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Volumn 21, Issue 3, 2011, Pages 247-254

Propofol and children - What we know and what we do not know

Author keywords

children; pharmacodynamics; pharmacokinetics; propofol

Indexed keywords

LIVER ENZYME; PROPOFOL;

EID: 79951605297     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/j.1460-9592.2010.03454.x     Document Type: Review
Times cited : (25)

References (60)
  • 1
    • 0025908613 scopus 로고
    • Pharmacokinetic model driven infusion of propofol in children
    • Marsh B, White M, Morton N, et al. Pharmacokinetic model driven infusion of propofol in children. Br J Anaesth 1991; 67: 41-48.
    • (1991) Br J Anaesth , vol.67 , pp. 41-48
    • Marsh, B.1    White, M.2    Morton, N.3
  • 3
    • 0028873823 scopus 로고
    • Propofol pharmacokinetics in children with biliary atresia
    • Raoof AA, van Obbergh LJ, Verbeeck RK,. Propofol pharmacokinetics in children with biliary atresia. Br J Anaesth 1995; 74: 46-49.
    • (1995) Br J Anaesth , vol.74 , pp. 46-49
    • Raoof, A.A.1    Van Obbergh, L.J.2    Verbeeck, R.K.3
  • 6
    • 0029999059 scopus 로고    scopus 로고
    • Pharmacokinetics of propofol after a single dose in children aged 1-3 years with minor burns: Comparison of three data analysis approaches
    • DOI 10.1097/00000542-199603000-00006
    • Murat I, Billard V, Vernois J, et al. Pharmacokinetics of propofol after a single dose in children aged 1-3 years with minor burns. Comparison of three data analysis approaches. Anesthesiology 1996; 84: 526-532. (Pubitemid 26092524)
    • (1996) Anesthesiology , vol.84 , Issue.3 , pp. 526-532
    • Murat, I.1    Billard, V.2    Vernois, J.3    Zaouter, M.4    Marsol, P.5    Souron, R.6    Farinotti, R.7
  • 7
    • 0029812636 scopus 로고    scopus 로고
    • A pharmacokinetically based propofol dosing strategy for sedation of the critically ill, mechanically ventilated pediatric patient
    • Reed MD, Yamashita TS, Marx CM, et al. A pharmacokinetically based propofol dosing strategy for sedation of the critically ill, mechanically ventilated pediatric patient. Crit Care Med 1996; 24: 1473-1481. (Pubitemid 26313747)
    • (1996) Critical Care Medicine , vol.24 , Issue.9 , pp. 1473-1481
    • Reed, M.D.1    Yamashita, T.S.2    Marx, C.M.3    Myers, C.M.4    Blumer, J.L.5
  • 8
    • 18744378263 scopus 로고    scopus 로고
    • Pharmacokinetics of propofol infusions in critically ill neonates, infants, and children in an intensive care unit
    • DOI 10.1097/00000542-200212000-00010
    • Rigby-Jones AE, Nolan JA, Priston MJ, et al. Pharmacokinetics of propofol infusions in critically ill neonates, infants, and children in an intensive care unit. Anesthesiology 2002; 97: 1393-1400. (Pubitemid 35417436)
    • (2002) Anesthesiology , vol.97 , Issue.6 , pp. 1393-1400
    • Rigby-Jones, A.E.1    Nolan, J.A.2    Priston, M.J.3    Wright, P.M.C.4    Sneyd, J.R.5    Wolf, A.R.6
  • 9
    • 33645511875 scopus 로고    scopus 로고
    • Propofol pharmacokinetics and pharmacodynamics for depth of sedation in nonventilated infants after major craniofacial surgery
    • Peeters MY, Prins SA, Knibbe CA, et al. Propofol pharmacokinetics and pharmacodynamics for depth of sedation in nonventilated infants after major craniofacial surgery. Anesthesiology 2006; 104: 466-474.
