-
1
-
-
33750155593
-
Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase
-
Avruch J., Hara K., Lin Y., Liu M., Long X., Ortiz-Vega S., Yonezawa K. Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase. Oncogene 2006, 25:6361-6572.
-
(2006)
Oncogene
, vol.25
, pp. 6361-6572
-
-
Avruch, J.1
Hara, K.2
Lin, Y.3
Liu, M.4
Long, X.5
Ortiz-Vega, S.6
Yonezawa, K.7
-
2
-
-
36549040859
-
The selectivity of protein kinase inhibitors: a further update
-
Bain J., Plater L., Elliott M., Shpiro N., Hastie C.J., McLauchlan H., Klevernic I., Arthur J.S., Alessi D.R., Cohen P. The selectivity of protein kinase inhibitors: a further update. Biochem. J. 2007, 408:297-315.
-
(2007)
Biochem. J.
, vol.408
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
Shpiro, N.4
Hastie, C.J.5
McLauchlan, H.6
Klevernic, I.7
Arthur, J.S.8
Alessi, D.R.9
Cohen, P.10
-
3
-
-
0031860687
-
Environmental control of the cell cycle in Drosophila: nutrition activates mitotic and endoreplicative cells by distinct mechanisms
-
Britton J.S., Edgar B.A. Environmental control of the cell cycle in Drosophila: nutrition activates mitotic and endoreplicative cells by distinct mechanisms. Development 1998, 125:2149-2158.
-
(1998)
Development
, vol.125
, pp. 2149-2158
-
-
Britton, J.S.1
Edgar, B.A.2
-
4
-
-
0036484062
-
Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions
-
Britton J.S., Lockwood W.K., Li L., Cohen S.M., Edgar B.A. Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions. Dev. Cell 2002, 2:239-249.
-
(2002)
Dev. Cell
, vol.2
, pp. 239-249
-
-
Britton, J.S.1
Lockwood, W.K.2
Li, L.3
Cohen, S.M.4
Edgar, B.A.5
-
5
-
-
0035916357
-
An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control
-
Brogiolo W., Stocker H., Ikeya T., Rintelen F., Fernandez R., Hafen E. An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control. Curr. Biol. 2001, 11:213-221.
-
(2001)
Curr. Biol.
, vol.11
, pp. 213-221
-
-
Brogiolo, W.1
Stocker, H.2
Ikeya, T.3
Rintelen, F.4
Fernandez, R.5
Hafen, E.6
-
6
-
-
27144522538
-
Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release
-
Caldwell P.E., Walkiewicz M., Stern M. Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release. Curr. Biol. 2005, 15:1785-1795.
-
(2005)
Curr. Biol.
, vol.15
, pp. 1785-1795
-
-
Caldwell, P.E.1
Walkiewicz, M.2
Stern, M.3
-
7
-
-
27144524370
-
Antagonistic actions of ecdysone and insulins determine final size in Drosophila
-
Colombani J., Bianchini L., Layalle S., Pondeville E., Dauphin-Villemant C., Antoniewski C., Carre C., Noselli S., Leopold P. Antagonistic actions of ecdysone and insulins determine final size in Drosophila. Science 2005, 310:667-670.
-
(2005)
Science
, vol.310
, pp. 667-670
-
-
Colombani, J.1
Bianchini, L.2
Layalle, S.3
Pondeville, E.4
Dauphin-Villemant, C.5
Antoniewski, C.6
Carre, C.7
Noselli, S.8
Leopold, P.9
-
8
-
-
33845340819
-
How flies get their size: genetics meets physiology
-
Edgar B.A. How flies get their size: genetics meets physiology. Nat. Rev. Genet. 2006, 7:907-916.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 907-916
-
-
Edgar, B.A.1
-
9
-
-
33746257209
-
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
-
Engelman J.A., Luo J., Cantley L.C. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat. Rev. Genet. 2006, 7:606-619.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 606-619
-
-
Engelman, J.A.1
Luo, J.2
Cantley, L.C.3
-
10
-
-
14844334980
-
Ca2+ signaling in prothoracicotropic hormone-stimulated prothoracic gland cells of Manduca sexta: evidence for mobilization and entry mechanisms
-
Fellner S.K., Rybczynski R., Gilbert L.I. Ca2+ signaling in prothoracicotropic hormone-stimulated prothoracic gland cells of Manduca sexta: evidence for mobilization and entry mechanisms. Insect Biochem. Mol. Biol. 2005, 35:263-275.
-
(2005)
Insect Biochem. Mol. Biol.
