-
1
-
-
84864290306
-
IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy
-
10.1371/journal.pone.0004588 19242543
-
MA Al-Zeer HM Al-Younes PR Braun J Zerrahn TF Meyer 2009 IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy PLoS One 4 e4588 10.1371/journal.pone.0004588 19242543
-
(2009)
PLoS One
, vol.4
, pp. 4588
-
-
Al-Zeer, M.A.1
Al-Younes, H.M.2
Braun, P.R.3
Zerrahn, J.4
Meyer, T.F.5
-
2
-
-
0017081605
-
Strain-dependent differences in murine susceptibility to toxoplasma
-
1:STN:280:DyaE287ovFektw%3D%3D 1270155
-
FG Araujo DM Williams FC Grumet JS Remington, et al. 1976 Strain-dependent differences in murine susceptibility to toxoplasma Infect Immun 13 5 1528 1530 1:STN:280:DyaE287ovFektw%3D%3D 1270155
-
(1976)
Infect Immun
, vol.13
, Issue.5
, pp. 1528-1530
-
-
Araujo, F.G.1
Williams, D.M.2
Grumet, F.C.3
Remington, J.S.4
-
3
-
-
57649215874
-
GTPase cycle of dynamin is coupled to membrane squeeze and release, leading to spontaneous fission
-
1:CAS:528:DC%2BD1MXisFyisw%3D%3D 10.1016/j.cell.2008.11.028 19084269
-
PV Bashkirov SA Akimov AI Evseev SL Schmid J Zimmerberg, et al. 2008 GTPase cycle of dynamin is coupled to membrane squeeze and release, leading to spontaneous fission Cell 135 1276 1286 1:CAS:528:DC%2BD1MXisFyisw%3D%3D 10.1016/j.cell.2008.11.028 19084269
-
(2008)
Cell
, vol.135
, pp. 1276-1286
-
-
Bashkirov, P.V.1
Akimov, S.A.2
Evseev, A.I.3
Schmid, S.L.4
Zimmerberg, J.5
-
4
-
-
33744509713
-
The interferon-inducible p47 (IRG) GTPases in vertebrates: Loss of the cell autonomous resistance mechanism in the human lineage
-
10.1186/gb-2005-6-11-r92 16277747
-
C Bekpen JP Hunn C Rohde I Parvanova L Guethlein, et al. 2005 The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage Genome Biol 6 R92 10.1186/gb-2005-6-11-r92 16277747
-
(2005)
Genome Biol
, vol.6
, pp. 92
-
-
Bekpen, C.1
Hunn, J.P.2
Rohde, C.3
Parvanova, I.4
Guethlein, L.5
-
6
-
-
33748995352
-
The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice
-
DOI 10.1073/pnas.0603338103
-
I Bernstein-Hanley J Coers ZR Balsara GA Taylor MN Starnbach, et al. 2006 The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice Proc Natl Acad Sci USA 103 14092 14097 1:CAS:528:DC%2BD28XhtVCmur%2FO 10.1073/pnas.0603338103 16959883 (Pubitemid 44452985)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.38
, pp. 14092-14097
-
-
Bernstein-Hanley, I.1
Coers, J.2
Balsara, Z.R.3
Taylor, G.A.4
Starnbach, M.N.5
Dietrich, W.F.6
-
7
-
-
53149101681
-
Correlation between self-association modes and GTPase activation of dynamin
-
DOI 10.1023/A:1021083211267
-
DD Binns B Barylko N Grichine MA Atkinson MK Helms, et al. 1999 Correlation between self-association modes and GTPase activation of dynamin J Protein Chem 18 277 290 1:CAS:528:DyaK1MXjvFyhsLs%3D 10.1023/A:1021083211267 10395446 (Pubitemid 29293201)
-
(1999)
Journal of Protein Chemistry
, vol.18
, Issue.3
, pp. 277-290
-
-
Binns, D.D.1
Barylko, B.2
Grichine, N.3
Atkinson, M.A.L.4
Helms, M.K.5
Jameson, D.M.6
Eccleston, J.F.7
Albanesi, J.P.8
-
8
-
-
0032534733
-
Two families of GTPases dominate the complex cellular response to IFN- γ
-
U Boehm L Guethlein T Klamp K Ozbek A Schaub, et al. 1998 Two families of GTPases dominate the complex cellular response to IFN-gamma J Immunol 161 6715 6723 1:CAS:528:DyaK1cXotFWqt74%3D 9862701 (Pubitemid 28562214)
-
(1998)
Journal of Immunology
, vol.161
, Issue.12
, pp. 6715-6723
-
-
Boehm, U.1
Guethlein, L.2
Klamp, T.3
Ozbek, K.4
Schaub, A.5
Futterer, A.6
Pfeffer, K.7
Howard, J.C.8
-
9
-
-
0027732538
-
Proteins regulating Ras and its relatives
-
DOI 10.1038/366643a0
-
MS Boguski F McCormick 1993 Proteins regulating Ras and its relatives Nature 366 643 654 1:CAS:528:DyaK2cXnt1SisQ%3D%3D 10.1038/366643a0 8259209 (Pubitemid 24036012)
-
(1993)
Nature
, vol.366
, Issue.6456
, pp. 643-654
-
-
Boguski, M.S.1
McCormick, F.2
-
10
-
-
0036342974
-
Population biology of Toxoplasma gondii and its relevance to human infection: Do different strains cause different disease?