    • (2006) Anesthesiology , vol.104 , pp. 466-474
    • Peeters, M.Y.1    Prins, S.A.2    Knibbe, C.A.3
  • 11
    • 34748836928 scopus 로고    scopus 로고
    • Maturational pharmacokinetics of single intravenous bolus of propofol
    • DOI 10.1111/j.1460-9592.2007.02285.x
    • Allegaert K, de Hoon J, Verbesselt R, et al. Maturational pharmacokinetics of single intravenous bolus of propofol. Pediatr Anesth 2007; 17: 1028-1034. (Pubitemid 47481127)
    • (2007) Paediatric Anaesthesia , vol.17 , Issue.11 , pp. 1028-1034
    • Allegaert, K.1    Hoon, J.D.2    Verbesselt, R.3    Naulaers, G.4    Murat, I.5
  • 12
    • 17544387018 scopus 로고    scopus 로고
    • Population pharmacokinetics of propofol: A multicenter study
    • Schuttler J, Ihmsen H,. Population pharmacokinetics of propofol: a multicenter study. Anesthesiology 2000; 92: 727-738. (Pubitemid 30130176)
    • (2000) Anesthesiology , vol.92 , Issue.3 , pp. 727-738
    • Schuttler, J.1    Ihmsen, H.2
  • 13
    • 0023605241 scopus 로고
    • Disposition of propofol administered as constant rate intravenous infusions in humans
    • Gepts E, Camu F, Cockshott ID, et al. Disposition of propofol administered as constant rate intravenous infusions in humans. Anesth Analg 1987; 66: 1256-1263. (Pubitemid 18024603)
    • (1987) Anesthesia and Analgesia , vol.66 , Issue.12 , pp. 1256-1263
    • Gepts, E.1    Camu, F.2    Cockshott, I.D.3    Douglas, E.J.4
  • 14
    • 33750344295 scopus 로고    scopus 로고
    • Population clinical pharmacology of children: Modelling covariate effects
    • DOI 10.1007/s00431-006-0189-x
    • Anderson BJ, Allegaert K, Holford NH,. Population clinical pharmacology of children: modelling covariate effects. Eur J Pediatr 2006; 165: 819-829. (Pubitemid 44627767)
    • (2006) European Journal of Pediatrics , vol.165 , Issue.12 , pp. 819-829
    • Anderson, B.J.1    Allegaert, K.2    Holford, N.H.G.3
  • 15
    • 0000664818 scopus 로고
    • Body size and metabolism
    • Kleiber M,. Body size and metabolism. Hilgardia 1932; 6: 315-333.
    • (1932) Hilgardia , vol.6 , pp. 315-333
    • Kleiber, M.1
  • 16
    • 67649415182 scopus 로고    scopus 로고
    • Mechanistic basis of using body size and maturation to predict clearance in humans
    • Anderson BJ, Holford NH,. Mechanistic basis of using body size and maturation to predict clearance in humans. Drug Metab Pharmacokinet 2009; 24: 25-36.
    • (2009) Drug Metab Pharmacokinet , vol.24 , pp. 25-36
    • Anderson, B.J.1    Holford, N.H.2
  • 18
    • 77949354149 scopus 로고    scopus 로고
    • Prediction of propofol clearance in children from an allometric model developed in rats, children and adults versus a 0.75 fixed-exponent allometric model
    • Peeters MY, Allegaert K, Blusse van Oud-Alblas HJ, et al. Prediction of propofol clearance in children from an allometric model developed in rats, children and adults versus a 0.75 fixed-exponent allometric model. Clin Pharmacokinet 2010; 49: 269-275.
    • (2010) Clin Pharmacokinet , vol.49 , pp. 269-275
    • Peeters, M.Y.1    Allegaert, K.2    Blusse Van Oud-Alblas, H.J.3
  • 19
    • 33644860307 scopus 로고    scopus 로고
    • Pharmacokinetics of a single bolus of propofol in Chinese children of different ages
    • Shangguan WN, Lian Q, Aarons L, et al. Pharmacokinetics of a single bolus of propofol in Chinese children of different ages. Anesthesiology 2006; 104: 27-32.
    • (2006) Anesthesiology , vol.104 , pp. 27-32
    • Shangguan, W.N.1    Lian, Q.2    Aarons, L.3
  • 20
    • 0036396419 scopus 로고    scopus 로고
    • Ontogeny of hepatic and renal systemic clearance pathways in infants: Part I
    • Alcorn J, McNamara PJ,. Ontogeny of hepatic and renal systemic clearance pathways in infants: part I. Clin Pharmacokinet 2002; 41: 959-998. (Pubitemid 35168438)
    • (2002) Clinical Pharmacokinetics , vol.41 , Issue.12 , pp. 959-998
    • Alcorn, J.1    McNamara, P.J.2
  • 21
    • 77249173383 scopus 로고    scopus 로고
    • Pediatric models for adult target-controlled infusion pumps
    • Anderson BJ,. Pediatric models for adult target-controlled infusion pumps. Pediatr Anesth 2010; 20: 223-232.
