subcortical vascular dementia: a randomized placebo-controlled trial. Stroke, 2005, 36, 619-624.
    • (2005) Stroke , vol.36 , pp. 619-624
    • Pantoni, L.1    del Ser, T.2    Soglian, A.G.3    Amigoni, S.4    Spadari, G.5    Binelli, D.6    Inzitari, D.7
  • 79
    • 56549108336 scopus 로고    scopus 로고
    • Nicardipine: A hypotensive dihydropyridine-type calcium antagonist with a peculiar cerebrovascular profile
    • Amenta, F.; Tomassoni, D.; Traini, E.; Mignini, F.; Veglio, F. Nicardipine: a hypotensive dihydropyridine-type calcium antagonist with a peculiar cerebrovascular profile. Clin. Exp. Hypertens., 2008, 30, 808-826.
    • (2008) Clin. Exp. Hypertens , vol.30 , pp. 808-826
    • Amenta, F.1    Tomassoni, D.2    Traini, E.3    Mignini, F.4    Veglio, F.5
  • 80
    • 0033064874 scopus 로고    scopus 로고
    • An experimental, randomized, double-blind, placebo-controlled clinical trial to investigate the effect of nicardipine on cognitive function in patients with vascular dementia (in Spanish)
    • Spanish Group of Nicardipine Study in Vascular Dementia
    • Spanish Group of Nicardipine Study in Vascular Dementia. An experimental, randomized, double-blind, placebo-controlled clinical trial to investigate the effect of nicardipine on cognitive function in patients with vascular dementia (in Spanish). Rev. Neurol., 1999, 28, 835-845.
    • (1999) Rev. Neurol , vol.28 , pp. 835-845
  • 81
    • 0034673851 scopus 로고    scopus 로고
    • A study of the tolerability and effectiveness of nicardipine retard in cognitive deterioration of vascular origin (in Spanish)
    • González-González, J.A.; Lozano, R. A study of the tolerability and effectiveness of nicardipine retard in cognitive deterioration of vascular origin (in Spanish). Rev. Neurol., 2000, 30, 719-728.
    • (2000) Rev. Neurol , vol.30 , pp. 719-728
    • González-González, J.A.1    Lozano, R.2
  • 82
    • 0022001454 scopus 로고
    • Comparative randomized study of cerebral blood flow after long-term administration of pentoxifylline and codergocrine mesylate in patients with chronic cerebrovascular disease
    • Hartmann, A. Comparative randomized study of cerebral blood flow after long-term administration of pentoxifylline and codergocrine mesylate in patients with chronic cerebrovascular disease. Curr. Med. Res. Opin., 1985, 9, 475-479.
    • (1985) Curr. Med. Res. Opin , vol.9 , pp. 475-479
    • Hartmann, A.1
  • 83
    • 0019424757 scopus 로고
    • Haemorheology and cerebrovascular disease: Multifunctional approach with pentoxifylline
    • Müller, R.; Lehrach, F. Haemorheology and cerebrovascular disease: multifunctional approach with pentoxifylline. Curr. Med. Res. Opin., 1981, 7, 253-263.
    • (1981) Curr. Med. Res. Opin , vol.7 , pp. 253-263
    • Müller, R.1    Lehrach, F.2
  • 84
    • 0037219722 scopus 로고    scopus 로고
    • The efficacy of pentoxifylline in the treatment of vascular dementia: A systematic review
    • Sha, M.C.; Callahan, C.M. The efficacy of pentoxifylline in the treatment of vascular dementia: a systematic review. Alzheimer Dis. Assoc. Disord., 2003, 17, 46-54.
    • (2003) Alzheimer Dis. Assoc. Disord , vol.17 , pp. 46-54
    • Sha, M.C.1    Callahan, C.M.2
  • 85
    • 0028143648 scopus 로고
    • Propentofylline: A nucleoside transport inhibitor with neuroprotective effects in cerebral ischemia
    • Parkinson, F.E.; Rudolphi, K.A.; Fredholm, B.B. Propentofylline: a nucleoside transport inhibitor with neuroprotective effects in cerebral ischemia. Gen. Pharmacol., 1994, 25, 1053-1058.
    • (1994) Gen. Pharmacol , vol.25 , pp. 1053-1058
    • Parkinson, F.E.1    Rudolphi, K.A.2    Fredholm, B.B.3
  • 86
    • 0024381030 scopus 로고
    • Effects of propentofylline on energy metabolism of the ischemic brain studied by in vivo 31P nuclear magnetic resonance spectroscopy
    • Sasaki, M.; Naritomi, H.; Kanashiro, M.; Nishimura, H.; Sawada, T. Effects of propentofylline on energy metabolism of the ischemic brain studied by in vivo 31P nuclear magnetic resonance spectroscopy. Arzneim. Forsch. Drug Res., 1989, 39, 886-889.
    • (1989) Arzneim. Forsch. Drug Res , vol.39 , pp. 886-889
    • Sasaki, M.1    Naritomi, H.2    Kanashiro, M.3    Nishimura, H.4    Sawada, T.5
  • 87
    • 0031793151 scopus 로고    scopus 로고
    • Effect of propentofylline on hippocampal brain energy state and amyloid precursor protein concentration in a rat model of cerebral hypoperfusion
    • Plaschke, K.; Martin, E.; Bardenheuer, H.J. Effect of propentofylline on hippocampal brain energy state and amyloid precursor protein concentration in a rat model of cerebral hypoperfusion. J. Neural. Transm., 1998, 105, 1065-1077.
    • (1998) J. Neural. Transm , vol.105 , pp. 1065-1077
    • Plaschke, K.1    Martin, E.2    Bardenheuer, H.J.3
  • 88
    • 0023521939 scopus 로고
    • Effects of propentofylline on disorder of learning and memory in rodents
    • Goto, M.; Demura, N.; Sakaguchi, T. Effects of propentofylline on disorder of learning and memory in rodents. Jpn. J. Pharmacol., 1987, 45, 373-378.
    • (1987) Jpn. J. Pharmacol , vol.45 , pp. 373-378
    • Goto, M.1    Demura, N.2    Sakaguchi, T.3
  • 90
    • 0033202339 scopus 로고    scopus 로고
    • Clinical trials of propentofylline in vascular dementia
    • Kittner, B. Clinical trials of propentofylline in vascular dementia. Alzheimer Dis. Assoc. Dis., 1999, 13(Suppl. 3), S166-S171.
    • (1999) Alzheimer Dis. Assoc. Dis , vol.13 , Issue.3
    • Kittner, B.1
  • 92
    • 0022473011 scopus 로고
    • Biochemical and physiological evidence for antiserotoninergic properties of naftidrofuryl
    • Maloteaux, J.M.; Halech, J.; De Campeneere, D.; Berta, P.; Vidal, N. Biochemical and physiological evidence for antiserotoninergic properties of naftidrofuryl. Arzneim. Forsch. Drug Res., 1986, 36, 1194-1198.
    • (1986) Arzneim. Forsch. Drug Res , vol.36 , pp. 1194-1198
    • Maloteaux, J.M.1    Halech, J.2    de Campeneere, D.3    Berta, P.4    Vidal, N.5
  • 95
    • 0027078172 scopus 로고
    • Postischemic breakdown in hippocampal protein synthesis and mnesic deficits in rats: Pharmacological improvement by curative naftidrofuryl treatment
    • Lamproglou, Y.; Le Poncin, M.; Jacques, W.; Wiernsperger, N.; Rapin, J.R. Postischemic breakdown in hippocampal protein synthesis and mnesic deficits in rats: pharmacological improvement by curative naftidrofuryl treatment. Metab. Brain Dis., 1992, 7, 165-174.
    • (1992) Metab. Brain Dis , vol.7 , pp. 165-174
    • Lamproglou, Y.1    Le Poncin, M.2    Jacques, W.3    Wiernsperger, N.4    Rapin, J.R.5
  • 96
    • 0033895841 scopus 로고    scopus 로고
    • Efficacy of naftidrofuryl in patients with vascular or mixed dementia: Results of a multicenter, double-blind trial
    • Emeriau, J.P.; Lehert, P.; Mosnier, M. Efficacy of naftidrofuryl in patients with vascular or mixed dementia: results of a multicenter, double-blind trial. Clin. Ther., 2000, 22, 834-844.
    • (2000) Clin. Ther , vol.22 , pp. 834-844
    • Emeriau, J.P.1    Lehert, P.2    Mosnier, M.3
  • 97
    • 0033460182 scopus 로고    scopus 로고
    • Damaged neuronal energy metabolism and behavior are improved by Ginkgo biloba extract (EGb 761)
    • Hoyer, S.; Lannert, H.; Nöldner, M.; Chatterjee, S.S. Damaged neuronal energy metabolism and behavior are improved by Ginkgo biloba extract (EGb 761). J. Neural Transm., 1999, 106, 1171-1188.
