-
1
-
-
56449088717
-
A ligand-mediated nanovector for targeted gene delivery and transfection in cancer cells
-
1:CAS:528:DC%2BD1cXhsVensr%2FP 10.1016/j.biomaterials.2008.10.003 18990439
-
O Veiseh FM Kievit JW Gunn BD Ratner M Zhang 2009 A ligand-mediated nanovector for targeted gene delivery and transfection in cancer cells Biomaterials 30 649 657 1:CAS:528:DC%2BD1cXhsVensr%2FP 10.1016/j.biomaterials. 2008.10.003 18990439
-
(2009)
Biomaterials
, vol.30
, pp. 649-657
-
-
Veiseh, O.1
Kievit, F.M.2
Gunn, J.W.3
Ratner, B.D.4
Zhang, M.5
-
2
-
-
33646175307
-
Synthesis and photocytotoxic activity of new chlorin-polyamine conjugates
-
1:CAS:528:DC%2BD28XksFeru7o%3D 10.1016/j.bmcl.2006.03.044 16621548
-
G Garcia V Sol F Lamarche R Granet M Guilloton Y Champavier 2006 Synthesis and photocytotoxic activity of new chlorin-polyamine conjugates Bioorg Med Chem Lett 16 3188 3192 1:CAS:528:DC%2BD28XksFeru7o%3D 10.1016/j.bmcl.2006. 03.044 16621548
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 3188-3192
-
-
Garcia, G.1
Sol, V.2
Lamarche, F.3
Granet, R.4
Guilloton, M.5
Champavier, Y.6
-
3
-
-
30544437848
-
Effect of polyamine homologation on the transport and biological properties of heterocyclic amidines
-
DOI 10.1021/jm050018q
-
JG Delcros S Tomasi S Duhieu M Foucault B Martin M Le Roch 2006 Effect of polyamine homologation on the transport and biological properties of heterocyclic amidines J Med Chem 49 232 245 1:CAS:528:DC%2BD2MXht1KktrbO 10.1021/jm050018q 16392808 (Pubitemid 43078592)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.1
, pp. 232-245
-
-
Delcros, J.-G.1
Tomasi, S.2
Duhieu, S.3
Foucault, M.4
Martin, B.5
Le Roch, M.6
Eifler-Lima, V.7
Renault, J.8
Uriac, P.9
-
4
-
-
34248228763
-
Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases
-
DOI 10.1038/nrd2243, PII NRD2243
-
RA Casero LJ Marton 2007 Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases Nat Rev Drug Discov 6 373 390 1:CAS:528:DC%2BD2sXkslyiu7k%3D 10.1038/nrd2243 17464296 (Pubitemid 46705201)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.5
, pp. 373-390
-
-
Casero, R.A.1
Marton, L.J.2
-
5
-
-
34547678624
-
Structure-activity investigations of polyamine-anthracene conjugates and their uptake via the polyamine transporter
-
DOI 10.1007/s00726-007-0527-y, Special Issue: Polyamines and their Analogs in Cancer and other Diseases
-
O Phanstiel IV N Kaur JG Delcros 2007 Structure-activity investigations of polyamine-anthracene conjugates and their uptake via the polyamine transporter Amino Acids 33 305 313 1:CAS:528:DC%2BD2sXos1eqtrc%3D 10.1007/s00726-007-0527-y 17410331 (Pubitemid 47222973)
-
(2007)
Amino Acids
, vol.33
, Issue.2
, pp. 305-313
-
-
Phanstiel IV, O.1
Kaur, N.2
Delcros, J.-G.3
-
6
-
-
57149094031
-
F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system
-
