Membrane targeting, shedding and protein interactions of brain acetylcholinesterase

Journal of Neurochemistry

Volumn 116, Issue 5, 2011, Pages 742-746

  Hicks, David ^a   John, Danielle ^a   Makova, Natalia Z ^a   Henderson, Zaineb ^a   Nalivaeva, Natalia N ^a,b   Turner, Anthony J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

Author keywords

acetylcholinesterase; Alzheimer disease; amyloid; lipid rafts; PRiMA; secretase; shedding

Indexed keywords

ACETYLCHOLINESTERASE; AMYLOID PRECURSOR PROTEIN; BUNGAROTOXIN RECEPTOR; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN;

ALZHEIMER DISEASE; ARTICLE; BRAIN MEMBRANE; CORPUS STRIATUM; ENZYME ACTIVITY; ERYTHROCYTE; FOREBRAIN; HUMAN; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; LIPID RAFT; MEMBRANE BINDING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN TARGETING;

ACETYLCHOLINESTERASE; ANIMALS; BRAIN; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; MEMBRANE MICRODOMAINS; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; NEURONS; RECEPTORS, NICOTINIC;

RATTUS;

EID: 79851507143     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.07032.x     Document Type: Article

References (36)

1. Alvarez A., Alarcón R., Opazo C., et al. (1998) Stable complexes involving acetylcholinesterase and amyloid-β peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils. J. Neurosci. 18, 3213-3223. (Pubitemid 28186014)
2. Appleyard M. E., (1992) Secreted acetylcholinesterase: non-classical aspects of a classical enzyme. Trends Neurosci. 15, 485-490.
3. Appleyard M. E., and, Smith A. D., (1987) Spontaneous and carbachol-evoked in vivo secretion of acetylcholinesterase from the hippocampus of the rat. Neurochem. Int. 11, 397-406. (Pubitemid 18017274)
4. Belyaev N. D., Nalivaeva N. N., Makova N. Z., and, Turner A. J., (2009) Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease. EMBO Rep. 10, 94-100.
5. Cordy J. M., Hussain I., Dingwall C., Hooper N. M., and, Turner A. J., (2003) Exclusively targeting β-secretase to lipid rafts by GPI-anchor addition up-regulates β-site processing of the amyloid precursor protein. Proc. Natl Acad. Sci. USA 100, 11735-11740. (Pubitemid 37206004)
6. Cordy J. M., Hooper N. M., and, Turner A. J., (2006) The involvement of lipid rafts in Alzheimer's disease. Mol. Membr. Biol. 23, 111-122.
7. Ehehalt R., Keller P., Haass C., Thiele C., and, Simons K., (2003) Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts. J. Cell Biol. 160, 113-123. (Pubitemid 36091721)
8. Geula C., and, Mesulam M., (1989) Special properties of cholinesterases in the cerebral cortex of Alzheimer's disease. Brain Res. 498, 185-189. (Pubitemid 19228181)
9. van Goor H., Melenhorst W. B., Turner A. J., and, Holgate S. T., (2009) Adamalysins in biology and disease. J. Pathol. 219, 277-286.
10. Greenfield S. A., Zimmermann M., and, Bond C. E., (2008) Non-hydrolytic functions of acetylcholinesterase. The significance of C-terminal peptides. FEBS J. 275, 604-611. (Pubitemid 351160966)
11. Grisaru D., Sternfeld M., Eldor A., Glick D., and, Soreq H., (1999) Structural roles of acetylcholinesterase variants in biology and pathology. Eur. J. Biochem. 264, 672-686. (Pubitemid 29437196)
12. Henderson Z., (1981) A projection from acetylcholinesterase-containing neurones in the diagonal band to the occipital cortex of the rat. Neuroscience 6, 1081-1088. (Pubitemid 11064212)
13. Henderson Z., (1989) Acetylcholinesterase on the dendrites of central cholinergic neurons: an electron microscopical study in the ferret. Neuroscience 28, 95-108. (Pubitemid 19026746)
14. Henderson Z., Boros A., Janzso G., Westwood A. J., Monyer H., and, Halasy K., (2005) Somato-dendritic nicotinic receptor responses recorded in vitro from the medial septal diagonal band complex of the rodent. J. Physiol. 562, 165-182. (Pubitemid 40207794)
15. Henderson Z., Matto N., John D., Nalivaeva N. N., and, Turner A. J., (2010) Co-localization of PRiMA with acetylcholinesterase in cholinergic neurons of rat brain: an immunocytochemical study. Brain Res. 1344, 34-42.
16. Inestrosa N. C., Alvarez A., Pérez C. A., Moreno R. D., Vicente M., Linker C., Casanueva O. I., Soto C., and, Garrido J., (1996) Acetylcholinesterase accelerates assembly of amyloid-β-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme. Neuron 16, 881-891. (Pubitemid 26124065)
