메뉴 건너뛰기




Volumn 22, Issue 1-2, 2011, Pages 43-54

The immunity-related GTPases in mammals: A fast-evolving cell-autonomous resistance system against intracellular pathogens

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 5; GUANOSINE TRIPHOSPHATASE; IMMUNITY RELATED GUANOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG;

EID: 79951552359     PISSN: 09388990     EISSN: 14321777     Source Type: Journal    
DOI: 10.1007/s00335-010-9293-3     Document Type: Article
Times cited : (93)

References (86)
  • 1
    • 84864290306 scopus 로고    scopus 로고
    • IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy
    • 10.1371/journal.pone.0004588 19242543
    • MA Al-Zeer HM Al-Younes PR Braun J Zerrahn TF Meyer 2009 IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy PLoS One 4 e4588 10.1371/journal.pone.0004588 19242543
    • (2009) PLoS One , vol.4 , pp. 4588
    • Al-Zeer, M.A.1    Al-Younes, H.M.2    Braun, P.R.3    Zerrahn, J.4    Meyer, T.F.5
  • 2
    • 0017081605 scopus 로고
    • Strain-dependent differences in murine susceptibility to toxoplasma
    • 1:STN:280:DyaE287ovFektw%3D%3D 1270155
    • FG Araujo DM Williams FC Grumet JS Remington, et al. 1976 Strain-dependent differences in murine susceptibility to toxoplasma Infect Immun 13 5 1528 1530 1:STN:280:DyaE287ovFektw%3D%3D 1270155
    • (1976) Infect Immun , vol.13 , Issue.5 , pp. 1528-1530
    • Araujo, F.G.1    Williams, D.M.2    Grumet, F.C.3    Remington, J.S.4
  • 3
    • 57649215874 scopus 로고    scopus 로고
    • GTPase cycle of dynamin is coupled to membrane squeeze and release, leading to spontaneous fission
    • 1:CAS:528:DC%2BD1MXisFyisw%3D%3D 10.1016/j.cell.2008.11.028 19084269
    • PV Bashkirov SA Akimov AI Evseev SL Schmid J Zimmerberg, et al. 2008 GTPase cycle of dynamin is coupled to membrane squeeze and release, leading to spontaneous fission Cell 135 1276 1286 1:CAS:528:DC%2BD1MXisFyisw%3D%3D 10.1016/j.cell.2008.11.028 19084269
    • (2008) Cell , vol.135 , pp. 1276-1286
    • Bashkirov, P.V.1    Akimov, S.A.2    Evseev, A.I.3    Schmid, S.L.4    Zimmerberg, J.5
  • 4
    • 33744509713 scopus 로고    scopus 로고
    • The interferon-inducible p47 (IRG) GTPases in vertebrates: Loss of the cell autonomous resistance mechanism in the human lineage
    • 10.1186/gb-2005-6-11-r92 16277747
    • C Bekpen JP Hunn C Rohde I Parvanova L Guethlein, et al. 2005 The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage Genome Biol 6 R92 10.1186/gb-2005-6-11-r92 16277747
    • (2005) Genome Biol , vol.6 , pp. 92
    • Bekpen, C.1    Hunn, J.P.2    Rohde, C.3    Parvanova, I.4    Guethlein, L.5
  • 5
    • 62149128961 scopus 로고    scopus 로고
    • Death and resurrection of the human IRGM gene
    • 10.1371/journal.pgen.1000403 19266026
    • C Bekpen T Marques-Bonet C Alkan F Antonacci MB Leogrande, et al. 2009 Death and resurrection of the human IRGM gene PLoS Genet 5 e1000403 10.1371/journal.pgen.1000403 19266026
    • (2009) PLoS Genet , vol.5 , pp. 1000403
    • Bekpen, C.1    Marques-Bonet, T.2    Alkan, C.3    Antonacci, F.4    Leogrande, M.B.5
  • 9
    • 0027732538 scopus 로고
    • Proteins regulating Ras and its relatives
    • DOI 10.1038/366643a0
    • MS Boguski F McCormick 1993 Proteins regulating Ras and its relatives Nature 366 643 654 1:CAS:528:DyaK2cXnt1SisQ%3D%3D 10.1038/366643a0 8259209 (Pubitemid 24036012)
    • (1993) Nature , vol.366 , Issue.6456 , pp. 643-654
    • Boguski, M.S.1    McCormick, F.2
  • 10
    • 0036342974 scopus 로고    scopus 로고
    • Population biology of Toxoplasma gondii and its relevance to human infection: Do different strains cause different disease?
