Adeno-associated virus-mediated expression of thyroid hormone receptor isoforms-α1 and -β1 improves contractile function in pressure overload-induced cardiac hypertrophy

Endocrinology

Volumn 148, Issue 6, 2007, Pages 2870-2877

  Belke, Darrell D ^a   Gloss, Bernd ^a,b   Swanson, Eric A ^a   Dillmann, Wolfgang H ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); BETA GALACTOSIDASE; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR ALPHA 1; THYROID HORMONE RECEPTOR BETA 1; UNCLASSIFIED DRUG;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; AORTA CONSTRICTION; ARTICLE; CONTROL GROUP; CONTROLLED STUDY; GENE EXPRESSION; GENE THERAPY; HEART FUNCTION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANIMALS; CARDIOMYOPATHY, HYPERTROPHIC; CELLS, CULTURED; DEPENDOVIRUS; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; MALE; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RNA, MESSENGER; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; THYROID HORMONE RECEPTORS ALPHA; THYROID HORMONE RECEPTORS BETA; VENTRICULAR PRESSURE;

EID: 34250832312     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-0009     Document Type: Article

References (36)

1. Gerdes AM 2002 Cardiac myocyte remodeling in hypertrophy and progression to failure. J Card Fail 8:S264-S268
2. Ito K, Yan X, Feng X, Manning WJ, Dillmann WH, Lorell BH 2001 Transgenic expression of sarcoplasmic reticulum Ca(2+) ATPase modifies the transition from hypertrophy to early heart failure. Circ Res 89:422-429
3. Izumo S, Lompre AM, Matsuoka R, Koren G, Schwartz K, Nadal-Ginard B, Mahdavi V 1987 Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. Interaction between hemodynamic and thyroid hormone-induced signals. J Clin Invest 79:970-977
4. Ito K, Yan X, Tajima M, Su Z, Barry WH, Lorell BH 2000 Contractile reserve and intracellular calcium regulation in mouse myocytes from normal and hypertrophied failing hearts. Circ Res 87:588-595
5. Vigouroux E 1976 Dynamic study of post-natal thyroid function in the rat. Acta Endocrinol (Copenh) 83:752-762
6. Barger PM, Kelly DP 1999 Fatty acid utilization in the hypertrophied and failing heart: molecular regulatory mechanisms. Am J Med Sci 318:36-42
7. Kolar F, Seppet EK, Vetter R, Prochazaka J, Grunermel J, Zimler K, Ostadal B1992 Thyroid control of contractile function and calcium handling in neonatal rat heart. Pflugers Arch 421:26-31
8. Canavan JP, Holt J, Goldspink DF 1994 The influence of thyroid hormones on the growth of the atria and ventricles of the heart in immature rats. J Endocrinol 142:171-179
9. Kuzman JA, Thomas TA, Vogelsang KA, Said S, Anderson BE, Gerdes AM 2005 Effects of induced hyperthyroidism in normal and cardiomyopathic hamsters. J Appl Physiol 99:1428-1433
10. Kinugawa K, Yonekura K, Ribeiro RC, Eto Y, Aoyagi T, Baxter JD, Camacho SA, Bristow MR, Long CS, Simpson PC 2001 Regulation of thyroid hormone receptor isoforms in physiological and pathological cardiac hypertrophy. Circ Res 89:591-598
11. Kinugawa K, Minobe WA, Wood WM, Ridgway EC, Baxter JD, Ribeiro RC, Tawadrous MF, Lowes BA, Long CS, Bristow MR 2001 Signaling pathways responsible for fetal gene induction in the failing human heart: evidence for altered thyroid hormone receptor gene expression. Circulation 103:1089-1094
12. Sylven C, Jansson E, Sotonyi P, Waagstein F, Barkhem T, Bronnegard M 1996 Cardiac nuclear hormone receptor mRNA in heart failure in man. Life Sci 59:1917-1922
13. Thomas TA, Kuzman JA, Anderson BE, Andersen SM, Schlenker EH, Holder MS, Gerdes AM 2005 Thyroid hormones induce unique and potentially beneficial changes in cardiac myocyte shape in hypertensive rats near heart failure. Am J Physiol Heart Circ Physiol 288:H2118-H2122
14. Chang KC, Figueredo VM, Schreur JH, Kariya K, Weiner MW, Simpson PC, Camacho SA 1997 Thyroid hormone improves function and Ca2+ handling in pressure overload hypertrophy. Association with increased sarcoplasmic reticulum Ca2+-ATPase and α-myosin heavy chain in rat hearts. J Clin Invest 100:1742-1749
15. Samulski RJ, Chang LS, Shenk T 1989 Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression. J Virol 63:3822-3828
16. Grimm D, Kern A, Rittner K, Kleinschmidt JA 1998 Novel tools for production and purification of recombinant adeno-associated virus vectors. Hum Gene Ther 9:2745-2760
17. Meyer M, Belke DD, Trost SU, Swanson E, Dieterle T, Scott B, Cary SP, Ho P, Bluhm WF, McDonough PM, Silverman GJ, Dillmann WH 2004 A recombinant antibody increases cardiac contractility by mimicking phospholamban phosphorylation FASEB J 18:1312-1314