-
10.1016/S1369-5274(02)00349-1 12160866
-
JC Boothroyd ME Grigg 2002 Population biology of Toxoplasma gondii and its relevance to human infection: do different strains cause different disease? Curr Opin Microbiol 5 438 442 10.1016/S1369-5274(02)00349-1 12160866
-
(2002)
Curr Opin Microbiol
, vol.5
, pp. 438-442
-
-
Boothroyd, J.C.1
Grigg, M.E.2
-
11
-
-
68649128145
-
A role for lipid bodies in the cross-presentation of phagocytosed antigens by MHC class i in dendritic cells
-
1:CAS:528:DC%2BD1MXhtFOgsL7J 10.1016/j.immuni.2009.06.022 19699172
-
L Bougneres J Helft S Tiwari P Vargas BH Chang, et al. 2009 A role for lipid bodies in the cross-presentation of phagocytosed antigens by MHC class I in dendritic cells Immunity 31 232 244 1:CAS:528:DC%2BD1MXhtFOgsL7J 10.1016/j.immuni.2009.06.022 19699172
-
(2009)
Immunity
, vol.31
, pp. 232-244
-
-
Bougneres, L.1
Helft, J.2
Tiwari, S.3
Vargas, P.4
Chang, B.H.5
-
12
-
-
33745913320
-
Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii
-
DOI 10.1073/pnas.0510319103
-
JP Boyle B Rajasekar JP Saeij JW Ajioka M Berriman, et al. 2006 Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii Proc Natl Acad Sci USA 103 10514 10519 1:CAS:528:DC%2BD28XnsVSjtro%3D 10.1073/pnas.0510319103 16801557 (Pubitemid 44051198)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.27
, pp. 10514-10519
-
-
Boyle, J.P.1
Rajasekar, B.2
Saeij, J.P.J.3
Ajioka, J.W.4
Berriman, M.5
Paulsen, I.6
Roos, D.S.7
Sibley, L.D.8
White, M.W.9
Boothroyd, J.C.10
-
13
-
-
19744378057
-
p47 GTPases regulate Toxoplasma gondii survival in activated macrophages
-
DOI 10.1128/IAI.73.6.3278-3286.2005
-
BA Butcher RI Greene SC Henry KL Annecharico JB Weinberg EY Denkers A Sher GA Taylor, et al. 2005 p47 GTPases regulate Toxoplasma gondii survival in activated macrophages Infect Immun 73 3278 3286 1:CAS:528:DC%2BD2MXkvFCgurk%3D 10.1128/IAI.73.6.3278-3286.2005 15908352 (Pubitemid 40745867)
-
(2005)
Infection and Immunity
, vol.73
, Issue.6
, pp. 3278-3286
-
-
Butcher, B.A.1
Greene, R.I.2
Henry, S.C.3
Annecharico, K.L.4
Weinberg, J.B.5
Denkers, E.Y.6
Sher, A.7
Taylor, G.A.8
-
14
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
1:CAS:528:DC%2BD1cXhtlKmtL%2FI 10.1038/nature07416 18849966
-
K Cadwell JY Liu SL Brown H Miyoshi J Loh, et al. 2008 A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells Nature 456 259 263 1:CAS:528:DC%2BD1cXhtlKmtL%2FI 10.1038/nature07416 18849966
-
(2008)
Nature
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
Miyoshi, H.4
Loh, J.5
-
15
-
-
0028835390
-
Isolation of a gene encoding a developmentally regulated T cell-specific protein with a guanine nucleotide triphosphate-binding motif
-
1:CAS:528:DyaK2MXjs1art78%3D 7836757
-
DA Carlow J Marth I Clark-Lewis HS Teh 1995 Isolation of a gene encoding a developmentally regulated T cell-specific protein with a guanine nucleotide triphosphate-binding motif J Immunol 154 1724 1734 1:CAS:528:DyaK2MXjs1art78%3D 7836757
-
(1995)
J Immunol
, vol.154
, pp. 1724-1734
-
-
Carlow, D.A.1
Marth, J.2
Clark-Lewis, I.3
Teh, H.S.4
-
16
-
-
39049191429
-
The rat Toxo1 locus controls the outcome of the toxoplasmic infection according to a mendelian mode
-
P Cavailles C Bisanz O Papapietro C Colacios V Sergent, et al. 2006 The rat Toxo1 locus controls the outcome of the toxoplasmic infection according to a mendelian mode Med Sci (Paris) 22 679 680
-
(2006)
Med Sci (Paris)
, vol.22
, pp. 679-680
-
-
Cavailles, P.1
Bisanz, C.2
Papapietro, O.3
Colacios, C.4
Sergent, V.5
-
17
-
-
77956482589
-
Identification of a novel IRGM promoter single nucleotide polymorphism associated with tuberculosis
-
1:CAS:528:DC%2BC3cXhtFGhtL7P 10.1016/j.cca.2010.06.009 20547146
-
N Che S Li T Gao Z Zhang Y Han, et al. 2010 Identification of a novel IRGM promoter single nucleotide polymorphism associated with tuberculosis Clin Chim Acta 411 21-22 1645 1649 1:CAS:528:DC%2BC3cXhtFGhtL7P 10.1016/j.cca.2010. 06.009 20547146
-
(2010)
Clin Chim Acta
, vol.411
, Issue.2122
, pp. 1645-1649
-
-
Che, N.1
Li, S.2
Gao, T.3
Zhang, Z.4
Han, Y.5
-
18
-
-
75949090239
-
IFN-inducible p47 GTPases display differential responses to Schistosoma japonicum acute infection
-
1:CAS:528:DC%2BC3cXht1Kktr8%3D 10.1038/cmi.2009.100 20029464
-
X Chen X Du M Zhang D Zhang M Ji, et al. 2010 IFN-inducible p47 GTPases display differential responses to Schistosoma japonicum acute infection Cell Mol Immunol 7 1 69 76 1:CAS:528:DC%2BC3cXht1Kktr8%3D 10.1038/cmi.2009.100 20029464
-
(2010)
Cell Mol Immunol
, vol.7
, Issue.1
, pp. 69-76
-
-
Chen, X.1
Du, X.2
Zhang, M.3
Zhang, D.4
Ji, M.5
-
19
-
-
44449088023
-
Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10
-
1:CAS:528:DC%2BD1cXkvVCjtrk%3D 18424746
-
J Coers I Bernstein-Hanley D Grotsky I Parvanova JC Howard, et al. 2008 Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10 J Immunol 180 6237 6245 1:CAS:528:DC%2BD1cXkvVCjtrk%3D 18424746
-
(2008)
J Immunol
, vol.180
, pp. 6237-6245
-
-
Coers, J.1
Bernstein-Hanley, I.2
Grotsky, D.3
Parvanova, I.4
Howard, J.C.5
-
20
-
-
0035898464
-
Inactivation of LRG-47 and IRG-47 reveals a family of interferon γ-inducible genes with essential, pathogen-specific roles in resistance to infection
-
DOI 10.1084/jem.194.2.181
-
CM Collazo GS Yap GD Sempowski KC Lusby L Tessarollo, et al. 2001 Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection J Exp Med 194 181 188 1:CAS:528:DC%2BD3MXlsVCksbY%3D 10.1084/jem.194.2.181 11457893 (Pubitemid 32673351)
-
(2001)
Journal of Experimental Medicine
, vol.194
, Issue.2
, pp. 181-187
-
-
Collazo, C.M.1
Yap, G.S.2
Sempowski, G.D.3
Lusby, K.C.4
Tessarollo, L.5
Vande Woude, G.F.6
Sher, A.7
Taylor, G.A.8
-
21
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
DOI 10.1038/nature05911, PII NATURE05911
-
WTCC Consortium 2007 Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls Nature 447 661 678 10.1038/nature05911 (Pubitemid 46889737)
-
(2007)
Nature
, vol.447
, Issue.7145
, pp. 661-678
-
-
Burton, P.R.1
Clayton, D.G.2
Cardon, L.R.3
Craddock, N.4
Deloukas, P.5
Duncanson, A.6
Kwiatkowski, D.P.7
McCarthy, M.I.8
Ouwehand, W.H.9
Samani, N.J.10
Todd, J.A.11
Donnelly, P.12
Barrett, J.C.13
Davison, D.14
Easton, D.15
Evans, D.16
Leung, H.-T.17
Marchini, J.L.18
Morris, A.P.19
Spencer, C.C.A.20
Tobin, M.D.21
more..