    • (2010) Pediatr Anesth , vol.20 , pp. 223-232
    • Anderson, B.J.1
  • 24
    • 0026781377 scopus 로고
    • Metabolic acidosis and fatal myocardial failure after propofol infusion in children: Five case reports
    • Parke TJ, Stevens JE, Rice AS, et al. Metabolic acidosis and fatal myocardial failure after propofol infusion in children: five case reports. BMJ 1992; 305: 613-616.
    • (1992) BMJ , vol.305 , pp. 613-616
    • Parke, T.J.1    Stevens, J.E.2    Rice, A.S.3
  • 25
    • 0031785577 scopus 로고    scopus 로고
    • Propofol infusion syndrome in children
    • DOI 10.1046/j.1460-9592.1998.00282.x
    • Bray RJ,. Propofol infusion syndrome in children. Paediatr Anaesth 1998; 8: 491-499. (Pubitemid 28523410)
    • (1998) Paediatric Anaesthesia , vol.8 , Issue.6 , pp. 491-499
    • Bray, R.J.1
  • 27
    • 79951666603 scopus 로고    scopus 로고
    • Long term, high dose propofol (Diprivan) infusion
    • MCA/CSM.
    • MCA/CSM. Long term, high dose propofol (Diprivan) infusion. Curr Probl Pharmacovigilence 2001; 27: 6.
    • (2001) Curr Probl Pharmacovigilence , vol.27 , pp. 6
  • 28
    • 0141435823 scopus 로고    scopus 로고
    • Clarification: Propofol (Diprivan) infusion contraindication
    • MCA/CSM.
    • MCA/CSM. Clarification: propofol (Diprivan) infusion contraindication. Curr Probl Pharmacovigilence 2002; 28: 6.
    • (2002) Curr Probl Pharmacovigilence , vol.28 , pp. 6
  • 29
    • 67650116295 scopus 로고    scopus 로고
    • Propofol infusion syndrome: Update of clinical manifestation and pathophysiology
    • Fudickar A, Bein B,. Propofol infusion syndrome: update of clinical manifestation and pathophysiology. Minerva Anestesiol 2009; 75: 339-344.
    • (2009) Minerva Anestesiol , vol.75 , pp. 339-344
    • Fudickar, A.1    Bein, B.2
  • 30
    • 0035941743 scopus 로고    scopus 로고
    • Impaired fatty acid oxidation in propofol infusion syndrome
    • DOI 10.1016/S0140-6736(00)04064-2
    • Wolf A, Weir P, Segar P, et al. Impaired fatty acid oxidation in propofol infusion syndrome. Lancet 2001; 357: 606-607. (Pubitemid 32179617)
    • (2001) Lancet , vol.357 , Issue.9256 , pp. 606-607
    • Wolf, A.1    Weir, P.2    Segar, P.3    Stone, J.4    Shield, J.5
  • 31
    • 2942517655 scopus 로고    scopus 로고
    • A case of propofol toxicity: Further evidence for a causal mechanism
    • DOI 10.1111/j.1460-9592.2004.01299.x
    • Withington DE, Decell MK, Al Ayed T,. A case of propofol toxicity: further evidence for a causal mechanism. Pediatr Anesth 2004; 14: 505-508. (Pubitemid 38758673)
    • (2004) Paediatric Anaesthesia , vol.14 , Issue.6 , pp. 505-508
    • Withington, D.E.1    Decell, M.K.2    Al Ayed, T.3
  • 32
    • 0033981138 scopus 로고    scopus 로고
    • Propofol impairment of mitochondrial respiration isolated perfused guinea pig hearts determined by reflectance spectroscopy
    • Schenkman KA, Yan S,. Propofol impairment of mitochondrial respiration in isolated perfused guinea pig hearts determined by reflectance spectroscopy. Crit Care Med 2000; 28: 172-177. (Pubitemid 30091048)
    • (2000) Critical Care Medicine , vol.28 , Issue.1 , pp. 172-177
    • Schenkman, K.A.1    Yan, S.2
  • 33
    • 34250341834 scopus 로고    scopus 로고
    • Current United Kingdom sedation practice in pediatric intensive care
    • DOI 10.1111/j.1460-9592.2006.02180.x
    • Jenkins IA, Playfor SD, Bevan C, et al. Current United Kingdom sedation practice in pediatric intensive care. Pediatr Anaesth 2007; 17: 675-683. (Pubitemid 46911067)
