Estimation of the plasma effect site equilibration rate constant (k e0) of propofol in children using the time to peak effect: Comparison with adults

Anesthesiology

Volumn 101, Issue 6, 2004, Pages 1269-1274

  Muñoz, Hernán R ^a,b   Cortínez, Luis I ^a   Ibacache, Mauricio E ^a   Altermatt, Fernando R ^a  

^a Department of Anesthesiology ^*

^b HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

PROPOFOL;

ADOLESCENT; ADULT; ANESTHESIA; ARTICLE; BOLUS INJECTION; CHILD; CONTROLLED STUDY; DRUG EFFECT; EQUILIBRIUM CONSTANT; FEMALE; HUMAN; MALE; METHODOLOGY; PRIORITY JOURNAL;

EID: 9444249900     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200412000-00005     Document Type: Article

References (11)

1. Egan TD: Target-controlled drug delivery: Progress toward an intravenous "vaporizer" and automated anesthetic administration. ANESTHESIOLOGY 2003; 99:1214-9
2. Wakeling HG, Zimmerman JB, Howell S, Glass PS: Targeting effect compartment or central compartment concentration of propofol: What predicts loss of consciousness? ANESTHESIOLOGY 1999; 90:92-7
3. Struys MM, De Smet T, Depoorter B, Versichelen LF, Mortier EP, Dumortier FJ, Shafer SL, Rolly G: Comparison of plasma compartment versus two methods for effect compartment-controlled target-controlled infusion for propofol. ANESTHESIOLOGY 2000; 92:399-406
4. Billard V, Gambus PL, Chamoun N, Stanski DR, Shafer SL: A comparison of spectral edge, delta power, and bispectral index as EEG measures of alfentanil, propofol, and midazolam drug effect. Clin Pharmacol Ther 1997; 61:45-58
5. e0s of propofol for blood pressure and EEG Bispectral Index in elderly and younger patients. ANESTHESIOLOGY 1999; 90:1517-27
6. Schnider TW, Minto CF, Shafer SL, Gambus PL, Andresen C, Goodale DB, Youngs EJ: The influence of age on propofol pharmacodynamics. ANESTHESIOLOGY 1999; 90:1502-16
7. Shafer SL, Gregg KM: Algorithms to rapidly achieve and maintain stable drug concentrations at the site of drug effect with a computer-controlled infusion pump. J Pharmacokinet Biopharm 1992; 20:147-69
8. Minto CF, Schnider TW, Gregg KM, Henthorn TK, Shafer SL: Using the time of maximum effect site concentration to combine pharmacokinetics and pharmacodynamics. ANESTHESIOLOGY 2003; 99:324-33
9. Schnider TW, Minto CF, Gambus PL, Andresen C, Goodale DB, Shafer SL, Youngs EJ: The influence of method of administration and covariates on the pharmacokinetics of propofol in adult volunteers. ANESTHESIOLOGY 1998; 88:1170-82
10. Kataria BK, Ved SA, Nicodemus HF, Hoy GR, Lea D, Dubois MY, Mandema JW, Shafer SL: The pharmacokinetics of propofol in children using three different data analysis approaches. ANESTHESIOLOGY 1994; 80:104-22
11. Amutike D, Lal A, Absalom A, Kenny GNC. Accuracy of the Paedfusor: A new propofol target-controlled infusion system for children. Br J Anaesth 2001; 87:175P-6P