-
22
-
-
77950405093
-
Genome-wide association study of CNVs in 16, 000 cases of eight common diseases and 3, 000 shared controls
-
1:CAS:528:DC%2BC3cXktVygsb4%3D 10.1038/nature08979 20360734
-
N Craddock ME Hurles N Cardin RD Pearson V Plagnol, et al. 2010 Genome-wide association study of CNVs in 16, 000 cases of eight common diseases and 3, 000 shared controls Nature 464 713 720 1:CAS:528:DC%2BC3cXktVygsb4%3D 10.1038/nature08979 20360734
-
(2010)
Nature
, vol.464
, pp. 713-720
-
-
Craddock, N.1
Hurles, M.E.2
Cardin, N.3
Pearson, R.D.4
Plagnol, V.5
-
23
-
-
38849193453
-
Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense
-
1:CAS:528:DC%2BD2sXhtlajt7jM 18025219
-
D Degrandi C Konermann C Beuter-Gunia A Kresse J Wurthner, et al. 2007 Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense J Immunol 179 7729 7740 1:CAS:528:DC%2BD2sXhtlajt7jM 18025219
-
(2007)
J Immunol
, vol.179
, pp. 7729-7740
-
-
Degrandi, D.1
Konermann, C.2
Beuter-Gunia, C.3
Kresse, A.4
Wurthner, J.5
-
24
-
-
0346998051
-
Absence of Interferon-γ-Inducible Gene IGTP Does Not Significantly Alter the Development of Chagasic Cardiomyopathy in Mice Infected with Trypanosoma cruzi (Brazil Strain)
-
DOI 10.1645/GE-3185RN
-
AP de Souza B Tang HB Tanowitz SM Factor V Shtutin J Shirani GA Taylor LM Weiss LA Jelicks 2003 Absence of interferon-gamma-inducible gene IGTP does not significantly alter the development of chagasic cardiomyopathy in mice infected with Trypanosoma cruzi (Brazil strain) J Parasitol 89 1237 1239 1:STN:280:DC%2BD2c%2FktVKlug%3D%3D 10.1645/GE-3185RN 14740917 (Pubitemid 38049816)
-
(2003)
Journal of Parasitology
, vol.89
, Issue.6
, pp. 1237-1239
-
-
De Souza, A.P.1
Tang, B.2
Tanowitz, H.B.3
Factor, S.M.4
Shtutin, V.5
Shirani, J.6
Taylor, G.A.7
Weiss, L.M.8
Jelicks, L.A.9
-
25
-
-
1142292747
-
Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia
-
CG Feng CM Collazo-Custodio M Eckhaus S Hieny Y Belkaid, et al. 2004 Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia J Immunol 172 1163 1168 1:CAS:528:DC%2BD2cXnvVSr 14707092 (Pubitemid 38113777)
-
(2004)
Journal of Immunology
, vol.172
, Issue.2
, pp. 1163-1168
-
-
Feng, C.G.1
Collazo-Custodio, C.M.2
Eckhaus, M.3
Hieny, S.4
Belkaid, Y.5
Elkins, K.6
Jankovic, D.7
Taylor, G.A.8
Sher, A.9
-
26
-
-
37549048915
-
The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation
-
1:CAS:528:DC%2BD1cXhtFOlt7c%3D 10.1016/j.stem.2007.10.007 18371424
-
CG Feng DC Weksberg GA Taylor A Sher MA Goodell 2008 The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation Cell Stem Cell 2 83 89 1:CAS:528:DC%2BD1cXhtFOlt7c%3D 10.1016/j.stem.2007.10.007 18371424
-
(2008)
Cell Stem Cell
, vol.2
, pp. 83-89
-
-
Feng, C.G.1
Weksberg, D.C.2
Taylor, G.A.3
Sher, A.4
Goodell, M.A.5
-
27
-
-
54549089752
-
The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death
-
1:CAS:528:DC%2BD1cXht1KrtbjN 10.1038/ni.1653 18806793
-
CG Feng L Zheng D Jankovic A Bafica JL Cannons, et al. 2008 The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death Nat Immunol 9 1279 1287 1:CAS:528:DC%2BD1cXht1KrtbjN 10.1038/ni.1653 18806793
-
(2008)
Nat Immunol
, vol.9
, pp. 1279-1287
-
-
Feng, C.G.1
Zheng, L.2
Jankovic, D.3
Bafica, A.4
Cannons, J.L.5
-
28
-
-
77953028450
-
Structural basis of oligomerization in the stalk region of dynamin-like MxA
-
1:CAS:528:DC%2BC3cXltlWmsr4%3D 10.1038/nature08972 20428112
-
S Gao A von der Malsburg S Paeschke J Behlke O Haller, et al. 2010 Structural basis of oligomerization in the stalk region of dynamin-like MxA Nature 465 502 506 1:CAS:528:DC%2BC3cXltlWmsr4%3D 10.1038/nature08972 20428112
-
(2010)
Nature
, vol.465
, pp. 502-506
-
-
Gao, S.1
Von Der Malsburg, A.2
Paeschke, S.3
Behlke, J.4
Haller, O.5
-
29
-
-
4444322564
-
Crystal structure of IIGP1: A paradigm for interferon-inducible p47 resistance GTPases
-
DOI 10.1016/j.molcel.2004.07.017, PII S1097276504004393
-
A Ghosh R Uthaiah J Howard C Herrmann E Wolf 2004 Crystal structure of IIGP1: a paradigm for interferon-inducible p47 resistance GTPases Mol Cell 15 727 739 1:CAS:528:DC%2BD2cXnvFyhsrc%3D 10.1016/j.molcel.2004.07.017 15350217 (Pubitemid 39194903)
-
(2004)
Molecular Cell
, vol.15
, Issue.5
, pp. 727-739
-
-
Ghosh, A.1
Uthaiah, R.2
Howard, J.3
Herrmann, C.4
Wolf, E.5
-
30
-
-
0026552954
-
The IRG-47 gene is IFN-gamma induced in B cells and encodes a protein with GTP-binding motifs
-
1:CAS:528:DyaK3sXitFWjtro%3D 1578148
-
M Gilly R Wall 1992 The IRG-47 gene is IFN-gamma induced in B cells and encodes a protein with GTP-binding motifs J Immunol 148 3275 3281 1:CAS:528:DyaK3sXitFWjtro%3D 1578148
-
(1992)
J Immunol
, vol.148
, pp. 3275-3281
-
-
Gilly, M.1
Wall, R.2
-
31
-
-
10944253145
-
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
-
DOI 10.1016/j.cell.2004.11.038, PII S0092867404011067
-
MG Gutierrez SS Master SB Singh GA Taylor MI Colombo, et al. 2004 Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages Cell 119 753 766 1:CAS:528:DC%2BD2MXmsFym 10.1016/j.cell.2004.11.038 15607973 (Pubitemid 40017683)
-
(2004)
Cell
, vol.119
, Issue.6
, pp. 753-766
-
-
Gutierrez, M.G.1
Master, S.S.2
Singh, S.B.3
Taylor, G.A.4
Colombo, M.I.5
Deretic, V.6
-
32
-
-
61649101227
-
Role of autophagy in the host defense against Toxoplasma gondii in astrocytes
-
1:CAS:528:DC%2BD1MXovFeiu74%3D 10.4161/auto.5.2.7637 19139630
-
SK Halonen 2009 Role of autophagy in the host defense against Toxoplasma gondii in astrocytes Autophagy 5 268 269 1:CAS:528:DC%2BD1MXovFeiu74%3D 10.4161/auto.5.2.7637 19139630
-
(2009)
Autophagy
, vol.5
, pp. 268-269
-
-
Halonen, S.K.1
-
33
-
-
0034861021
-
Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP
-
DOI 10.1128/IAI.69.9.5573-5576.2001
-
SK Halonen GA Taylor LM Weiss 2001 Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP Infect Immun 69 5573 5576 1:CAS:528:DC%2BD3MXmsVars70%3D 10.1128/IAI.69.9.5573-5576.2001 11500431 (Pubitemid 32786493)
-
(2001)
Infection and Immunity
, vol.69