    • (1999) J. Neural Transm , vol.106 , pp. 1171-1188
    • Hoyer, S.1    Lannert, H.2    Nöldner, M.3    Chatterjee, S.S.4
  • 99
    • 0033785945 scopus 로고    scopus 로고
    • The efficacy of ginkgo for elderly people with dementia and age-associated memory impairment: New results of a randomized clinical trial
    • Van Dongen, MC.; van Rossum, E.; Kessels, AG.; Sielhorst, HJ.; Knipschild, PG. The efficacy of ginkgo for elderly people with dementia and age-associated memory impairment: new results of a randomized clinical trial. J. Am. Geriatr. Soc., 2000, 48, 1183-1194.
    • (2000) J. Am. Geriatr. Soc , vol.48 , pp. 1183-1194
    • van Dongen, M.C.1    van Rossum, E.2    Kessels, A.G.3    Sielhorst, H.J.4    Knipschild, P.G.5
  • 100
    • 0034125340 scopus 로고    scopus 로고
    • A 26-week analysis of a doubleblind, placebo-controlled trial of the ginkgo biloba extract EGb 761 in dementia
    • Le Bars, PL.; Kieser, M.; Itil, K.Z. A 26-week analysis of a doubleblind, placebo-controlled trial of the ginkgo biloba extract EGb 761 in dementia. Dement. Geriatr. Cogn. Disord., 2000, 11, 230-237.
    • (2000) Dement. Geriatr. Cogn. Disord , vol.11 , pp. 230-237
    • Le Bars, P.L.1    Kieser, M.2    Itil, K.Z.3
  • 101
    • 67650565600 scopus 로고    scopus 로고
    • Efficacy and tolerability of Ginkgo biloba exctract EGb 761 by type of dementia: Analyses of a randomised controlled trial
    • Napryeyenko, O.; Sonnik, G.; Tartakovsky, I. Efficacy and tolerability of Ginkgo biloba exctract EGb 761 by type of dementia: analyses of a randomised controlled trial. J. Neurol. Sci., 2009, 283, 224-229.
    • (2009) J. Neurol. Sci , vol.283 , pp. 224-229
    • Napryeyenko, O.1    Sonnik, G.2    Tartakovsky, I.3
  • 103
    • 24644479070 scopus 로고    scopus 로고
    • Piracetam: A review of pharmacological properties and clinical uses
    • Winblad, B. Piracetam: a review of pharmacological properties and clinical uses. CNS Drug Rev., 2005, 11, 169-182.
    • (2005) CNS Drug Rev , vol.11 , pp. 169-182
    • Winblad, B.1
  • 104
    • 0023800503 scopus 로고
    • Piracetam elevates muscarinic cholinergic receptor density in the frontal cortex of aged but not of young mice
    • Pilch, H.; Müller, WE. Piracetam elevates muscarinic cholinergic receptor density in the frontal cortex of aged but not of young mice. Psychopharmacology, 1988, 94, 74-78.
    • (1988) Psychopharmacology , vol.94 , pp. 74-78
    • Pilch, H.1    Müller, W.E.2
  • 105
    • 0027179282 scopus 로고
    • Effects of piracetam on N-methyl-Daspartate receptor properties in the aged mouse brain
    • Cohen, SA.; Müller, W.E. Effects of piracetam on N-methyl-Daspartate receptor properties in the aged mouse brain. Pharmacology, 1993, 47, 217-222.
    • (1993) Pharmacology , vol.47 , pp. 217-222
    • Cohen, S.A.1    Müller, W.E.2
  • 107
    • 0024609214 scopus 로고
    • Action of piracetam and clonidine on different mitochondrial populations from hippocampus
    • Villa, R.F.; Arnaboldi, R.; Gorini, A.; Geroldi, D. Action of piracetam and clonidine on different mitochondrial populations from hippocampus. Il Farmaco Ed. Sc., 1989, 44, 215-226.
    • (1989) Il Farmaco Ed. Sc , vol.44 , pp. 215-226
    • Villa, R.F.1    Arnaboldi, R.2    Gorini, A.3    Geroldi, D.4
  • 109
    • 0023103252 scopus 로고
    • Changes of synaptosomal energy metabolism induceed by hypoxia during aging
    • Benzi, G.; Giuffrida, AM. Changes of synaptosomal energy metabolism induceed by hypoxia during aging. Neurochem. Res., 1987, 12, 149-157.
    • (1987) Neurochem. Res , vol.12 , pp. 149-157
    • Benzi, G.1    Giuffrida, A.M.2
  • 112
    • 38449108594 scopus 로고    scopus 로고
    • Vascular dementia: Pharmacological treatment approaches and perspectives
    • Baskys, A.; Hou, A.C. Vascular dementia: pharmacological treatment approaches and perspectives. Clin. Interv. Aging, 2007, 2, 327-335.
    • (2007) Clin. Interv. Aging , vol.2 , pp. 327-335
    • Baskys, A.1    Hou, A.C.2
  • 113
    • 0345872128 scopus 로고    scopus 로고
    • For the Memantine Study Group. Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil. A randomized controlled trial
    • Tariot, P.N.; Farlow, M. R.; Grossberg, G.T.; Graham, S. M.; McDonald, S.; Gergel, I. For the Memantine Study Group. Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil. A randomized controlled trial. JAMA, 2004, 291, 317-324.
    • (2004) JAMA , vol.291 , pp. 317-324
    • Tariot, P.N.1    Farlow, M.R.2    Grossberg, G.T.3    Graham, S.M.4    McDonald, S.5    Gergel, I.6
  • 115
    • 41149125591 scopus 로고    scopus 로고
    • Pharmacogenomics and therapeutic aspects in dementia
    • Cacabelos, R. Pharmacogenomics and therapeutic aspects in dementia. Eur. Arch. Psychiatry Clin. Neurosci., 2008, 258(Suppl 1), 28-47.
    • (2008) Eur. Arch. Psychiatry Clin. Neurosci , vol.258 , Issue.1 , pp. 28-47
    • Cacabelos, R.1
  • 116
    • 76349109248 scopus 로고    scopus 로고
    • Phosphodiesterase III inhibition promotes differentiation and survival of oligodendrocytes progenitors and enhances recuperation of ischemic white matter lesions in the adult mammalian brain
    • Miyamoto, N.; Tanaka, R.; Shimura, H.; Watanabe, T.; Mori, H.; Onodera, M.; Mochizuki, M.; Hattori, N.; Urabe, T. Phosphodiesterase III inhibition promotes differentiation and survival of oligodendrocytes progenitors and enhances recuperation of ischemic white matter lesions in the adult mammalian brain. J. Cerebr. Blood. Flow Metab., 2010, 30, 299-310.
    • (2010) J. Cerebr. Blood. Flow Metab , vol.30 , pp. 299-310
    • Miyamoto, N.1    Tanaka, R.2    Shimura, H.3    Watanabe, T.4    Mori, H.5    Onodera, M.6    Mochizuki, M.7    Hattori, N.8    Urabe, T.9
  • 118
    • 0029145084 scopus 로고
    • Are reactive oxygen species involved in Alzheimer's disease?
    • Benzi, G.; Moretti, A. Are reactive oxygen species involved in Alzheimer's disease? Neurobiol. Aging, 1995, 16, 661-674.
    • (1995) Neurobiol. Aging , vol.16 , pp. 661-674
    • Benzi, G.1    Moretti, A.2
  • 119
    • 67849097738 scopus 로고    scopus 로고
    • Oxidative stress in vascular dementia and Alzheimer's disease: A common pathology
    • Bennett, S.; Grant, M.M.; Aldred, S. Oxidative stress in vascular dementia and Alzheimer's disease: a common pathology. J. Alzheimers Dis., 2009, 17, 245-257.
    • (2009) J. Alzheimers Dis , vol.17 , pp. 245-257
    • Bennett, S.1    Grant, M.M.2    Aldred, S.3
  • 120
    • 0030976073 scopus 로고    scopus 로고
    • Pharmacology of lazaroids and brain energy metabolism: A review
    • Villa, R.F.; Gorini, A. Pharmacology of lazaroids and brain energy metabolism: a review. Pharmacol. Rev., 1997, 49, 99-136.
    • (1997) Pharmacol. Rev , vol.49 , pp. 99-136
    • Villa, R.F.1    Gorini, A.2
  • 122
    • 0026733793 scopus 로고
    • Preventable senility: A call for action against the vascular dementias
    • Hachinski, V. Preventable senility: a call for action against the vascular dementias. Lancet, 1992, 340, 645-647.
    • (1992) Lancet , vol.340 , pp. 645-647
    • Hachinski, V.1
  • 123
    • 42249089508 scopus 로고    scopus 로고
    • Diabetes and other vascular risk factors for dementia: Which factor matter most? A systematic review
    • Kloppenborg, R.P.; van den Berg, E.; Kappelle L.J.; Biessels, G.J. Diabetes and other vascular risk factors for dementia: which factor matter most? A systematic review. Eur. J. Pharmacol., 2008, 585, 97-108.