    • (2007) Paediatric Anaesthesia , vol.17 , Issue.7 , pp. 675-683
    • Jenkins, I.A.1    Playfor, S.D.2    Bevan, C.3    Davies, G.4    Wolf, A.R.5
  • 34
    • 0141962420 scopus 로고    scopus 로고
    • Accuracy of the 'Paedfusor' in children undergoing cardiac surgery or catheterization
    • DOI 10.1093/bja/aeg220
    • Absalom A, Amutike D, Lal A, et al. Accuracy of the 'Paedfusor' in children undergoing cardiac surgery or catheterization. Br J Anaesth 2003; 91: 507-513. (Pubitemid 37258593)
    • (2003) British Journal of Anaesthesia , vol.91 , Issue.4 , pp. 507-513
    • Absalom, A.1    Amutike, D.2    Lal, A.3    White, M.4    Kenny, G.N.C.5
  • 35
    • 21344456740 scopus 로고    scopus 로고
    • 'Paedfusor' pharmacokinetic data set
    • Absalom A, Kenny G,. 'Paedfusor' pharmacokinetic data set. Br J Anaesth 2005; 95: 110.
    • (2005) Br J Anaesth , vol.95 , pp. 110
    • Absalom, A.1    Kenny, G.2
  • 36
    • 41349116390 scopus 로고    scopus 로고
    • The relationship between bispectral index and propofol during target-controlled infusion anesthesia: A comparative study between children and young adults
    • DOI 10.1213/ane.0b013e318164f388, PII 0000053920080400000012
    • Rigouzzo A, Girault L, Louvet N, et al. The relationship between bispectral index and propofol during target-controlled infusion anesthesia: a comparative study between children and young adults. Anesth Analg 2008; 106: 1109-1116. (Pubitemid 351450533)
    • (2008) Anesthesia and Analgesia , vol.106 , Issue.4 , pp. 1109-1116
    • Rigouzzo, A.1    Girault, L.2    Louvet, N.3    Servin, F.4    De-Smet, T.5    Piat, V.6    Seeman, R.7    Murat, I.8    Constant, I.9
  • 37
    • 0041843832 scopus 로고    scopus 로고
    • Using the time of maximum effect site concentration to combine pharmacokinetics and pharmacodynamics
    • DOI 10.1097/00000542-200308000-00014
    • Minto CF, Schnider TW, Gregg KM, et al. Using the time of maximum effect site concentration to combine pharmacokinetics and pharmacodynamics. Anesthesiology 2003; 99: 324-333. (Pubitemid 36909558)
    • (2003) Anesthesiology , vol.99 , Issue.2 , pp. 324-333
    • Minto, C.F.1    Schnider, T.W.2    Gregg, K.M.3    Henthorn, T.K.4    Shafer, S.L.5
  • 38
    • 9444249900 scopus 로고    scopus 로고
    • e0) of propofol in children using the time to peak effect: Comparison with adults
    • Munoz HR, Cortinez LI, Ibacache ME, et al. Estimation of the plasma effect site equilibration rate constant (ke0) of propofol in children using the time to peak effect: comparison with adults. Anesthesiology 2004; 101: 1269-1274. (Pubitemid 39564981)
    • (2004) Anesthesiology , vol.101 , Issue.6 , pp. 1269-1274
    • Munoz, H.R.1    Cortinez, L.I.2    Ibacache, M.E.3    Altermatt, F.R.4
  • 39
    • 0032608599 scopus 로고    scopus 로고
    • Targeting effect compartment or central compartment concentration of propofol: What predicts loss of consciousness?
    • Wakeling HG, Zimmerman JB, Howell S, et al. Targeting effect compartment or central compartment concentration of propofol: what predicts loss of consciousness? Anesthesiology 1999; 90: 92-97.
    • (1999) Anesthesiology , vol.90 , pp. 92-97
    • Wakeling, H.G.1    Zimmerman, J.B.2    Howell, S.3
  • 41
    • 0033825394 scopus 로고    scopus 로고
    • Effect site modelling and its application in TCI
    • Mortier E, Struys M,. Effect site modelling and its application in TCI. Acta Anaesthesiol Belg 2000; 51: 149-152.
