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Volumn 96, Issue , 2011, Pages 141-161

5-HT 6 Receptor Ligands and their Antipsychotic Potential

Author keywords

[No Author keywords available]

Indexed keywords

3 PHENYLSULFONYL 8 (1 PIPERAZINYL)QUINOLINE; 4 AMINO N [2,6 BIS(METHYLAMINO) 4 PYRIMIDINYL]BENZENESULFONAMIDE; 5 CHLORO N [4 METHOXY 3 (1 PIPERAZINYL)PHENYL] 3 METHYL 2 BENZOTHIOPHENESULFONAMIDE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; CLOZAPINE; DIZOCILPINE; DOPAMINE; E 6801; HALOPERIDOL; LU AE 58054; N (3,5 DICHLORO 2 METHOXYPHENYL) 4 METHOXY 3 (1 PIPERAZINYL)BENZENESULFONAMIDE; NEUROLEPTIC AGENT; OLANZAPINE; RISPERIDONE; RO 43 68554; SB 258510A; SB 258585; SEROTONIN 6 ANTAGONIST; SEROTONIN 6 RECEPTOR; SEROTONIN AGONIST; SERTINDOLE; UNCLASSIFIED DRUG; VOLINANSERIN; WAY 181187; LIGAND; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

EID: 79951525244     PISSN: 00747742     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-385902-0.00006-1     Document Type: Chapter
Times cited : (26)

References (77)
  • 1
    • 33847125372 scopus 로고    scopus 로고
    • Sub-chronic psychotomimetic phencyclidine induces deficits in reversal learning and alterations in parvalbumin-immunoreactive expression in the rat
    • Abdul-Monim Z., Neill J.C., Reynolds G.P. Sub-chronic psychotomimetic phencyclidine induces deficits in reversal learning and alterations in parvalbumin-immunoreactive expression in the rat. J. Psychopharmacol. 2007, 21:198-205.
    • (2007) J. Psychopharmacol. , vol.21 , pp. 198-205
    • Abdul-Monim, Z.1    Neill, J.C.2    Reynolds, G.P.3
  • 2
    • 12244296144 scopus 로고    scopus 로고
    • The atypical antipsychotic ziprasidone, but not haloperidol, improves phencyclidine-induced cognitive deficits in a reversal learning task in the rat
    • Abdul-Monim Z., Reynolds G.P., Neill J.C. The atypical antipsychotic ziprasidone, but not haloperidol, improves phencyclidine-induced cognitive deficits in a reversal learning task in the rat. J. Psychopharmacol. 2003, 17:57-65.
    • (2003) J. Psychopharmacol. , vol.17 , pp. 57-65
    • Abdul-Monim, Z.1    Reynolds, G.P.2    Neill, J.C.3
  • 3
    • 33645056175 scopus 로고    scopus 로고
    • The effect of atypical and classical antipsychotics on sub-chronic PCP-induced cognitive deficits in a reversal-learning paradigm
    • Abdul-Monim Z., Reynolds G.P., Neill J.C. The effect of atypical and classical antipsychotics on sub-chronic PCP-induced cognitive deficits in a reversal-learning paradigm. Behav. Brain Res. 2006, 169:263-273.
    • (2006) Behav. Brain Res. , vol.169 , pp. 263-273
    • Abdul-Monim, Z.1    Reynolds, G.P.2    Neill, J.C.3
  • 4
    • 0019943797 scopus 로고
    • Pharmacological specificity of conditioned avoidance response inhibition in rats: inhibition by neuroleptics and correlation to dopamine receptor blockade
    • Arnt J. Pharmacological specificity of conditioned avoidance response inhibition in rats: inhibition by neuroleptics and correlation to dopamine receptor blockade. Acta Pharmacol. Toxicol. 1982, 51:321-329.
    • (1982) Acta Pharmacol. Toxicol. , vol.51 , pp. 321-329
    • Arnt, J.1
  • 5
    • 0029165098 scopus 로고
    • Differential effects of classical and newer antipsychotics on the hypermotility induced by two dose levels of d-amphetamine
    • Arnt J. Differential effects of classical and newer antipsychotics on the hypermotility induced by two dose levels of d-amphetamine. Eur. J. Pharmacol. 1995, 283:55-62.
    • (1995) Eur. J. Pharmacol. , vol.283 , pp. 55-62
    • Arnt, J.1
  • 7
    • 0032007608 scopus 로고    scopus 로고
    • Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence
    • Arnt J., Skarsfeldt T. Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence. Neuropsychopharmacology 1998, 18:63-101.
    • (1998) Neuropsychopharmacology , vol.18 , pp. 63-101
    • Arnt, J.1    Skarsfeldt, T.2
  • 8
    • 0032907531 scopus 로고    scopus 로고
    • Investigation of stretching behaviour induced by the selective 5-HT6 receptor antagonist, Ro 04-6790, in rats
    • Bentley J.C., Bourson A., Boess F.G., Fone K.C., Marsden C.A., Petit N., Sleight A.J. Investigation of stretching behaviour induced by the selective 5-HT6 receptor antagonist, Ro 04-6790, in rats. Br. J. Pharmacol. 1999, 126:1537-1542.
