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Volumn 307, Issue 5707, 2005, Pages 214-215
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TB - A new target, a new drug
a
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Author keywords
[No Author keywords available]
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Indexed keywords
ANTIINFECTIVE AGENT;
ETHAMBUTOL;
ISONIAZID;
MOXIFLOXACIN;
NEW DRUG;
PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;
PYRAZINAMIDE;
QUINOLINE DERIVATIVE;
RIFAMPICIN;
1 (6 BROMO 2 METHOXY QUINOLIN 3 YL) 4 DIMETHYLAMINO 2 (3 FLUOROPHENYL) 1 PHENYL BUTAN 2 OL;
1-(6-BROMO-2-METHOXY-QUINOLIN-3-YL)-4-DIMETHYLAMINO-2-(3-FLUOROPHENYL)-1-PHENYL-BUTAN-2-OL;
ADENOSINE TRIPHOSPHATE;
ENZYME INHIBITOR;
PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE;
TUBERCULOSTATIC AGENT;
DRUG DEVELOPMENT;
TUBERCULOSIS;
ANTIBACTERIAL ACTIVITY;
AWARENESS;
BINDING AFFINITY;
DEVELOPING COUNTRY;
DRUG DOSE REGIMEN;
DRUG INDUSTRY;
ENZYME ACTIVE SITE;
GENE SEQUENCE;
HUMAN;
HYDROGEN BOND;
MULTIDRUG RESISTANCE;
MYCOBACTERIUM TUBERCULOSIS;
NONHUMAN;
ORGANIZATION;
PRIORITY JOURNAL;
PROTON MOTIVE FORCE;
RELAPSE;
SHORT COURSE THERAPY;
SHORT SURVEY;
TUBERCULOSIS;
TUBERCULOSIS CONTROL;
UNITED STATES;
WORLD HEALTH ORGANIZATION;
ANIMAL;
ANTIBIOTIC RESISTANCE;
BIOSYNTHESIS;
CHEMISTRY;
DRUG ANTAGONISM;
DRUG DESIGN;
DRUG EFFECT;
DRUG SCREENING;
ENZYMOLOGY;
GENETICS;
METABOLISM;
MICROBIOLOGICAL EXAMINATION;
MICROBIOLOGY;
MOUSE;
MYCOBACTERIUM SMEGMATIS;
NOTE;
PHASE 2 CLINICAL TRIAL;
PROTEIN SECONDARY STRUCTURE;
MYCOBACTERIUM;
MYCOBACTERIUM TUBERCULOSIS;
ADENOSINE TRIPHOSPHATE;
ANIMALS;
ANTITUBERCULAR AGENTS;
BACTERIAL PROTON-TRANSLOCATING ATPASES;
CLINICAL TRIALS, PHASE II;
DRUG DESIGN;
DRUG EVALUATION, PRECLINICAL;
DRUG RESISTANCE, BACTERIAL;
ENZYME INHIBITORS;
HUMANS;
MICE;
MICROBIAL SENSITIVITY TESTS;
MYCOBACTERIUM SMEGMATIS;
MYCOBACTERIUM TUBERCULOSIS;
PROTEIN STRUCTURE, SECONDARY;
PROTON-MOTIVE FORCE;
PROTON-TRANSLOCATING ATPASES;
QUINOLINES;
TUBERCULOSIS;
TUBERCULOSIS, MULTIDRUG-RESISTANT;
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EID: 13744260022
PISSN: 00368075
EISSN: None
Source Type: Journal
DOI: 10.1126/science.1108379 Document Type: Short Survey |
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Times cited : (46)
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References (9)
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