Synthesis and characterisation of two novel proton transfer compounds and their inhibition studies on carbonic anhydrase isoenzymes

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 26, Issue 1, 2011, Pages 104-114

  Yenikaya, Cengiz ^a   Sarí, Musa ^b   Bülbül, Metin ^a   Ilkimen, Halil ^a   Çínar, Burcu ^a   Büyükgüngör, Orhan ^c  

^a DUMLUPINAR UNIVERSITY   (Turkey)

^b GAZI UNIVERSITY   (Turkey)

^c ONDOKUZ MAYIS UNIVERSITY   (Turkey)

Author keywords

2,4 dichloro 5 sulphamoylbenzoic acid; 2 amino 3 methylpyridine; crystal structure; ethylenediamine; glaucoma; inhibition; proton transfer

Indexed keywords

2 AMINO 3 METHYLPYRIDINE (2 AMINO 3 PICOLINE); 2 AMINO 3 METHYLPYRIDINIUM 2,4 DICHLORO 5 SULPHAMOYLBENZOATE; ACETAZOLAMIDE; ANTIGLAUCOMA AGENT; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; ETHANE 1,2 DIAMINIUM 2,4 DICHLORO 5 SULPHAMOYLBENZOATE; LASAMIDE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; ERYTHROCYTE MEMBRANE; HYDROGEN BOND; IC 50; IN VITRO STUDY; INFRARED SPECTROSCOPY; PRIORITY JOURNAL; PROTON TRANSPORT; X RAY DIFFRACTION;

ACETAZOLAMIDE; AMINOPYRIDINES; ANIMALS; BENZOATES; CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CRYSTALLOGRAPHY, X-RAY; ENZYME ASSAYS; ERYTHROCYTES; ETHYLENEDIAMINES; GLAUCOMA; HUMANS; INHIBITORY CONCENTRATION 50; ISOENZYMES; KINETICS; MICE; PICOLINES; PROTONS; SPECTRUM ANALYSIS;

EID: 79851480228     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756361003733639     Document Type: Article

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