    • (1999) Br. J. Pharmacol. , vol.126 , pp. 1537-1542
    • Bentley, J.C.1    Bourson, A.2    Boess, F.G.3    Fone, K.C.4    Marsden, C.A.5    Petit, N.6    Sleight, A.J.7
  • 9
    • 0034212645 scopus 로고    scopus 로고
    • Medial frontal cortex mediates perceptual attentional set shifting in the rat
    • Birrell J.M., Brown V.J. Medial frontal cortex mediates perceptual attentional set shifting in the rat. J. Neurosci. 2000, 20:4320-4324.
    • (2000) J. Neurosci. , vol.20 , pp. 4320-4324
    • Birrell, J.M.1    Brown, V.J.2
  • 10
    • 33746277764 scopus 로고    scopus 로고
    • A null mutation of the serotonin 6 receptor alters acute responses to ethanol
    • Bonasera S.J., Chu H.M., Brennan T.J., Tecott L.H. A null mutation of the serotonin 6 receptor alters acute responses to ethanol. Neuropsychopharmacology 2006, 31:1801-1813.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1801-1813
    • Bonasera, S.J.1    Chu, H.M.2    Brennan, T.J.3    Tecott, L.H.4
  • 11
    • 0031593618 scopus 로고    scopus 로고
    • Involvement of 5-HT6 receptors in nigro-striatal function in rodents
    • Bourson A., Boess F.G., Bos M., Sleight A.J. Involvement of 5-HT6 receptors in nigro-striatal function in rodents. Br. J. Pharmacol. 1998, 125:1562-1566.
    • (1998) Br. J. Pharmacol. , vol.125 , pp. 1562-1566
    • Bourson, A.1    Boess, F.G.2    Bos, M.3    Sleight, A.J.4
  • 12
    • 70349652427 scopus 로고    scopus 로고
    • Reversal of cognitive deficits by an ampakine (CX516) and sertindole in two animal models of schizophrenia-sub-chronic and early postnatal PCP treatment in attentional set-shifting
    • Broberg B.V., Glenthoj B.Y., Dias R., Larsen D.B., Olsen C.K. Reversal of cognitive deficits by an ampakine (CX516) and sertindole in two animal models of schizophrenia-sub-chronic and early postnatal PCP treatment in attentional set-shifting. Psychopharmacology (Berl) 2009, 206:631-640.
    • (2009) Psychopharmacology (Berl) , vol.206 , pp. 631-640
    • Broberg, B.V.1    Glenthoj, B.Y.2    Dias, R.3    Larsen, D.B.4    Olsen, C.K.5
  • 13
    • 0018116725 scopus 로고
    • Acute and chronic haloperidol treatment: comparison of effects on nigral dopaminergic cell activity
    • Bunney B.S., Grace A.A. Acute and chronic haloperidol treatment: comparison of effects on nigral dopaminergic cell activity. Life Sci. 1978, 23:1715-1727.
    • (1978) Life Sci. , vol.23 , pp. 1715-1727
    • Bunney, B.S.1    Grace, A.A.2
  • 16
    • 0034782825 scopus 로고    scopus 로고
    • The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus
    • Dawson L.A., Nguyen H.Q., Li P. The 5-HT(6) receptor antagonist SB-271046 selectively enhances excitatory neurotransmission in the rat frontal cortex and hippocampus. Neuropsychopharmacology 2001, 25:662-668.
    • (2001) Neuropsychopharmacology , vol.25 , pp. 662-668
    • Dawson, L.A.1    Nguyen, H.Q.2    Li, P.3
  • 17
    • 69249221567 scopus 로고    scopus 로고
    • Mice mutant for genes associated with schizophrenia: common phenotype or distinct endophenotypes?
    • Desbonnet L., Waddington J.L., Tuathaigh C.M. Mice mutant for genes associated with schizophrenia: common phenotype or distinct endophenotypes?. Behav. Brain Res. 2009, 204:258-273.
    • (2009) Behav. Brain Res. , vol.204 , pp. 258-273
    • Desbonnet, L.1    Waddington, J.L.2    Tuathaigh, C.M.3
  • 18
    • 0036707514 scopus 로고    scopus 로고
    • 5-HT6 receptor binding sites in schizophrenia and following antipsychotic drug administration: autoradiographic studies with [125I]SB-258585
    • East S.Z., Burnet P.W., Leslie R.A., Roberts J.C., Harrison P.J. 5-HT6 receptor binding sites in schizophrenia and following antipsychotic drug administration: autoradiographic studies with [125I]SB-258585. Synapse 2002, 45:191-199.
    • (2002) Synapse , vol.45 , pp. 191-199
    • East, S.Z.1    Burnet, P.W.2    Leslie, R.A.3    Roberts, J.C.4    Harrison, P.J.5
  • 19
    • 43049083311 scopus 로고    scopus 로고
    • Subchronic and chronic PCP treatment produces temporally distinct deficits in attentional set shifting and prepulse inhibition in rats
    • Egerton A., Reid L., McGregor S., Cochran S.M., Morris B.J., Pratt J.A. Subchronic and chronic PCP treatment produces temporally distinct deficits in attentional set shifting and prepulse inhibition in rats. Psychopharmacology (Berl) 2008, 198:37-49.