    • (2000) Acta Anaesthesiol Belg , vol.51 , pp. 149-152
    • Mortier, E.1    Struys, M.2
  • 42
    • 33748077436 scopus 로고    scopus 로고
    • Pharmacodynamics of propofol in children and adults: Comparison based on the auditory evoked potentials index
    • Cortinez LI, Munoz HR, Lopez R,. Pharmacodynamics of propofol in children and adults: comparison based on the auditory evoked potentials index. Rev Esp Anestesiol Reanim 2006; 53: 289-296.
    • (2006) Rev Esp Anestesiol Reanim , vol.53 , pp. 289-296
    • Cortinez, L.I.1    Munoz, H.R.2    Lopez, R.3
  • 43
    • 0034021319 scopus 로고    scopus 로고
    • Guidelines for the ethical conduct of medical research in children
    • Hull D,. Guidelines for the ethical conduct of medical research in children. Arch Dis Child 2000; 82: 177-182.
    • (2000) Arch Dis Child , vol.82 , pp. 177-182
    • Hull, D.1
  • 44
    • 0027985906 scopus 로고
    • Optimal sedation of mechanically ventilated pediatric critical care patients
    • Marx CM, Smith PG, Lowrie LH, et al. Optimal sedation of mechanically ventilated pediatric critical care patients. Crit Care Med 1994; 22: 163-170.
    • (1994) Crit Care Med , vol.22 , pp. 163-170
    • Marx, C.M.1    Smith, P.G.2    Lowrie, L.H.3
  • 45
    • 1542349960 scopus 로고    scopus 로고
    • Electroencephalograph variables, drug concentrations and sedation scores in children emerging from propofol infusion anaesthesia
    • DOI 10.1046/j.1460-9592.2003.01175.x
    • Murray DM, Thorne GC, Rigby-Jones AE, et al. Electroencephalograph variables, drug concentrations and sedation scores in children emerging from propofol infusion anaesthesia. Pediatr Anesth 2004; 14: 143-151. (Pubitemid 38304894)
    • (2004) Paediatric Anaesthesia , vol.14 , Issue.2 , pp. 143-151
    • Murray, D.M.1    Thorne, G.C.2    Rigby-Jones, A.E.3    Tonucci, D.4    Grimes, S.5    Tooley, M.A.6    Wolf, A.R.7
  • 47
    • 33745870174 scopus 로고    scopus 로고
    • Effect site concentrations of propofol producing hypnosis in children and adults: Comparison using the bispectral index
    • DOI 10.1111/j.1399-6576.2006.01062.x
    • Munoz HR, Cortinez LI, Ibacache ME, et al. Effect site concentrations of propofol producing hypnosis in children and adults: comparison using the bispectral index. Acta Anaesthesiol Scand 2006; 50: 882-887. (Pubitemid 44034241)
    • (2006) Acta Anaesthesiologica Scandinavica , vol.50 , Issue.7 , pp. 882-887
    • Munoz, H.R.1    Cortinez, L.I.2    Ibacache, M.E.3    Leon, P.J.4
  • 48
    • 77955176586 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic modeling of propofol in children
    • Rigouzzo A, Servin F, Constant I,. Pharmacokinetic-pharmacodynamic modeling of propofol in children. Anesthesiology 2010; 113: 343-352.