, vol.35
, pp. 263-275
-
-
Fellner, S.K.1
Rybczynski, R.2
Gilbert, L.I.3
-
11
-
-
34247140294
-
Role of insulin-like signalling in Drosophila lifespan
-
Giannakou M.E., Partridge L. Role of insulin-like signalling in Drosophila lifespan. Trends Biochem. Sci. 2007, 32:180-188.
-
(2007)
Trends Biochem. Sci.
, vol.32
, pp. 180-188
-
-
Giannakou, M.E.1
Partridge, L.2
-
12
-
-
0036006850
-
Control and biochemical nature of the ecdysteroidogenic pathway
-
Gilbert L.I., Rybczynski R., Warren J.T. Control and biochemical nature of the ecdysteroidogenic pathway. Annu. Rev. Entomol. 2002, 47:883-916.
-
(2002)
Annu. Rev. Entomol.
, vol.47
, pp. 883-916
-
-
Gilbert, L.I.1
Rybczynski, R.2
Warren, J.T.3
-
13
-
-
0030200149
-
A deficiency in prothoracicotropic hormone transduction pathway during the early last larval instar of Bombyx mori
-
Gu S.H., Chow Y.S., Lin F.J., Wu J.L., Ho R.J. A deficiency in prothoracicotropic hormone transduction pathway during the early last larval instar of Bombyx mori. Mol. Cell. Endocrinol. 1996, 120:99-105.
-
(1996)
Mol. Cell. Endocrinol.
, vol.120
, pp. 99-105
-
-
Gu, S.H.1
Chow, Y.S.2
Lin, F.J.3
Wu, J.L.4
Ho, R.J.5
-
14
-
-
0031729381
-
Role of calcium in the stimulation of ecdysteroidogenesis by recombinant prothoracicotropic hormone in the prothoracic glands of the silkworm, Bombyx mori
-
Gu S.H., Chow Y.S., O'Reilly D.R. Role of calcium in the stimulation of ecdysteroidogenesis by recombinant prothoracicotropic hormone in the prothoracic glands of the silkworm, Bombyx mori. Insect Biochem. Mol. Biol. 1998, 28:861-867.
-
(1998)
Insect Biochem. Mol. Biol.
, vol.28
, pp. 861-867
-
-
Gu, S.H.1
Chow, Y.S.2
O'Reilly, D.R.3
-
15
-
-
0030897940
-
Involvement of juvenile hormone in regulation of prothoracicotropic hormone transduction during the early last larval instar of Bombyx mori
-
Gu S.H., Chow Y.S., Yin C.-M. Involvement of juvenile hormone in regulation of prothoracicotropic hormone transduction during the early last larval instar of Bombyx mori. Mol. Cell. Endocrinol. 1997, 127:109-116.
-
(1997)
Mol. Cell. Endocrinol.
, vol.127
, pp. 109-116
-
-
Gu, S.H.1
Chow, Y.S.2
Yin, C.-M.3
-
16
-
-
61349171234
-
Insulin stimulates ecdysteroidogenesis by prothoracic glands in the silkworm, Bombyx mori
-
Gu S.H., Lin J.L., Lin P.L., Chen C.H. Insulin stimulates ecdysteroidogenesis by prothoracic glands in the silkworm, Bombyx mori. Insect Biochem. Mol. Biol. 2009, 39:171-179.
-
(2009)
Insect Biochem. Mol. Biol.
, vol.39
, pp. 171-179
-
-
Gu, S.H.1
Lin, J.L.2
Lin, P.L.3
Chen, C.H.4
-
17
-
-
71249158508
-
PTTH-stimulated ERK phosphorylation in prothoracic glands of the silkworm, Bombyx mori: role of Ca2+/calmodulin and receptor tyrosine kinase
-
Gu S.H., Lin J.L., Lin P.L. PTTH-stimulated ERK phosphorylation in prothoracic glands of the silkworm, Bombyx mori: role of Ca2+/calmodulin and receptor tyrosine kinase. J. Insect Physiol. 2010, 56:93-101.
-
(2010)
J. Insect Physiol.
, vol.56
, pp. 93-101
-
-
Gu, S.H.1
Lin, J.L.2
Lin, P.L.3
-
18
-
-
0343674606
-
Temporal analysis of ecdysteroidogenic activity of the prothoracic glands during the fourth larval instar of the silkworm, Bombyx mori
-
Gu S.H., Tsia W.H., Chow Y.S. Temporal analysis of ecdysteroidogenic activity of the prothoracic glands during the fourth larval instar of the silkworm, Bombyx mori. Insect Biochem. Mol. Biol. 2000, 30:499-505.
-
(2000)
Insect Biochem. Mol. Biol.
