Left-ventricular remodeling after myocardial infarction is associated with a cardiomyocyte-specific hypothyroid condition

Endocrinology

Volumn 152, Issue 2, 2011, Pages 669-679

  Pol, Christine J ^a   Muller, Alice ^a   Zuidwijk, Marian J ^a   Van Deel, Elza D ^b   Kaptein, Ellen ^b   Saba, Alessandro ^c   Marchini, Maja ^c   Zucchi, Riccardo ^c   Visser, Theo J ^b   Paulus, Walter J ^a   Duncker, Dirk J ^b   Simonides, Warner S ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LUCIFERASE; MESSENGER RNA; OXIDOREDUCTASE; THYROID HORMONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DILATION AND EVACUATION; ENZYME ACTIVITY; FIBROSING ALVEOLITIS; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEART INFARCTION; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART VENTRICLE REMODELING; HUMAN; HYPERTROPHY; HYPOTHYROIDISM; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; THYROID HORMONE BLOOD LEVEL;

ANIMALS; BLOTTING, WESTERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HYPOTHYROIDISM; IODIDE PEROXIDASE; MALE; MICE; MICE, INBRED C57BL; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; RANDOM ALLOCATION; THYROID HORMONES; VENTRICULAR REMODELING;

EID: 79951666820     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2010-0431     Document Type: Article

References (53)