    • (2008) Eur. J. Pharmacol , vol.585 , pp. 97-108
    • Kloppenborg, R.P.1    van den Berg, E.2    Kappelle, L.J.3    Biessels, G.J.4
  • 124
    • 77949530671 scopus 로고    scopus 로고
    • Vascular pharmacotherapy and dementia
    • Piguet, O.; Garner, B. Vascular pharmacotherapy and dementia. Curr. Vasc. Pharmacol., 2010, 8, 44-50.
    • (2010) Curr. Vasc. Pharmacol , vol.8 , pp. 44-50
    • Piguet, O.1    Garner, B.2
  • 126
    • 34249803230 scopus 로고    scopus 로고
    • Longitudinal changes in cerebral blood flow in the older hypertensive brain
    • Beason-Held, L.L.; Moghekar, A.; Zondermann, A.B.; Kraut, M.A.; Resnick, S.M. Longitudinal changes in cerebral blood flow in the older hypertensive brain. Stroke, 2007, 38, 1766-1773.
    • (2007) Stroke , vol.38 , pp. 1766-1773
    • Beason-Held, L.L.1    Moghekar, A.2    Zondermann, A.B.3    Kraut, M.A.4    Resnick, S.M.5
  • 129
    • 22144451172 scopus 로고    scopus 로고
    • The age-dependent relation of blood pressure to cognitive function and dementia
    • Qiu, C.; Winblad, B.; Fratiglioni, L. The age-dependent relation of blood pressure to cognitive function and dementia. Lancet Neurol., 2005, 4, 487-499.
    • (2005) Lancet Neurol , vol.4 , pp. 487-499
    • Qiu, C.1    Winblad, B.2    Fratiglioni, L.3
  • 130
    • 33746042131 scopus 로고    scopus 로고
    • Progress in cardiovascular diseases: Cognitive function in essential hypertension
    • Birkenhager, W.H.; Staessen, J.S. Progress in cardiovascular diseases: cognitive function in essential hypertension. Prog. Cardiovasc. Dis., 2006, 49, 1-10.
    • (2006) Prog. Cardiovasc. Dis , vol.49 , pp. 1-10
    • Birkenhager, W.H.1    Staessen, J.S.2
  • 131
    • 60949108829 scopus 로고    scopus 로고
    • Blood pressure and the risk of dementia -A double edged sword
    • Kennelly, S.P.; Lawlor, B.A.; Kenny, R.A. Blood pressure and the risk of dementia -A double edged sword. Ageing Res. Rev., 2009, 8, 61-70.
    • (2009) Ageing Res. Rev , vol.8 , pp. 61-70
    • Kennelly, S.P.1    Lawlor, B.A.2    Kenny, R.A.3
  • 132
    • 0344837411 scopus 로고    scopus 로고
    • Association between dementia and midlife risk factors: The Radiation Effects Research Foundation Adult Health Study
    • Yamada, M.; Kasagi, F.; Sasaki, H.; Masunari, N.; Mimori, Y.; Suzuki, G. Association between dementia and midlife risk factors: the Radiation Effects Research Foundation Adult Health Study. J. Am. Geriatr. Soc., 2003, 51, 410-414.
    • (2003) J. Am. Geriatr. Soc , vol.51 , pp. 410-414
    • Yamada, M.1    Kasagi, F.2    Sasaki, H.3    Masunari, N.4    Mimori, Y.5    Suzuki, G.6
  • 133
    • 12744273863 scopus 로고    scopus 로고
    • Midlife cardiovascular risk factors and risk of dementia in late life
    • Whitmer, R.; Sidney, S.; Selby, J.; Claiborne Johnston, S.; Yaffe, K. Midlife cardiovascular risk factors and risk of dementia in late life. Neurology, 2005, 64, 277-281.
    • (2005) Neurology , vol.64 , pp. 277-281
    • Whitmer, R.1    Sidney, S.2    Selby, J.3    Claiborne Johnston, S.4    Yaffe, K.5
  • 141
    • 0346103691 scopus 로고    scopus 로고
    • Low blood pressure and the risk of dementia in very old individuals
    • Verghese, J.; Lipton, R.B.; Hall, C.B.; Kuslanski, G.; Katz, M.J. Low blood pressure and the risk of dementia in very old individuals. Neurology, 2003, 61, 1667-1672.
    • (2003) Neurology , vol.61 , pp. 1667-1672
    • Verghese, J.1    Lipton, R.B.2    Hall, C.B.3    Kuslanski, G.4    Katz, M.J.5
  • 142
  • 144
    • 8844225474 scopus 로고    scopus 로고
    • Hippocampal atrophy, whole brain volume, and white matter lesions in older hypertensive subjects
    • Wiseman, R.M.; Saxby, B.K.; Burton, E.J.; Barber, R.; Ford, G.A.; O'Brien, J.T. Hippocampal atrophy, whole brain volume, and white matter lesions in older hypertensive subjects. Neurology, 2004, 63, 1892-1897.
    • (2004) Neurology , vol.63 , pp. 1892-1897
    • Wiseman, R.M.1    Saxby, B.K.2    Burton, E.J.3    Barber, R.4    Ford, G.A.5    O'Brien, J.T.6
  • 148
    • 0141688134 scopus 로고    scopus 로고
    • Hypertension and cognitive function: Pathophysiologic effects of hypertension on the brain
    • Manolio, T.A.; Olson, J.; Longstreth, W.T. Hypertension and cognitive function: pathophysiologic effects of hypertension on the brain. Curr. Hypertens. Rep., 2003, 5, 255-261.
    • (2003) Curr. Hypertens. Rep , vol.5 , pp. 255-261
    • Manolio, T.A.1    Olson, J.2    Longstreth, W.T.3
  • 149
    • 0037111124 scopus 로고    scopus 로고
    • Protective effect of anti-hypertensive treatment on cognitive function in essential hypertension: Analysis of published clinical data
    • Amenta, F.; Mignini, F.; Rabbia, F.; Tomassoni, D.; Veglio, F. Protective effect of anti-hypertensive treatment on cognitive function in essential hypertension: analysis of published clinical data. J. Neurol. Sci., 2002, 203-204, 147-151.
    • (2002) J. Neurol. Sci , vol.203 , pp. 147-151
    • Amenta, F.1    Mignini, F.2    Rabbia, F.3    Tomassoni, D.4    Veglio, F.5
  • 151
    • 14844291328 scopus 로고    scopus 로고
    • Does blood pressure lowering treatment prevents dementia or cognitive decline in patients with cardiovascular and cerebral disease
    • Feigin, V.; Ratnasabapathy, Y.; Anderson, C. Does blood pressure lowering treatment prevents dementia or cognitive decline in patients with cardiovascular and cerebral disease? J. Neurol. Sci., 2005, 229-230, 151-155.
    • (2005) J. Neurol. Sci , vol.229 , pp. 151-155
    • Feigin, V.1    Ratnasabapathy, Y.2    Anderson, C.3
  • 152
    • 67651097487 scopus 로고    scopus 로고
    • Hypertension, dementia, and antihypertensive treatment: Implications for the very elderly
    • Peters, R.; Beckett, N. Hypertension, dementia, and antihypertensive treatment: implications for the very elderly. Curr. Hypertens. Rep., 2009, 11, 277-282.
    • (2009) Curr. Hypertens. Rep , vol.11 , pp. 277-282
    • Peters, R.1    Beckett, N.2
  • 154
    • 33646696167 scopus 로고    scopus 로고
    • Reducing the risk of dementia. Efficacy of long-term treatment of hypertension
    • Peila, R.; White, L.R.; Masaki, K.; Petrovitch, H.; Launer, L.J. Reducing the risk of dementia. Efficacy of long-term treatment of hypertension. Stroke, 2006, 37, 1165-1170.
    • (2006) Stroke , vol.37 , pp. 1165-1170
    • Peila, R.1    White, L.R.2    Masaki, K.3    Petrovitch, H.4    Launer, L.J.5
  • 157
    • 8644230145 scopus 로고    scopus 로고
    • Prevention of dementia: Lessons from SYSTEUR and PROGRESS
    • Hanon, O.; Forette, F. Prevention of dementia: lessons from SYSTEUR and PROGRESS. J. Neurol. Sci., 2004, 226, 71-74.
    • (2004) J. Neurol. Sci , vol.226 , pp. 71-74
    • Hanon, O.1    Forette, F.2
  • 158
    • 0038669268 scopus 로고    scopus 로고
    • Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease
    • The PROGRESS Collaborative Group
    • The PROGRESS Collaborative Group. Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease. Arch. Int. Med., 2003, 163, 1069-1075.
    • (2003) Arch. Int. Med , vol.163 , pp. 1069-1075
  • 159
    • 24944486283 scopus 로고    scopus 로고
    • Effects of blood pressure lowering on cerebral white matter hyperintensities in patients with stroke: The PROGRESS (Perindropil Protection Against Recurrent Stroke Study) Magnetic Resonance Imaging Substudy
    • Dufouil, C.; Chalmers, J.; Coskun, O.; Besançon, V.; Bousser, M.G.; Guillon, P.; MacMahon, S.; Mazoyer, B.; Neal, B.; Woodward, M.; Tzourio-Mazoyer, N.; Tzourio, C. Effects of blood pressure lowering on cerebral white matter hyperintensities in patients with stroke: the PROGRESS (Perindropil Protection Against Recurrent Stroke Study) Magnetic Resonance Imaging Substudy. Circulation, 2005, 112, 1644-1650.