1:CAS:528:DC%2BD1cXhsVegtbnN 10.1158/0008-5472.CAN-08-2748 19047165
-
JM Barret A Kruczynski S Vispé JP Annereau V Brel Y Guminski 2008 F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system Cancer Res 68 9845 9853 1:CAS:528:DC%2BD1cXhsVegtbnN 10.1158/0008-5472.CAN-08-2748 19047165
-
(2008)
Cancer Res
, vol.68
, pp. 9845-9853
-
-
Barret, J.M.1
Kruczynski, A.2
Vispé, S.3
Annereau, J.P.4
Brel, V.5
Guminski, Y.6
-
7
-
-
0026570051
-
Evaluation of amonafide in cervical cancer, phase II: A swog study
-
1:STN:280:DyaK387pslGluw%3D%3D 10.1097/00000421-199202000-00009 1550078
-
VK Malviya PY Liu DS Alberts EA Surwit JB Craig EV Hanningan 1992 Evaluation of amonafide in cervical cancer, phase II: a swog study Am J Clin Oncol 15 41 44 1:STN:280:DyaK387pslGluw%3D%3D 10.1097/00000421-199202000-00009 1550078
-
(1992)
Am J Clin Oncol
, vol.15
, pp. 41-44
-
-
Malviya, V.K.1
Liu, P.Y.2
Alberts, D.S.3
Surwit, E.A.4
Craig, J.B.5
Hanningan, E.V.6
-
8
-
-
57949098095
-
Synthese, cytotoxicity and apoptosis of naphthalimide-polyamine conjugates as antitumor agents
-
1:CAS:528:DC%2BD1MXlvFaj 10.1016/j.ejmech.2008.02.044 18423800
-
ZY Tian SQ Xie YW Du YF Ma J Zhao WY Gao 2009 Synthese, cytotoxicity and apoptosis of naphthalimide-polyamine conjugates as antitumor agents Eur J Med Chem 44 393 399 1:CAS:528:DC%2BD1MXlvFaj 10.1016/j.ejmech.2008.02.044 18423800
-
(2009)
Eur J Med Chem
, vol.44
, pp. 393-399
-
-
Tian, Z.Y.1
Xie, S.Q.2
Du, Y.W.3
Ma, Y.F.4
Zhao, J.5
Gao, W.Y.6
-
9
-
-
68549085062
-
Polyamine transporter recognization and antitumor effects of anthracenymethyl homospermidin
-
1:CAS:528:DC%2BD1MXhtVSmt7rI 10.1016/j.tox.2009.07.001
-
SQ Xie JH Wang HX Ma PF Cheng J Zhao CJ Wang 2009 Polyamine transporter recognization and antitumor effects of anthracenymethyl homospermidin Toxicol 263 127 133 1:CAS:528:DC%2BD1MXhtVSmt7rI 10.1016/j.tox.2009.07.001
-
(2009)
Toxicol
, vol.263
, pp. 127-133
-
-
Xie, S.Q.1
Wang, J.H.2
Ma, H.X.3
Cheng, P.F.4
Zhao, J.5
Wang, C.J.6
-
10
-
-
34548101628
-
Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison
-
DOI 10.1016/j.bcp.2007.07.003, PII S0006295207004248
-
CR Arthur JT Gupton GE Kellogg WA Yeudall MC Cabot IF Newsham 2007 Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison Biochem Pharmacol 74 981 991 1:CAS:528:DC%2BD2sXpsFGqsbw%3D 10.1016/j.bcp.2007.07.003 17692290 (Pubitemid 47287680)
-
(2007)
Biochemical Pharmacology
, vol.74
, Issue.7
, pp. 981-991
-
-
Arthur, C.R.1
Gupton, J.T.2
Kellogg, G.E.3
Yeudall, W.A.4
Cabot, M.C.5
Newsham, I.F.6
Gewirtz, D.A.7
-
11
-
-
0036334069
-
Different effects of chloroquine and hydroxychloroquine on lysosomal function in cultured retinal pigment epithelial cells
-
DOI 10.1034/j.1600-0463.2002.100606.x
-
SP Sundelin A Terman 2002 Different effects of chloroquine and hydroxychloroquine on lysosomal function in cultured retinal pigment epithelial cells APMIS 110 481 489 1:CAS:528:DC%2BD38XmslOlurs%3D 10.1034/j.1600-0463.2002. 100606.x 12193209 (Pubitemid 34856490)