    • (2008) Psychopharmacology (Berl) , vol.198 , pp. 37-49
    • Egerton, A.1    Reid, L.2    McGregor, S.3    Cochran, S.M.4    Morris, B.J.5    Pratt, J.A.6
  • 20
    • 33846262524 scopus 로고    scopus 로고
    • Gestational methylazoxymethanol acetate treatment impairs select cognitive functions: parallels to schizophrenia
    • Featherstone R.E., Rizos Z., Nobrega J.N., Kapur S., Fletcher P.J. Gestational methylazoxymethanol acetate treatment impairs select cognitive functions: parallels to schizophrenia. Neuropsychopharmacology 2007, 32:483-492.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 483-492
    • Featherstone, R.E.1    Rizos, Z.2    Nobrega, J.N.3    Kapur, S.4    Fletcher, P.J.5
  • 21
    • 37348999213 scopus 로고    scopus 로고
    • Increased expression of 5-HT6 receptors in the nucleus accumbens blocks the rewarding but not psychomotor activating properties of cocaine
    • Ferguson S.M., Mitchell E.S., Neumaier J.F. Increased expression of 5-HT6 receptors in the nucleus accumbens blocks the rewarding but not psychomotor activating properties of cocaine. Biol. Psychiatry 2008, 63:207-213.
    • (2008) Biol. Psychiatry , vol.63 , pp. 207-213
    • Ferguson, S.M.1    Mitchell, E.S.2    Neumaier, J.F.3
  • 22
    • 44149105604 scopus 로고    scopus 로고
    • The selective 5-HT6 receptor antagonists SB-271046 and SB-399885 potentiate NCAM PSA immunolabeling of dentate granule cells, but not neurogenesis, in the hippocampal formation of mature Wistar rats
    • Foley A.G., Hirst W.D., Gallagher H.C., Barry C., Hagan J.J., Upton N., Walsh F.S., Hunter A.J., Regan C.M. The selective 5-HT6 receptor antagonists SB-271046 and SB-399885 potentiate NCAM PSA immunolabeling of dentate granule cells, but not neurogenesis, in the hippocampal formation of mature Wistar rats. Neuropharmacology 2008, 54:1166-1174.
    • (2008) Neuropharmacology , vol.54 , pp. 1166-1174
    • Foley, A.G.1    Hirst, W.D.2    Gallagher, H.C.3    Barry, C.4    Hagan, J.J.5    Upton, N.6    Walsh, F.S.7    Hunter, A.J.8    Regan, C.M.9
  • 23
    • 45849149279 scopus 로고    scopus 로고
    • Behavioural and neurochemical effects of post-weaning social isolation in rodents-relevance to developmental neuropsychiatric disorders
    • Fone K.C., Porkess M.V. Behavioural and neurochemical effects of post-weaning social isolation in rodents-relevance to developmental neuropsychiatric disorders. Neurosci. Biobehav. Rev. 2008, 32:1087-1102.
    • (2008) Neurosci. Biobehav. Rev. , vol.32 , pp. 1087-1102
    • Fone, K.C.1    Porkess, M.V.2
  • 24
    • 0036167486 scopus 로고    scopus 로고
    • 5-HT(6) receptor antagonism potentiates the behavioral and neurochemical effects of amphetamine but not cocaine
    • Frantz K.J., Hansson K.J., Stouffer D.G., Parsons L.H. 5-HT(6) receptor antagonism potentiates the behavioral and neurochemical effects of amphetamine but not cocaine. Neuropharmacology 2002, 42:170-180.
    • (2002) Neuropharmacology , vol.42 , pp. 170-180
    • Frantz, K.J.1    Hansson, K.J.2    Stouffer, D.G.3    Parsons, L.H.4
  • 25
    • 58149393059 scopus 로고    scopus 로고
    • Developing translational animal models for symptoms of schizophrenia or bipolar mania
    • Geyer M.A. Developing translational animal models for symptoms of schizophrenia or bipolar mania. Neurotox. Res. 2008, 14:71-78.
    • (2008) Neurotox. Res. , vol.14 , pp. 71-78
    • Geyer, M.A.1
  • 26
    • 59449101039 scopus 로고    scopus 로고
    • Comparison of haloperidol, risperidone, sertindole, and modafinil to reverse an attentional set-shifting impairment following subchronic PCP administration in the rat - a back translational study
    • Goetghebeur P., Dias R. Comparison of haloperidol, risperidone, sertindole, and modafinil to reverse an attentional set-shifting impairment following subchronic PCP administration in the rat - a back translational study. Psychopharmacology (Berl) 2009, 202:287-293.