1. Sutton MG, Sharpe N 2000 Left ventricular remodeling after myocardial infarction. Pathophysiology and therapy. Circulation 101:2981-2988
2. Braunwald E, Bristow MR 2000 Congestive heart failure: fifty years of progress. Circulation 102:14-23
3. Ritter O, Neyses L 2003 The molecular basis of myocardial hypertrophy and heart failure. Trends Mol Med 9:313-321 (Pubitemid 37039966)
4. Danzi S, Klein I 2002 Thyroid hormone-regulated cardiac gene expression and cardiovascular disease. Thyroid 12:467-472 (Pubitemid 34721542)
5. Ojamaa K, Kenessey A, Shenoy R, Klein I 2000 Thyroid hormone metabolism and cardiac gene expression after acute myocardial infarction in the rat. Am J Physiol-Endocr M 279:E1319-E1324
6. Bristow MR, Minobe WA, Raynolds MV, Port JD, Rasmussen R, Ray PE, Feldman AM 1993 Reduced β1 receptor messenger RNA abundance in the failing human heart. J Clin Invest 92:2737-2745
7. Lowes BD, Minobe W, Abraham WT, Rizeq MN, Bohlmeyer TJ, Quaife RA, Roden RL, Dutcher DL, Robertson AD, Voelkel NF, Badesch DB, Groves BM, Gilbert EM, Bristow MR 1997 Changes in gene expression in the intact human heart-downregulation of α-myosin heavy chain in hypertrophied, failing ventricular myocardium. J Clin Invest 100:2315-2324 (Pubitemid 27500155)
8. Trivieri MG, Oudit GY, Sah R, Kerfant BG, Sun H, Gramolini AO, Pan Y, Wickenden AD, Croteau W, Morreale de Escobar G, Pekhletski R, St Germain D, MacLennan DH, Backx PH 2006 Cardiac- specific elevations in thyroid hormone enhance contractility and prevent pressure overload-induced cardiac dysfunction. Proc Natl Acad Sci USA 103:6043-6048
9. Pingitore A, Landi P, Taddei MC, Ripoli A, L'Abbate A, Iervasi G 2005 Triiodothyronine levels for risk stratification of patients with chronic heart failure. Am J Med 118:132-136 (Pubitemid 40202859)
10. Pantos C, Dritsas A, Mourouzis I, Dimopoulos A, Karatasakis G, Athanassopoulos G, Mavrogeni S, Manginas A, Cokkinos DV 2007 Thyroid hormone is a critical determinant of myocardial performance in patients with heart failure: potential therapeutic implications. Eur J Endocrinol 157:515-520 (Pubitemid 350018456)
11. Pantos C, Mourouzis I, Markakis K, Tsagoulis N, Panagiotou M, Cokkinos DV 2008 Long-term thyroid hormone administration reshapes left ventricular chamber and improves cardiac function after myocardial infarction in rats. Basic Res Cardiol 103:308-318
12. Henderson KK, Danzi S, Paul JT, Leya G, Klein I, Samarel AM 2009 Physiological replacement of T-3 improves left ventricular function in an animal model of myocardial infarction-induced congestive heart failure. Circ-Heart Fail 2:243-252
13. Belke DD, Gloss B, Swanson EA, Dillmann WH 2007 Adeno-associated virus-mediated expression of thyroid-hormone-receptor isoforms-α 1 and -β 1 improves contractile function in pressure overload-induced cardiac hypertrophy. Endocrinology 148:2870-2877 (Pubitemid 46984823)
14. Pantos C, Mourouzis I, Xinaris C, Kokkinos AD, Markakis K, Dimopoulos A, Panagiotou M, Saranteas T, Kostopanagiotou G, Cokkinos DV 2007 Time-dependent changes in the expression of thyroid hormone receptor α 1 in the myocardium after acute myocardial infarction: possible implications in cardiac remodellin. Eur J Endocrinol 156:415-424 (Pubitemid 46672641)
15. Pantos C, Mourouzis I, Saranteas T, Paizis I, Xinaris C, Malliopoulou V, Cokkinos DV 2005 Thyroid hormone receptors α 1 and β 1 are downregulated in the post-infarcted rat heart: consequences on the response to ischaemia-reperfusion. Basic Res Cardiol 100:422-432 (Pubitemid 41300497)
16. Kinugawa K, Yonekura K, Ribeiro RC, Eto Y, Aoyagi T, Baxter JD, Camacho SA, Bristow MR, Long CS, Simpson PC 2001 Regulation of thyroid hormone receptor isoforms in physiological and pathological cardiac hypertrophy. Circ Res 89:591-598 (Pubitemid 32924213)
17. Wassen FW, Schiel AE, Kuiper GG, Kaptein E, Bakker O, Visser TJ, Simonides WS 2002 Induction of thyroid hormone-degrading deiodinase in cardiac hypertrophy and failure. Endocrinology 143:2812-2815 (Pubitemid 34701346)
