Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars

Protein and Cell

Volumn 1, Issue 1, 2010, Pages 82-95

  Westwood, Isaac M ^a,d   Bhakta, Sanjib ^a,e   Russell, Angela J ^a   Fullam, Elizabeth ^a   Anderton, Matthew C ^a   Kawamura, Akane ^a   Mulvaney, Andrew W ^a   Vickers, Richard J ^a   Bhowruth, Veemal ^b   Besra, Gurdyal S ^b   Lalvani, Ajit ^c   Davies, Stephen G ^a   Sim, Edith ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^e UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Mycobacterium tuberculosis; N acetyltransferase; screening; triazoles

Indexed keywords

3' CHLOROPHENYL 1,2,4 TRIAZOLE 3 THIONE; 4 PHENYLBENZYL 1,2,4 TRIAZOLE 3 THIONE; 4' CHLOROPHENYL 1,2,4 TRIAZOLE 3 THIONE; 4' METHOXYPHENYL 1,2,4 TRIAZOLE 3 THIONE; 4' METHYLPHENYL 1,2,4 TRIAZOLE 3 THIONE; 5 TERT BUTYL 1,2,4 TRIAZOLE 3 THIONE; ACYLTRANSFERASE INHIBITOR; ARYLAMINE ACETYLTRANSFERASE; BENZYL 1,2,4 TRIAZOLE 3 THIONE; METHYL 1,2,4 TRIAZOLE 3 THIONE; N DECYL 1,2,4 TRIAZOLE 3 THIONE; N OCTYL 1,2,4 TRIAZOLE 3 THIONE; N PROPYL 1,2,4 TRIAZOLE 3 THIONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERIAL GROWTH; BACTERIAL SURVIVAL; CONTROLLED STUDY; DRUG DESIGN; DRUG SCREENING; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; MINIMUM INHIBITORY CONCENTRATION; MOUSE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

CORYNEBACTERINEAE; MYCOBACTERIUM BOVIS BCG; MYCOBACTERIUM TUBERCULOSIS;

EID: 79851511503     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-010-0006-1     Document Type: Article

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