17. Landgraf D., Barth M., Layer P. G., and, Sperling L. E., (2010) Acetylcholine as a possible signaling molecule in embryonic stem cells: studies on survival, proliferation and death. Chem. Biol. Interact. 187, 115-119.
18. SW mice. Brain Res. 977, 16-22. (Pubitemid 36638689)
19. Malatová Z., and, Marsala J., (1993) Cholinergic enzymes in spinal cord infarction. Biochemical and histochemical changes. Mol. Chem. Neuropathol. 19, 283-296. (Pubitemid 23241851)
20. Massoulié J., Bon S., Perrier N., and, Falasca C., (2005) The C-terminal peptides of acetylcholinesterase: cellular trafficking, oligomerization and functional anchoring. Chem. Biol. Interact. 157-158, 3-14. (Pubitemid 41757627)
21. Moral-Naranjo M. T., Montenegro M. F., Muñoz-Delgado E., Campoy F. J., and, Vidal C. J., (2010) The levels of both lipid rafts and raft-located acetylcholinesterase dimers increase in muscle of mice with muscular dystrophy by merosin deficiency. Biochim. Biophys. Acta 1802, 754-764.
22. Nalivaeva N. N., and, Turner A. J., (1999) Does acetylcholinesterase secretion involve an ADAMs-like metallosecretase? Lett. Peptide Sci. 6, 343-348. (Pubitemid 29462952)
23. Navaratnam D. S., Fernando F. S., Priddle J. D., Giles K., Clegg S. M., Pappin D. J., Craig I., and, Smith A. D., (2000) Hydrophobic protein that copurifies with human brain acetylcholinesterase: amino acid sequence, genomic organization, and chromosomal localization. J. Neurochem. 74, 2146-2153. (Pubitemid 30217672)
24. Pakaski M., Rakonczay Z., and, Kasa P., (2001) Reversible and irreversible acetylcholinesterase inhibitors cause changes in neuronal amyloid precursor protein processing and protein kinase C level in vitro. Neurochem. Int. 38, 219-226.
25. Perrier A. L., Massoulié J., and, Krejci E., (2002) PRiMA: the membrane anchor of acetylcholinesterase in the brain. Neuron 33, 275-285. (Pubitemid 34127759)
26. Ring S., Weyer S. W., Kilian S. B., et al. (2007) The secreted β-amyloid precursor protein ectodomain APPsα is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice. J. Neurosci. 27, 7817-7826. (Pubitemid 47093823)
27. Rodríguez-Ithurralde D., Maruri A., and, Rodríguez X., (1998) Motor neurone acetylcholinesterase release precedes neurotoxicity caused by systemic administration of excitatory amino acids and strychnine. J. Neurol. Sci. 160 (Suppl. 1), S80-S86. (Pubitemid 28522524)
28. Salas R., Main A., Gangitano D. A., Zimmerman G., Ben-Ari S., Soreq H., and, De Biasi M., (2008) Nicotine relieves anxiogenic-like behavior in mice that overexpress the read-through variant of acetylcholinesterase but not in wild-type mice. Mol. Pharmacol. 74, 1641-1648.
29. Schliebs R., and, Arendt T., (2006) The significance of the cholinergic system in the brain during aging and in Alzheimer's disease. J. Neural Transm. 113, 1625-1644. (Pubitemid 44657659)
30. Schweitzer E. S., (1993) Regulated and constitutive secretion of distinct molecular forms of acetylcholinesterase from PC12 cells. J. Cell Sci. 106, 731-740. (Pubitemid 23346786)
31. Small D. H., Michaelson S., and, Sberna G., (1996) Non-classical actions of cholinesterases: role in cellular differentiation, tumorigenesis and Alzheimer's disease. Neurochem. Int. 28, 453-483. (Pubitemid 26161318)
32. Small D. H., Maksel D., Kerr M. L., et al. (2007) The β-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the α7 nicotinic acetylcholine receptor. J. Neurochem. 101, 1527-1538. (Pubitemid 46848846)
33. Vetrivel K. S., and, Thinakaran G., (2010) Membrane rafts in Alzheimer's disease β-amyloid production. Biochim. Biophys. Acta 1801, 860-867.
34. Wang H. Y., Lee D. H., Davis C. B., and, Shank R. P., (2000) Amyloid peptide Aβ(1-42) binds selectively and with picomolar affinity to α7 nicotinic acetylcholine receptors. J. Neurochem. 75, 1155-1161. (Pubitemid 30660505)
35. Xie H. Q., Choi R. C., Leung K. W., Chen V. P., Chu G. K., and, Tsim K. W., (2009) Transcriptional regulation of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase in neuron: an inductive effect of neuron differentiation. Brain Res. 1265, 13-23.
36. Xie H. Q., Liang D., Leung K. W., Chen V. P., Zhu K. Y., Chan W. K., Choi R. C., Massoulié J., and, Tsim K. W., (2010) Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons. J. Biol. Chem. 285, 11537-11546.