-
(2002)
APMIS
, vol.110
, Issue.6
, pp. 481-489
-
-
Sundelin, S.P.1
Terman, A.2
-
12
-
-
77949331349
-
CHM-1, a new vascular targeting agent, induces apoptosis of human umbilical vein endothelial cells via p53-mediated death receptor 5 up-regulation
-
1:CAS:528:DC%2BC3cXhvFCrtLc%3D 10.1074/jbc.M109.036277 20007968
-
AC Tsai SL Pan HL Sun CY Wang CY Peng SW Wang 2010 CHM-1, a new vascular targeting agent, induces apoptosis of human umbilical vein endothelial cells via p53-mediated death receptor 5 up-regulation J Biol Chem 285 5497 5506 1:CAS:528:DC%2BC3cXhvFCrtLc%3D 10.1074/jbc.M109.036277 20007968
-
(2010)
J Biol Chem
, vol.285
, pp. 5497-5506
-
-
Tsai, A.C.1
Pan, S.L.2
Sun, H.L.3
Wang, C.Y.4
Peng, C.Y.5
Wang, S.W.6
-
13
-
-
77953072049
-
The polyamine transport system as a target for anticancer drug development
-
1:CAS:528:DC%2BC3cXhs1OjsL4%3D 10.1007/s00726-009-0400-2 19956998
-
AJ Palmer HM Wallace 2010 The polyamine transport system as a target for anticancer drug development Amino Acids 38 415 422 1:CAS:528: DC%2BC3cXhs1OjsL4%3D 10.1007/s00726-009-0400-2 19956998
-
(2010)
Amino Acids
, vol.38
, pp. 415-422
-
-
Palmer, A.J.1
Wallace, H.M.2
-
14
-
-
57349144337
-
Bisnaphthalimidopropyl spermidine induces apoptosis within colon carcinoma cells
-
1:CAS:528:DC%2BD1cXhsV2gtr3I 10.1016/j.cbi.2008.09.033 18983836
-
LD Ralton CS Bestwick L Milne S Duthie P Kong Thoo Lin 2009 Bisnaphthalimidopropyl spermidine induces apoptosis within colon carcinoma cells Chem Biol Interact 177 1 6 1:CAS:528:DC%2BD1cXhsV2gtr3I 10.1016/j.cbi.2008.09. 033 18983836
-
(2009)
Chem Biol Interact
, vol.177
, pp. 1-6
-
-
Ralton, L.D.1
Bestwick, C.S.2
Milne, L.3
Duthie, S.4
Kong Thoo Lin, P.5
-
15
-
-
0034045972
-
Involvement of polyamines in apoptosis. Facts and controversies: Effectors or protectors?
-
DOI 10.1006/scbi.2000.0308
-
RG Schipper LC Penning AA Verhofstad 2000 Involvement of polyamines in apoptosis. Facts and controversies: effectors or protectors? Semin Cancer Biol 10 55 68 1:CAS:528:DC%2BD3cXkvFWkt7k%3D 10.1006/scbi.2000.0308 10888272 (Pubitemid 30391957)
-
(2000)
Seminars in Cancer Biology
, vol.10
, Issue.1
, pp. 55-68
-
-
Schipper, R.G.1
Penning, L.C.2
Verhofstad, A.A.J.3
-
16
-
-
35648992556
-
A novel homospermidine conjugate inhibits growth and induces apoptosis in human hepatoma cells
-
DOI 10.1111/j.1745-7254.2007.00639.x
-
SQ Xie YL Wu PF Cheng MW Wang GC Liu YF Ma J Zhao CJ Wang 2007 A novel homospermidine conjugate inhibits growth and induces apoptosis in human hepatoma cells Acta Pharmacol Sin 28 1827 1834 1:CAS:528:DC%2BD2sXhtlGmsLrP 10.1111/j.1745-7254.2007.00639.x 17959035 (Pubitemid 350029321)
-
(2007)
Acta Pharmacologica Sinica
, vol.28
, Issue.11
, pp. 1827-1834
