Stealth sequences in reporter gene vectors confound studies of T3-regulated negative gene expression

Thyroid

Volumn 18, Issue 6, 2008, Pages 593-595

  Liu, Yan Yun ^a   Brent, Gregory A ^a  

^a VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIOTHYRONINE; LUCIFERASE; THYROID HORMONE RECEPTOR;

BINDING SITE; DNA SEQUENCE; EDITORIAL; GENE CONTROL; GENE EXPRESSION; GENE SEQUENCE; GENE VECTOR; GENETIC TRANSCRIPTION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BOUND IODINE; PROTEIN DNA BINDING; REPORTER GENE;

ANIMALS; BASE SEQUENCE; CACO-2 CELLS; CELL LINE; GENE EXPRESSION REGULATION; GENES, REPORTER; GENETIC VECTORS; HUMANS; LUCIFERASES; MICE; MICE, TRANSGENIC; PLASMIDS; PROMOTER REGIONS (GENETICS); RESPONSE ELEMENTS; TRANSFECTION; TRIIODOTHYRONINE;

EID: 46349092321     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/thy.2008.0138     Document Type: Editorial

References (11)

1. Chan IH, Borowsky AD, Privalsky ML 2008 A cautionary note as to the use of pBi-L and related luciferase/transgenic vectors in the study of thyroid endocrinology [letter]. Thyroid 18:665-666.
2. Tillman JB, Crone DE, Kim HS, Sprung CN, Spindler SR 1993 Promoter independent down-regulation of the firefly luciferase gene by T3 and T3 receptor in CV1 cells. Mol Cell Endocrinol 95:101-109.
3. Maia AL, Harney JW, Larsen PR 1996 Is there a negative TRE in the luciferase reporter cDNA? Thyroid 6:325-328.
4. Prathalingam SR, Howard A, Barley NF, Legon S, Walters JR 1998 Inhibition of luciferase expression from a commercial reporter vector by 1,25-dihydroxychole-calciferol. Anal Biochem 263:113-115.
5. Kogai T, Kanamoto Y, Brent GA 2003 The modified firely luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-transretinoic acid in MCF-7 breast cancer cells. Breast Cancer Res Treat 78:119-126.
6. Oetting A, Yen PM 2007 New insights into thyroid hormone action. Best Pract Res Clin Endocrinol Metab 21:193-208.
7. Brent GA, Williams GR, Harney JW, Forman BM, Samuels HH, Moore DD, Larsen PR 1991 Effects of varying the position of thyroid hormone response elements within the rat growth hormone promoter: implications for positive and negative regulation by 3,5,3′-triiodothyronine. Mol Endocrinol 5:542-548.
8. Shibusawa N, Hashimoto K, Nikrodhanond AA, Liberman MC, Applebury ML, Liao XH, Robbins JT, Refetoff S, Cohen RN, Wondisford FE 2003 Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo. J Clin Invest 112:588-597.
9. Kim SW, Ho SC, Hong SJ, Kim KM, Edward C, Christoffolete SM, Harney JW 2005 A novel mechanism of thyroid hormone-dependent negative regulation by thyroid hormone receptor, nuclear receptor corepressor (NCoR), and GAGA-binding factor on the rat CD44 promoter. J Biol Chem 280:14545-14555.
10. Drover VA, Wong NC, Agellon LB 2002 A distinct thyroid hormone response element mediates repression of the human cholesterol 7alpha-hydroxylase (CYP7A1) gene promoter. Mol Endocrinol 16:14-23.
11. Lopez G, Schaufele F, Webb P, Holloway JM, Baxter JD, Kushner PJ 1993 Positive and negative modulation of Jun action by thyroid hormone receptor at a unique AP1 site. Mol Cell Biol 13:3042-3049.