, Issue.9
, pp. 5573-5576
-
-
Halonen, S.K.1
Taylor, G.A.2
Weiss, L.M.3
-
34
-
-
38449116497
-
Impaired macrophage function underscores susceptibility to Salmonella in mice lacking Irgm1 (LRG-47)
-
1:CAS:528:DC%2BD2sXht1Crs73P 17982087
-
SC Henry X Daniell M Indaram JF Whitesides GD Sempowski, et al. 2007 Impaired macrophage function underscores susceptibility to Salmonella in mice lacking Irgm1 (LRG-47) J Immunol 179 6963 6972 1:CAS:528:DC%2BD2sXht1Crs73P 17982087
-
(2007)
J Immunol
, vol.179
, pp. 6963-6972
-
-
Henry, S.C.1
Daniell, X.2
Indaram, M.3
Whitesides, J.F.4
Sempowski, G.D.5
-
35
-
-
65549154275
-
Balance of Irgm protein activities determines IFN-{gamma}-induced host defense
-
1:CAS:528:DC%2BD1MXlvVCks7k%3D 10.1189/jlb.1008599 19176402
-
SC Henry XG Daniell AR Burroughs M Indaram DN Howell, et al. 2009 Balance of Irgm protein activities determines IFN-{gamma}-induced host defense J Leukoc Biol 85 877 885 1:CAS:528:DC%2BD1MXlvVCks7k%3D 10.1189/jlb.1008599 19176402
-
(2009)
J Leukoc Biol
, vol.85
, pp. 877-885
-
-
Henry, S.C.1
Daniell, X.G.2
Burroughs, A.R.3
Indaram, M.4
Howell, D.N.5
-
36
-
-
76149089546
-
Regulation of macrophage motility by Irgm1
-
1:CAS:528:DC%2BC3cXhsFeisr4%3D 10.1189/jlb.0509299 19920210
-
SC Henry M Traver X Daniell M Indaram T Oliver, et al. 2010 Regulation of macrophage motility by Irgm1 J Leukoc Biol 87 2 333 343 1:CAS:528: DC%2BC3cXhsFeisr4%3D 10.1189/jlb.0509299 19920210
-
(2010)
J Leukoc Biol
, vol.87
, Issue.2
, pp. 333-343
-
-
Henry, S.C.1
Traver, M.2
Daniell, X.3
Indaram, M.4
Oliver, T.5
-
37
-
-
0028886480
-
Toxoplasma gondii comprises three clonal lineages: Correlation of parasite genotype with human disease
-
1:STN:280:DyaK28%2FotlGjsA%3D%3D 7594717
-
DK Howe LD Sibley 1995 Toxoplasma gondii comprises three clonal lineages: correlation of parasite genotype with human disease J Infect Dis 172 1561 1566 1:STN:280:DyaK28%2FotlGjsA%3D%3D 7594717
-
(1995)
J Infect Dis
, vol.172
, pp. 1561-1566
-
-
Howe, D.K.1
Sibley, L.D.2
-
38
-
-
77957687715
-
The mouse resistance protein Irgm1 (LRG-47): A regulator or an effector of pathogen defense?
-
10.1371/journal.ppat.1001008 20664789
-
JP Hunn JC Howard 2010 The mouse resistance protein Irgm1 (LRG-47): A regulator or an effector of pathogen defense? PLoS Pathog 6 e1001008 10.1371/journal.ppat.1001008 20664789
-
(2010)
PLoS Pathog
, vol.6
, pp. 1001008
-
-
Hunn, J.P.1
Howard, J.C.2
-
39
-
-
53549109432
-
Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii
-
1:CAS:528:DC%2BD1cXht1SlsLbL 10.1038/emboj.2008.176 18772884
-
JP Hunn S Koenen-Waisman N Papic N Schroeder N Pawlowski, et al. 2008 Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii EMBO J 27 2495 2509 1:CAS:528:DC%2BD1cXht1SlsLbL 10.1038/emboj.2008.176 18772884
-
(2008)
EMBO J
, vol.27
, pp. 2495-2509
-
-
Hunn, J.P.1
Koenen-Waisman, S.2
Papic, N.3
Schroeder, N.4
Pawlowski, N.5
-
40
-
-
70349672696
-
Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains
-
10.1371/journal.ppat.1000577 19750224
-
CD Intemann T Thye S Niemann EN Browne M Amanua Chinbuah, et al. 2009 Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains PLoS Pathog 5 e1000577 10.1371/journal.ppat.1000577 19750224
-
(2009)
PLoS Pathog
, vol.5
, pp. 1000577
-
-
Intemann, C.D.1
Thye, T.2
Niemann, S.3
Browne, E.N.4
Amanua Chinbuah, M.5
-
41
-
-
0026691182
-
The rapid generation of mutation data matrices from protein sequences
-
1:CAS:528:DyaK38Xlt1Okt7w%3D 1633570
-
DT Jones WR Taylor JM Thornton 1992 The rapid generation of mutation data matrices from protein sequences Comput Appl Biosci 8 275 282 1:CAS:528:DyaK38Xlt1Okt7w%3D 1633570
-
(1992)
Comput Appl Biosci
, vol.8
, pp. 275-282
-
-
Jones, D.T.1
Taylor, W.R.2
Thornton, J.M.3
-
42
-
-
77954430293
-
Coordinated loading of IRG resistance GTPases onto the Toxoplasma gondii parasitophorous vacuole
-
1:CAS:528:DC%2BC3cXotlKisbg%3D 10.1111/j.1462-5822.2010.01443.x 20109161
-
A Khaminets JP Hunn S Konen-Waisman YO Zhao D Preukschat, et al. 2010 Coordinated loading of IRG resistance GTPases onto the Toxoplasma gondii parasitophorous vacuole Cell Microbiol 12 7 939 961 1:CAS:528: DC%2BC3cXotlKisbg%3D 10.1111/j.1462-5822.2010.01443.x 20109161
-
(2010)
Cell Microbiol
, vol.12
, Issue.7
, pp. 939-961
-
-
Khaminets, A.1
Hunn, J.P.2
Konen-Waisman, S.3
Zhao, Y.O.4
Preukschat, D.5
-
43
-
-
35548991888
-
Recent transcontinental sweep of Toxoplasma gondii driven by a single monomorphic chromosome
-
DOI 10.1073/pnas.0702356104
-
A Khan B Fux C Su JP Dubey ML Darde, et al. 2007 Recent transcontinental sweep of Toxoplasma gondii driven by a single monomorphic chromosome Proc Natl Acad Sci USA 104 14872 14877 1:CAS:528:DC%2BD2sXhtVOnsLfF 10.1073/pnas. 0702356104 17804804 (Pubitemid 350003235)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.37
, pp. 14872-14877
-
-
Khan, A.1
Fux, B.2
Su, C.3
Dubey, J.P.4
Darde, M.L.5
Ajioka, J.W.6
Rosenthal, B.M.7
Sibley, L.D.8
-
44
-
-
62149118305
-
Selection at a single locus leads to widespread expansion of Toxoplasma gondii lineages that are virulent in mice
-
10.1371/journal.pgen.1000404 19266027
-
A Khan S Taylor JW Ajioka BM Rosenthal LD Sibley 2009 Selection at a single locus leads to widespread expansion of Toxoplasma gondii lineages that are virulent in mice PLoS Genet 5 e1000404 10.1371/journal.pgen.1000404 19266027
-
(2009)
PLoS Genet
, vol.5
, pp. 1000404
-
-
Khan, A.1
Taylor, S.2
Ajioka, J.W.3
Rosenthal, B.M.4
Sibley, L.D.5
-
45
-
-
33750833949
-
TLR-dependent induction of IFN-β mediates host defense against Trypanosoma cruzi
-
R Koga S Hamano H Kuwata K Atarashi M Ogawa H Hisaeda M Yamamoto S Akira K Himeno M Matsumoto K Takeda 2006 TLR-dependent induction of IFN-beta mediates host defense against Trypanosoma cruzi J Immunol 177 7059 7066 1:CAS:528:DC%2BD28XhtFGrtrvP 17082622 (Pubitemid 44715073)
-
(2006)
Journal of Immunology
, vol.177
, Issue.10
, pp. 7059-7066
-
-
Koga, R.1
Hamano, S.2
Kuwata, H.3
