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Volumn 46, Issue 3, 2011, Pages 901-906

Synthesis and evaluation of aroylthiourea derivatives of 4-β-amino-4'-O-demethyl-4-desoxypodophyllotoxin as novel topoisomerase II inhibitors

(6) Zhao, Yu a Ge, Cun Wang a Wu, Zhong Hua a Wang, Cheng Niu a Fang, Jing Huai a Zhu, Li a

a NANTONG UNIVERSITY (China)

Author keywords

4 Amino 4 O demethyl 4 desoxypodophyllotoxin; Anticancer agents; Aroylthiourea; Topoisomerase II

Indexed keywords

4 BETA (3 ALPHA NAPHTHOYLTHIOUREIDO) 4 O DEMETHYL 4 DESOXYPODOPHYLLOTOXIN; 4 BETA (3 BENZOYLTHIOUREIDO) 4 O DEMETHYL 4 DESOXYPODOPHYLLOTOXIN; 4 BETA (3 THIENYLTHIOUREIDO) 4 O DEMETHYL 4 DESOXYPODOPHYLLOTOXIN; 4 BETA [3 (2 IODOBENZOYL)THIOUREIDO] 4 O DEMETHYL 4 DESOXYPODOPHYLLOTOXIN; 4 BETA AMINO 4 O DEMETHYL 4 DESOXY PODOPHYLLOTOXIN; ANTINEOPLASTIC AGENT; GYRASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL STRAIN HCT116; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; FLOW CYTOMETRY;

ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL PROLIFERATION; DNA TOPOISOMERASES, TYPE II; HCT116 CELLS; HEP G2 CELLS; HUMANS; NEOPLASMS; PODOPHYLLOTOXIN; PODOPHYLLUM; THIOUREA; TOPOISOMERASE II INHIBITORS;

EID: 79951676938 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2011.01.001 Document Type: Article

Times cited : (32)

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