    • (2005) Circulation , vol.112 , pp. 1644-1650
    • Dufouil, C.1    Chalmers, J.2    Coskun, O.3    Besançon, V.4    Bousser, M.G.5    Guillon, P.6    Macmahon, S.7    Mazoyer, B.8    Neal, B.9    Woodward, M.10    Tzourio-Mazoyer, N.11    Tzourio, C.12
  • 160
    • 46949106968 scopus 로고    scopus 로고
    • For the HYVET investigators. Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): A double-blind, placebo controlled trial
    • Peters, R.; Beckett, N.; Forette, F.; Tuomilehto, J.; Clarke, R.; Ritchie, C.; Waldman, A.; Walton, I.; Poulter, R.; Ma, S.; Comsa, M.; Burch, L.; Fletcher, A.; Bulpitt, C.; For the HYVET investigators. Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial. Lancet Neurol., 2008, 7, 683-689.
    • (2008) Lancet Neurol , vol.7 , pp. 683-689
    • Peters, R.1    Beckett, N.2    Forette, F.3    Tuomilehto, J.4    Clarke, R.5    Ritchie, C.6    Waldman, A.7    Walton, I.8    Poulter, R.9    Ma, S.10    Comsa, M.11    Burch, L.12    Fletcher, A.13    Bulpitt, C.14
  • 161
    • 23744468024 scopus 로고    scopus 로고
    • Effect of baseline cognitive function and antihypertensive treatment on cognitive and cardiovascular outcomes: Study on cognition and Prognosis in the Elderly (SCOPE)
    • Skoog, I.; Lithell, H.; Hansson, L.; Elmfeldt, D.; Hofman, A.; Olofsson, B.; Trenkwalder, P.; Zanchetti, A. Effect of baseline cognitive function and antihypertensive treatment on cognitive and cardiovascular outcomes: study on cognition and Prognosis in the Elderly (SCOPE). Am. J. Hypertens., 2005, 18, 1052-1059.
    • (2005) Am. J. Hypertens , vol.18 , pp. 1052-1059
    • Skoog, I.1    Lithell, H.2    Hansson, L.3    Elmfeldt, D.4    Hofman, A.5    Olofsson, B.6    Trenkwalder, P.7    Zanchetti, A.8
  • 162
    • 71749121407 scopus 로고    scopus 로고
    • Does use of antihypertensive drugs affect the incidence or progression of dementia? A systematic review
    • Shah, K.; Qureshi, S.U.; Johnson, M.; Parikh, N.; Schulz, P.E.; Kunik, M.E. Does use of antihypertensive drugs affect the incidence or progression of dementia? A systematic review. Am. J. Geriatr. Pharmacother., 2009, 7, 250-261.
    • (2009) Am. J. Geriatr. Pharmacother , vol.7 , pp. 250-261
    • Shah, K.1    Qureshi, S.U.2    Johnson, M.3    Parikh, N.4    Schulz, P.E.5    Kunik, M.E.6
  • 164
    • 74949089743 scopus 로고    scopus 로고
    • Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia
    • McGuiness, B.; Todd, S.; Passmore, P.; Bullock, R. Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia. Cochrane Database Syst. Rev., 2009, 4, CD004034.
    • (2009) Cochrane Database Syst. Rev , vol.4
    • McGuiness, B.1    Todd, S.2    Passmore, P.3    Bullock, R.4
  • 166
    • 37549044212 scopus 로고    scopus 로고
    • Use of calcium antagonists and cognitive decline in old age. The Leiden 85-plus study
    • Trompet, S.; Westendorp, R.G.J.; Kamper, A.M.; de Craen, A.J.M. Use of calcium antagonists and cognitive decline in old age. The Leiden 85-plus study. Neurobiol. Aging, 2008, 29, 306-308.
    • (2008) Neurobiol. Aging , vol.29 , pp. 306-308
    • Trompet, S.1    Westendorp, R.G.J.2    Kamper, A.M.3    de Craen, A.J.M.4
  • 167
    • 33748543254 scopus 로고    scopus 로고
    • Relationship between antihypertensive drug therapy and cognitive function in elderly hypertensive patients with memory complaints
    • Hanon, O.; Pequignot, R.; Seux, M.L.; Lenoir, H.; Bune, A.; Rigaud, A.S.; Forette, F.; Girerd, X. Relationship between antihypertensive drug therapy and cognitive function in elderly hypertensive patients with memory complaints. J. Hypertens., 2006, 24, 2101-2107.
    • (2006) J. Hypertens , vol.24 , pp. 2101-2107
    • Hanon, O.1    Pequignot, R.2    Seux, M.L.3    Lenoir, H.4    Bune, A.5    Rigaud, A.S.6    Forette, F.7    Girerd, X.8
  • 168
    • 0028651951 scopus 로고
    • Calcium hypothesis of Alzheimer's disease and brain aging
    • Khachaturian, Z.S. Calcium hypothesis of Alzheimer's disease and brain aging. Ann. NY Acad. Sci., 1994, 747, 1-11.
    • (1994) Ann. NY Acad. Sci , vol.747 , pp. 1-11
    • Khachaturian, Z.S.1
  • 169
    • 0036830947 scopus 로고    scopus 로고
    • Calcium dyshomeostasis and intracellular signaling in Alzheimer's disease
    • LaFerla, F.M. Calcium dyshomeostasis and intracellular signaling in Alzheimer's disease. Nat. Rev. Neurosci., 2002, 3, 862-872.
    • (2002) Nat. Rev. Neurosci , vol.3 , pp. 862-872
    • LaFerla, F.M.1
  • 170
    • 0043026941 scopus 로고    scopus 로고
    • Arterial hypertension and brain damage-evidence from animal models (review)
    • Amenta, F.; Di Tullio, M.A.; Tomassoni, D. Arterial hypertension and brain damage-evidence from animal models (review). Clin. Exp. Hypertens., 2003, 25, 359-380.
    • (2003) Clin. Exp. Hypertens , vol.25 , pp. 359-380
    • Amenta, F.1    Di Tullio, M.A.2    Tomassoni, D.3
  • 171
    • 0036496910 scopus 로고    scopus 로고
    • The role of angiotensin II in cognition and behaviour
    • Gard, P.R. The role of angiotensin II in cognition and behaviour. Eur. J. Pharmacol., 2002, 438, 1-14.
    • (2002) Eur. J. Pharmacol , vol.438 , pp. 1-14
    • Gard, P.R.1
  • 172
    • 0032709918 scopus 로고    scopus 로고
    • Comparison of losartan and hydrochlorothiazide on cognitive function and quality of life in hypertensive patients
    • Tedesco, M.A.; Ratti, G.; Mennella, S.; Manzo, G.; Grieco, M.; Rainone, A.C.; Iarussi, D.; Iacono, A. Comparison of losartan and hydrochlorothiazide on cognitive function and quality of life in hypertensive patients. Am. J. Hypertens., 1999, 12, 1130-1134.
    • (1999) Am. J. Hypertens , vol.12 , pp. 1130-1134
    • Tedesco, M.A.1    Ratti, G.2    Mennella, S.3    Manzo, G.4    Grieco, M.5    Rainone, A.C.6    Iarussi, D.7    Iacono, A.8
  • 173
  • 175
    • 31344454633 scopus 로고    scopus 로고
    • Antihypertensive agents for aging patients who are at risk for cognitive dysfunction
    • Hajjar, I.; Keown, M.; Frost, B. Antihypertensive agents for aging patients who are at risk for cognitive dysfunction. Curr. Hypertens. Rep., 2005, 7, 466-473.
    • (2005) Curr. Hypertens. Rep , vol.7 , pp. 466-473
    • Hajjar, I.1    Keown, M.2    Frost, B.3
  • 177
    • 33745515438 scopus 로고    scopus 로고
    • Angiotensin receptor blockers and cerebral protection in stroke
    • Thöne-Reineke, C.; Steckelings, U.M.; Unger, T. Angiotensin receptor blockers and cerebral protection in stroke. J. Hypertens., 2006, 24(Suppl. 1), S115-S121.
    • (2006) J. Hypertens , vol.24 , Issue.1
    • Thöne-Reineke, C.1    Steckelings, U.M.2    Unger, T.3
  • 178
    • 34548182310 scopus 로고    scopus 로고
    • Usefulness of ARBs and ACE inhibitors in the prevention of vascular dementia in the elderly
    • Hanes, D. S.; Weir, M.R. Usefulness of ARBs and ACE inhibitors in the prevention of vascular dementia in the elderly. Am. J. Geriatr. Cardiol., 2007, 16, 175-182.