Atarashi, K.4
Ogawa, M.5
Hisaeda, H.6
Yamamoto, M.7
Akira, S.8
Himeno, K.9
Matsumoto, M.10
Takeda, K.11
-
46
-
-
36749068951
-
Cell-autonomous immunity to Toxoplasma gondii in mouse and man
-
DOI 10.1016/j.micinf.2007.09.005, PII S1286457907002857, Forum on Cell-Autonomous Imunity
-
S Konen-Waisman JC Howard 2007 Cell-autonomous immunity to Toxoplasma gondii in mouse and man Microbes Infect 9 1652 1661 10.1016/j.micinf.2007.09.005 18024121 (Pubitemid 350217084)
-
(2007)
Microbes and Infection
, vol.9
, Issue.14-15
, pp. 1652-1661
-
-
Konen-Waisman, S.1
Howard, J.C.2
-
47
-
-
0028929928
-
Cloning and characterization of a novel cDNA that is IFN-gamma-induced in mouse peritoneal macrophages and encodes a putative GTP-binding protein
-
1:CAS:528:DyaK2MXktlOlu74%3D 7884320
-
WP Lafuse D Brown L Castle BS Zwilling 1995 Cloning and characterization of a novel cDNA that is IFN-gamma-induced in mouse peritoneal macrophages and encodes a putative GTP-binding protein J Leukoc Biol 57 477 483 1:CAS:528:DyaK2MXktlOlu74%3D 7884320
-
(1995)
J Leukoc Biol
, vol.57
, pp. 477-483
-
-
Lafuse, W.P.1
Brown, D.2
Castle, L.3
Zwilling, B.S.4
-
48
-
-
67649376348
-
The evolutionarily dynamic IFN-inducible GTPase proteins play conserved immune functions in vertebrates and cephalochordates
-
1:CAS:528:DC%2BD1MXntlGjur0%3D 10.1093/molbev/msp074 19369598
-
G Li J Zhang Y Sun H Wang Y Wang 2009 The evolutionarily dynamic IFN-inducible GTPase proteins play conserved immune functions in vertebrates and cephalochordates Mol Biol Evol 26 1619 1630 1:CAS:528:DC%2BD1MXntlGjur0%3D 10.1093/molbev/msp074 19369598
-
(2009)
Mol Biol Evol
, vol.26
, pp. 1619-1630
-
-
Li, G.1
Zhang, J.2
Sun, Y.3
Wang, H.4
Wang, Y.5
-
49
-
-
33748444233
-
Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages
-
1:CAS:528:DC%2BD28XptlSgs78%3D 10.1084/jem.20061318 16940170
-
YM Ling MH Shaw C Ayala I Coppens GA Taylor, et al. 2006 Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages J Exp Med 203 2063 2071 1:CAS:528: DC%2BD28XptlSgs78%3D 10.1084/jem.20061318 16940170
-
(2006)
J Exp Med
, vol.203
, pp. 2063-2071
-
-
Ling, Y.M.1
Shaw, M.H.2
Ayala, C.3
Coppens, I.4
Taylor, G.A.5
-
50
-
-
0142240338
-
Immune control of tuberculosis by IFN-γ-inducible LRG-47
-
DOI 10.1126/science.1088063
-
JD MacMicking GA Taylor JD McKinney 2003 Immune control of tuberculosis by IFN-gamma-inducible LRG-47 Science 302 654 659 1:CAS:528:DC%2BD3sXotlWqtL8%3D 10.1126/science.1088063 14576437 (Pubitemid 37310923)
-
(2003)
Science
, vol.302
, Issue.5645
, pp. 654-659
-
-
MacMicking, J.D.1
Taylor, G.A.2
McKinney, J.D.3
-
51
-
-
4043065683
-
Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: Retargeting to plasma membrane induced by phagocytosis
-
S Martens K Sabel R Lange R Uthaiah E Wolf, et al. 2004 Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis J Immunol 173 2594 2606 1:CAS:528:DC%2BD2cXmt1Olurw%3D 15294976 (Pubitemid 39063119)
-
(2004)
Journal of Immunology
, vol.173
, Issue.4
, pp. 2594-2606
-
-
Martens, S.1
Sabel, K.2
Lange, R.3
Uthaiah, R.4
Wolf, E.5
Howard, J.C.6
-
52
-
-
49649126253
-
Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases
-
10.1371/journal.ppat.0010024 16304607
-
S Martens I Parvanova J Zerrahn G Griffiths G Schell, et al. 2005 Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases PLoS Pathog 1 e24 10.1371/journal.ppat.0010024 16304607
-
(2005)
PLoS Pathog
, vol.1
, pp. 24
-
-
Martens, S.1
Parvanova, I.2
Zerrahn, J.3
Griffiths, G.4
Schell, G.5
-
53
-
-
50449091647
-
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
-
1:CAS:528:DC%2BD1cXhtVGgtrfK 10.1038/ng.215 19165925
-
SA McCarroll A Huett P Kuballa SD Chilewski A Landry, et al. 2008 Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease Nat Genet 40 1107 1112 1:CAS:528:DC%2BD1cXhtVGgtrfK 10.1038/ng.215 19165925
-
(2008)
Nat Genet
, vol.40
, pp. 1107-1112
-
-
McCarroll, S.A.1
Huett, A.2
Kuballa, P.3
Chilewski, S.D.4
Landry, A.5
-
54
-
-
55849126156
-
The gamma interferon (IFN-gamma)-inducible GTP-binding protein IGTP is necessary for toxoplasma vacuolar disruption and induces parasite egression in IFN-gamma-stimulated astrocytes
-
1:CAS:528:DC%2BD1cXhtlajtrvL 10.1128/IAI.01288-07 18765738
-
T Melzer A Duffy LM Weiss SK Halonen 2008 The gamma interferon (IFN-gamma)-inducible GTP-binding protein IGTP is necessary for toxoplasma vacuolar disruption and induces parasite egression in IFN-gamma-stimulated astrocytes Infect Immun 76 4883 4894 1:CAS:528:DC%2BD1cXhtlajtrvL 10.1128/IAI.01288-07 18765738
-
(2008)
Infect Immun
, vol.76
, pp. 4883-4894
-
-
Melzer, T.1
Duffy, A.2
Weiss, L.M.3
Halonen, S.K.4
-
55
-
-
34548644595
-
The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydia psittaci infection
-
1:CAS:528:DC%2BD2sXnvVynu7Y%3D 17641048
-
I Miyairi VR Tatireddigari OS Mahdi LA Rose RJ Belland, et al. 2007 The p47 GTPases Iigp2 and Irgb10 regulate innate immunity and inflammation to murine Chlamydia psittaci infection J Immunol 179 1814 1824 1:CAS:528: DC%2BD2sXnvVynu7Y%3D 17641048
-
(2007)
J Immunol
, vol.179
, pp. 1814-1824
-
-
Miyairi, I.1
Tatireddigari, V.R.2
Mahdi, O.S.3
Rose, L.A.4
Belland, R.J.5
-
56
-
-
23044496729
-
Chlamydial IFN-γ immune evasion is linked to host infection tropism
-
DOI 10.1073/pnas.0504198102
-
DE Nelson DP Virok H Wood C Roshick RM Johnson WM Whitmire DD Crane O Steele-Mortimer L Kari G McClarty HD Caldwell 2005 Chlamydial IFN-gamma immune evasion is linked to host infection tropism Proc Natl Acad Sci USA 102 10658 10663 1:CAS:528:DC%2BD2MXntVSiu7w%3D 10.1073/pnas.0504198102 16020528 (Pubitemid 41061610)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.30
, pp. 10658-10663
-
-
Nelson, D.E.1
Virok, D.P.2
Wood, H.3
Roshick, C.4
Johnson, R.M.5
Whitmire, W.M.6
Crane, D.D.7
Steele-Mortimer, O.8
Kari, L.9
McClarty, G.10
Caldwell, H.D.11
-
57
-
-
65249123215
-
Toxoplasma-induced autophagy: A window into nutritional futile cycles in mammalian cells?