    • 10.1016/S1369-5274(02)00349-1 12160866
    • JC Boothroyd ME Grigg 2002 Population biology of Toxoplasma gondii and its relevance to human infection: do different strains cause different disease? Curr Opin Microbiol 5 438 442 10.1016/S1369-5274(02)00349-1 12160866
    • (2002) Curr Opin Microbiol , vol.5 , pp. 438-442
    • Boothroyd, J.C.1    Grigg, M.E.2
  • 11
    • 68649128145 scopus 로고    scopus 로고
    • A role for lipid bodies in the cross-presentation of phagocytosed antigens by MHC class i in dendritic cells
    • 1:CAS:528:DC%2BD1MXhtFOgsL7J 10.1016/j.immuni.2009.06.022 19699172
    • L Bougneres J Helft S Tiwari P Vargas BH Chang, et al. 2009 A role for lipid bodies in the cross-presentation of phagocytosed antigens by MHC class I in dendritic cells Immunity 31 232 244 1:CAS:528:DC%2BD1MXhtFOgsL7J 10.1016/j.immuni.2009.06.022 19699172
    • (2009) Immunity , vol.31 , pp. 232-244
    • Bougneres, L.1    Helft, J.2    Tiwari, S.3    Vargas, P.4    Chang, B.H.5
  • 14
    • 56249135538 scopus 로고    scopus 로고
    • A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
    • 1:CAS:528:DC%2BD1cXhtlKmtL%2FI 10.1038/nature07416 18849966
    • K Cadwell JY Liu SL Brown H Miyoshi J Loh, et al. 2008 A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells Nature 456 259 263 1:CAS:528:DC%2BD1cXhtlKmtL%2FI 10.1038/nature07416 18849966
    • (2008) Nature , vol.456 , pp. 259-263
    • Cadwell, K.1    Liu, J.Y.2    Brown, S.L.3    Miyoshi, H.4    Loh, J.5
  • 15
    • 0028835390 scopus 로고
    • Isolation of a gene encoding a developmentally regulated T cell-specific protein with a guanine nucleotide triphosphate-binding motif
    • 1:CAS:528:DyaK2MXjs1art78%3D 7836757
    • DA Carlow J Marth I Clark-Lewis HS Teh 1995 Isolation of a gene encoding a developmentally regulated T cell-specific protein with a guanine nucleotide triphosphate-binding motif J Immunol 154 1724 1734 1:CAS:528:DyaK2MXjs1art78%3D 7836757
    • (1995) J Immunol , vol.154 , pp. 1724-1734
    • Carlow, D.A.1    Marth, J.2    Clark-Lewis, I.3    Teh, H.S.4
  • 16
    • 39049191429 scopus 로고    scopus 로고
    • The rat Toxo1 locus controls the outcome of the toxoplasmic infection according to a mendelian mode
    • P Cavailles C Bisanz O Papapietro C Colacios V Sergent, et al. 2006 The rat Toxo1 locus controls the outcome of the toxoplasmic infection according to a mendelian mode Med Sci (Paris) 22 679 680
    • (2006) Med Sci (Paris) , vol.22 , pp. 679-680
    • Cavailles, P.1    Bisanz, C.2    Papapietro, O.3    Colacios, C.4    Sergent, V.5
  • 17
    • 77956482589 scopus 로고    scopus 로고
    • Identification of a novel IRGM promoter single nucleotide polymorphism associated with tuberculosis
    • 1:CAS:528:DC%2BC3cXhtFGhtL7P 10.1016/j.cca.2010.06.009 20547146
    • N Che S Li T Gao Z Zhang Y Han, et al. 2010 Identification of a novel IRGM promoter single nucleotide polymorphism associated with tuberculosis Clin Chim Acta 411 21-22 1645 1649 1:CAS:528:DC%2BC3cXhtFGhtL7P 10.1016/j.cca.2010. 06.009 20547146
    • (2010) Clin Chim Acta , vol.411 , Issue.2122 , pp. 1645-1649
    • Che, N.1    Li, S.2    Gao, T.3    Zhang, Z.4    Han, Y.5
  • 18
    • 75949090239 scopus 로고    scopus 로고
    • IFN-inducible p47 GTPases display differential responses to Schistosoma japonicum acute infection
    • 1:CAS:528:DC%2BC3cXht1Kktr8%3D 10.1038/cmi.2009.100 20029464
    • X Chen X Du M Zhang D Zhang M Ji, et al. 2010 IFN-inducible p47 GTPases display differential responses to Schistosoma japonicum acute infection Cell Mol Immunol 7 1 69 76 1:CAS:528:DC%2BC3cXht1Kktr8%3D 10.1038/cmi.2009.100 20029464
    • (2010) Cell Mol Immunol , vol.7 , Issue.1 , pp. 69-76
    • Chen, X.1    Du, X.2    Zhang, M.3    Zhang, D.4    Ji, M.5
  • 19
    • 44449088023 scopus 로고    scopus 로고
    • Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10
    • 1:CAS:528:DC%2BD1cXkvVCjtrk%3D 18424746
    • J Coers I Bernstein-Hanley D Grotsky I Parvanova JC Howard, et al. 2008 Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10 J Immunol 180 6237 6245 1:CAS:528:DC%2BD1cXkvVCjtrk%3D 18424746
    • (2008) J Immunol , vol.180 , pp. 6237-6245
    • Coers, J.1    Bernstein-Hanley, I.2    Grotsky, D.3    Parvanova, I.4    Howard, J.C.5
  • 20
    • 0035898464 scopus 로고    scopus 로고
    • Inactivation of LRG-47 and IRG-47 reveals a family of interferon γ-inducible genes with essential, pathogen-specific roles in resistance to infection
    • DOI 10.1084/jem.194.2.181
    • CM Collazo GS Yap GD Sempowski KC Lusby L Tessarollo, et al. 2001 Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection J Exp Med 194 181 188 1:CAS:528:DC%2BD3MXlsVCksbY%3D 10.1084/jem.194.2.181 11457893 (Pubitemid 32673351)