    • (2007) Am. J. Geriatr. Cardiol , vol.16 , pp. 175-182
    • Hanes, D.S.1    Weir, M.R.2
  • 180
    • 59849091253 scopus 로고    scopus 로고
    • Continuous activation of renin-angiotensin systems impairs cognitive function in renin/angiotensin transgenic mice
    • Inaba, S.; Iwai, M.; Furono, M.; Tomono, Y.; Kanno, H.; Senba, I.; Okayama, H.; Mogi, M.; Higaki, J.; Horiuchi, M. Continuous activation of renin-angiotensin systems impairs cognitive function in renin/angiotensin transgenic mice. Hypertension, 2009, 53(Part 2), 356-362.
    • (2009) Hypertension , vol.53 , Issue.2 , pp. 356-362
    • Inaba, S.1    Iwai, M.2    Furono, M.3    Tomono, Y.4    Kanno, H.5    Senba, I.6    Okayama, H.7    Mogi, M.8    Higaki, J.9    Horiuchi, M.10
  • 182
    • 77956267257 scopus 로고    scopus 로고
    • Losartan improved respiratory function and coenzyme Q content in brain mitochondria of young spontaneously hypertensive rats
    • Sumbalová, Z.; Kucharská, J.; Kristek, F. Losartan improved respiratory function and coenzyme Q content in brain mitochondria of young spontaneously hypertensive rats. Cell Mol. Neurobiol. 2010, 30, 751-758.
    • (2010) Cell Mol. Neurobiol , vol.30 , pp. 751-758
    • Sumbalová, Z.1    Kucharská, J.2    Kristek, F.3
  • 183
    • 33845957039 scopus 로고    scopus 로고
    • Effect of chronic angiotensin converting enzyme inhibition on spatial memory and anxiety-like behaviours in rats
    • Jenkins, T.A.; Chai, S.Y. Effect of chronic angiotensin converting enzyme inhibition on spatial memory and anxiety-like behaviours in rats. Neurobiol. Learn. Mem., 2007, 87, 218-224.
    • (2007) Neurobiol. Learn. Mem , vol.87 , pp. 218-224
    • Jenkins, T.A.1    Chai, S.Y.2
  • 187
  • 188
    • 67749114631 scopus 로고    scopus 로고
    • Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later
    • Solomon, A.; Kivipelto, M.; Wolozin, B.; Zhou, J.; Whitmer, R.A. Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later. Dement. Geriatr. Cogn. Disord., 2009, 28, 75-80.
    • (2009) Dement. Geriatr. Cogn. Disord , vol.28 , pp. 75-80
    • Solomon, A.1    Kivipelto, M.2    Wolozin, B.3    Zhou, J.4    Whitmer, R.A.5
  • 190
    • 33846061128 scopus 로고    scopus 로고
    • Twenty-six-year change in total cholesterol levels and incident dementia
    • Steward, R.; White, L.R.; Xue, Q-L.; Launer, L.J. Twenty-six-year change in total cholesterol levels and incident dementia. Arch. Neurol., 2007, 64, 103-107.
    • (2007) Arch. Neurol , vol.64 , pp. 103-107
    • Steward, R.1    White, L.R.2    Xue, Q.-L.3    Launer, L.J.4
  • 192
    • 2442489033 scopus 로고    scopus 로고
    • Relation of plasma lipids to Alzheimer disease and vascular dementia
    • Reitz, C.; Tang, M-X.; Luchsinger, J.; Mayeux, R. Relation of plasma lipids to Alzheimer disease and vascular dementia. Arch. Neurol., 2004, 61, 705-714.
    • (2004) Arch. Neurol , vol.61 , pp. 705-714
    • Reitz, C.1    Tang, M.-X.2    Luchsinger, J.3    Mayeux, R.4
  • 193
  • 194
  • 199
    • 33846450284 scopus 로고    scopus 로고
    • Prevention of stroke and dementia by statin therapy: Experimental and clinical evidence of their pleiotropic effects
    • Miida, T.; Takahashi, A.; Ikeuchi, T. Prevention of stroke and dementia by statin therapy: experimental and clinical evidence of their pleiotropic effects. Pharmacol. Ther., 2007, 113, 378-393.
    • (2007) Pharmacol. Ther , vol.113 , pp. 378-393
    • Miida, T.1    Takahashi, A.2    Ikeuchi, T.3
  • 200
    • 42449117901 scopus 로고    scopus 로고
    • Reduction in blood pressure with statins: Results from the UCSD Statin Study, a randomized trial
    • Golomb, B.A.; Dimsdale, J.E.; White, H.L.; Ritchie, J.B.; Criqui, M.H. Reduction in blood pressure with statins: results from the UCSD Statin Study, a randomized trial. Arch. Intern. Med., 2008, 168, 721-727.
    • (2008) Arch. Intern. Med , vol.168 , pp. 721-727
    • Golomb, B.A.1    Dimsdale, J.E.2    White, H.L.3    Ritchie, J.B.4    Criqui, M.H.5
  • 201
  • 202
    • 67649252917 scopus 로고    scopus 로고
    • Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study
    • Cramer, C.; Haan, M.N.; Galea, S.; Langa, KM.; Kalbfleisch, J.D. Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study. Neurology, 2008, 71, 344-350.
    • (2008) Neurology , vol.71 , pp. 344-350
    • Cramer, C.1    Haan, M.N.2    Galea, S.3    Langa, K.M.4    Kalbfleisch, J.D.5
  • 203
    • 33847389770 scopus 로고    scopus 로고
    • Prevention and treatment of dementia or Alzheimer's disease by statins: A meta-analysis
    • Zhou, B.; Teramukai, S.; Fukushima, M. Prevention and treatment of dementia or Alzheimer's disease by statins: a meta-analysis. Dement. Geriatr. Cogn. Disord., 2007, 23, 194-201.
    • (2007) Dement. Geriatr. Cogn. Disord , vol.23 , pp. 194-201
    • Zhou, B.1    Teramukai, S.2    Fukushima, M.3
  • 205
    • 33745741303 scopus 로고    scopus 로고
    • Epidemiological and clinical trials evidence about a preventive role for statins in Alzheimer's disease
    • Rockwood, K. Epidemiological and clinical trials evidence about a preventive role for statins in Alzheimer's disease. Acta Neurol. Scand., 2006, 114(Suppl. 185), 71-77.
    • (2006) Acta Neurol. Scand , vol.114 , Issue.SUPPL. 185 , pp. 71-77
    • Rockwood, K.1
  • 206
    • 14844330642 scopus 로고    scopus 로고
    • A study of statin use in the prevention of cognitive impairment of vascular origin in the UK
    • Suribhatla, S.; Dennis, M.S.; Potter, J.F. A study of statin use in the prevention of cognitive impairment of vascular origin in the UK. J. Neurol. Sci., 2005, 229-230, 147-150
    • (2005) J. Neurol. Sci , vol.229-230 , pp. 147-150
    • Suribhatla, S.1    Dennis, M.S.2    Potter, J.F.3
  • 207
    • 51349101107 scopus 로고    scopus 로고
    • Ameliorative role of atorvastatin and pitavastatin in L-methionine induced vascular dementia in rats
    • Koladiya, R.U.; Jaggi, A.S.; Singh, N.; Sharma, BK. Ameliorative role of atorvastatin and pitavastatin in L-methionine induced vascular dementia in rats. BMC Pharmacol., 2008, 8, 14.
    • (2008) BMC Pharmacol , vol.8 , pp. 14
    • Koladiya, R.U.1    Jaggi, A.S.2    Singh, N.3    Sharma, B.K.4
  • 208
    • 3142735789 scopus 로고    scopus 로고
    • The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke and death: A population-based study of 13,000 men and women with 20 years of follow-up
    • Almdal, T.; Scharling, H.; Jensen, J.S.; Vestergaard, H. The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke and death: a population-based study of 13,000 men and women with 20 years of follow-up. Arch. Int. Med., 2004, 164, 1422-1426.
    • (2004) Arch. Int. Med , vol.164 , pp. 1422-1426
    • Almdal, T.1    Scharling, H.2    Jensen, J.S.3    Vestergaard, H.4
  • 210
    • 34548711907 scopus 로고    scopus 로고
    • Type 2 diabetes and risk of cogniitive impairment and dementia
    • Whitmer, R.A. Type 2 diabetes and risk of cogniitive impairment and dementia. Curr. Neurol. Neurosci. Rep., 2007, 7, 373-380.
    • (2007) Curr. Neurol. Neurosci. Rep , vol.7 , pp. 373-380
    • Whitmer, R.A.1
  • 211
    • 28444491100 scopus 로고    scopus 로고
    • Cognitive decline and dementia in diabetes-systematic overview of prospective observational studies
    • Cukierman, T.; Gerstein, H.C.; Williamson, J.D. Cognitive decline and dementia in diabetes-systematic overview of prospective observational studies. Diabetologia, 2005, 48, 2460-2469.
    • (2005) Diabetologia , vol.48 , pp. 2460-2469
    • Cukierman, T.1    Gerstein, H.C.2    Williamson, J.D.3
  • 215
    • 0036973393 scopus 로고    scopus 로고
    • Diabetes mellitus and the risk of dementia, Alzheimer's disease and vascular cognitive impairment in the Canadian Study of Health and Aging
    • MacKnight, C.; Rockwood, K.; Awalt, E.; McDowell, I. Diabetes mellitus and the risk of dementia, Alzheimer's disease and vascular cognitive impairment in the Canadian Study of Health and Aging. Dement. Geriatr. Cogn. Disord., 2002, 14, 77-83.