-
-
Xie, S.-Q.1
Wu, Y.-L.2
Cheng, P.-F.3
Wang, M.-W.4
Liu, G.-C.5
Ma, Y.-F.6
Zhao, J.7
Wang, C.-J.8
-
17
-
-
70350678496
-
Conjugation of substituted naphthalimides to polyamines as cytotoxic agents targeting the Akt/mTOR signal pathway
-
1:CAS:528:DC%2BD1MXhtleit7vJ 10.1039/b912685f 19865701
-
ZY Tian SQ Xie ZH Mei J Zhao WY Gao CJ Wang 2009 Conjugation of substituted naphthalimides to polyamines as cytotoxic agents targeting the Akt/mTOR signal pathway Org Biomol Chem 7 4651 4660 1:CAS:528:DC%2BD1MXhtleit7vJ 10.1039/b912685f 19865701
-
(2009)
Org Biomol Chem
, vol.7
, pp. 4651-4660
-
-
Tian, Z.Y.1
Xie, S.Q.2
Mei, Z.H.3
Zhao, J.4
Gao, W.Y.5
Wang, C.J.6
-
18
-
-
77950501014
-
MTOR regulation of autophagy
-
1:CAS:528:DC%2BC3cXjs12nu74%3D 10.1016/j.febslet.2010.01.017 20083114
-
CH Jung SH Ro J Cao NM Otto DH Kim 2010 mTOR regulation of autophagy FEBS Lett 584 1287 1295 1:CAS:528:DC%2BC3cXjs12nu74%3D 10.1016/j.febslet.2010.01.017 20083114
-
(2010)
FEBS Lett
, vol.584
, pp. 1287-1295
-
-
Jung, C.H.1
Ro, S.H.2
Cao, J.3
Otto, N.M.4
Kim, D.H.5
-
19
-
-
77950252174
-
Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1
-
1:CAS:528:DC%2BC3cXjvVShur0%3D 10.1038/onc.2009.519 20101204
-
M Djavaheri-Mergny MC Maiuri G Kroemer 2010 Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1 Oncogene 29 1717 1719 1:CAS:528:DC%2BC3cXjvVShur0%3D 10.1038/onc.2009.519 20101204
-
(2010)
Oncogene
, vol.29
, pp. 1717-1719
-
-
Djavaheri-Mergny, M.1
Maiuri, M.C.2
Kroemer, G.3
-
20
-
-
33846077612
-
Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1
-
DOI 10.1016/j.leukres.2006.06.021, PII S0145212606002475
-
WB Qian JQ Liu J Jin WM Ni WL Xu 2007 Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via upregulation of Beclin-1 Leuk. Res 31 329 339 10.1016/j.leukres.2006.06.021 16882451 (Pubitemid 46073178)
-
(2007)
Leukemia Research
, vol.31
, Issue.3
, pp. 329-339
-
-
Qian, W.1
Liu, J.2
Jin, J.3
Ni, W.4
Xu, W.5
-
21
-
-
57049110368
-
Involvement of PKC signal pathways in oridonin-induced autophagy in HeLa cells: A protective mechanism against apoptosis
-
1:CAS:528:DC%2BD1cXhsVOisLrO 10.1016/j.bbrc.2008.11.038 19026988
-
Y Zhang Y Wu S Tashiro S Onodera T Ikejima 2009 Involvement of PKC signal pathways in oridonin-induced autophagy in HeLa cells: a protective mechanism against apoptosis Biochem Biophys Res Commun 378 273 278 1:CAS:528: DC%2BD1cXhsVOisLrO 10.1016/j.bbrc.2008.11.038 19026988
-
(2009)
Biochem Biophys Res Commun
, vol.378
, pp. 273-278
-
-
Zhang, Y.1
Wu, Y.2
Tashiro, S.3
Onodera, S.4
Ikejima, T.5
-
22
-
-
23944478449
-
Mitochondria: A novel target for the chemoprevention of cancer
-
DOI 10.1007/s10495-005-0792-8
-
Hail NJr 2005 Mitochondria: a novel target for the chemoprevention of cancer Apoptosis 10 687 705 10.1007/s10495-005-0792-8 (Pubitemid 41187069)
-
(2005)
Apoptosis
, vol.10