18. Olivares EL, Marassi MP, Fortunato RS, da Silva AC, Costa-e-Sousa RH, Araújo IG, Mattos EC, Masuda MO, Mulcahey MA, Huang SA, Bianco AC, Carvalho DP 2007 Thyroid function disturbance and type 3 iodothyronine deiodinase induction after myocardial infarction in rats. A time course study. Endocrinology 148:4786-4792 (Pubitemid 47481559)
19. Gereben B, Zavacki AM, Ribich S, Kim BW, Huang SA, Simonides WS, Zeöld A, Bianco AC 2008 Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling. Endocr Rev 29:898-938
20. Hernandez A 2005 Structure and function of the type 3 deiodinase gene. Thyroid 15:865-874 (Pubitemid 41339265)
21. Simonides WS, Mulcahey MA, Redout EM, Muller A, Zuidwijk MJ, Visser TJ, Wassen FW, Crescenzi A, da-Silva WS, Harney J, Engel FB, Obregon MJ, Larsen PR, Bianco AC, Huang SA 2008 Hypoxiainducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats. J Clin Invest 118:975-983
22. van den Bos EJ, Mees BME, de Waard MC, de Crom R, Duncker DJ 2005 A novel model of cryoinjury-induced myocardial infarction in the mouse: a comparison with coronary artery ligation. Am J Physiol-Heart C 289:H1291-H1300 (Pubitemid 41208975)
23. de Waard MC, van der Velden J, Bito V, Ozdemir S, Biesmans L, Boontje NM, Dekkers DH, Schoonderwoerd K, Schuurbiers HC, de Crom R, Stienen GJ, Sipido KR, Lamers JM, Duncker DJ 2007 Early exercise training normalizes myofilament function and attenuates left ventricular pump dysfunction in mice with a large myocardial infarction. Circ Res 100:1079-1088 (Pubitemid 46598933)
24. Kuiper GG, Klootwijk W, Visser TJ 2003 Substitution of cysteine for selenocysteine in the catalytic center of type III iodothyronine deiodinase reduces catalytic efficiency and alters substrate preference. Endocrinology 144:2505-2513 (Pubitemid 36629903)
25. Friedrichsen S, Christ S, Heuer H, Schäfer MK, Mansouri A, Bauer K, Visser TJ 2003 Regulation of iodothyronine deiodinases in the Pax8(-/-) mouse model of congenital hypothyroidism. Endocrinology 144:777-784 (Pubitemid 36262844)
26. Saba A, Chiellini G, Frascarelli S, Marchini M, Ghelardoni S, Raffaelli A, Tonacchera M, Vitti P, Scanlan TS, Zucchi R 2010 Tissue distribution and cardiac metabolism of 3-iodothyronamine. Endocrinology 151:5063-5073
27. Huang SA, Fish SA, Dorfman DM, Salvatore D, Kozakewich HP, Mandel SJ, Larsen PR 2002 A 21-year-oldwomanwith consumptive hypothyroidism due to a vascular tumor expressing type 3 iodothyronine deiodinase. J Clin Endocr Metab 87:4457-4461 (Pubitemid 35247024)
28. Des Tombe AL, Beek-Harmsen BJ, Lee-De Groot MBE, Van Der Laarse WJ 2002 Calibrated histochemistry applied to oxygen supply and demand in hypertrophied rat myocardium. Microsc Res Techniq 58:412-420 (Pubitemid 34983280)
29. Whittaker P, Kloner RA, Boughner DR, Pickering JG 1994 Quantitative assessment of myocardial collagen with picrosirius red staining and circularly polarized light. Basic Res Cardiol 89:397-410
30. Boelen A, Kwakkel J, Alkemade A, Renckens R, Kaptein E, Kuiper G, Wiersinga WM, Visser TJ 2005 Induction of type 3 deiodinase activity in inflammatory cells of mice with chronic local inflammation. Endocrinology 146:5128-5134 (Pubitemid 41653026)
31. Boelen A, Boorsma J, Kwakkel J, Wieland CW, Renckens R, Visser TJ, Fliers E, Wiersinga WM 2008 Type 3 deiodinase is highly expressed in infiltrating neutrophilic granulocytes in response to acute bacterial infection. Thyroid 18:1095-1103
32. Boelen A, Mikita J, Boiziau C, Chassande O, Fliers E, Petry KG 2009 Type 3 deiodinase expression in inflammatory spinal cord lesions in rat experimental autoimmune encephalomyelitis. Thyroid 19:1401-1406
33. Huang SA, Dorfman DM, Genest DR, Salvatore D, Larsen PR 2003 Type 3 iodothyronine deiodinase is highly expressed in the human uteroplacental unit and in fetal epithelium. J Clin Endocr Metab 88:1384-1388 (Pubitemid 36337804)
34. Liu YY, Brent GA 2008 Stealth sequences in reporter gene vectors confound studies of T3-regulated negative gene expression. Thyroid 18:593-595 (Pubitemid 351918462)
35. Locher MR, Razumova MV, Stelzer JE, Norman HS, Patel JR, Moss RL 2009 Determination of rate constants for turnover of myosin isoforms in rat myocardium: implications for in vivo contractile kinetics. Am J Physiol-Heart C 297:H247-H256