    • (2009) Psychopharmacology (Berl) , vol.202 , pp. 287-293
    • Goetghebeur, P.1    Dias, R.2
  • 27
    • 0031060092 scopus 로고    scopus 로고
    • Dopamine-cell depolarization block as a model for the therapeutic actions of antipsychotic drugs
    • Grace A.A., Bunney B.S., Moore H., Todd C.L. Dopamine-cell depolarization block as a model for the therapeutic actions of antipsychotic drugs. Trends Neurosci. 1997, 20:31-37.
    • (1997) Trends Neurosci. , vol.20 , pp. 31-37
    • Grace, A.A.1    Bunney, B.S.2    Moore, H.3    Todd, C.L.4
  • 28
    • 34548621479 scopus 로고    scopus 로고
    • Atypical antipsychotics attenuate a sub-chronic pcp-induced cognitive deficit in the novel object recognition task in the rat
    • Grayson B., Idris N.F., Neill J.C. Atypical antipsychotics attenuate a sub-chronic pcp-induced cognitive deficit in the novel object recognition task in the rat. Behav. Brain Res. 2007, 184:31-38.
    • (2007) Behav. Brain Res. , vol.184 , pp. 31-38
    • Grayson, B.1    Idris, N.F.2    Neill, J.C.3
  • 31
    • 72649104250 scopus 로고    scopus 로고
    • Sertindole improves sub-chronic PCP-induced reversal learning and episodic memory deficits in rodents: involvement of 5-HT(6) and 5-HT (2A) receptor mechanisms
    • Idris N., Neill J., Grayson B., Bang-Andersen B., Witten L.M., Brennum L.T., Arnt J. Sertindole improves sub-chronic PCP-induced reversal learning and episodic memory deficits in rodents: involvement of 5-HT(6) and 5-HT (2A) receptor mechanisms. Psychopharmacology (Berl) 2010, 208:23-36.
    • (2010) Psychopharmacology (Berl) , vol.208 , pp. 23-36
    • Idris, N.1    Neill, J.2    Grayson, B.3    Bang-Andersen, B.4    Witten, L.M.5    Brennum, L.T.6    Arnt, J.7
  • 32
    • 26444535836 scopus 로고    scopus 로고
    • Investigation of the effects of lamotrigine and clozapine in improving reversal-learning impairments induced by acute phencyclidine and d-amphetamine in the rat
    • Idris N.F., Repeto P., Neill J.C., Large C.H. Investigation of the effects of lamotrigine and clozapine in improving reversal-learning impairments induced by acute phencyclidine and d-amphetamine in the rat. Psychopharmacology (Berl) 2005, 179:336-348.
    • (2005) Psychopharmacology (Berl) , vol.179 , pp. 336-348
    • Idris, N.F.1    Repeto, P.2    Neill, J.C.3    Large, C.H.4
  • 33
    • 0032903301 scopus 로고    scopus 로고
    • The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia
    • Jentsch J.D., Roth R.H. The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia. Neuropsychopharmacology 1999, 20:201-225.
    • (1999) Neuropsychopharmacology , vol.20 , pp. 201-225
    • Jentsch, J.D.1    Roth, R.H.2
  • 35
    • 66249116695 scopus 로고    scopus 로고
    • Modeling cognitive endophenotypes of schizophrenia in mice
    • Kellendonk C., Simpson E.H., Kandel E.R. Modeling cognitive endophenotypes of schizophrenia in mice. Trends Neurosci. 2009, 32:347-358.
    • (2009) Trends Neurosci. , vol.32 , pp. 347-358
    • Kellendonk, C.1    Simpson, E.H.2    Kandel, E.R.3
  • 36
    • 79952485799 scopus 로고    scopus 로고
    • E-6801, a 5-HT(6) receptor agonist, improves recognition memory by combined modulation of cholinergic and glutamatergic neurotransmission in the rat. Psychopharmacology (Berl) (Epub April 20). doi: 10.1007/s00213-010-1854-3.
    • Kendall, I., Slotten, H. A., Codony, X., Burgueno, J., Pauwels, P. J., Vela, J. M., and Fone, K. C. (2010). E-6801, a 5-HT(6) receptor agonist, improves recognition memory by combined modulation of cholinergic and glutamatergic neurotransmission in the rat. Psychopharmacology (Berl) (Epub April 20). doi: 10.1007/s00213-010-1854-3.
    • (2010)
    • Kendall, I.1    Slotten, H.A.2    Codony, X.3    Burgueno, J.4    Pauwels, P.J.5    Vela, J.M.6    Fone, K.C.7
  • 37
    • 3042561627 scopus 로고    scopus 로고
    • 5-HT6 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing consolidation - an effect sensitive to NMDA receptor antagonism
    • King M.V., Sleight A.J., Woolley M.L., Topham I.A., Marsden C.A., Fone K.C. 5-HT6 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing consolidation - an effect sensitive to NMDA receptor antagonism. Neuropharmacology 2004, 47:195-204.