    • (2002) Dement. Geriatr. Cogn. Disord , vol.14 , pp. 77-83
    • MacKnight, C.1    Rockwood, K.2    Awalt, E.3    McDowell, I.4
  • 216
    • 0035479310 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort
    • Luchsinger, J.A.; Tang, M-X.; Stern, Y., Shea, S.; Mayeux, R. Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort. Am. J. Epidemiol., 2001, 154, 635-641.
    • (2001) Am. J. Epidemiol , vol.154 , pp. 635-641
    • Luchsinger, J.A.1    Tang, M.-X.2    Stern, Y.3    Shea, S.4    Mayeux, R.5
  • 217
    • 0036227542 scopus 로고    scopus 로고
    • Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies - The Honolulu-Asia Aging Study
    • Peila, R.; Rodriguez, B.L.; Launer, L.J. Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies - The Honolulu-Asia Aging Study. Diabetes, 2002, 51, 1256-1262.
    • (2002) Diabetes , vol.51 , pp. 1256-1262
    • Peila, R.1    Rodriguez, B.L.2    Launer, L.J.3
  • 218
    • 5344237420 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of dementia in the Kungsholmen project - A 6-year follow-up study
    • Xu, W.L.; Qiu, C.X.; Wahlin, A.; Winblad, B.; Fratiglioni, L. Diabetes mellitus and risk of dementia in the Kungsholmen project - A 6-year follow-up study. Neurology, 2004, 63, 1181-1186.
    • (2004) Neurology , vol.63 , pp. 1181-1186
    • Xu, W.L.1    Qiu, C.X.2    Wahlin, A.3    Winblad, B.4    Fratiglioni, L.5
  • 219
    • 0036759508 scopus 로고    scopus 로고
    • Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: A populationbased study of the oldest old
    • Hassing, L.B.; Johansson, B.; Nilsson, S.E.; Berg, S.; Pedersen, N.L.; Gatz, M.; McCleearn, G. Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: a populationbased study of the oldest old. Int. Psychogeriatr., 2002, 14, 239-248.
    • (2002) Int. Psychogeriatr , vol.14 , pp. 239-248
    • Hassing, L.B.1    Johansson, B.2    Nilsson, S.E.3    Berg, S.4    Pedersen, N.L.5    Gatz, M.6    McCleearn, G.7
  • 220
    • 63249111096 scopus 로고    scopus 로고
    • Mid- and late-life diabetes in relation to the risk of dementia: A population-based twin study
    • Xu, W.; Qiu, C.; Gatz, M.; Pedersen, N.L.; Johansson, B.; Fratiglioni, L. Mid- and late-life diabetes in relation to the risk of dementia: a population-based twin study. Diabetes, 2009, 58, 71-77.
    • (2009) Diabetes , vol.58 , pp. 71-77
    • Xu, W.1    Qiu, C.2    Gatz, M.3    Pedersen, N.L.4    Johansson, B.5    Fratiglioni, L.6
  • 221
    • 1542373533 scopus 로고    scopus 로고
    • Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years
    • Logroscino, G.; Kang, J.H.; Grodstein, F. Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years. BMJ, 2004, 328, 548-551.
    • (2004) BMJ , vol.328 , pp. 548-551
    • Logroscino, G.1    Kang, J.H.2    Grodstein, F.3
  • 223
  • 225
    • 33745265189 scopus 로고    scopus 로고
    • PPARγ agonists as new therapeutic agents for the treatment of Alzheimer's disease
    • Landreth, G. PPARγ agonists as new therapeutic agents for the treatment of Alzheimer's disease. Exp. Neurol., 2006, 199, 245-248.
    • (2006) Exp. Neurol , vol.199 , pp. 245-248
    • Landreth, G.1
  • 226
    • 64749114159 scopus 로고    scopus 로고
    • Hypoglycemic episodes and risk of dementia in older patients with Type 2 diabetes mellitus
    • Whitmer, R.A.; Karter, A.J.; Yaffe, K.; Quesenberry Jr. C.P.; Selby, J.V. Hypoglycemic episodes and risk of dementia in older patients with Type 2 diabetes mellitus. JAMA, 2009, 301, 1565-1572.
    • (2009) JAMA , vol.301 , pp. 1565-1572
    • Whitmer, R.A.1    Karter, A.J.2    Yaffe, K.3    Quesenberry, C.P.4    Selby, J.V.5
  • 227
    • 42049107348 scopus 로고    scopus 로고
    • Telmisartan, ramipril, or both in patients at high risk for vascular events
    • The ONTARGET Investigations
    • The ONTARGET Investigations. Telmisartan, ramipril, or both in patients at high risk for vascular events. N. Engl. J. Med., 2008, 358, 1547-1559.
    • (2008) N. Engl. J. Med , vol.358 , pp. 1547-1559
  • 229
    • 70349686490 scopus 로고    scopus 로고
    • Losartan metabolite EXP3179: An AT1-receptorindependent treatment strategy for patients with the metabolic syndrome?
    • Rossi, G.P. Losartan metabolite EXP3179: an AT1-receptorindependent treatment strategy for patients with the metabolic syndrome? Hypertension, 2009, 54, 710-712.
    • (2009) Hypertension , vol.54 , pp. 710-712
    • Rossi, G.P.1
  • 230
    • 0037459810 scopus 로고    scopus 로고
    • Angiotensin converting enzyme inhibition partially prevents deficits in water maze performance, hippocampal synaptic plasticity and cerebral blood flow in streptozotocin-diabetic rats
    • Manschot, S.M.; Biessels, G.J., Cameron, N.E.; Cotter, M.A.; Kamal, A.; Kappelle, L.J.; Gispen, W.H. Angiotensin converting enzyme inhibition partially prevents deficits in water maze performance, hippocampal synaptic plasticity and cerebral blood flow in streptozotocin-diabetic rats. Brain Res., 2003, 966, 274-282.
    • (2003) Brain Res , vol.966 , pp. 274-282
    • Manschot, S.M.1    Biessels, G.J.2    Cameron, N.E.3    Cotter, M.A.4    Kamal, A.5    Kappelle, L.J.6    Gispen, W.H.7
  • 231
  • 232
    • 33745940760 scopus 로고    scopus 로고
    • Adiposity indices and dementia
    • Gustafson, D. Adiposity indices and dementia. Lancet Neurol., 2006, 5, 713-720.
    • (2006) Lancet Neurol , vol.5 , pp. 713-720
    • Gustafson, D.1
  • 233
    • 33947589960 scopus 로고    scopus 로고
    • The risk of dementia with increased body mass
    • Gorospe, E.C.; Dave, J.K. The risk of dementia with increased body mass. Age Ageing, 2007, 36, 23-29.
    • (2007) Age Ageing , vol.36 , pp. 23-29
    • Gorospe, E.C.1    Dave, J.K.2
  • 235
    • 13444302233 scopus 로고    scopus 로고
    • Body mass index, other cardiovascular risk factors, and hospitalization for dementia
    • Rosengren, A.; Skoog, I.; Gustafson, D.; Wilhelmsen, L. Body mass index, other cardiovascular risk factors, and hospitalization for dementia. Arch. Int. Med., 2005, 165, 321-326.
    • (2005) Arch. Int. Med , vol.165 , pp. 321-326
    • Rosengren, A.1    Skoog, I.2    Gustafson, D.3    Wilhelmsen, L.4
  • 238
    • 34548126495 scopus 로고    scopus 로고
    • Incident dementia in women is preceded by weight loss by at least a decade
    • Knopman, D.S.; Edland, S.D.; Cha, R.H.; Petersen, R.C.; Rocca, W.A. Incident dementia in women is preceded by weight loss by at least a decade. Neurology, 2007, 69, 739-746.
    • (2007) Neurology , vol.69 , pp. 739-746
    • Knopman, D.S.1    Edland, S.D.2    Cha, R.H.3    Petersen, R.C.4    Rocca, W.A.5
  • 243
    • 28444459843 scopus 로고    scopus 로고
    • Studies of the effects of high fat diets on cognitive function in a rat model
    • Winocur, G.; Greenwood, C.E. Studies of the effects of high fat diets on cognitive function in a rat model. Neurobiol. Aging, 2005, 26S, S46-S49.
    • (2005) Neurobiol. Aging , vol.26 S
    • Winocur, G.1    Greenwood, C.E.2
  • 244
    • 27744486073 scopus 로고    scopus 로고
    • Memory impairment in obese Zucker rats: An investigation of cognitive function in an animal model of insulin resistance and obesity
    • Winocur, G.; Greenwood, C.E.; Piroli, G.C.; Grillo, C.A.; Reznikov, L.R.; Reagan, L.P.; McEwen, B.S. Memory impairment in obese Zucker rats: an investigation of cognitive function in an animal model of insulin resistance and obesity. Behav. Neurosci., 2005, 119, 1389-1395.
