Role of cathepsin S in ozone-induced airway hyperresponsiveness and inflammation

Pulmonary Pharmacology and Therapeutics

Volumn 22, Issue 1, 2009, Pages 27-32

  Williams, Alison S ^a   Eynott, Paul R ^b   Leung, Sum Yee ^a   Nath, Puneeta ^a   Jupp, Ray ^b   De Sanctis, George T ^b   Resnick, Robert ^b   Adcock, Ian M ^a   Chung, Kian Fan ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b Sanofi Aventis Pharmaceuticals   (United States)

Author keywords

Airway inflammation; Airways hyperresponsiveness; Cathepsin S; Neutrophilia; Oxidative stress; Ozone

Indexed keywords

CATHEPSIN S; CATHEPSIN S INHIBITOR; COMPOUND A; GAMMA INTERFERON; INTERLEUKIN 6; OZONE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AIR; AIRWAY HYPERRESPONSIVENESS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAGG ALBINO MOUSE; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG INHIBITION; INFLAMMATORY CELL; LUNG LAVAGE; MALE; MOUSE; NEUTROPHIL; NEUTROPHILIA; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REGULATORY MECHANISM; RESPIRATORY TRACT DISEASE; RESPIRATORY TRACT INFLAMMATION;

AIR POLLUTANTS; ANIMALS; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE; CATHEPSINS; DRUG DELIVERY SYSTEMS; INFLAMMATION; INTERFERON-GAMMA; INTERLEUKIN-6; MALE; MICE; MICE, INBRED BALB C; NEUTROPHIL INFILTRATION; OXIDATIVE STRESS; OZONE; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 58349121887     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2008.11.002     Document Type: Article

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