18. Trost SU, Belke DD, Bluhm WF, Meyer M, Swanson E, Dillmann WH 2002 Overexpression of the sarcoplasmic reticulum Ca(2+)-ATPase improves myocardial contractility in diabetic cardiomyopathy. Diabetes 51:1166-1171
19. Kameyama T, Chen Z, Bell SP, Fabian J, LeWinter MM 1998 Mechanoenergetic studies in isolated mouse hearts. Am J Physiol 274:H366-H374
20. Belke DD, Betuing S, Tuttle MJ, Pham M, Yong ME, Graveleau C, Zhang D, Litwin SE, Taegtmeyer H, Severson DL, Kahn CR, Abel ED 2002 Central role of insulin signaling in the coordinate regulation of size, metabolism and contractile protein isoform expression in the mammalian heart. J Clin Invest 109:629-639
21. Suarez J, Belke DD, Gloss B, Dieterle T, McDonough PM, Brunton LL, Dillmann WH 2004 In vivo adenoviral transfer of sorcin reverses the contractile abnormalities of diabetic cardiomyopathy. Am J Physiol Heart Circ Physiol 286:H68-H75
22. Gloss B, Trost S, Bluhm W, Swanson E, Clark R, Winkfein R, Janzen K, Giles W, Chassande O, Samarut J, Dillmann W 2001 Cardiac ion channel expression and contractile function in mice with deletion of thyroid hormone receptor α or β. Endocrinology 142:544-550
23. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
24. Gloss B, Sayen MR, Trost SU, Bluhm WF, Meyer M, Swanson EA, Usala SJ, Dillmann WH 1999 Altered cardiac phenotype in transgenic mice carrying the Δ337 threonine thyroid hormone receptor β mutant derived from the S family. Endocrinology 140:897-902
25. Pantos C, Mourouzis I, Saranteas T, Paizis I, Xinaris C, Malliopoulou V, Cokkinos DV 2005 Thyroid hormone receptors α1 and β1 are downregulated in the post-infarcted rat heart: consequences on the response to ischaemiareperfusion. Basic Res Cardiol 100:422-432
26. Pingitore A, Landi P, Taddei MC, Ripoli A, L'Abbate A, Iervasi G 2005 Triiodothyronine levels for risk stratification of patients with chronic heart failure. Am J Med 118:132-136
27. Belke DD, Gloss B, Hollander JM, Swanson EA, Duplain H, Dillmann WH 2006 In vivo gene delivery of HSP70i by adenovirus and adeno-associated virus preserves contractile function in mouse heart following ischemia-reperfusion. Am J Physiol Heart Circ Physiol 291:H2905-H2910
28. Danzi S, Dubon P, Klein I 2005 Effect of serum triiodothyronine on regulation of cardiac expression: role of histone acetylation. Am J Physiol Heart Circ Physiol 289:H1506-H1511
29. Dieterle T, Meyer M, Gu Y, Belke DD, Swanson E, Iwatate M, Hollander J, Peterson KL, Ross Jr J, Dillmann WH 2005 Gene transfer of a phospholambantargeted antibody improves calcium handling and cardiac function in heart failure. Cardiovasc Res 67:678-688
30. Suarez J, Gloss B, Belke DD, Hu Y, Scott B, Dieterle T, Kim YK, Valencik M, McDonnald JA, Dillmann WH 2004 Doxycycline inducible expression of SERCA2 improves calcium handling and reverts cardiac dysfunction in pressure overload-induced hypertrophy. Am J Physiol Heart Circ Physiol 287:H2164-H2172
31. Kinugawa K, Jeong MY, Bristow MR, Long CS 2005 Thyroid hormone induces cardiac myocyte hypertrophy in a thyroid hormone receptor α1 specific manner that requires TAK1 and p38 mitogen-activated protein kinase. Mol Endocrinol 19:1618-1628
32. Nag AC, Cheng M, Fischman DA, Zak R 1983 Long-term cell culture of adult mammalian cardiac myocytes: electron microscopic and immunofluorescent analysis of myofibrillar structure. J Mol Cell Cardiol 15:301-317
33. Weisser-Thomas J, Dieterich E, Janssen PM Schmidt-Schweda S, Maier LS, Sumbilla C, Pieske B 2005 Method-related effects of adenovirus-mediated LacZ and SERCA1 gene transfer on contractile behavior of cultured failing human cardiomyocytes. J Pharmacol Toxicol Methods 51:91-103
34. Khalife WI, Tang YD, Kuzman JA, Thomas TA, Anderson BE, Said S, Tille P, Schlenker EH, Gerdes AM 2005 Treatment of sub-clinical hypothyroidism reverses ischemia and prevents myocyte loss and progressive LV dysfunction in hamsters with dilated cardiomyopathy. Am J Physiol Heart Circ Physiol 289:H2409-H2415
35. Yen PM 2001 Physiological and molecular basis of thyroid hormone action. Physiol Rev 81:1097-1142
36. Oppenheimer JH, Schwartz HL, Koener D, Surks MI 1974 Limited binding capacity sites for L-triiodothyronine in rat liver nuclei. Nuclear-cytoplasmic interrelation, binding, constants, and cross-reactivity with L-thyroxine. J Clin Invest 53:768-777