, vol.30
, pp. 499-505
-
-
Gu, S.H.1
Tsia, W.H.2
Chow, Y.S.3
-
19
-
-
0041821493
-
Interplay between growth factor and nutrient signaling: lessons from Drosophila TOR
-
Hafen E. Interplay between growth factor and nutrient signaling: lessons from Drosophila TOR. Curr. Top. Microbiol. Immunol. 2004, 279:153-167.
-
(2004)
Curr. Top. Microbiol. Immunol.
, vol.279
, pp. 153-167
-
-
Hafen, E.1
-
20
-
-
4444347661
-
Drosophila PI3 kinase and Akt involved in insulin-stimulated proliferation and ERK pathway activation in Schneider cells
-
Kim S.-E., Cho J.-Y., Kim K.-S., Lee S.-J., Lee K.-H., Choi K.-Y. Drosophila PI3 kinase and Akt involved in insulin-stimulated proliferation and ERK pathway activation in Schneider cells. Cell. Signal. 2004, 16:1309-1317.
-
(2004)
Cell. Signal.
, vol.16
, pp. 1309-1317
-
-
Kim, S.-E.1
Cho, J.-Y.2
Kim, K.-S.3
Lee, S.-J.4
Lee, K.-H.5
Choi, K.-Y.6
-
21
-
-
34247873063
-
In vitro and in vivo stimulation of extracellular signal-regulated kinase (ERK) by prothoracicotropic hormone in prothoracic gland cells and its developmental regulation in the silkworm, Bombyx mori
-
Lin J.L., Gu S.H. In vitro and in vivo stimulation of extracellular signal-regulated kinase (ERK) by prothoracicotropic hormone in prothoracic gland cells and its developmental regulation in the silkworm, Bombyx mori. J. Insect Physiol. 2007, 53:622-631.
-
(2007)
J. Insect Physiol.
, vol.53
, pp. 622-631
-
-
Lin, J.L.1
Gu, S.H.2
-
22
-
-
79951546578
-
-
Prothoracicotropic hormone induces tyrosine phosphorylation in prothoracic glands of the silkworm, Published online June 21, 2010.
-
Lin, J.L., Gu, S.H., 2011. Prothoracicotropic hormone induces tyrosine phosphorylation in prothoracic glands of the silkworm, Bombyx mori. Arch. Insect Biochem. Physiol. Published online June 21, 2010. http://onlinelibrary.wiley.com/doi/10.1002/arch.20373.
-
(2011)
Bombyx mori. Arch. Insect Biochem. Physiol.
-
-
Lin, J.L.1
Gu, S.H.2
-
23
-
-
33645874515
-
PI3K is required for insulin-stimulated but not EGF-stimulated ERK1/2 activation
-
Liu L., Xie Y., Lou L. PI3K is required for insulin-stimulated but not EGF-stimulated ERK1/2 activation. Eur. J. Cell Biol. 2006, 85:367-374.
-
(2006)
Eur. J. Cell Biol.
, vol.85
, pp. 367-374
-
-
Liu, L.1
Xie, Y.2
Lou, L.3
-
24
-
-
77955431617
-
Transcriptional regulation of the insulin signaling pathway genes by starvation and 20-hydroxyecdysone in the Bombyx fat body
-
Liu Y., Zhou S., Ma L., Tian L., Wang S., Sheng Z., Jiang R.J., Bendena W.G., Li S. Transcriptional regulation of the insulin signaling pathway genes by starvation and 20-hydroxyecdysone in the Bombyx fat body. J. Insect Physiol. 2010, 56:1436-1444.
-
(2010)
J. Insect Physiol.
, vol.56
, pp. 1436-1444
-
-
Liu, Y.1
Zhou, S.2
Ma, L.3
Tian, L.4
Wang, S.5
Sheng, Z.6
Jiang, R.J.7
Bendena, W.G.8
Li, S.9
-
25
-
-
77049125934
-
Control of ecdysteroidogenesis in prothoracic glands of insects: a review
-
Marchal E., Vandersmissen H.P., Badisco L., Van de Velde S., Verlinden H., Iga M., Van Wielendaele P., Huybrechts R., Simonet G., Smagghe G., Vanden Broeck J. Control of ecdysteroidogenesis in prothoracic glands of insects: a review. Peptides 2010, 31:506-519.