-
1:CAS:528:DC%2BD1MXnvVyrs78%3D 10.4161/auto.5.3.7807 19305153
-
A Orlofsky 2009 Toxoplasma-induced autophagy: A window into nutritional futile cycles in mammalian cells? Autophagy 5 3 404 406 1:CAS:528: DC%2BD1MXnvVyrs78%3D 10.4161/auto.5.3.7807 19305153
-
(2009)
Autophagy
, vol.5
, Issue.3
, pp. 404-406
-
-
Orlofsky, A.1
-
58
-
-
57649115443
-
Inactive and active states of the interferon-inducible resistance GTPase, Irga6, in vivo
-
1:CAS:528:DC%2BD1cXhtlCjsbfM 10.1074/jbc.M804846200 18784077
-
N Papic JP Hunn N Pawlowski J Zerrahn JC Howard 2008 Inactive and active states of the interferon-inducible resistance GTPase, Irga6, in vivo J Biol Chem 283 32143 32151 1:CAS:528:DC%2BD1cXhtlCjsbfM 10.1074/jbc.M804846200 18784077
-
(2008)
J Biol Chem
, vol.283
, pp. 32143-32151
-
-
Papic, N.1
Hunn, J.P.2
Pawlowski, N.3
Zerrahn, J.4
Howard, J.C.5
-
59
-
-
34347338690
-
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
-
DOI 10.1038/ng2061, PII NG2061
-
M Parkes JC Barrett NJ Prescott M Tremelling CA Anderson, et al. 2007 Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility Nat Genet 39 830 832 1:CAS:528:DC%2BD2sXmvFKlsL4%3D 10.1038/ng2061 17554261 (Pubitemid 47014496)
-
(2007)
Nature Genetics
, vol.39
, Issue.7
, pp. 830-832
-
-
Parkes, M.1
Barrett, J.C.2
Prescott, N.J.3
Tremelling, M.4
Anderson, C.A.5
Fisher, S.A.6
Roberts, R.G.7
Nimmo, E.R.8
Cummings, F.R.9
Soars, D.10
Drummond, H.11
Lees, C.W.12
Khawaja, S.A.13
Bagnall, R.14
Burke, D.A.15
Todhunter, C.E.16
Ahmad, T.17
Onnie, C.M.18
McArdle, W.19
Strachan, D.20
Bethel, G.21
Bryan, C.22
Lewis, C.M.23
Deloukas, P.24
Forbes, A.25
Sanderson, J.26
Jewell, D.P.27
Satsangi, J.28
Mansfield, J.C.29
Cardon, L.30
Mathew, C.G.31
more..
-
60
-
-
0027501041
-
A functional GTP-binding motif is necessary for antiviral activity of Mx proteins
-
F Pitossi A Blank A Schroder A Schwarz P Hussi, et al. 1993 A functional GTP-binding motif is necessary for antiviral activity of Mx proteins J Virol 67 6726 6732 1:CAS:528:DyaK2cXmsFOq 8411374 (Pubitemid 23309141)
-
(1993)
Journal of Virology
, vol.67
, Issue.11
, pp. 6726-6732
-
-
Pitossi, F.1
Blank, A.2
Schroder, A.3
Schwarz, A.4
Hussi, P.5
Schwemmle, M.6
Pavlovic, J.7
Staeheli, P.8
-
61
-
-
0742288598
-
The dynamin superfamily: Universal membrane tubulation and fission molecules?