    • (2001) Journal of Experimental Medicine , vol.194 , Issue.2 , pp. 181-187
    • Collazo, C.M.1    Yap, G.S.2    Sempowski, G.D.3    Lusby, K.C.4    Tessarollo, L.5    Vande Woude, G.F.6    Sher, A.7    Taylor, G.A.8
  • 22
    • 77950405093 scopus 로고    scopus 로고
    • Genome-wide association study of CNVs in 16, 000 cases of eight common diseases and 3, 000 shared controls
    • 1:CAS:528:DC%2BC3cXktVygsb4%3D 10.1038/nature08979 20360734
    • N Craddock ME Hurles N Cardin RD Pearson V Plagnol, et al. 2010 Genome-wide association study of CNVs in 16, 000 cases of eight common diseases and 3, 000 shared controls Nature 464 713 720 1:CAS:528:DC%2BC3cXktVygsb4%3D 10.1038/nature08979 20360734
    • (2010) Nature , vol.464 , pp. 713-720
    • Craddock, N.1    Hurles, M.E.2    Cardin, N.3    Pearson, R.D.4    Plagnol, V.5
  • 23
    • 38849193453 scopus 로고    scopus 로고
    • Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense
    • 1:CAS:528:DC%2BD2sXhtlajt7jM 18025219
    • D Degrandi C Konermann C Beuter-Gunia A Kresse J Wurthner, et al. 2007 Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense J Immunol 179 7729 7740 1:CAS:528:DC%2BD2sXhtlajt7jM 18025219
    • (2007) J Immunol , vol.179 , pp. 7729-7740
    • Degrandi, D.1    Konermann, C.2    Beuter-Gunia, C.3    Kresse, A.4    Wurthner, J.5
  • 24
    • 0346998051 scopus 로고    scopus 로고
    • Absence of Interferon-γ-Inducible Gene IGTP Does Not Significantly Alter the Development of Chagasic Cardiomyopathy in Mice Infected with Trypanosoma cruzi (Brazil Strain)
    • DOI 10.1645/GE-3185RN
    • AP de Souza B Tang HB Tanowitz SM Factor V Shtutin J Shirani GA Taylor LM Weiss LA Jelicks 2003 Absence of interferon-gamma-inducible gene IGTP does not significantly alter the development of chagasic cardiomyopathy in mice infected with Trypanosoma cruzi (Brazil strain) J Parasitol 89 1237 1239 1:STN:280:DC%2BD2c%2FktVKlug%3D%3D 10.1645/GE-3185RN 14740917 (Pubitemid 38049816)
    • (2003) Journal of Parasitology , vol.89 , Issue.6 , pp. 1237-1239
    • De Souza, A.P.1    Tang, B.2    Tanowitz, H.B.3    Factor, S.M.4    Shtutin, V.5    Shirani, J.6    Taylor, G.A.7    Weiss, L.M.8    Jelicks, L.A.9
  • 26
    • 37549048915 scopus 로고    scopus 로고
    • The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation
    • 1:CAS:528:DC%2BD1cXhtFOlt7c%3D 10.1016/j.stem.2007.10.007 18371424
    • CG Feng DC Weksberg GA Taylor A Sher MA Goodell 2008 The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation Cell Stem Cell 2 83 89 1:CAS:528:DC%2BD1cXhtFOlt7c%3D 10.1016/j.stem.2007.10.007 18371424
    • (2008) Cell Stem Cell , vol.2 , pp. 83-89
    • Feng, C.G.1    Weksberg, D.C.2    Taylor, G.A.3    Sher, A.4    Goodell, M.A.5
  • 27
    • 54549089752 scopus 로고    scopus 로고
    • The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death
    • 1:CAS:528:DC%2BD1cXht1KrtbjN 10.1038/ni.1653 18806793
    • CG Feng L Zheng D Jankovic A Bafica JL Cannons, et al. 2008 The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death Nat Immunol 9 1279 1287 1:CAS:528:DC%2BD1cXht1KrtbjN 10.1038/ni.1653 18806793
    • (2008) Nat Immunol , vol.9 , pp. 1279-1287
    • Feng, C.G.1    Zheng, L.2    Jankovic, D.3    Bafica, A.4    Cannons, J.L.5
  • 28
    • 77953028450 scopus 로고    scopus 로고
    • Structural basis of oligomerization in the stalk region of dynamin-like MxA
    • 1:CAS:528:DC%2BC3cXltlWmsr4%3D 10.1038/nature08972 20428112
    • S Gao A von der Malsburg S Paeschke J Behlke O Haller, et al. 2010 Structural basis of oligomerization in the stalk region of dynamin-like MxA Nature 465 502 506 1:CAS:528:DC%2BC3cXltlWmsr4%3D 10.1038/nature08972 20428112
    • (2010) Nature , vol.465 , pp. 502-506
    • Gao, S.1    Von Der Malsburg, A.2    Paeschke, S.3    Behlke, J.4    Haller, O.5
  • 29
    • 4444322564 scopus 로고    scopus 로고
    • Crystal structure of IIGP1: A paradigm for interferon-inducible p47 resistance GTPases
    • DOI 10.1016/j.molcel.2004.07.017, PII S1097276504004393
    • A Ghosh R Uthaiah J Howard C Herrmann E Wolf 2004 Crystal structure of IIGP1: a paradigm for interferon-inducible p47 resistance GTPases Mol Cell 15 727 739 1:CAS:528:DC%2BD2cXnvFyhsrc%3D 10.1016/j.molcel.2004.07.017 15350217 (Pubitemid 39194903)
    • (2004) Molecular Cell , vol.15 , Issue.5 , pp. 727-739
    • Ghosh, A.1    Uthaiah, R.2    Howard, J.3    Herrmann, C.4    Wolf, E.5
  • 30
    • 0026552954 scopus 로고
    • The IRG-47 gene is IFN-gamma induced in B cells and encodes a protein with GTP-binding motifs
