A ketogenic diet impairs energy and glucose homeostasis by the attenuation of hypothalamic leptin signaling and hepatic insulin signaling in a rat model of non-obese type 2 diabetes

Experimental Biology and Medicine

Volumn 236, Issue 2, 2011, Pages 194-204

  Park, Sunmin ^a   Kim, Da Sol ^a   Kang, Sunna ^a   Daily III, James W ^b  

^a Hoseo University   (South Korea)

^b Daily Manufacturing Inc   (United States)

Author keywords

hydroxybutyrate; AMPK; Insulin resistance; Insulin secretion; Insulin signaling; Leptin

Indexed keywords

3 HYDROXYBUTYRIC ACID; CYCLIC AMP; GLUCAGON; HYPERGLYCEMIC AGENT; INSULIN; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALORIC INTAKE; CONTROLLED STUDY; EPIDIDYMIS FAT; GLUCAGON BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLYCOGEN LIVER LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; KETOGENIC DIET; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; GLUCOSE; HOMEOSTASIS; INSULIN; KETOGENIC DIET; LEPTIN; RATS; SIGNAL TRANSDUCTION;

RATTUS;

EID: 79951643124     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2010.010186     Document Type: Article

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