-
DOI 10.1038/nrm1313
-
GJ Praefcke HT McMahon 2004 The dynamin superfamily: universal membrane tubulation and fission molecules? Nat Rev Mol Cell Biol 5 133 147 1:CAS:528:DC%2BD2cXnsFOjsg%3D%3D 10.1038/nrm1313 15040446 (Pubitemid 38160256)
-
(2004)
Nature Reviews Molecular Cell Biology
, vol.5
, Issue.2
, pp. 133-147
-
-
Praefcke, G.J.K.1
McMahon, H.T.2
-
62
-
-
7044239234
-
Identification of residues in the human guanylate-binding protein 1 critical for nucleotide binding and cooperative GTP hydrolysis
-
DOI 10.1016/j.jmb.2004.09.026, PII S0022283604011684
-
GJ Praefcke S Kloep U Benscheid H Lilie B Prakash, et al. 2004 Identification of residues in the human guanylate-binding protein 1 critical for nucleotide binding and cooperative GTP hydrolysis J Mol Biol 344 257 269 1:CAS:528:DC%2BD2cXovVKktb4%3D 10.1016/j.jmb.2004.09.026 15504415 (Pubitemid 39422386)
-
(2004)
Journal of Molecular Biology
, vol.344
, Issue.1
, pp. 257-269
-
-
Praefcke, G.J.K.1
Kloep, S.2
Benscheid, U.3
Lilie, H.4
Prakash, B.5
Herrmann, C.6
-
63
-
-
0034598734
-
Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins
-
DOI 10.1038/35000617
-
B Prakash GJ Praefcke L Renault A Wittinghofer C Herrmann 2000 Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins Nature 403 567 571 1:CAS:528:DC%2BD3cXht1Wgt7Y%3D 10.1038/35000617 10676968 (Pubitemid 30082205)
-
(2000)
Nature
, vol.403
, Issue.6769
, pp. 567-571
-
-
Prakash, B.1
Praefcke, G.J.K.2
Renault, L.3
Wittinghofer, A.4
Herrmann, C.5
-
64
-
-
57649238675
-
Real-time visualization of dynamin-catalyzed membrane fission and vesicle release
-
1:CAS:528:DC%2BD1MXisFyisg%3D%3D 10.1016/j.cell.2008.11.020 19084268
-
TJ Pucadyil SL Schmid 2008 Real-time visualization of dynamin-catalyzed membrane fission and vesicle release Cell 135 1263 1275 1:CAS:528: DC%2BD1MXisFyisg%3D%3D 10.1016/j.cell.2008.11.020 19084268
-
(2008)
Cell
, vol.135
, pp. 1263-1275
-
-
Pucadyil, T.J.1
Schmid, S.L.2
-
65
-
-
29144436298
-
Mice deficient in LRG-47 display enhanced susceptibility to Trypanosoma cruzi infection associated with defective hemopoiesis and intracellular control of parasite growth
-
HC Santiago CG Feng A Bafica E Roffe RM Arantes, et al. 2005 Mice deficient in LRG-47 display enhanced susceptibility to Trypanosoma cruzi infection associated with defective hemopoiesis and intracellular control of parasite growth J Immunol 175 8165 8172 1:CAS:528:DC%2BD2MXht12jt7zK 16339555 (Pubitemid 41798380)
-
(2005)
Journal of Immunology
, vol.175
, Issue.12
, pp. 8165-8172
-
-
Santiago, H.C.1
Feng, C.G.2
Bafica, A.3
Roffe, E.4
Arantes, R.M.5
Cheever, A.6
Taylor, G.7
Vierira, L.Q.8
Aliberti, J.9
Gazzinelli, R.T.10
Sher, A.11
-
66
-
-
53849092760
-
Population structure of Toxoplasma gondii: Clonal expansion driven by infrequent recombination and selective sweeps
-
1:CAS:528:DC%2BD1cXht1Gls73I 10.1146/annurev.micro.62.081307.162925 18544039
-
LD Sibley JW Ajioka 2008 Population structure of Toxoplasma gondii: clonal expansion driven by infrequent recombination and selective sweeps Annu Rev Microbiol 62 329 351 1:CAS:528:DC%2BD1cXht1Gls73I 10.1146/annurev.micro.62. 081307.162925 18544039
-
(2008)
Annu Rev Microbiol
, vol.62
, pp. 329-351
-
-
Sibley, L.D.1
Ajioka, J.W.2
-
68
-
-
33748506089
-
Human IRGM induces autophagy to eliminate intracellular mycobacteria
-
DOI 10.1126/science.1129577
-
SB Singh AS Davis GA Taylor V Deretic 2006 Human IRGM induces autophagy to eliminate intracellular mycobacteria Science 313 1438 1441 1:CAS:528:DC%2BD28XptFWju7o%3D 10.1126/science.1129577 16888103 (Pubitemid 44360272)
-
(2006)
Science
, vol.313
, Issue.5792
, pp. 1438-1441
-
-
Singh, S.B.1
Davis, A.S.2
Taylor, G.A.3
Deretic, V.4
-
69
-
-
0028837679
-
Identification of an endotoxin and IFN-inducible cDNA: Possible identification of a novel protein family
-
1:CAS:528:DyaK2MXos1anu7k%3D 7561525
-
JM Sorace RJ Johnson DL Howard BE Drysdale 1995 Identification of an endotoxin and IFN-inducible cDNA: possible identification of a novel protein family J Leukoc Biol 58 477 484 1:CAS:528:DyaK2MXos1anu7k%3D 7561525
-
(1995)
J Leukoc Biol
, vol.58
, pp. 477-484
-
-
Sorace, J.M.1
Johnson, R.J.2
Howard, D.L.3
Drysdale, B.E.4
-
70
-
-
0032511190
-
Dynamin undergoes a GTP-dependent conformational change causing vesiculation
-
DOI 10.1016/S0092-8674(00)81207-6
-
SM Sweitzer JE Hinshaw 1998 Dynamin undergoes a GTP-dependent conformational change causing vesiculation Cell 93 1021 1029 1:CAS:528:DyaK1cXjvFKqsLc%3D 10.1016/S0092-8674(00)81207-6 9635431 (Pubitemid 28280795)
-
(1998)
Cell
, vol.93
, Issue.6
, pp. 1021-1029
-
-
Sweitzer, S.M.1
Hinshaw, J.E.2
-
71
-
-
34047256441
-
IRG proteins: Key mediators of interferon-regulated host resistance to intracellular pathogens
-
DOI 10.1111/j.1462-5822.2007.00916.x
-
GA Taylor 2007 IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens Cell Microbiol 9 1099 1107 1:CAS:528:DC%2BD2sXkvFSlsrY%3D 10.1111/j.1462-5822.2007.00916.x 17359233 (Pubitemid 46547130)
-
(2007)
Cellular Microbiology
, vol.9
, Issue.5
, pp. 1099-1107
-
-
Taylor, G.A.1
-
72
-
-
0029832205
-
Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon γ
-
DOI 10.1074/jbc.271.34.20399
-
GA Taylor M Jeffers DA Largaespada NA Jenkins NG Copeland, et al. 1996 Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma J Biol Chem 271 20399 20405 1:CAS:528:DyaK28Xlt1ygtbY%3D 10.1074/jbc.271.34.20399 8702776 (Pubitemid 26281808)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.34
, pp. 20399-20405
-
-
Taylor, G.A.1
Jeffers, M.2
Largaespada, D.A.3
Jenkins, N.A.4
Copeland, N.G.5
Vande Woude, G.F.6
-
73
-
-
0030978494
-
The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding
-
DOI 10.1074/jbc.272.16.10639
-
GA Taylor R Stauber S Rulong E Hudson V Pei, et al. 1997 The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding J Biol Chem 272 10639 10645 1:CAS:528:DyaK2sXisl2qs7o%3D 10.1074/jbc.272.16.10639 9099712 (Pubitemid 27181073)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.16
, pp. 10639-10645
-
-
Taylor, G.A.1
Stauber, R.2
Rulong, S.3
Hudson, E.4
Pei, V.5
Pavlakis, G.N.6
Resau, J.H.7
Vande Woude, G.F.8
-
74
-
-
0034681123
-
Pathogen-specific loss of host resistance in mice lacking the IFN-γ- inducible gene IGTP
-
DOI 10.1073/pnas.97.2.751