    • 1:CAS:528:DyaK3sXitFWjtro%3D 1578148
    • M Gilly R Wall 1992 The IRG-47 gene is IFN-gamma induced in B cells and encodes a protein with GTP-binding motifs J Immunol 148 3275 3281 1:CAS:528:DyaK3sXitFWjtro%3D 1578148
    • (1992) J Immunol , vol.148 , pp. 3275-3281
    • Gilly, M.1    Wall, R.2
  • 31
    • 10944253145 scopus 로고    scopus 로고
    • Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
    • DOI 10.1016/j.cell.2004.11.038, PII S0092867404011067
    • MG Gutierrez SS Master SB Singh GA Taylor MI Colombo, et al. 2004 Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages Cell 119 753 766 1:CAS:528:DC%2BD2MXmsFym 10.1016/j.cell.2004.11.038 15607973 (Pubitemid 40017683)
    • (2004) Cell , vol.119 , Issue.6 , pp. 753-766
    • Gutierrez, M.G.1    Master, S.S.2    Singh, S.B.3    Taylor, G.A.4    Colombo, M.I.5    Deretic, V.6
  • 32
    • 61649101227 scopus 로고    scopus 로고
    • Role of autophagy in the host defense against Toxoplasma gondii in astrocytes
    • 1:CAS:528:DC%2BD1MXovFeiu74%3D 10.4161/auto.5.2.7637 19139630
    • SK Halonen 2009 Role of autophagy in the host defense against Toxoplasma gondii in astrocytes Autophagy 5 268 269 1:CAS:528:DC%2BD1MXovFeiu74%3D 10.4161/auto.5.2.7637 19139630
    • (2009) Autophagy , vol.5 , pp. 268-269
    • Halonen, S.K.1
  • 33
    • 0034861021 scopus 로고    scopus 로고
    • Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP
    • DOI 10.1128/IAI.69.9.5573-5576.2001
    • SK Halonen GA Taylor LM Weiss 2001 Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP Infect Immun 69 5573 5576 1:CAS:528:DC%2BD3MXmsVars70%3D 10.1128/IAI.69.9.5573-5576.2001 11500431 (Pubitemid 32786493)
    • (2001) Infection and Immunity , vol.69 , Issue.9 , pp. 5573-5576
    • Halonen, S.K.1    Taylor, G.A.2    Weiss, L.M.3
  • 34
    • 38449116497 scopus 로고    scopus 로고
    • Impaired macrophage function underscores susceptibility to Salmonella in mice lacking Irgm1 (LRG-47)
    • 1:CAS:528:DC%2BD2sXht1Crs73P 17982087
    • SC Henry X Daniell M Indaram JF Whitesides GD Sempowski, et al. 2007 Impaired macrophage function underscores susceptibility to Salmonella in mice lacking Irgm1 (LRG-47) J Immunol 179 6963 6972 1:CAS:528:DC%2BD2sXht1Crs73P 17982087
    • (2007) J Immunol , vol.179 , pp. 6963-6972
    • Henry, S.C.1    Daniell, X.2    Indaram, M.3    Whitesides, J.F.4    Sempowski, G.D.5
  • 35
    • 65549154275 scopus 로고    scopus 로고
    • Balance of Irgm protein activities determines IFN-{gamma}-induced host defense
    • 1:CAS:528:DC%2BD1MXlvVCks7k%3D 10.1189/jlb.1008599 19176402
    • SC Henry XG Daniell AR Burroughs M Indaram DN Howell, et al. 2009 Balance of Irgm protein activities determines IFN-{gamma}-induced host defense J Leukoc Biol 85 877 885 1:CAS:528:DC%2BD1MXlvVCks7k%3D 10.1189/jlb.1008599 19176402
    • (2009) J Leukoc Biol , vol.85 , pp. 877-885
    • Henry, S.C.1    Daniell, X.G.2    Burroughs, A.R.3    Indaram, M.4    Howell, D.N.5
  • 36
    • 76149089546 scopus 로고    scopus 로고
    • Regulation of macrophage motility by Irgm1
    • 1:CAS:528:DC%2BC3cXhsFeisr4%3D 10.1189/jlb.0509299 19920210
    • SC Henry M Traver X Daniell M Indaram T Oliver, et al. 2010 Regulation of macrophage motility by Irgm1 J Leukoc Biol 87 2 333 343 1:CAS:528: DC%2BC3cXhsFeisr4%3D 10.1189/jlb.0509299 19920210
    • (2010) J Leukoc Biol , vol.87 , Issue.2 , pp. 333-343
    • Henry, S.C.1    Traver, M.2    Daniell, X.3    Indaram, M.4    Oliver, T.5
  • 37
    • 0028886480 scopus 로고
    • Toxoplasma gondii comprises three clonal lineages: Correlation of parasite genotype with human disease
    • 1:STN:280:DyaK28%2FotlGjsA%3D%3D 7594717
    • DK Howe LD Sibley 1995 Toxoplasma gondii comprises three clonal lineages: correlation of parasite genotype with human disease J Infect Dis 172 1561 1566 1:STN:280:DyaK28%2FotlGjsA%3D%3D 7594717
    • (1995) J Infect Dis , vol.172 , pp. 1561-1566
    • Howe, D.K.1    Sibley, L.D.2
  • 38
    • 77957687715 scopus 로고    scopus 로고
    • The mouse resistance protein Irgm1 (LRG-47): A regulator or an effector of pathogen defense?
    • 10.1371/journal.ppat.1001008 20664789
    • JP Hunn JC Howard 2010 The mouse resistance protein Irgm1 (LRG-47): A regulator or an effector of pathogen defense? PLoS Pathog 6 e1001008 10.1371/journal.ppat.1001008 20664789
    • (2010) PLoS Pathog , vol.6 , pp. 1001008
    • Hunn, J.P.1    Howard, J.C.2
  • 39
    • 53549109432 scopus 로고    scopus 로고
    • Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii
    • 1:CAS:528:DC%2BD1cXht1SlsLbL 10.1038/emboj.2008.176 18772884