    • (2004) Neuropharmacology , vol.47 , pp. 195-204
    • King, M.V.1    Sleight, A.J.2    Woolley, M.L.3    Topham, I.A.4    Marsden, C.A.5    Fone, K.C.6
  • 38
    • 77955717936 scopus 로고    scopus 로고
    • Advancing a functional genomics for schizophrenia: psychopathological and cognitive phenotypes in mutants with gene disruption
    • Kirby B.P., Waddington J.L., O'Tuathaigh C.M. Advancing a functional genomics for schizophrenia: psychopathological and cognitive phenotypes in mutants with gene disruption. Brain Res. Bull. 2009, 83:162-176.
    • (2009) Brain Res. Bull. , vol.83 , pp. 162-176
    • Kirby, B.P.1    Waddington, J.L.2    O'Tuathaigh, C.M.3
  • 39
    • 0346250850 scopus 로고    scopus 로고
    • 5-HT6 receptor antagonist SB-271046 enhances extracellular levels of monoamines in the rat medial prefrontal cortex
    • Lacroix L.P., Dawson L.A., Hagan J.J., Heidbreder C.A. 5-HT6 receptor antagonist SB-271046 enhances extracellular levels of monoamines in the rat medial prefrontal cortex. Synapse 2004, 51:158-164.
    • (2004) Synapse , vol.51 , pp. 158-164
    • Lacroix, L.P.1    Dawson, L.A.2    Hagan, J.J.3    Heidbreder, C.A.4
  • 40
    • 0038107717 scopus 로고    scopus 로고
    • Effect of the 5-HT6 receptor antagonists Ro04-6790 and Ro65-7199 on latent inhibition and prepulse inhibition in the rat: comparison to clozapine
    • Leng A., Ouagazzal A., Feldon J., Higgins G.A. Effect of the 5-HT6 receptor antagonists Ro04-6790 and Ro65-7199 on latent inhibition and prepulse inhibition in the rat: comparison to clozapine. Pharmacol. Biochem. Behav. 2003, 75:281-288.
    • (2003) Pharmacol. Biochem. Behav. , vol.75 , pp. 281-288
    • Leng, A.1    Ouagazzal, A.2    Feldon, J.3    Higgins, G.A.4
  • 41
    • 63249122032 scopus 로고    scopus 로고
    • Cell and receptor type-specific alterations in markers of GABA neurotransmission in the prefrontal cortex of subjects with schizophrenia
    • Lewis D.A., Hashimoto T., Morris H.M. Cell and receptor type-specific alterations in markers of GABA neurotransmission in the prefrontal cortex of subjects with schizophrenia. Neurotox. Res. 2008, 14:237-248.
    • (2008) Neurotox. Res. , vol.14 , pp. 237-248
    • Lewis, D.A.1    Hashimoto, T.2    Morris, H.M.3
  • 42
    • 33749645423 scopus 로고    scopus 로고
    • Cognitive dysfunction in schizophrenia: convergence of gamma-aminobutyric acid and glutamate alterations
    • Lewis D.A., Moghaddam B. Cognitive dysfunction in schizophrenia: convergence of gamma-aminobutyric acid and glutamate alterations. Arch. Neurol. 2006, 63:1372-1376.
    • (2006) Arch. Neurol. , vol.63 , pp. 1372-1376
    • Lewis, D.A.1    Moghaddam, B.2
  • 43
    • 33846348402 scopus 로고    scopus 로고
    • 5-HT6 receptor antagonist SB-399885 potentiates haloperidol and risperidone-induced dopamine efflux in the medial prefrontal cortex or hippocampus
    • Li Z., Huang M., Prus A.J., Dai J., Meltzer H.Y. 5-HT6 receptor antagonist SB-399885 potentiates haloperidol and risperidone-induced dopamine efflux in the medial prefrontal cortex or hippocampus. Brain Res. 2007, 1134:70-78.
    • (2007) Brain Res. , vol.1134 , pp. 70-78
    • Li, Z.1    Huang, M.2    Prus, A.J.3    Dai, J.4    Meltzer, H.Y.5
  • 44
    • 61449095547 scopus 로고    scopus 로고
    • A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia
    • Lodge D.J., Behrens M.M., Grace A.A. A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia. J. Neurosci. 2009, 29:2344-2354.
    • (2009) J. Neurosci. , vol.29 , pp. 2344-2354
    • Lodge, D.J.1    Behrens, M.M.2    Grace, A.A.3
  • 45
    • 69249224450 scopus 로고    scopus 로고
    • Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophrenia
    • Lodge D.J., Grace A.A. Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophrenia. Behav. Brain Res. 2009, 204:306-312.
    • (2009) Behav. Brain Res. , vol.204 , pp. 306-312
    • Lodge, D.J.1    Grace, A.A.2
  • 46
    • 38149054026 scopus 로고    scopus 로고
    • Pro-cognitive effects of 5-HT6 receptor antagonists in the social recognition procedure in rats: implication of the frontal cortex
    • Loiseau F., Dekeyne A., Millan M.J. Pro-cognitive effects of 5-HT6 receptor antagonists in the social recognition procedure in rats: implication of the frontal cortex. Psychopharmacology (Berl) 2008, 196:93-104.
