Thyroid hormone is a critical determinant of myocardial performance in patients with heart failure: Potential therapeutic implications

European Journal of Endocrinology

Volumn 157, Issue 4, 2007, Pages 515-520

  Pantos, Constantinos ^a   Dritsas, Athanasios ^b   Mourouzis, Iordanis ^a   Dimopoulos, Antonios ^a   Karatasakis, Georgios ^a   Athanassopoulos, Georgios ^b   Mavrogeni, Sofia ^b   Manginas, Athanasios ^b   Cokkinos, Dennis V ^b  

^a UNIVERSITY OF ATHENS   (Greece)

^b ONASSIS CARDIAC SURGERY CENTER   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; LIOTHYRONINE; OXYGEN; THYROID HORMONE; THYROTROPIN; THYROXINE;

ADULT; ARTICLE; CARDIOPULMONARY EXERCISE TEST; CLINICAL ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ECHOCARDIOGRAPHY; FEMALE; FUNCTIONAL STATUS; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART PERFORMANCE; HUMAN; LIOTHYRONINE BLOOD LEVEL; MALE; MULTIVARIATE ANALYSIS; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PREDICTION; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL;

ADULT; AMIODARONE; ANTI-ARRHYTHMIA AGENTS; CARDIOMYOPATHY, DILATED; EXERCISE TEST; FEMALE; FORCED EXPIRATORY VOLUME; HEART; HEART FAILURE; HUMANS; MALE; MIDDLE AGED; THYROID HORMONES; THYROTROPIN; VENTRICULAR FUNCTION, LEFT;

EID: 35549012856     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/EJE-07-0318     Document Type: Article

References (20)

1. Klein I & Ojamaa K. Thyroid hormone and the cardiovascular system. New England Journal of Medicine 2001 344 501-509.
2. Pantos C, Malliopoulou V, Varonos DD & Cokkinos DV. Thyroid hormone and phenotypes of cardioprotection. Basic Research in Cardiology 2004 99 101-120.
3. Ascheim DD & Hryniewicz K. Thyroid hormone metabolism in patients with congestive heart failure: the low triiodothyronine state. Thyroid 2002 12 511-515.
4. Manowitz NR, Mayor GH, Klepper MJ & DeGroot LJ. Subclinical hypothyroidism and euthyroid sick syndrome in patients with moderate-to-severe congestive heart failure. American Journal of Therapeutics 1996 3 797-801.
5. Pingitore A, Landi P, Taddei MC, Ripoli A, L'Abbate A & Iervasi G. Triiodothyronine levels for risk stratification of patients with chronic heart failure. American Journal of Medicine 2005 118 132-136.
6. Schmidt-Ott UM & Ascheim DD. Thyroid hormone and heart failure. Current Heart Failure Reports 2006 3 114-119.
7. Belke DD, Gloss B, Swanson EA & Dillmann WH. AAV-mediated expression of thyroid hormone receptor isoforms α1 and β1 improves contractile function in pressure overload-induced cardiac hypertrophy. Endocrinology 2007 148 2870-2877.
8. Kinugawa K, Yonekura K, Ribeiro RC, Eto Y, Aoyagi T, Baxter JD, Camacho SA, Bristow MR, Long CS & Simpson PC. Regulation of thyroid hormone receptor isoforms in physiological and pathological cardiac hypertrophy. Circulation Research 2001 89 591-598.
9. Pantos C, Mourouzis I, Saranteas T, Paizis I, Xinaris C, Malliopoulou V & Cokkinos DV. Thyroid hormone receptors α1 and β1 are downregulated in the post-infarcted rat heart: consequences on the response to ischaemia-reperfusion. Basic Research in Cardiology 2005 100 422-432.
10. Pantos C, Mourouzis I, Xinaris C, Kokkinos AD, Markakis K, Dimopoulos A, Panagiotou M, Saranteas T, Kostopanagiotou G & Cokkinos DV. Time-dependent changes in the expression of thyroid hormone receptor α1 in the myocardium after acute myocardial infarction: possible implications in cardiac remodelling. European Journal of Endocrinology 2007 156 415-424.
11. Riley M, Northridge DB, Henderson E, Stanford CF, Nicholls DP & Dargie HJ. The use of an exponential protocol for bicycle and treadmill exercise testing in patients with chronic cardiac failure. European Heart Journal 1992 13 1363-1367.
12. Amico JA, Richardson V, Alpert B & Klein I. Clinical and chemical assessment of thyroid function during therapy with amiodarone. Archives of Internal Medicine 1984 144 487-490.
13. d'Amati G, di Gioia CR, Mentuccia D, Pistilli D, Proietti-Pannunzi L, Miraldi F, Gallo P & Celi FS. Increased expression of thyroid hormone receptor isoforms in end-stage human congestive heart failure. Journal of Clinical Endocrinology and Metabolism 2001 86 2080-2084.
14. Pingitore A, Iervasi G, Barison A, Prontcra C, Pratali L, Emdin M, Giannessi D & Neglia D. Early activation of an altered thyroid hormone profile in asymptornatic or mildly symptomatic idiopathic left ventricular dysfunction. Journal of Cardiac Failure 2006 12 520-526.
15. Luboshitzky R, Aviv A, Herer P & Lavic L. Risk factors for cardiovascular disease in women with subclinical hypothyroidism. Thyroid 2002 12 421-425.
16. Biondi B & Klein I. Hypothyroidism as a risk factor for cardiovascular disease. Endocrine 2004 24 1-14.
17. Weber KT, Kinasewitz GT, Janicki JS & Fishman AP. Oxygen utilization and ventilation during exercise in patients with chronic cardiac failure. Circulation 1982 65 1213-1223.
18. Cohn JN, Johnson GR, Shabetai R, Loeb H, Tristani F, Rector T, Smith R & Fletcher R. Ejection fraction, peak exercise oxygen consumption, cardiothoracic ratio, ventricular arrhythmias, and plasma norepinephrine as determinants of prognosis in heart failure. The V-HeFT VA Cooperative Studies Group. Circulation 1993 87 VI5-VI16.
19. O'neill JO, Young JB, Pothier CE & Lauer MS. Peak oxygen consumption as a predictor of death in patients with heart failure receiving beta-blockers. Circulation 2005 111 2313-2318.
20. Mancini DM, Eisen H, Kussmaul W, Mull R, Edmunds LH & Wilson JR. Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure. Circulation 1991 83 778-786.