    • JP Hunn S Koenen-Waisman N Papic N Schroeder N Pawlowski, et al. 2008 Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii EMBO J 27 2495 2509 1:CAS:528:DC%2BD1cXht1SlsLbL 10.1038/emboj.2008.176 18772884
    • (2008) EMBO J , vol.27 , pp. 2495-2509
    • Hunn, J.P.1    Koenen-Waisman, S.2    Papic, N.3    Schroeder, N.4    Pawlowski, N.5
  • 40
    • 70349672696 scopus 로고    scopus 로고
    • Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains
    • 10.1371/journal.ppat.1000577 19750224
    • CD Intemann T Thye S Niemann EN Browne M Amanua Chinbuah, et al. 2009 Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains PLoS Pathog 5 e1000577 10.1371/journal.ppat.1000577 19750224
    • (2009) PLoS Pathog , vol.5 , pp. 1000577
    • Intemann, C.D.1    Thye, T.2    Niemann, S.3    Browne, E.N.4    Amanua Chinbuah, M.5
  • 41
    • 0026691182 scopus 로고
    • The rapid generation of mutation data matrices from protein sequences
    • 1:CAS:528:DyaK38Xlt1Okt7w%3D 1633570
    • DT Jones WR Taylor JM Thornton 1992 The rapid generation of mutation data matrices from protein sequences Comput Appl Biosci 8 275 282 1:CAS:528:DyaK38Xlt1Okt7w%3D 1633570
    • (1992) Comput Appl Biosci , vol.8 , pp. 275-282
    • Jones, D.T.1    Taylor, W.R.2    Thornton, J.M.3
  • 42
    • 77954430293 scopus 로고    scopus 로고
    • Coordinated loading of IRG resistance GTPases onto the Toxoplasma gondii parasitophorous vacuole
    • 1:CAS:528:DC%2BC3cXotlKisbg%3D 10.1111/j.1462-5822.2010.01443.x 20109161
    • A Khaminets JP Hunn S Konen-Waisman YO Zhao D Preukschat, et al. 2010 Coordinated loading of IRG resistance GTPases onto the Toxoplasma gondii parasitophorous vacuole Cell Microbiol 12 7 939 961 1:CAS:528: DC%2BC3cXotlKisbg%3D 10.1111/j.1462-5822.2010.01443.x 20109161
    • (2010) Cell Microbiol , vol.12 , Issue.7 , pp. 939-961
    • Khaminets, A.1    Hunn, J.P.2    Konen-Waisman, S.3    Zhao, Y.O.4    Preukschat, D.5
  • 44
    • 62149118305 scopus 로고    scopus 로고
    • Selection at a single locus leads to widespread expansion of Toxoplasma gondii lineages that are virulent in mice
    • 10.1371/journal.pgen.1000404 19266027
    • A Khan S Taylor JW Ajioka BM Rosenthal LD Sibley 2009 Selection at a single locus leads to widespread expansion of Toxoplasma gondii lineages that are virulent in mice PLoS Genet 5 e1000404 10.1371/journal.pgen.1000404 19266027
    • (2009) PLoS Genet , vol.5 , pp. 1000404
    • Khan, A.1    Taylor, S.2    Ajioka, J.W.3    Rosenthal, B.M.4    Sibley, L.D.5
  • 46
    • 36749068951 scopus 로고    scopus 로고
    • Cell-autonomous immunity to Toxoplasma gondii in mouse and man
    • DOI 10.1016/j.micinf.2007.09.005, PII S1286457907002857, Forum on Cell-Autonomous Imunity
    • S Konen-Waisman JC Howard 2007 Cell-autonomous immunity to Toxoplasma gondii in mouse and man Microbes Infect 9 1652 1661 10.1016/j.micinf.2007.09.005 18024121 (Pubitemid 350217084)
    • (2007) Microbes and Infection , vol.9 , Issue.14-15 , pp. 1652-1661
    • Konen-Waisman, S.1    Howard, J.C.2
  • 47
    • 0028929928 scopus 로고
    • Cloning and characterization of a novel cDNA that is IFN-gamma-induced in mouse peritoneal macrophages and encodes a putative GTP-binding protein
    • 1:CAS:528:DyaK2MXktlOlu74%3D 7884320
    • WP Lafuse D Brown L Castle BS Zwilling 1995 Cloning and characterization of a novel cDNA that is IFN-gamma-induced in mouse peritoneal macrophages and encodes a putative GTP-binding protein J Leukoc Biol 57 477 483 1:CAS:528:DyaK2MXktlOlu74%3D 7884320
    • (1995) J Leukoc Biol , vol.57 , pp. 477-483
    • Lafuse, W.P.1    Brown, D.2    Castle, L.3    Zwilling, B.S.4
  • 48
    • 67649376348 scopus 로고    scopus 로고
    • The evolutionarily dynamic IFN-inducible GTPase proteins play conserved immune functions in vertebrates and cephalochordates
    • 1:CAS:528:DC%2BD1MXntlGjur0%3D 10.1093/molbev/msp074 19369598
    • G Li J Zhang Y Sun H Wang Y Wang 2009 The evolutionarily dynamic IFN-inducible GTPase proteins play conserved immune functions in vertebrates and cephalochordates Mol Biol Evol 26 1619 1630 1:CAS:528:DC%2BD1MXntlGjur0%3D 10.1093/molbev/msp074 19369598
    • (2009) Mol Biol Evol , vol.26 , pp. 1619-1630
    • Li, G.1    Zhang, J.2    Sun, Y.3    Wang, H.4    Wang, Y.5
  • 49
    • 33748444233 scopus 로고    scopus 로고
    • Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages
    • 1:CAS:528:DC%2BD28XptlSgs78%3D 10.1084/jem.20061318 16940170
    • YM Ling MH Shaw C Ayala I Coppens GA Taylor, et al. 2006 Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages J Exp Med 203 2063 2071 1:CAS:528: DC%2BD28XptlSgs78%3D 10.1084/jem.20061318 16940170
