Probing cathepsin S activity in whole blood by the activity-based probe BIL-DMK: Cellular distribution in human leukocyte populations and evidence of diurnal modulation

Analytical Biochemistry

Volumn 411, Issue 1, 2011, Pages 43-49

  Veilleux, Alain ^a   Black, W Cameron ^a   Gauthier, Jacques Yves ^a   Mellon, Christophe ^a   Percival, M David ^a   Tawa, Paul ^a   Falgueyret, Jean Pierre ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

Activity based probe; Cathepsin K; Cathepsin S; Diurnal modulation; Enzyme; Enzyme occupancy assay; Leukocytes; Whole blood

Indexed keywords

AMINO ACIDS; CELL CULTURE; CELL PROLIFERATION; CELLS; ELECTROPHORESIS; ENZYMES; MODULATION; PROBES;

ACTIVITY-BASED PROBE; CATHEPSIN K; CATHEPSIN S; LEUKOCYTES; WHOLE BLOOD;

BLOOD;

BIL DMK; CATHEPSIN S; CATHEPSIN S INHIBITOR; DEXTRAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD; BLOOD SAMPLING; CELL POPULATION; CELL SEPARATION; CELLULAR DISTRIBUTION; CIRCADIAN RHYTHM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; ISOELECTRIC POINT; LEUKOCYTE; MOLECULAR PROBE; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING;

MACACA MULATTA;

EID: 79951577371     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2010.11.022     Document Type: Article

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