    • (2008) Psychopharmacology (Berl) , vol.196 , pp. 93-104
    • Loiseau, F.1    Dekeyne, A.2    Millan, M.J.3
  • 47
    • 40849097398 scopus 로고    scopus 로고
    • A preliminary investigation into the effects of antipsychotics on sub-chronic phencyclidine-induced deficits in attentional set-shifting in female rats
    • McLean S.L., Beck J.P., Woolley M.L., Neill J.C. A preliminary investigation into the effects of antipsychotics on sub-chronic phencyclidine-induced deficits in attentional set-shifting in female rats. Behav. Brain Res. 2008, 189:152-158.
    • (2008) Behav. Brain Res. , vol.189 , pp. 152-158
    • McLean, S.L.1    Beck, J.P.2    Woolley, M.L.3    Neill, J.C.4
  • 48
    • 1542313953 scopus 로고    scopus 로고
    • Effect of the acute and chronic administration of the selective 5-HT6 receptor antagonist SB-271046 on the activity of midbrain dopamine neurons in rats: an in vivo electrophysiological study
    • Minabe Y., Shirayama Y., Hashimoto K., Routledge C., Hagan J.J., Ashby C.R. Effect of the acute and chronic administration of the selective 5-HT6 receptor antagonist SB-271046 on the activity of midbrain dopamine neurons in rats: an in vivo electrophysiological study. Synapse 2004, 52:20-28.
    • (2004) Synapse , vol.52 , pp. 20-28
    • Minabe, Y.1    Shirayama, Y.2    Hashimoto, K.3    Routledge, C.4    Hagan, J.J.5    Ashby, C.R.6
  • 49
    • 28044437798 scopus 로고    scopus 로고
    • 5-HT6 receptors: a novel target for cognitive enhancement
    • Mitchell E.S., Neumaier J.F. 5-HT6 receptors: a novel target for cognitive enhancement. Pharmacol. Ther. 2005, 108:320-333.
    • (2005) Pharmacol. Ther. , vol.108 , pp. 320-333
    • Mitchell, E.S.1    Neumaier, J.F.2
  • 50
    • 36148938722 scopus 로고    scopus 로고
    • 5-HT6 receptor antagonist reversal of emotional learning and prepulse inhibition deficits induced by apomorphine or scopolamine
    • Mitchell E.S., Neumaier J.F. 5-HT6 receptor antagonist reversal of emotional learning and prepulse inhibition deficits induced by apomorphine or scopolamine. Pharmacol. Biochem. Behav. 2008, 88:291-298.
    • (2008) Pharmacol. Biochem. Behav. , vol.88 , pp. 291-298
    • Mitchell, E.S.1    Neumaier, J.F.2
  • 51
    • 0033588176 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
    • Mohn A.R., Gainetdinov R.R., Caron M.G., Koller B.H. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 1999, 98:427-436.
    • (1999) Cell , vol.98 , pp. 427-436
    • Mohn, A.R.1    Gainetdinov, R.R.2    Caron, M.G.3    Koller, B.H.4
  • 52
    • 79951527016 scopus 로고    scopus 로고
    • The 5-HT6 receptor antagonist, Lu AE58054 blocks the effect of 5-HT6 receptor-stimulated modulation of extracellular neurotransmitter levels in the medial prefrontal cortex of rats. Society of Neuroscience Abstracts, 405.28.
    • Mork, A., Karlsson, J. J., and Arnt, J. (2010). The 5-HT6 receptor antagonist, Lu AE58054 blocks the effect of 5-HT6 receptor-stimulated modulation of extracellular neurotransmitter levels in the medial prefrontal cortex of rats. Society of Neuroscience Abstracts, 405.28.
    • (2010)
    • Mork, A.1    Karlsson, J.J.2    Arnt, J.3
  • 53
    • 69049088714 scopus 로고    scopus 로고
    • Effect of sertindole on extracellular dopamine, acetylcholine, and glutamate in the medial prefrontal cortex of conscious rats: a comparison with risperidone and exploration of mechanisms involved
    • Mork A., Witten L.M., Arnt J. Effect of sertindole on extracellular dopamine, acetylcholine, and glutamate in the medial prefrontal cortex of conscious rats: a comparison with risperidone and exploration of mechanisms involved. Psychopharmacology (Berl) 2009, 206:39-49.
    • (2009) Psychopharmacology (Berl) , vol.206 , pp. 39-49
    • Mork, A.1    Witten, L.M.2    Arnt, J.3
  • 55
    • 41249090837 scopus 로고    scopus 로고
    • Using pharmacokinetic-pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics
    • Olsen C.K., Brennum L.T., Kreilgaard M. Using pharmacokinetic-pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics. Eur. J. Pharmacol. 2008, 584:318-327.
    • (2008) Eur. J. Pharmacol. , vol.584 , pp. 318-327
    • Olsen, C.K.1    Brennum, L.T.2    Kreilgaard, M.3
  • 56
    • 33644940123 scopus 로고    scopus 로고
    • Decrease in parvalbumin-expressing neurons in the hippocampus and increased phencyclidine-induced locomotor activity in the rat methylazoxymethanol (MAM) model of schizophrenia
    • Penschuck S., Flagstad P., Didriksen M., Leist M., Michael-Titus A.T. Decrease in parvalbumin-expressing neurons in the hippocampus and increased phencyclidine-induced locomotor activity in the rat methylazoxymethanol (MAM) model of schizophrenia. Eur. J. Neurosci. 2006, 23:279-284.