    • (2006) J Exp Med , vol.203 , pp. 2063-2071
    • Ling, Y.M.1    Shaw, M.H.2    Ayala, C.3    Coppens, I.4    Taylor, G.A.5
  • 50
    • 0142240338 scopus 로고    scopus 로고
    • Immune control of tuberculosis by IFN-γ-inducible LRG-47
    • DOI 10.1126/science.1088063
    • JD MacMicking GA Taylor JD McKinney 2003 Immune control of tuberculosis by IFN-gamma-inducible LRG-47 Science 302 654 659 1:CAS:528:DC%2BD3sXotlWqtL8%3D 10.1126/science.1088063 14576437 (Pubitemid 37310923)
    • (2003) Science , vol.302 , Issue.5645 , pp. 654-659
    • MacMicking, J.D.1    Taylor, G.A.2    McKinney, J.D.3
  • 51
    • 4043065683 scopus 로고    scopus 로고
    • Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: Retargeting to plasma membrane induced by phagocytosis
    • S Martens K Sabel R Lange R Uthaiah E Wolf, et al. 2004 Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis J Immunol 173 2594 2606 1:CAS:528:DC%2BD2cXmt1Olurw%3D 15294976 (Pubitemid 39063119)
    • (2004) Journal of Immunology , vol.173 , Issue.4 , pp. 2594-2606
    • Martens, S.1    Sabel, K.2    Lange, R.3    Uthaiah, R.4    Wolf, E.5    Howard, J.C.6
  • 52
    • 49649126253 scopus 로고    scopus 로고
    • Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases
    • 10.1371/journal.ppat.0010024 16304607
    • S Martens I Parvanova J Zerrahn G Griffiths G Schell, et al. 2005 Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases PLoS Pathog 1 e24 10.1371/journal.ppat.0010024 16304607
    • (2005) PLoS Pathog , vol.1 , pp. 24
    • Martens, S.1    Parvanova, I.2    Zerrahn, J.3    Griffiths, G.4    Schell, G.5
  • 53
    • 50449091647 scopus 로고    scopus 로고
    • Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
    • 1:CAS:528:DC%2BD1cXhtVGgtrfK 10.1038/ng.215 19165925
    • SA McCarroll A Huett P Kuballa SD Chilewski A Landry, et al. 2008 Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease Nat Genet 40 1107 1112 1:CAS:528:DC%2BD1cXhtVGgtrfK 10.1038/ng.215 19165925
    • (2008) Nat Genet , vol.40 , pp. 1107-1112
    • McCarroll, S.A.1    Huett, A.2    Kuballa, P.3    Chilewski, S.D.4    Landry, A.5
  • 54
    • 55849126156 scopus 로고    scopus 로고
    • The gamma interferon (IFN-gamma)-inducible GTP-binding protein IGTP is necessary for toxoplasma vacuolar disruption and induces parasite egression in IFN-gamma-stimulated astrocytes
    • 1:CAS:528:DC%2BD1cXhtlajtrvL 10.1128/IAI.01288-07 18765738
    • T Melzer A Duffy LM Weiss SK Halonen 2008 The gamma interferon (IFN-gamma)-inducible GTP-binding protein IGTP is necessary for toxoplasma vacuolar disruption and induces parasite egression in IFN-gamma-stimulated astrocytes Infect Immun 76 4883 4894 1:CAS:528:DC%2BD1cXhtlajtrvL 10.1128/IAI.01288-07 18765738
    • (2008) Infect Immun , vol.76 , pp. 4883-4894
    • Melzer, T.1    Duffy, A.2    Weiss, L.M.3    Halonen, S.K.4
  • 55
    • 34548644595 scopus 로고    scopus 로고
    • The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydia psittaci infection
    • 1:CAS:528:DC%2BD2sXnvVynu7Y%3D 17641048
    • I Miyairi VR Tatireddigari OS Mahdi LA Rose RJ Belland, et al. 2007 The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydia psittaci infection J Immunol 179 1814 1824 1:CAS:528: DC%2BD2sXnvVynu7Y%3D 17641048
    • (2007) J Immunol , vol.179 , pp. 1814-1824
    • Miyairi, I.1    Tatireddigari, V.R.2    Mahdi, O.S.3    Rose, L.A.4    Belland, R.J.5
  • 57
    • 65249123215 scopus 로고    scopus 로고
    • Toxoplasma-induced autophagy: A window into nutritional futile cycles in mammalian cells?
    • 1:CAS:528:DC%2BD1MXnvVyrs78%3D 10.4161/auto.5.3.7807 19305153
    • A Orlofsky 2009 Toxoplasma-induced autophagy: A window into nutritional futile cycles in mammalian cells? Autophagy 5 3 404 406 1:CAS:528: DC%2BD1MXnvVyrs78%3D 10.4161/auto.5.3.7807 19305153
    • (2009) Autophagy , vol.5 , Issue.3 , pp. 404-406
    • Orlofsky, A.1
  • 58
    • 57649115443 scopus 로고    scopus 로고
    • Inactive and active states of the interferon-inducible resistance GTPase, Irga6, in vivo
    • 1:CAS:528:DC%2BD1cXhtlCjsbfM 10.1074/jbc.M804846200 18784077
    • N Papic JP Hunn N Pawlowski J Zerrahn JC Howard 2008 Inactive and active states of the interferon-inducible resistance GTPase, Irga6, in vivo J Biol Chem 283 32143 32151 1:CAS:528:DC%2BD1cXhtlCjsbfM 10.1074/jbc.M804846200 18784077
    • (2008) J Biol Chem , vol.283 , pp. 32143-32151
    • Papic, N.1    Hunn, J.P.2    Pawlowski, N.3    Zerrahn, J.4    Howard, J.C.5
  • 61
    • 0742288598 scopus 로고    scopus 로고
    • The dynamin superfamily: Universal membrane tubulation and fission molecules?