, Issue.4
, pp. 687-705
-
-
Hail Jr., N.1
-
23
-
-
30544436579
-
A small molecule compound inhibits AKT pathway in ovarian cancer cell lines
-
DOI 10.1016/j.ygyno.2005.08.044, PII S0090825805007237
-
HJ Tang X Jin S Wang D Yang Y Cao J Chen 2006 A small molecule compound inhibits AKT pathway in ovarian cancer cell lines Gynecol Oncol 100 308 317 1:CAS:528:DC%2BD28XjsFKrtQ%3D%3D 10.1016/j.ygyno.2005.08.044 16209885 (Pubitemid 43078483)
-
(2006)
Gynecologic Oncology
, vol.100
, Issue.2
, pp. 308-317
-
-
Tang, H.-J.1
Jin, X.2
Wang, S.3
Yang, D.4
Cao, Y.5
Chen, J.6
Gossett, D.R.7
Lin, J.8
-
24
-
-
39049171988
-
Novel anti-apoptotic effect of Bcl-2: Prevention of polyamine depletion-induced cell death
-
DOI 10.1016/j.cellbi.2007.08.011, PII S1065699507002107
-
CM Holst VM Johansson K Alm SM Oredsson 2008 Novel anti-apoptotic effect of Bcl-2: prevention of polyamine depletion-induced cell death Cell Biol Int 32 66 74 1:CAS:528:DC%2BD1cXitlKit7k%3D 10.1016/j.cellbi.2007.08.011 17920946 (Pubitemid 351249140)
-
(2008)
Cell Biology International
, vol.32
, Issue.1
, pp. 66-74
-
-
Holst, C.M.1
Johansson, V.M.2
Alm, K.3
Oredsson, S.M.4
-
25
-
-
52649141739
-
Molecular mechanisms underlying N1, N11-diethylnorspermine-induced apoptosis in a human breast cancer cell line
-
1:CAS:528:DC%2BD1cXhtVGktLzM 10.1097/CAD.0b013e32830f902b 18766001
-
CM Holst J Staaf G Jönsson C Hegardt SM Oredsson 2008 Molecular mechanisms underlying N1, N11-diethylnorspermine-induced apoptosis in a human breast cancer cell line Anticancer Drugs 19 871 883 1:CAS:528:DC%2BD1cXhtVGktLzM 10.1097/CAD.0b013e32830f902b 18766001
-
(2008)
Anticancer Drugs
, vol.19
, pp. 871-883
-
-
Holst, C.M.1
Staaf, J.2
Jönsson, G.3
Hegardt, C.4
Oredsson, S.M.5
-
26
-
-
38549141763
-
Synergistic antitumor effects of anthracenylmethyl homospermidine and alpha-difluoromethylornithine on promyelocytic leukemia HL60 cells
-
DOI 10.1016/j.tiv.2007.09.017, PII S0887233307002615
-
SQ Xie GC Liu YF Ma PF Cheng YL Wu MW Wang J Zhao CJ Wang 2008 Synergistic antitumor effects of anthracenylmethyl homospermidine and alpha-difluoromethylornithine on promyelocytic leukemia HL60 cells Toxicol In Vitro 22 352 358 1:CAS:528:DC%2BD1cXhsFygtrw%3D 10.1016/j.tiv.2007.09.017 17993255 (Pubitemid 351163540)
-
(2008)
Toxicology in Vitro
, vol.22
, Issue.2
, pp. 352-358
-
-
Xie, S.-Q.1
Liu, G.-C.2
Ma, Y.-F.3
Cheng, P.-F.4
Wu, Y.-L.5
Wang, M.-W.6
Ji, B.-S.7
Zhao, J.8
Wang, C.-J.9
-
27
-
-
0030584088
-
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
-
DOI 10.1016/S0092-8674(00)81382-3
-
J Zha H Harada E Yang J Jockel SJ Korsmeyer 1996 Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-XL Cell 87 589 592 10.1016/S0092-8674(00)81382-3 (Pubitemid 26386936)
-
(1996)
Cell
, vol.87
, Issue.4
, pp. 619-628
-
-
Zha, J.1
Harada, H.2
Yang, E.3
Jockel, J.4
Korsmeyer, S.J.5
|