-
(2010)
Peptides
, vol.31
, pp. 506-519
-
-
Marchal, E.1
Vandersmissen, H.P.2
Badisco, L.3
Van de Velde, S.4
Verlinden, H.5
Iga, M.6
Van Wielendaele, P.7
Huybrechts, R.8
Simonet, G.9
Smagghe, G.10
Vanden Broeck, J.11
-
26
-
-
36549022180
-
Prothoracicotropic hormone regulates developmental timing and body size in Drosophila
-
McBrayer Z., Ono H., Shimell M., Parvy J.-P., Beckstead R.B., Warren J.T., Thummel C.S., Dauphin-Villemant C., Gilbert L.I., O'Connor M.B. Prothoracicotropic hormone regulates developmental timing and body size in Drosophila. Dev. Cell 2007, 13:857-871.
-
(2007)
Dev. Cell
, vol.13
, pp. 857-871
-
-
McBrayer, Z.1
Ono, H.2
Shimell, M.3
Parvy, J.-P.4
Beckstead, R.B.5
Warren, J.T.6
Thummel, C.S.7
Dauphin-Villemant, C.8
Gilbert, L.I.9
O'Connor, M.B.10
-
27
-
-
27144511477
-
The role of the prothoracic gland in determining critical weight for metamorphosis in Drosophila melanogaster
-
Mirth C., Truman J.W., Riddiford L.M. The role of the prothoracic gland in determining critical weight for metamorphosis in Drosophila melanogaster. Curr. Biol. 2005, 15:1796-1807.
-
(2005)
Curr. Biol.
, vol.15
, pp. 1796-1807
-
-
Mirth, C.1
Truman, J.W.2
Riddiford, L.M.3
-
28
-
-
0029278690
-
Overexpression of Bombyx mori prothoracicotropic hormone using baculovirus vectors
-
O'Reilly D.R., Kelly T.J., Masler E.P., Thyagaraja B.S., Robson R.M., Shaw T.C., Miller L.K. Overexpression of Bombyx mori prothoracicotropic hormone using baculovirus vectors. Insect Biochem. Mol. Biol. 1995, 25:475-485.
-
(1995)
Insect Biochem. Mol. Biol.
, vol.25
, pp. 475-485
-
-
O'Reilly, D.R.1
Kelly, T.J.2
Masler, E.P.3
Thyagaraja, B.S.4
Robson, R.M.5
Shaw, T.C.6
Miller, L.K.7
-
29
-
-
0028217223
-
Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase
-
Powis G., Bonjouklian R., Berggren M.M., Gallegos A., Abraham R., Ashendel C., Zalkow L., Matter W.F., Dodge J., Grindey G., Vlahos C.J. Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase. Cancer Res. 1994, 54:2419-2423.
-
(1994)
Cancer Res.
, vol.54
, pp. 2419-2423
-
-
Powis, G.1
Bonjouklian, R.2
Berggren, M.M.3
Gallegos, A.4
Abraham, R.5
Ashendel, C.6
Zalkow, L.7
Matter, W.F.8
Dodge, J.9
Grindey, G.10
Vlahos, C.J.11
-
30
-
-
71549168637
-
The insect neuropeptide PTTH activates receptor tyrosine kinase torso to initiate metamorphosis
-
Rewitz K.F., Yamanaka N., Gilbert L.I., O'Connor M.B. The insect neuropeptide PTTH activates receptor tyrosine kinase torso to initiate metamorphosis. Science 2009, 326:1403-1405.
-
(2009)
Science
, vol.326
, pp. 1403-1405
-
-
Rewitz, K.F.1
Yamanaka, N.2
Gilbert, L.I.3
O'Connor, M.B.4
-
31
-
-
85069900935
-
Prothoracicotropic hormone
-
Elsevier, Oxford, UK, L.I. Gilbert, K. Iatrou, S. Gill (Eds.)
-
Rybczynski R. Prothoracicotropic hormone. Comprehensive Molecular Insect Science 2005, Vol. 3:1-123. Elsevier, Oxford, UK. L.I. Gilbert, K. Iatrou, S. Gill (Eds.).
-
(2005)
Comprehensive Molecular Insect Science
, vol.3
, pp. 1-123
-
-
Rybczynski, R.1
-
32
-
-
0035955886
-
Activation of an extracellular signal-regulated kinase (ERK) by the insect prothoracicotropic hormone
-
Rybczynski R., Bell S.C., Gilbert L.I. Activation of an extracellular signal-regulated kinase (ERK) by the insect prothoracicotropic hormone. Mol. Cell. Endocrinol. 2001, 184:1-11.
-
(2001)
Mol. Cell. Endocrinol.