    • DOI 10.1038/nrm1313
    • GJ Praefcke HT McMahon 2004 The dynamin superfamily: universal membrane tubulation and fission molecules? Nat Rev Mol Cell Biol 5 133 147 1:CAS:528:DC%2BD2cXnsFOjsg%3D%3D 10.1038/nrm1313 15040446 (Pubitemid 38160256)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.2 , pp. 133-147
    • Praefcke, G.J.K.1    McMahon, H.T.2
  • 62
    • 7044239234 scopus 로고    scopus 로고
    • Identification of residues in the human guanylate-binding protein 1 critical for nucleotide binding and cooperative GTP hydrolysis
    • DOI 10.1016/j.jmb.2004.09.026, PII S0022283604011684
    • GJ Praefcke S Kloep U Benscheid H Lilie B Prakash, et al. 2004 Identification of residues in the human guanylate-binding protein 1 critical for nucleotide binding and cooperative GTP hydrolysis J Mol Biol 344 257 269 1:CAS:528:DC%2BD2cXovVKktb4%3D 10.1016/j.jmb.2004.09.026 15504415 (Pubitemid 39422386)
    • (2004) Journal of Molecular Biology , vol.344 , Issue.1 , pp. 257-269
    • Praefcke, G.J.K.1    Kloep, S.2    Benscheid, U.3    Lilie, H.4    Prakash, B.5    Herrmann, C.6
  • 63
    • 0034598734 scopus 로고    scopus 로고
    • Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins
    • DOI 10.1038/35000617
    • B Prakash GJ Praefcke L Renault A Wittinghofer C Herrmann 2000 Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins Nature 403 567 571 1:CAS:528:DC%2BD3cXht1Wgt7Y%3D 10.1038/35000617 10676968 (Pubitemid 30082205)
    • (2000) Nature , vol.403 , Issue.6769 , pp. 567-571
    • Prakash, B.1    Praefcke, G.J.K.2    Renault, L.3    Wittinghofer, A.4    Herrmann, C.5
  • 64
    • 57649238675 scopus 로고    scopus 로고
    • Real-time visualization of dynamin-catalyzed membrane fission and vesicle release
    • 1:CAS:528:DC%2BD1MXisFyisg%3D%3D 10.1016/j.cell.2008.11.020 19084268
    • TJ Pucadyil SL Schmid 2008 Real-time visualization of dynamin-catalyzed membrane fission and vesicle release Cell 135 1263 1275 1:CAS:528: DC%2BD1MXisFyisg%3D%3D 10.1016/j.cell.2008.11.020 19084268
    • (2008) Cell , vol.135 , pp. 1263-1275
    • Pucadyil, T.J.1    Schmid, S.L.2
  • 66
    • 53849092760 scopus 로고    scopus 로고
    • Population structure of Toxoplasma gondii: Clonal expansion driven by infrequent recombination and selective sweeps
    • 1:CAS:528:DC%2BD1cXht1Gls73I 10.1146/annurev.micro.62.081307.162925 18544039
    • LD Sibley JW Ajioka 2008 Population structure of Toxoplasma gondii: clonal expansion driven by infrequent recombination and selective sweeps Annu Rev Microbiol 62 329 351 1:CAS:528:DC%2BD1cXht1Gls73I 10.1146/annurev.micro.62. 081307.162925 18544039
    • (2008) Annu Rev Microbiol , vol.62 , pp. 329-351
    • Sibley, L.D.1    Ajioka, J.W.2
  • 68
    • 33748506089 scopus 로고    scopus 로고
    • Human IRGM induces autophagy to eliminate intracellular mycobacteria
    • DOI 10.1126/science.1129577
    • SB Singh AS Davis GA Taylor V Deretic 2006 Human IRGM induces autophagy to eliminate intracellular mycobacteria Science 313 1438 1441 1:CAS:528:DC%2BD28XptFWju7o%3D 10.1126/science.1129577 16888103 (Pubitemid 44360272)
    • (2006) Science , vol.313 , Issue.5792 , pp. 1438-1441
    • Singh, S.B.1    Davis, A.S.2    Taylor, G.A.3    Deretic, V.4
  • 69
    • 0028837679 scopus 로고
    • Identification of an endotoxin and IFN-inducible cDNA: Possible identification of a novel protein family
    • 1:CAS:528:DyaK2MXos1anu7k%3D 7561525
    • JM Sorace RJ Johnson DL Howard BE Drysdale 1995 Identification of an endotoxin and IFN-inducible cDNA: possible identification of a novel protein family J Leukoc Biol 58 477 484 1:CAS:528:DyaK2MXos1anu7k%3D 7561525
    • (1995) J Leukoc Biol , vol.58 , pp. 477-484
    • Sorace, J.M.1    Johnson, R.J.2    Howard, D.L.3    Drysdale, B.E.4
  • 70
    • 0032511190 scopus 로고    scopus 로고
    • Dynamin undergoes a GTP-dependent conformational change causing vesiculation
    • DOI 10.1016/S0092-8674(00)81207-6
    • SM Sweitzer JE Hinshaw 1998 Dynamin undergoes a GTP-dependent conformational change causing vesiculation Cell 93 1021 1029 1:CAS:528:DyaK1cXjvFKqsLc%3D 10.1016/S0092-8674(00)81207-6 9635431 (Pubitemid 28280795)
    • (1998) Cell , vol.93 , Issue.6 , pp. 1021-1029
    • Sweitzer, S.M.1    Hinshaw, J.E.2
  • 71
    • 34047256441 scopus 로고    scopus 로고
    • IRG proteins: Key mediators of interferon-regulated host resistance to intracellular pathogens
    • DOI 10.1111/j.1462-5822.2007.00916.x
    • GA Taylor 2007 IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens Cell Microbiol 9 1099 1107 1:CAS:528:DC%2BD2sXkvFSlsrY%3D 10.1111/j.1462-5822.2007.00916.x 17359233 (Pubitemid 46547130)
    • (2007) Cellular Microbiology , vol.9 , Issue.5 , pp. 1099-1107
    • Taylor, G.A.1
  • 72
    • 0029832205 scopus 로고    scopus 로고
    • Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon γ
    • DOI 10.1074/jbc.271.34.20399
    • GA Taylor M Jeffers DA Largaespada NA Jenkins NG Copeland, et al. 1996 Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma J Biol Chem 271 20399 20405 1:CAS:528:DyaK28Xlt1ygtbY%3D 10.1074/jbc.271.34.20399 8702776 (Pubitemid 26281808)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.34 , pp. 20399-20405
    • Taylor, G.A.1    Jeffers, M.2    Largaespada, D.A.3    Jenkins, N.A.4    Copeland, N.G.5    Vande Woude, G.F.6
  • 75
    • 1142298755 scopus 로고    scopus 로고
    • p47 GTPases: Regulators of immunity to intracellular pathogens
