Allometric relationships between the pharmacokinetics of propofol in rats, children and adults

British Journal of Clinical Pharmacology

Volumn 59, Issue 6, 2005, Pages 705-711

  Knibbe, Catherijne A J ^a   Zuideveld, Klaas P ^b,c   Aarts, Leon P H J ^a   Kuks, Paul F M ^a   Danhof, Meindert ^b  

^a ST ANTONIUS HOSPITAL   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Allometric scaling; Children; Pharmacokinetics; Propofol

Indexed keywords

PROPOFOL;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ALLOMETRY; ANESTHESIA; ARTICLE; BODY WEIGHT; CHEMICAL MODIFICATION; CHILD; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; CRITICAL ILLNESS; DRUG CLEARANCE; HUMAN; INTERMETHOD COMPARISON; MALE; MATHEMATICAL ANALYSIS; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RAT; SEDATION; SIMULATION;

ADULT; AGED; AGING; ANESTHETICS, INTRAVENOUS; ANIMALS; BODY WEIGHT; CHILD, PRESCHOOL; DRUG EVALUATION, PRECLINICAL; HUMANS; INFANT; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; PROPOFOL; RATS; RATS, WISTAR; SPECIES SPECIFICITY;

EID: 20644459235     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2005.02239.x     Document Type: Article

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