, vol.184
, pp. 1-11
-
-
Rybczynski, R.1
Bell, S.C.2
Gilbert, L.I.3
-
34
-
-
0021948242
-
Calcium-cyclic AMP interactions in prothoracicotropic hormone stimulation of ecdysone synthesis
-
Smith W.A., Gilbert L.I., Bollenbacher W.E. Calcium-cyclic AMP interactions in prothoracicotropic hormone stimulation of ecdysone synthesis. Mol. Cell. Endocrinol. 1985, 39:71-78.
-
(1985)
Mol. Cell. Endocrinol.
, vol.39
, pp. 71-78
-
-
Smith, W.A.1
Gilbert, L.I.2
Bollenbacher, W.E.3
-
35
-
-
0027932618
-
S6 phosphorylation results from prothoracicotropic hormone stimulation of insect prothoracic glands: a role for S6 kinase
-
Song Q., Gilbert L.I. S6 phosphorylation results from prothoracicotropic hormone stimulation of insect prothoracic glands: a role for S6 kinase. Dev. Genet. 1994, 15:332-338.
-
(1994)
Dev. Genet.
, vol.15
, pp. 332-338
-
-
Song, Q.1
Gilbert, L.I.2
-
36
-
-
0029294746
-
Multiple phosphorylation of ribosomal protein S6 and specific protein synthesis are required for prothoracicotropic hormone-stimulated ecdysteroid biosynthesis in the prothoracic glands of Manduca sexta
-
Song Q., Gilbert L.I. Multiple phosphorylation of ribosomal protein S6 and specific protein synthesis are required for prothoracicotropic hormone-stimulated ecdysteroid biosynthesis in the prothoracic glands of Manduca sexta. Insect Biochem. Mol. Biol. 1995, 25:591-602.
-
(1995)
Insect Biochem. Mol. Biol.
, vol.25
, pp. 591-602
-
-
Song, Q.1
Gilbert, L.I.2
-
37
-
-
0031041455
-
Molecular cloning, developmental expression, and phosphorylation of ribosomal protein S6 in the endocrine gland responsible for insect molting
-
Song Q., Gilbert L.I. Molecular cloning, developmental expression, and phosphorylation of ribosomal protein S6 in the endocrine gland responsible for insect molting. J. Biol. Chem. 1997, 272:4429-4435.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4429-4435
-
-
Song, Q.1
Gilbert, L.I.2
-
38
-
-
0000946760
-
Preparation of anti-20-hydroxyecdysone serum and its application for radioimmunoassay of ecdysteroids in silkworm hemolymph
-
Takeda S., Kiuchi M., Ueda S. Preparation of anti-20-hydroxyecdysone serum and its application for radioimmunoassay of ecdysteroids in silkworm hemolymph. Bull. Sericult. Exp. Stn. Jpn. 1986, 30:361-374.
-
(1986)
Bull. Sericult. Exp. Stn. Jpn.
, vol.30
, pp. 361-374
-
-
Takeda, S.1
Kiuchi, M.2
Ueda, S.3
-
40
-
-
72449195397
-
Molecular mechanisms of metabolic regulation by insulin in Drosophila
-
Teleman A.A. Molecular mechanisms of metabolic regulation by insulin in Drosophila. Biochem. J. 2010, 425:13-26.
-
(2010)
Biochem. J.
, vol.425
, pp. 13-26
-
-
Teleman, A.A.1
-
41
-
-
77951621262
-
The emerging mechanisms of isoform-specific PI3K signalling
-
Vanhaesebroeck B., Guillermet-Guibert J., Graupera M., Bilanges B. The emerging mechanisms of isoform-specific PI3K signalling. Nat. Rev. Mol. Cell Biol. 2010, 11:329-341.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 329-341
-
-
Vanhaesebroeck, B.1
Guillermet-Guibert, J.2
Graupera, M.3
Bilanges, B.4
-
42
-
-
0028170210
-
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
-
Vlahos C.J., Matter W.F., Hui K.Y., Brown R.F. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J. Biol. Chem. 1994, 269:5241-5248.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
43
-
-
64549136220
-
Increased insulin/insulin growth factor signalling advances the onset of metamorphosis in Drosophila
-
Walkiewicz M., Stern M. Increased insulin/insulin growth factor signalling advances the onset of metamorphosis in Drosophila. PLoS ONE 2009, 4:e5072.
-
(2009)
PLoS ONE
, vol.4
-
-
Walkiewicz, M.1
Stern, M.2
-
44
-
-
30844437476
-
Signaling and function of insulin-like peptides in insects
-
Wu Q., Brown M.R. Signaling and function of insulin-like peptides in insects. Annu. Rev. Entomol. 2006, 51:1-24.
-
(2006)
Annu. Rev. Entomol.
, vol.51
, pp. 1-24
-
-
Wu, Q.1
Brown, M.R.2
|