    • GA Taylor CG Feng A Sher 2004 p47 GTPases: regulators of immunity to intracellular pathogens Nat Rev Immunol 4 100 109 1:CAS:528:DC%2BD2cXhsVKqsro%3D 10.1038/nri1270 15040583 (Pubitemid 38209204)
    • (2004) Nature Reviews Immunology , vol.4 , Issue.2 , pp. 100-109
    • Taylor, G.A.1    Feng, C.G.2    Sher, A.3
  • 77
    • 36749064729 scopus 로고    scopus 로고
    • Control of IFN-γ-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases)
    • DOI 10.1016/j.micinf.2007.09.004, PII S1286457907002845, Forum on Cell-Autonomous Imunity
    • GA Taylor CG Feng A Sher 2007 Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases) Microbes Infect 9 1644 1651 1:CAS:528:DC%2BD2sXhsVCjt7nN 10.1016/j.micinf.2007. 09.004 18023232 (Pubitemid 350225741)
    • (2007) Microbes and Infection , vol.9 , Issue.14-15 , pp. 1644-1651
    • Taylor, G.A.1    Feng, C.G.2    Sher, A.3
  • 78
    • 0028036711 scopus 로고
    • Activation of dynamin GTPase is a result of positive cooperativity
    • PL Tuma CA Collins 1994 Activation of dynamin GTPase is a result of positive cooperativity J Biol Chem 269 30842 30847 1:CAS:528:DyaK2cXmslGisbk%3D 7983015 (Pubitemid 24377567)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.49 , pp. 30842-30847
    • Tuma, P.L.1    Collins, C.A.2
  • 79
    • 0043033168 scopus 로고    scopus 로고
    • IIGP1, an interferon-γ-inducible 47-kDa GTPase of the mouse, showing cooperative enzymatic activity and GTP-dependent multimerization
    • DOI 10.1074/jbc.M211973200
    • RC Uthaiah GJ Praefcke JC Howard C Herrmann 2003 IIGP1, an interferon-gamma-inducible 47-kDa GTPase of the mouse, showing cooperative enzymatic activity and GTP-dependent multimerization J Biol Chem 278 29336 29343 1:CAS:528:DC%2BD3sXlsl2mt7c%3D 10.1074/jbc.M211973200 12732635 (Pubitemid 36935850)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.31 , pp. 29336-29343
    • Uthaiah, R.C.1    Praefcke, G.J.K.2    Howard, J.C.3    Herrmann, C.4
  • 80
    • 59449103030 scopus 로고    scopus 로고
    • Host cell autophagy is induced by Toxoplasma gondii and contributes to parasite growth
    • 1:CAS:528:DC%2BD1MXjtFOiuw%3D%3D 10.1074/jbc.M807890200 19028680
    • Y Wang LM Weiss A Orlofsky 2009 Host cell autophagy is induced by Toxoplasma gondii and contributes to parasite growth J Biol Chem 284 1694 1701 1:CAS:528:DC%2BD1MXjtFOiuw%3D%3D 10.1074/jbc.M807890200 19028680
    • (2009) J Biol Chem , vol.284 , pp. 1694-1701
    • Wang, Y.1    Weiss, L.M.2    Orlofsky, A.3
  • 81
    • 0029787352 scopus 로고    scopus 로고
    • Dynamin self-assembly stimulates its GTPase activity
    • DOI 10.1074/jbc.271.37.22310
    • DE Warnock JE Hinshaw SL Schmid 1996 Dynamin self-assembly stimulates its GTPase activity J Biol Chem 271 22310 22314 1:CAS:528:DyaK28XlslaitL4%3D 10.1074/jbc.271.37.22310 8798389 (Pubitemid 26304660)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.37 , pp. 22310-22314
    • Warnock, D.E.1    Hinshaw, J.E.2    Schmid, S.L.3
  • 82
    • 69449108432 scopus 로고    scopus 로고
    • A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1), in mouse liver
    • 10.1371/journal.pone.0006787 20368812
    • J Zeng IA Parvanova JC Howard 2009 A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1), in mouse liver PLoS One 4 e6787 10.1371/journal.pone.0006787 20368812
    • (2009) PLoS One , vol.4 , pp. 6787
    • Zeng, J.1    Parvanova, I.A.2    Howard, J.C.3
  • 83
    • 55249109400 scopus 로고    scopus 로고
    • Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens
    • 1:CAS:528:DC%2BD1cXhsVWku7fO 10.1016/j.chom.2008.10.003 18996346
    • Z Zhao B Fux M Goodwin IR Dunay D Strong, et al. 2008 Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens Cell Host Microbe 4 458 469 1:CAS:528:DC%2BD1cXhsVWku7fO 10.1016/j.chom.2008.10.003 18996346
    • (2008) Cell Host Microbe , vol.4 , pp. 458-469
    • Zhao, Z.1    Fux, B.2    Goodwin, M.3    Dunay, I.R.4    Strong, D.5
  • 84
    • 65449163019 scopus 로고    scopus 로고
    • Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages
    • 1:CAS:528:DC%2BD1MXis12hsL8%3D 10.4049/jimmunol.0804190 19265156
    • Y Zhao DJ Ferguson DC Wilson JC Howard LD Sibley, et al. 2009 Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages J Immunol 182 3775 3781 1:CAS:528:DC%2BD1MXis12hsL8%3D 10.4049/jimmunol.0804190 19265156
    • (2009) J Immunol , vol.182 , pp. 3775-3781
    • Zhao, Y.1    Ferguson, D.J.2    Wilson, D.C.3    Howard, J.C.4    Sibley, L.D.5
  • 85
    • 61449117883 scopus 로고    scopus 로고
    • Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death
    • 10.1371/journal.ppat.1000288 19197351
    • YO Zhao A Khaminets JP Hunn JC Howard 2009 Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death PLoS Pathog 5 e1000288 10.1371/journal.ppat.1000288 19197351
    • (2009) PLoS Pathog , vol.5 , pp. 1000288
    • Zhao, Y.O.1    Khaminets, A.2    Hunn, J.P.3    Howard, J.C.4
  • 86
    • 65549141857 scopus 로고    scopus 로고
    • Toxoplasma gondii and the Immunity-Related GTPase (IRG) resistance system in mice: A review
    • 1:CAS:528:DC%2BD1MXotFOlu7s%3D 10.1590/S0074-02762009000200016 19430648
    • YO Zhao C Rohde JT Lilue S Konen-Waisman A Khaminets, et al. 2009 Toxoplasma gondii and the Immunity-Related GTPase (IRG) resistance system in mice: a review Mem Inst Oswaldo Cruz 104 234 240 1:CAS:528:DC%2BD1MXotFOlu7s%3D 10.1590/S0074-02762009000200016 19430648
    • (2009) Mem Inst Oswaldo Cruz , vol.104 , pp. 234-240
    • Zhao, Y.O.1    Rohde, C.2    Lilue, J.T.3    Konen-Waisman, S.4    Khaminets, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.