    • (2005) Behav. Neurosci , vol.119 , pp. 1389-1395
    • Winocur, G.1    Greenwood, C.E.2    Piroli, G.C.3    Grillo, C.A.4    Reznikov, L.R.5    Reagan, L.P.6    McEwen, B.S.7
  • 245
    • 0033984631 scopus 로고    scopus 로고
    • Effects of sibutramine alone and with alcohol on cognitive function in healthy volunteers
    • Wesnes, KA.; Garratt, C.; Wickens, M.; Gudgeon, A.; Oliver, S. Effects of sibutramine alone and with alcohol on cognitive function in healthy volunteers. Br. J. Clin. Pharmacol., 2000, 49, 110-117.
    • (2000) Br. J. Clin. Pharmacol , vol.49 , pp. 110-117
    • Wesnes, K.A.1    Garratt, C.2    Wickens, M.3    Gudgeon, A.4    Oliver, S.5
  • 246
    • 33645287272 scopus 로고    scopus 로고
    • 3 receptor antagonists: Preclinical promise for treating obesity and cognitive disorders
    • Esbenshade, T.A.; Fox, G.B.; Cowart, M.D. Histamine H3 receptor antagonists: preclinical promise for treating obesity and cognitive disorders. Mol. Interv., 2006, 6, 77-88.
    • (2006) Mol. Interv , vol.6 , pp. 77-88
    • Esbenshade, T.A.1    Fox, G.B.2    Cowart, M.D.3
  • 247
    • 38549144692 scopus 로고    scopus 로고
    • Selective 5-HT6 receptor ligands: Progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders
    • Heal, D.J.; Smith, S.L.; Fisas, A.; Codony, X.; Buschmann, H. Selective 5-HT6 receptor ligands: progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders. Pharmacol. Ther., 2008, 117, 207-231.
    • (2008) Pharmacol. Ther , vol.117 , pp. 207-231
    • Heal, D.J.1    Smith, S.L.2    Fisas, A.3    Codony, X.4    Buschmann, H.5
  • 248
    • 33745758241 scopus 로고    scopus 로고
    • Inflammation and dementia: Epidemiologic evidence
    • Peila, R.; Launer, L.J. Inflammation and dementia: epidemiologic evidence. Acta Neurol. Scand., 2006, 114(Suppl. 185), 102-106.
    • (2006) Acta Neurol. Scand , vol.114 , Issue.SUPPL. 185 , pp. 102-106
    • Peila, R.1    Launer, L.J.2
  • 249
    • 0036321773 scopus 로고    scopus 로고
    • Early inflammation and dementia: A 25-year follow-up of the Honolulu-Asia Aging Study
    • Schmidt, R.; Schmidt, H.; Curb, J.D.; Masaki, K.; White, L.R.; Launer L.J. Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study. Ann. Neurol., 2002, 52, 168-174.
    • (2002) Ann. Neurol , vol.52 , pp. 168-174
    • Schmidt, R.1    Schmidt, H.2    Curb, J.D.3    Masaki, K.4    White, L.R.5    Launer, L.J.6
  • 253
    • 33644663637 scopus 로고    scopus 로고
    • Fibrinogen is associated with an increased risk of Alzheimer disease and vascular dementia
    • Van Oijen, M.; Witteman, J.C.; Hofman, A.; Koudstaal, P.J.; Breteler, M.M.B. Fibrinogen is associated with an increased risk of Alzheimer disease and vascular dementia. Stroke, 2005, 36, 2637-2641.
    • (2005) Stroke , vol.36 , pp. 2637-2641
    • van Oijen, M.1    Witteman, J.C.2    Hofman, A.3    Koudstaal, P.J.4    Breteler, M.M.B.5
  • 254
    • 0027298505 scopus 로고
    • Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1b
    • Lee, S.C.; Liu, W.; Dickson, D.W.; Brosnan, C.F.; Barman, J.W. Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1b. J. Immunol. 1993, 150, 2659-2667.
    • (1993) J. Immunol , vol.150 , pp. 2659-2667
    • Lee, S.C.1    Liu, W.2    Dickson, D.W.3    Brosnan, C.F.4    Barman, J.W.5
  • 255
    • 3843121075 scopus 로고    scopus 로고
    • Elevated interleukin-6 leveles in cerebrospinal fluid of vascular dementia patients
    • Wada-Isoe, K.; Wakutani, Y.; Urakami, K.; Nakashima, K. Elevated interleukin-6 leveles in cerebrospinal fluid of vascular dementia patients. Acta Neurol. Scand., 2004, 110, 124-127.
    • (2004) Acta Neurol. Scand , vol.110 , pp. 124-127
    • Wada-Isoe, K.1    Wakutani, Y.2    Urakami, K.3    Nakashima, K.4
  • 257
    • 0025362271 scopus 로고
    • Intracerebroventricular injection of interleukin 1 induces high circulating levels of interleukin 6
    • De Simoni, M.G.; Sironi, M.; De Luigi, A.; Manfridi, A.; Mantovani, A.; Grezzi, P. Intracerebroventricular injection of interleukin 1 induces high circulating levels of interleukin 6. J. Exp. Med., 1990, 171, 1773-1778.
    • (1990) J. Exp. Med , vol.171 , pp. 1773-1778
    • de Simoni, M.G.1    Sironi, M.2    de Luigi, A.3    Manfridi, A.4    Mantovani, A.5    Grezzi, P.6
  • 260
    • 0038813958 scopus 로고    scopus 로고
    • Regular use of nonsteroidal anti-inflammatory drugs and cognitive function in aging women
    • Kang, J.H.; Grodstein, F. Regular use of nonsteroidal anti-inflammatory drugs and cognitive function in aging women. Neurology, 2003, 60, 1591-1597.
    • (2003) Neurology , vol.60 , pp. 1591-1597
    • Kang, J.H.1    Grodstein, F.2
  • 264
    • 33646182855 scopus 로고    scopus 로고
    • Use of first- and secondcyclooxygenase- 2-selective nonsteroidal anti-inflammatory drugs and risk of acute myocardial infarction
    • Andersohn, F.; Suissa, S.; Garbe, E. Use of first- and secondcyclooxygenase- 2-selective nonsteroidal anti-inflammatory drugs and risk of acute myocardial infarction. Circulation, 2006, 113, 1950-1957.
    • (2006) Circulation , vol.113 , pp. 1950-1957
    • Andersohn, F.1    Suissa, S.2    Garbe, E.3
  • 265
    • 33745934320 scopus 로고    scopus 로고
    • Cyclooxygenase nonsteroidal antiinflammatory drugs and the risk of ischemic stroke
    • Andersohn, F.; Schade, R.; Suissa, S.; Garbe, E. Cyclooxygenase nonsteroidal antiinflammatory drugs and the risk of ischemic stroke. Stroke, 2006, 37, 1725-1730.
    • (2006) Stroke , vol.37 , pp. 1725-1730
    • Andersohn, F.1    Schade, R.2    Suissa, S.3    Garbe, E.4
  • 267
    • 0037411495 scopus 로고    scopus 로고
    • Does aspirin or other NSAIDs reduce the risk of cognitive decline in elderly persons? Results from a population-based study
    • Jonker, C.; Comijs, H.C.; Smit, J.H. Does aspirin or other NSAIDs reduce the risk of cognitive decline in elderly persons? Results from a population-based study. Neurobiol. Aging, 2003, 24, 583-588.
    • (2003) Neurobiol. Aging , vol.24 , pp. 583-588
    • Jonker, C.1    Comijs, H.C.2    Smit, J.H.3
  • 268
    • 0030938396 scopus 로고    scopus 로고
    • Is there any evidence for a protective effect of antithrombotic medication on cognitive function in men at risk of cardiovascular disease? Some preliminary findings
    • Richards, M.; Meade, T.W.; Pearl, S.; Brennan, P.J.; Mann, A.H. Is there any evidence for a protective effect of antithrombotic medication on cognitive function in men at risk of cardiovascular disease? Some preliminary findings. J. Neurol. Neurosurg. Psychiat., 1997, 62, 269-272.
    • (1997) J. Neurol. Neurosurg. Psychiat , vol.62 , pp. 269-272
    • Richards, M.1    Meade, T.W.2    Pearl, S.3    Brennan, P.J.4    Mann, A.H.5
  • 269
    • 34249293021 scopus 로고    scopus 로고
    • Low dose aspirin and cognitive function in the women's health study cognitive cohort
    • Kang, J.H.; Cook, N.; Manson, J.; Buring, J.E.; Grodstein, F. Low dose aspirin and cognitive function in the women's health study cognitive cohort. BMJ, 2007, 334, 987.
    • (2007) BMJ , vol.334 , pp. 987
    • Kang, J.H.1    Cook, N.2    Manson, J.3    Buring, J.E.4    Grodstein, F.5
  • 270
    • 85057634896 scopus 로고    scopus 로고
    • On behalf of AAA Trialists. Low dose aspirin and cognitive function in middle aged to elderly adults: Randomised controlled trial
    • Price, J.F.; Steward, M.C.; Deary, I.J.; Murray, G.D.; Sandercock, P.; Butcher, I.; Fowkes, F.G.R. On behalf of AAA Trialists. Low dose aspirin and cognitive function in middle aged to elderly adults: randomised controlled trial. BMJ, 2008, 337, 198.