36. Korte FS, Herron TJ, Rovetto MJ, McDonald KS 2005 Power output is linearly related to MyHC content in rat skinned myocytes and isolated working hearts. Am J Physiol-Heart C 289:H801-H812 (Pubitemid 41129398)
37. Yang YN, Ma YT, Han W, Li J, Xiang Y, Liu F, Ma X, Zhang J, Fu ZY, Su YD, Du XJ, Gao XM 2008 Age-related differences in postinfarct left ventricular rupture and remodeling. Am J Physiol-Heart C 294:H1815-H1822 (Pubitemid 351490611)
38. Kido M, Du L, Sullivan CC, Li X, Deutsch R, Jamieson SW, Thistlethwaite PA 2005 Hypoxia-inducible factor 1-α reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse. J Am Coll Cardiol 46:2116-2124 (Pubitemid 41713601)
39. Hayashidani S, Tsutsui H, Ikeuchi M, Shiomi T, Matsusaka H, Kubota T, Imanaka-Yoshida K, Itoh T, Takeshita A 2003 Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction. Am J Physio-Heart C 285:H1229-H1235 (Pubitemid 37048181)
40. Jones SP, Greer JJ, Ware PD, Yang J, Walsh K, Lefer DJ 2005 Deficiency of iNOS does not attenuate severe congestive heart failure in mice. Am J Physiol Heart Circ Physiol 288:H365-H370 (Pubitemid 40023868)
41. Dawson D, Lygate CA, Zhang MH, Hulbert K, Neubauer S, Casadei B 2005 nNOS gene deletion exacerbates pathological left ventricular remodeling and functional deterioration after myocardial infarction. Circulation 112:3729-3737 (Pubitemid 43739513)
42. Dillmann W 2009 Cardiac hypertrophy and thyroid hormone signaling. Heart Fail Rev 12:125-132
43. Li GH, Shi Y, Chen Y, Sun M, Sader S, Maekawa Y, Arab S, Dawood F, Chen M, De Couto G, Liu Y, Fukuoka M, Yang S, Da Shi M, Kirshenbaum LA, McCulloch CA, Liu P 2009 Gelsolin regulates cardiac remodeling after myocardial infarction through DNase Imediated apoptosis. Circ Res 104:896-904
44. Sano M, Minamino T, Toko H, Miyauchi H, Orimo M, Qin Y, Akazawa H, Tateno K, Kayama Y, Harada M, Shimizu I, Asahara T, Hamada H, Tomita S, Molkentin JD, Zou Y, Komuro I 2007 p53-Induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload. Nature 446:444-448 (Pubitemid 46474597)
45. Huang SA, Mulcahey MA, Crescenzi A, Chung M, Kim BW, Barnes C, Kuijt W, Turano H, Harney J, Larsen PR 2005 Transforming growth factor-β promotes inactivation of extracellular thyroid hormones via transcriptional stimulation of type 3 iodothyronine deiodinase. Mol Endocrinol 19:3126-3136 (Pubitemid 41697726)
46. Rosenkranz S 2004 TGF-β(1) and angiotensin networking in cardiac remodeling. Cardiovas Res 63:423-432
47. Lim H, Zhu YZ 2006 Role of transforming growth factor-β in the progression of heart failure. Cell Mol Life Sci 63:2584-2596 (Pubitemid 44800713)
48. Dentice M, Luongo C, Huang S, Ambrosio R, Elefante A, Mirebeau- Prunier D, Zavacki AM, Fenzi G, Grachtchouk M, Hutchin M, Dlugosz AA, Bianco AC, Missero C, Larsen PR, Salvatore D 2007 Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes. Proc Natl Acad Sci USA 104:14466-14471 (Pubitemid 350003284)
49. Kusano KF, Pola R, Murayama T, Curry C, Kawamoto A, Iwakura A, Shintani S, Ii M, Asai J, Tkebuchava T, Thorne T, Takenaka H, Aikawa R, Goukassian D, von Samson P, Hamada H, Yoon YS, Silver M, Eaton E, Ma H, Heyd L, Kearney M, Munger W, Porter JA, Kishore R, Losordo DW 2005 Sonic hedgehog myocardial gene therapy: tissue repair through transient reconstitution of embryonic signaling. Nat Med 11:1197-1204 (Pubitemid 43093667)
50. Yu CM, Lai KW, Chen YX, Huang XR, Lan HY 2003 Expression of macrophage migration inhibitory factor in acute ischemic myocardial injury. J Histochem Cytochem 51:625-631 (Pubitemid 36520618)
51. van Rooij E, Doevendans PA, Crijns HJ, Heeneman S, Lips DJ, van Bilsen M, Williams RS, Olson EN, Bassel-Duby R, Rothermel BA, De Windt LJ 2004 MCIP1 overexpression suppresses left ventricular remodeling and sustains cardiac function after myocardial infarction. Circ Res 94:E18-E26
52. Tsoporis JN, Marks A, Haddad A, Dawood F, Liu PP, Parker TG 2005 S100B expression modulates left ventricular remodeling after myocardial infarction in mice. Circulation 111:598-606 (Pubitemid 40216487)
53. Pandya K, Kim HS, Smithies O 2006 Fibrosis, not cell size, delineates β-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo. Proc Natl Acad Sci USA 103:16864-16869 (Pubitemid 44737344)