    • (2010) Anesthesiology , vol.113 , pp. 343-352
    • Rigouzzo, A.1    Servin, F.2    Constant, I.3
  • 49
    • 0031955972 scopus 로고    scopus 로고
    • The influence of method of administration and covariates on the pharmacokinetics of propofol in adult volunteers
    • DOI 10.1097/00000542-199805000-00006
    • Schnider TW, Minto CF, Gambus PL, et al. The influence of method of administration and covariates on the pharmacokinetics of propofol in adult volunteers. Anesthesiology 1998; 88: 1170-1182. (Pubitemid 28216859)
    • (1998) Anesthesiology , vol.88 , Issue.5 , pp. 1170-1182
    • Schnider, T.W.1    Minto, C.F.2    Gambus, P.L.3    Andresen, C.4    Goodale, D.B.5    Shafer, S.L.6    Youngs, E.J.7
  • 50
    • 0035076452 scopus 로고    scopus 로고
    • Investigations of the bispectral index monitor in pediatric anesthesia: First things first
    • Watcha MF,. Investigations of the bispectral index monitor in pediatric anesthesia: first things first. Anesth Analg 2001; 92: 805-807. (Pubitemid 32239113)
    • (2001) Anesthesia and Analgesia , vol.92 , Issue.4 , pp. 805-807
    • Watcha, M.F.1
  • 51
    • 31444450597 scopus 로고    scopus 로고
    • Validation of the Bispectral Index monitor for measuring the depth of sedation in children
    • DOI 10.1213/01.ANE.0000184115.57837.30
    • Sadhasivam S, Ganesh A, Robison A, et al. Validation of the bispectral index monitor for measuring the depth of sedation in children. Anesth Analg 2006; 102: 383-388. (Pubitemid 43152582)
    • (2006) Anesthesia and Analgesia , vol.102 , Issue.2 , pp. 383-388
    • Sadhasivam, S.1    Ganesh, A.2    Robison, A.3    Kaye, R.4    Watcha, M.F.5
  • 53
    • 34247863850 scopus 로고    scopus 로고
    • Monitoring the anaesthetic depth in children - An update
    • DOI 10.1097/ACO.0b013e3280c60c66, PII 0000150320070600000016
    • Davidson AJ,. Monitoring the anaesthetic depth in children-an update. Curr Opin Anaesthesiol 2007; 20: 236-243. (Pubitemid 46701339)
    • (2007) Current Opinion in Anaesthesiology , vol.20 , Issue.3 , pp. 236-243
    • Davidson, A.J.1
  • 54
    • 33846142845 scopus 로고    scopus 로고
    • Comparative evaluation of bispectral index and narcotrend index in children below 5 years of age
    • DOI 10.1111/j.1460-9592.2006.02036.x
    • Wallenborn J, Kluba K, Olthoff D,. Comparative evaluation of Bispectral Index and Narcotrend Index in children below 5 years of age. Pediatr Anesth 2007; 17: 140-147. (Pubitemid 46089379)
    • (2007) Paediatric Anaesthesia , vol.17 , Issue.2 , pp. 140-147
    • Wallenborn, J.1    Kluba, K.2    Olthoff, D.3
  • 55
    • 33645648202 scopus 로고    scopus 로고
    • Spectral entropy as a measure of hypnosis in children
    • Klockars JG, Hiller A, Ranta S, et al. Spectral entropy as a measure of hypnosis in children. Anesthesiology 2006; 104: 708-717.
    • (2006) Anesthesiology , vol.104 , pp. 708-717
    • Klockars, J.G.1    Hiller, A.2    Ranta, S.3
  • 56
    • 27744586305 scopus 로고    scopus 로고
    • Bispectral index monitoring during the administration of neuromuscular blocking agents in the pediatric intensive care unit patient
    • DOI 10.1177/0885066605276806
    • Tobias JD, Grindstaff R,. Bispectral index monitoring during the administration of neuromuscular blocking agents in the pediatric intensive care unit patient. J Intensive Care Med 2005; 20: 233-237. (Pubitemid 43093894)
    • (2005) Journal of Intensive Care Medicine , vol.20 , Issue.4 , pp. 233-237
    • Tobias, J.D.1    Grindstaff, R.2
  • 58
    • 33847642021 scopus 로고    scopus 로고
    • Changes of bispectral index during recovery from general anesthesia with 2% propofol and remifentanil in children
    • DOI 10.1111/j.1460-9592.2006.02096.x
    • Park HJ, Kim YL, Kim CS, et al. Changes of bispectral index during recovery from general anesthesia with 2% propofol and remifentanil in children. Pediatr Anesth 2007; 17: 353-357. (Pubitemid 46365106)
    • (2007) Paediatric Anaesthesia , vol.17 , Issue.4 , pp. 353-357
    • Park, H.-J.1    Kim, Y.L.2    Kim, C.S.3    Kim, S.D.4    Kim, H.-S.5
  • 60
    • 67650708119 scopus 로고    scopus 로고
    • Pharmacokinetic models for propofol - Defining and illuminating the devil in the detail
    • Absalom AR, Mani V, De Smet T, et al. Pharmacokinetic models for propofol - defining and illuminating the devil in the detail. Br J Anaesth 2009; 103: 26-37.
    • (2009) Br J Anaesth , vol.103 , pp. 26-37
    • Absalom, A.R.1    Mani, V.2    De Smet, T.3


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