    • (2008) BMJ , vol.337 , pp. 198
    • Price, J.F.1    Steward, M.C.2    Deary, I.J.3    Murray, G.D.4    Sandercock, P.5    Butcher, I.6    Fowkes, F.G.R.7
  • 272
    • 34249948187 scopus 로고    scopus 로고
    • Metabolic syndrome and cognitive disorders. Is the sum greater than its parts?
    • Yaffe, K. Metabolic syndrome and cognitive disorders. Is the sum greater than its parts? Alzheimer Dis. Assoc. Disord., 2007, 21, 167-171.
    • (2007) Alzheimer Dis. Assoc. Disord , vol.21 , pp. 167-171
    • Yaffe, K.1
  • 273
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among US adults: Findings from the third National Health and Nutrition Examination Survey
    • Ford, E.S.; Giles, W.H.; Dietz, W.H. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA, 2002, 287, 356-359.
    • (2002) JAMA , vol.287 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3
  • 274
    • 43649091349 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among U.S. adolescents using the definition from the International Diabetes Federation
    • Ford, E.S.; Li, C.; Zhao, G.; Pearson, W.S.; Mokdah, A.H. Prevalence of the metabolic syndrome among U.S. adolescents using the definition from the International Diabetes Federation. Diabetes Care, 2008, 31, 587-589.
    • (2008) Diabetes Care , vol.31 , pp. 587-589
    • Ford, E.S.1    Li, C.2    Zhao, G.3    Pearson, W.S.4    Mokdah, A.H.5
  • 275
    • 60549107906 scopus 로고    scopus 로고
    • Metabolic syndrome clusters and the risk of incident stroke. The Atherosclerosis risk in communities (ARIC) study
    • Rodriguez-Colon, S.M.; Mo, J.; Duan, Y.; Liu, J.; Caulfield, J.E.; Jin, X.; Liao, D. Metabolic syndrome clusters and the risk of incident stroke. The Atherosclerosis risk in communities (ARIC) study. Stroke, 2009, 40, 200-205.
    • (2009) Stroke , vol.40 , pp. 200-205
    • Rodriguez-Colon, S.M.1    Mo, J.2    Duan, Y.3    Liu, J.4    Caulfield, J.E.5    Jin, X.6    Liao, D.7
  • 276
    • 67349091737 scopus 로고    scopus 로고
    • Oxidative stress and metabolic syndrome
    • Roberts, K.C.; Sindhu, K.K. Oxidative stress and metabolic syndrome. Life Sci., 2009, 84, 705-712.
    • (2009) Life Sci , vol.84 , pp. 705-712
    • Roberts, K.C.1    Sindhu, K.K.2
  • 277
    • 34147119059 scopus 로고    scopus 로고
    • Metabolic Syndrome and cognitive decline
    • Yaffe, K. Metabolic Syndrome and cognitive decline. Curr. Alzheimer Res., 2007, 4, 123-126.
    • (2007) Curr. Alzheimer Res , vol.4 , pp. 123-126
    • Yaffe, K.1
  • 278
  • 282
    • 64749095070 scopus 로고    scopus 로고
    • Effects of fenofibrate treatment on cardiovascular disease risk in 9,795 individuals with type 2 diabetes and various components of the metabolic syndrome
    • Scott, R.; O'Brien, R.; Fulcher, G.; Pardy, C.; D'Emden, M.; Tse, D.; Taskinen, M-R.; Enholm, C.; Keeck, A. Effects of fenofibrate treatment on cardiovascular disease risk in 9,795 individuals with type 2 diabetes and various components of the metabolic syndrome. Diabetes Care, 2009, 32, 493-498.
    • (2009) Diabetes Care , vol.32 , pp. 493-498
    • Scott, R.1    O'Brien, R.2    Fulcher, G.3    Pardy, C.4    D'Emden, M.5    Tse, D.6    Taskinen, M.-R.7    Enholm, C.8    Keeck, A.9
  • 283
    • 4544333229 scopus 로고    scopus 로고
    • Renin-angiotensin system and angiotensin receptor blockers in the metabolic syndrome
    • Prasad, A.; Quyyumi, A.A. Renin-angiotensin system and angiotensin receptor blockers in the metabolic syndrome. Circulation, 2004, 110, 1507-1512.
    • (2004) Circulation , vol.110 , pp. 1507-1512
    • Prasad, A.1    Quyyumi, A.A.2
  • 284
    • 70249088004 scopus 로고    scopus 로고
    • Effects of angiotensin II receptor blockers on dementia
    • Mogi, M.; Horiuchi, M. Effects of angiotensin II receptor blockers on dementia. Hypertens. Res., 2009, 32, 738-740.
    • (2009) Hypertens. Res , vol.32 , pp. 738-740
    • Mogi, M.1    Horiuchi, M.2
  • 285
    • 36249007030 scopus 로고    scopus 로고
    • Inhibition of cognitive decline in mice fed a high-salt and cholesterol diet by the angiotensin receptor blocker, olmesartan
    • Mogi, M.; Tsukuda, K.; Li, J-M.; Iwanami, J.; Min, L-J.; Sakata, A.; Fujita, T.; Iwai, M.; Horiuchi, M. Inhibition of cognitive decline in mice fed a high-salt and cholesterol diet by the angiotensin receptor blocker, olmesartan. Neuropharmacology, 2007, 53, 899-905.
    • (2007) Neuropharmacology , vol.53 , pp. 899-905
    • Mogi, M.1    Tsukuda, K.2    Li, J.-M.3    Iwanami, J.4    Min, L.-J.5    Sakata, A.6    Fujita, T.7    Iwai, M.8    Horiuchi, M.9
  • 286
    • 44249110198 scopus 로고    scopus 로고
    • Comparison of vasculoprotective effects of benidepine and losartan in a rat model of metabolic syndrome
    • Matsuzaki, G.; Ishizaka, N.; Furuta, K.; Hongo, M.; Saito, K.; Sakurai, R.; Koike, K.; Nagai, R. Comparison of vasculoprotective effects of benidepine and losartan in a rat model of metabolic syndrome. Eur. J. Pharmacol., 2008, 587, 237-242.
    • (2008) Eur. J. Pharmacol , vol.587 , pp. 237-242
    • Matsuzaki, G.1    Ishizaka, N.2    Furuta, K.3    Hongo, M.4    Saito, K.5    Sakurai, R.6    Koike, K.7    Nagai, R.8
  • 288
    • 73649103154 scopus 로고    scopus 로고
    • Long-term treatment with an angiotensin II receptor blocker decreases adipocyte size and improved insulin signaling in obese Zucker rats
    • Muñoz, M.C.; Giani, J.F.; Dominici, F.P.; Turyn, D.; Tobbli, J.E. Long-term treatment with an angiotensin II receptor blocker decreases adipocyte size and improved insulin signaling in obese Zucker rats. J. Hypertens., 2009, 27, 2409-2420.
    • (2009) J. Hypertens , vol.27 , pp. 2409-2420
    • Muñoz, M.C.1    Giani, J.F.2    Dominici, F.P.3    Turyn, D.4    Tobbli, J.E.5
  • 289
    • 2442566380 scopus 로고    scopus 로고
    • An active and socially integrated lifestyle in late life might protect against dementia
    • Fratiglioni, L.; Paillard-Borg, S.; Winblad, B. An active and socially integrated lifestyle in late life might protect against dementia. Lancet Neurol., 2004, 3, 343-353.
    • (2004) Lancet Neurol , vol.3 , pp. 343-353
    • Fratiglioni, L.1    Paillard-Borg, S.2    Winblad, B.3
  • 290
    • 34147145887 scopus 로고    scopus 로고
    • Cardiovascular risk factors and cognitive function
    • Grodstein, F. Cardiovascular risk factors and cognitive function. Alzheimer Dement., 2007, 3, S16-S22.
    • (2007) Alzheimer Dement , vol.3
    • Grodstein, F.1
  • 291
    • 67651094063 scopus 로고    scopus 로고
    • Current concepts in vascular cognitive impairment and pharmacotherapy implications
    • Rojas-Fernandez, C.H.; Moorhouse, P. Current concepts in vascular cognitive impairment and pharmacotherapy implications. Ann. Pharmacother., 2009, 43, 1310-1323.
    • (2009) Ann. Pharmacother , vol.43 , pp. 1310-1323
    • Rojas-Fernandez, C.H.1    Moorhouse, P.2
  • 293
    • 36448978905 scopus 로고    scopus 로고
    • Vascular disease: The tsunami of health care
    • Hakim, A.M. Vascular disease: the tsunami of health care. Stroke, 2007, 38, 3296-3301.
    • (2007) Stroke , vol.38 , pp. 3296-3301
    • Hakim, A.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.