-
GA Taylor CM Collazo GS Yap K Nguyen TA Gregorio, et al. 2000 Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP Proc Natl Acad Sci USA 97 751 755 1:CAS:528:DC%2BD3cXot1agtA%3D%3D 10.1073/pnas.97.2.751 10639151 (Pubitemid 30070381)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.2
, pp. 751-755
-
-
Taylor, G.A.1
Collazo, C.M.2
Yap, G.S.3
Nguyen, K.4
Gregorio, T.A.5
Taylor, L.S.6
Eagleson, B.7
Secrest, L.8
Southon, E.A.9
Reid, S.W.10
Tessarollo, L.11
Bray, M.12
McVicar, D.W.13
Komschlies, K.L.14
Young, H.A.15
Biron, C.A.16
Sher, A.17
Vande Woude, G.F.18
-
75
-
-
1142298755
-
p47 GTPases: Regulators of immunity to intracellular pathogens
-
GA Taylor CG Feng A Sher 2004 p47 GTPases: regulators of immunity to intracellular pathogens Nat Rev Immunol 4 100 109 1:CAS:528:DC%2BD2cXhsVKqsro%3D 10.1038/nri1270 15040583 (Pubitemid 38209204)
-
(2004)
Nature Reviews Immunology
, vol.4
, Issue.2
, pp. 100-109
-
-
Taylor, G.A.1
Feng, C.G.2
Sher, A.3
-
76
-
-
33845705275
-
A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii
-
DOI 10.1126/science.1133643
-
S Taylor A Barragan C Su B Fux SJ Fentress, et al. 2006 A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii Science 314 1776 1780 1:CAS:528:DC%2BD28XhtlSqtLfJ 10.1126/science.1133643 17170305 (Pubitemid 44969089)
-
(2006)
Science
, vol.314
, Issue.5806
, pp. 1776-1780
-
-
Taylor, S.1
Barragan, A.2
Su, C.3
Fux, B.4
Fentress, S.J.5
Tang, K.6
Beatty, W.L.7
El Hajj, H.8
Jerome, M.9
Behnke, M.S.10
White, M.11
Wootton, J.C.12
Sibley, L.D.13
-
77
-
-
36749064729
-
Control of IFN-γ-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases)
-
DOI 10.1016/j.micinf.2007.09.004, PII S1286457907002845, Forum on Cell-Autonomous Imunity
-
GA Taylor CG Feng A Sher 2007 Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases) Microbes Infect 9 1644 1651 1:CAS:528:DC%2BD2sXhsVCjt7nN 10.1016/j.micinf.2007. 09.004 18023232 (Pubitemid 350225741)
-
(2007)
Microbes and Infection
, vol.9
, Issue.14-15
, pp. 1644-1651
-
-
Taylor, G.A.1
Feng, C.G.2
Sher, A.3
-
78
-
-
0028036711
-
Activation of dynamin GTPase is a result of positive cooperativity
-
PL Tuma CA Collins 1994 Activation of dynamin GTPase is a result of positive cooperativity J Biol Chem 269 30842 30847 1:CAS:528:DyaK2cXmslGisbk%3D 7983015 (Pubitemid 24377567)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.49
, pp. 30842-30847
-
-
Tuma, P.L.1
Collins, C.A.2
-
79
-
-
0043033168
-
IIGP1, an interferon-γ-inducible 47-kDa GTPase of the mouse, showing cooperative enzymatic activity and GTP-dependent multimerization
-
DOI 10.1074/jbc.M211973200
-
RC Uthaiah GJ Praefcke JC Howard C Herrmann 2003 IIGP1, an interferon-gamma-inducible 47-kDa GTPase of the mouse, showing cooperative enzymatic activity and GTP-dependent multimerization J Biol Chem 278 29336 29343 1:CAS:528:DC%2BD3sXlsl2mt7c%3D 10.1074/jbc.M211973200 12732635 (Pubitemid 36935850)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.31
, pp. 29336-29343
-
-
Uthaiah, R.C.1
Praefcke, G.J.K.2
Howard, J.C.3
Herrmann, C.4
-
80
-
-
59449103030
-
Host cell autophagy is induced by Toxoplasma gondii and contributes to parasite growth
-
1:CAS:528:DC%2BD1MXjtFOiuw%3D%3D 10.1074/jbc.M807890200 19028680
-
Y Wang LM Weiss A Orlofsky 2009 Host cell autophagy is induced by Toxoplasma gondii and contributes to parasite growth J Biol Chem 284 1694 1701 1:CAS:528:DC%2BD1MXjtFOiuw%3D%3D 10.1074/jbc.M807890200 19028680
-
(2009)
J Biol Chem
, vol.284
, pp. 1694-1701
-
-
Wang, Y.1
Weiss, L.M.2
Orlofsky, A.3
-
81
-
-
0029787352
-
Dynamin self-assembly stimulates its GTPase activity
-
DOI 10.1074/jbc.271.37.22310
-
DE Warnock JE Hinshaw SL Schmid 1996 Dynamin self-assembly stimulates its GTPase activity J Biol Chem 271 22310 22314 1:CAS:528:DyaK28XlslaitL4%3D 10.1074/jbc.271.37.22310 8798389 (Pubitemid 26304660)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.37
, pp. 22310-22314
-
-
Warnock, D.E.1
Hinshaw, J.E.2
Schmid, S.L.3
-
82
-
-
69449108432
-
A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1), in mouse liver
-
10.1371/journal.pone.0006787 20368812
-
J Zeng IA Parvanova JC Howard 2009 A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1), in mouse liver PLoS One 4 e6787 10.1371/journal.pone.0006787 20368812
-
(2009)
PLoS One
, vol.4
, pp. 6787
-
-
Zeng, J.1
Parvanova, I.A.2
Howard, J.C.3
-
83
-
-
55249109400
-
Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens
-
1:CAS:528:DC%2BD1cXhsVWku7fO 10.1016/j.chom.2008.10.003 18996346
-
Z Zhao B Fux M Goodwin IR Dunay D Strong, et al. 2008 Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens Cell Host Microbe 4 458 469 1:CAS:528:DC%2BD1cXhsVWku7fO 10.1016/j.chom.2008.10.003 18996346
-
(2008)
Cell Host Microbe
, vol.4
, pp. 458-469
-
-
Zhao, Z.1
Fux, B.2
Goodwin, M.3
Dunay, I.R.4
Strong, D.5
-
84
-
-
65449163019
-
Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages
-
1:CAS:528:DC%2BD1MXis12hsL8%3D 10.4049/jimmunol.0804190 19265156
-
Y Zhao DJ Ferguson DC Wilson JC Howard LD Sibley, et al. 2009 Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages J Immunol 182 3775 3781 1:CAS:528:DC%2BD1MXis12hsL8%3D 10.4049/jimmunol.0804190 19265156
-
(2009)
J Immunol
, vol.182
, pp. 3775-3781
-
-
Zhao, Y.1
Ferguson, D.J.2
Wilson, D.C.3
Howard, J.C.4
Sibley, L.D.5
-
85
-
-
61449117883
-
Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death
-
10.1371/journal.ppat.1000288 19197351
-
YO Zhao A Khaminets JP Hunn JC Howard 2009 Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death PLoS Pathog 5 e1000288 10.1371/journal.ppat.1000288 19197351
-
(2009)
PLoS Pathog
, vol.5
, pp. 1000288
-
-
Zhao, Y.O.1
Khaminets, A.2
Hunn, J.P.3
Howard, J.C.4
-
86
-
-
65549141857
-
Toxoplasma gondii and the Immunity-Related GTPase (IRG) resistance system in mice: A review
-
1:CAS:528:DC%2BD1MXotFOlu7s%3D 10.1590/S0074-02762009000200016 19430648
-
YO Zhao C Rohde JT Lilue S Konen-Waisman A Khaminets, et al. 2009 Toxoplasma gondii and the Immunity-Related GTPase (IRG) resistance system in mice: a review Mem Inst Oswaldo Cruz 104 234 240 1:CAS:528:DC%2BD1MXotFOlu7s%3D 10.1590/S0074-02762009000200016 19430648
-
(2009)
Mem Inst Oswaldo Cruz
, vol.104
, pp. 234-240
-
-
Zhao, Y.O.1
Rohde, C.2
Lilue, J.T.3
Konen-Waisman, S.4
Khaminets, A.5
|