    • (2006) Eur. J. Neurosci. , vol.23 , pp. 279-284
    • Penschuck, S.1    Flagstad, P.2    Didriksen, M.3    Leist, M.4    Michael-Titus, A.T.5
  • 57
    • 39149098130 scopus 로고    scopus 로고
    • The selective 5-HT(6) receptor antagonist Ro 04-6790 attenuates psychotomimetic effects of the NMDA receptor antagonist MK-801
    • Pitsikas N., Zisopoulou S., Pappas I., Sakellaridis N. The selective 5-HT(6) receptor antagonist Ro 04-6790 attenuates psychotomimetic effects of the NMDA receptor antagonist MK-801. Behav. Brain Res. 2008, 188:304-309.
    • (2008) Behav. Brain Res. , vol.188 , pp. 304-309
    • Pitsikas, N.1    Zisopoulou, S.2    Pappas, I.3    Sakellaridis, N.4
  • 58
    • 0036119234 scopus 로고    scopus 로고
    • Effects of the 5-HT(6) receptor antagonist, SB-271046, in animal models for schizophrenia
    • Pouzet B., Didriksen M., Arnt J. Effects of the 5-HT(6) receptor antagonist, SB-271046, in animal models for schizophrenia. Pharmacol. Biochem. Behav. 2002, 71:635-643.
    • (2002) Pharmacol. Biochem. Behav. , vol.71 , pp. 635-643
    • Pouzet, B.1    Didriksen, M.2    Arnt, J.3
  • 59
    • 3242809106 scopus 로고    scopus 로고
    • Calcium binding protein markers of GABA deficits in schizophrenia - postmortem studies and animal models
    • Reynolds G.P., Abdul-Monim Z., Neill J.C., Zhang Z.J. Calcium binding protein markers of GABA deficits in schizophrenia - postmortem studies and animal models. Neurotox. Res. 2004, 6:57-61.
    • (2004) Neurotox. Res. , vol.6 , pp. 57-61
    • Reynolds, G.P.1    Abdul-Monim, Z.2    Neill, J.C.3    Zhang, Z.J.4
  • 60
    • 0037177441 scopus 로고    scopus 로고
    • The distribution of 5-HT(6) receptors in rat brain: an autoradiographic binding study using the radiolabelled 5-HT(6) receptor antagonist [(125)I]SB-258585
    • Roberts J.C., Reavill C., East S.Z., Harrison P.J., Patel S., Routledge C., Leslie R.A. The distribution of 5-HT(6) receptors in rat brain: an autoradiographic binding study using the radiolabelled 5-HT(6) receptor antagonist [(125)I]SB-258585. Brain Res. 2002, 934:49-57.
    • (2002) Brain Res. , vol.934 , pp. 49-57
    • Roberts, J.C.1    Reavill, C.2    East, S.Z.3    Harrison, P.J.4    Patel, S.5    Routledge, C.6    Leslie, R.A.7
  • 61
    • 16244376475 scopus 로고    scopus 로고
    • PDE10A inhibition reverses subchronic PCP-induced deficits in attentional set-shifting in rats
    • Rodefer J.S., Murphy E.R., Baxter M.G. PDE10A inhibition reverses subchronic PCP-induced deficits in attentional set-shifting in rats. Eur. J. Neurosci. 2005, 21:1070-1076.
    • (2005) Eur. J. Neurosci. , vol.21 , pp. 1070-1076
    • Rodefer, J.S.1    Murphy, E.R.2    Baxter, M.G.3
  • 62
    • 51749091526 scopus 로고    scopus 로고
    • Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT6 receptor antagonist: comparison among antipsychotics
    • Rodefer J.S., Nguyen T.N., Karlsson J.J., Arnt J. Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT6 receptor antagonist: comparison among antipsychotics. Neuropsychopharmacology 2008, 33:2657-2666.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2657-2666
    • Rodefer, J.S.1    Nguyen, T.N.2    Karlsson, J.J.3    Arnt, J.4
  • 63
    • 0032869421 scopus 로고    scopus 로고
    • Phencyclidine in the social interaction test: an animal model of schizophrenia with face and predictive validity
    • Sams-Dodd F. Phencyclidine in the social interaction test: an animal model of schizophrenia with face and predictive validity. Rev. Neurosci. 1999, 10:59-90.
    • (1999) Rev. Neurosci. , vol.10 , pp. 59-90
    • Sams-Dodd, F.1
  • 67
    • 0026571852 scopus 로고
    • Electrophysiological profile of the new atypical neuroleptic, sertindole, on midbrain dopamine neurones in rats: acute and repeated treatment
    • Skarsfeldt T. Electrophysiological profile of the new atypical neuroleptic, sertindole, on midbrain dopamine neurones in rats: acute and repeated treatment. Synapse 1992, 10:25-33.
    • (1992) Synapse , vol.10 , pp. 25-33
    • Skarsfeldt, T.1
  • 68
    • 0030007496 scopus 로고    scopus 로고
    • Differential effect of antipsychotics on place navigation of rats in the Morris water maze. A comparative study between novel and reference antipsychotics
    • Skarsfeldt T. Differential effect of antipsychotics on place navigation of rats in the Morris water maze. A comparative study between novel and reference antipsychotics. Psychopharmacology (Berl) 1996, 124:126-133.
    • (1996) Psychopharmacology (Berl) , vol.124 , pp. 126-133
    • Skarsfeldt, T.1
  • 69
    • 38049057135 scopus 로고    scopus 로고
    • Efficacy of antipsychotics to reverse phencyclidine-induced social interaction deficits in female rats - a preliminary investigation
    • Snigdha S., Neill J.C. Efficacy of antipsychotics to reverse phencyclidine-induced social interaction deficits in female rats - a preliminary investigation. Behav. Brain Res. 2008, 187:489-494.
    • (2008) Behav. Brain Res. , vol.187 , pp. 489-494
    • Snigdha, S.1    Neill, J.C.2
  • 70
    • 43249099229 scopus 로고    scopus 로고
    • Improvement of phencyclidine-induced social behaviour deficits in rats: involvement of 5-HT1A receptors
    • Snigdha S., Neill J.C. Improvement of phencyclidine-induced social behaviour deficits in rats: involvement of 5-HT1A receptors. Behav. Brain Res. 2008, 191:26-31.
    • (2008) Behav. Brain Res. , vol.191 , pp. 26-31
    • Snigdha, S.1    Neill, J.C.2
  • 71
    • 69249237024 scopus 로고    scopus 로고
    • The neonatal ventral hippocampal lesion as a heuristic neurodevelopmental model of schizophrenia
    • Tseng K.Y., Chambers R.A., Lipska B.K. The neonatal ventral hippocampal lesion as a heuristic neurodevelopmental model of schizophrenia. Behav. Brain Res. 2009, 204:295-305.
    • (2009) Behav. Brain Res. , vol.204 , pp. 295-305
    • Tseng, K.Y.1    Chambers, R.A.2    Lipska, B.K.3
  • 72
    • 46749118971 scopus 로고    scopus 로고
    • 5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease
    • Upton N., Chuang T.T., Hunter A.J., Virley D.J. 5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease. Neurotherapeutics 2008, 5:458-469.
    • (2008) Neurotherapeutics , vol.5 , pp. 458-469
    • Upton, N.1    Chuang, T.T.2    Hunter, A.J.3    Virley, D.J.4
  • 73
    • 49549088180 scopus 로고    scopus 로고
    • Postnatal phencyclidine administration selectively reduces adult cortical parvalbumin-containing interneurons
    • Wang C.Z., Yang S.F., Xia Y., Johnson K.M. Postnatal phencyclidine administration selectively reduces adult cortical parvalbumin-containing interneurons. Neuropsychopharmacology 2008, 33:2442-2455.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2442-2455
    • Wang, C.Z.1    Yang, S.F.2    Xia, Y.3    Johnson, K.M.4
  • 74
    • 0030018405 scopus 로고    scopus 로고
    • Colocalization of serotonin receptor subtypes 5-HT2A, 5-HT2C, and 5-HT6 with neuropeptides in rat striatum
    • Ward R.P., Dorsa D.M. Colocalization of serotonin receptor subtypes 5-HT2A, 5-HT2C, and 5-HT6 with neuropeptides in rat striatum. J. Comp. Neurol. 1996, 370:405-414.
    • (1996) J. Comp. Neurol. , vol.370 , pp. 405-414
    • Ward, R.P.1    Dorsa, D.M.2
  • 76
    • 79951533040 scopus 로고    scopus 로고
    • Effects of 5-HT6 antagonists on attenuating PCP-induced cognitive deficits in a rodent set-shifting (ED/ID) task. Society of Neuroscience Abstracts 264.23.
    • Wünsch, A. M., Nguyen, H. Q., Guynn, L., and Rodefer, J. S. (2006). Effects of 5-HT6 antagonists on attenuating PCP-induced cognitive deficits in a rodent set-shifting (ED/ID) task. Society of Neuroscience Abstracts 264.23.
    • (2006)
    • Wünsch, A.M.1    Nguyen, H.Q.2    Guynn, L.3    Rodefer, J.S.4
  • 77
    • 0032967875 scopus 로고    scopus 로고
    • The in vivo effects of olanzapine and other antipsychotic agents on receptor occupancy and antagonism of dopamine D1, D2, D3, 5HT2A and muscarinic receptors
    • Zhang W., Bymaster F.P. The in vivo effects of olanzapine and other antipsychotic agents on receptor occupancy and antagonism of dopamine D1, D2, D3, 5HT2A and muscarinic receptors. Psychopharmacology (Berl) 1999, 141:267-278.
    • (1999) Psychopharmacology (Berl) , vol.141 , pp. 267-278
    • Zhang, W.1    Bymaster, F.P.2


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