Ultrastructural variations in platelets and platelet mitochondria: A novel feature in amyotrophic lateral sclerosis

Ultrastructural Pathology

Volumn 35, Issue 2, 2011, Pages 52-59

  Shrivastava, Mohita ^a   Das, Taposh K ^a   Behari, Madhuri ^a,b   Pati, Uttam ^a,b   Vivekanandhan, S ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

ALS; Platelet mitochondria; Platelets; TEM; Ultrastructure

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BLOOD; CASE CONTROL STUDY; FEMALE; HUMAN; INDIA; MALE; MIDDLE AGED; MITOCHONDRION; PATHOLOGY; PHLEBOTOMY; THROMBOCYTE; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

AMYOTROPHIC LATERAL SCLEROSIS; BLOOD PLATELETS; CASE-CONTROL STUDIES; FEMALE; HUMANS; INDIA; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MIDDLE AGED; MITOCHONDRIA; PHLEBOTOMY;

EID: 79851474876     PISSN: 01913123     EISSN: 15210758     Source Type: Journal    
DOI: 10.3109/01913123.2010.541985     Document Type: Article

References (43)

1. Swerdlow RH, Parks JK, Cassarino DS, et al. Mitochondria in sporadic amyotrophic lateral sclerosis. Exp Neurol. 1998b; 153:135-142. (Pubitemid 28452305)
2. Beal MF. Mitochondria and the pathogenesis of ALS. Brain. 2000 Jul; 123 (7):1291-1292. (Pubitemid 30420932)
3. Shi C, et al. Effects of ageing and Alzheimer's disease on mitochondrial function of human platelets. Exp Gerontol. 2008; (43): 589-594.
4. Bos IW, Hoogland G, Meine Jansen CF, et al. Increasedglutamine synthetase but normal EAAT2 expression in platelets of ALS patients. Neurochem Int. 2006 Mar; 48(4):306-311. (Pubitemid 43177152)
5. Merlo Pich M, Bovina C, Formiggini G, et al. Inhibitor sensitivity of respiratory complex I in human platelets, a possible biomarker of ageing. FEBS Lett. 1996; 380:176-178. (Pubitemid 26058753)
6. Xu J, Shi Ch, Li Q, Wu J, Forster EL, Yew DT. Mitochondrial dysfunction in platelets and hippocampi of senescenceaccelerated mice. J Bioenerg Biomembr. 2007; 39:195-202. (Pubitemid 46870549)
7. Ferrarese C, Sala G, Riva R, et al; Italian ALS Study Group. Decreased platelet glutamate uptake in patients with amyotrophic lateral sclerosis. Neurology. 2001 Jan 23; 56(2):270-272. (Pubitemid 32095377)
8. Swerdlow RH. Mitochondria in cybrids containing mtDNA from persons with mitochondriopathies. J Neurosci Res. 2007; 85:3416-3428. (Pubitemid 350058530)
9. Swerdlow RH, Parks JK, Cassarino DS, et al. Cybrids in Alzheimer's disease:a cellular model of the disease? Neurology. 1997; 49:918-925. (Pubitemid 27456066)
10. Kile BT. The role of the intrinsic apoptotic pathway in platelet life and death. J Thromb Haemost. 2009 Jul; 7 (Suppl): 1:214-217.
11. Perrotta PL, Perrotta CL, Snyder EL. Apoptotic activity in stored human platelets. Transfusion. 2003 Apr; 43(4):526-535. (Pubitemid 36428337)
12. Rothstein JD, Martin LJ, Kuncl RW. Decreased glutamate transport by the brain and spinal cord in amyotropic lateral sclerosis. N Engl J Med. 1992;236:1464-1468
13. Rothstein J D. Excitotoxicity and neurodegeneration in amyotrophic lateral sclerosis. Clin Neurosci. 1996; 3: 348-359.
14. Brighina L, Sala G, Ceresa C, Tremolizzo L, Ferrarese C. Recent advances in the therapy of amyotrophic lateral sclerosis: focus on excitotoxicity. Funct Neurol. 2001; 16(4 Suppl):189-202. (Pubitemid 34295911)
15. Hoogland G, Bos IW, Kupper F, et al. Thrombin-stimulated glutamate uptake in human platelets is predominantly mediated by the glial glutamate transporter EAAT2. Neurochem Int. 2005 Dec; 47(7): 499-506. (Pubitemid 41266880)
16. Lin KH, Chang HC, Lu WJ, et al. Comparison of the relative activities of inducing platelet apoptosis stimulated by various platelet-activating agents. Platelets. 2009 Dec; 20(8):575-581.
17. Born GVR. Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature.194:927-929.
18. Fritsma GA. Evaluation of hemostasis. In Rodak BF (editor). Hematology Clinical Principles and Applications, 2nd ed. Philadelphia: WB Saunders; 2002, p. 738.
19. Brooks BR. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases and the El Escorial 'Clinical Limits of Amyotrophic Lateral Sclerosis' workshop contributors. J Neurol Sci. 1994; 124:96-107 Suppl.
20. Chaudhuri KR, Crump S, al-Sarraj S, Anderson V, Cavanagh J, Leigh PN. The validation of El Escorial criteria for the diagnosis of amyotrophic lateral sclerosis: a clinicopathological study. J Neurol Sci. 1995; 129:11-12.
21. Grimaud JA, Druget M, Peyrol S, Chevalier D. Collageimmuno-typing in human liver: light and electron microscope study. J Histochem Cytol. 1980; 28:1145-1151.
22. White JG. Electron microscopy methods for studying platelet structure and function. In: Gibbins M, Makaut-Smith, eds. Totown, NJ: Human Press; 2002: 47-64.
23. Parker WD, Boyson SJ, Parks JK. Electron transport chain abnormalities in idiopathic Parkinson's disease. Annals Neurol. 1989; 26:719-723. (Pubitemid 20011004)
24. Ferrick DA, et al. Advances in measuring cellular bioenergetics using extracellular flux. Drug Discov Today. 2008; 13:268-274.
25. Verhoeven AJ, Verhaar R, Gouwerok EG, de Korte D. The mitochondrial membrane potential in human platelets: a sensitive parameter for platelet quality. Transfusion. 2005 Jan;45(1):82-89.
26. Picker SM, Schneider V, Oustianskaia L, Gathof BS. Cell viability during platelet storage in correlation to cellular metabolism after different pathogen reduction technologies. Transfusion. 2009 Nov;49(11):2311-2318.
27. Bacman SR, Bradley WG, Moraes CT. Mitochondrial involvement in amyotrophic lateral sclerosis: trigger or target? Mol Neurobiol. 2006 Apr; 33(2):113-131. (Pubitemid 43780370)
28. Trimmer PA, Swerdlow RH, Parks JK, et al. Abnormal mitochondrial morphology in sporadic Parkinson's and Alzheimer's disease cybrid cell lines. Exp Neurol. 2000; 162:37-50. (Pubitemid 30170099)
29. Kiktenko AI, Zlobina GP, Brusov OS, Zakharova MN. Structure of peripheral blood platelets surface in patients with amyotrophic lateral sclerosis and multiple sclerosis. Zh Nevrol Psikhiatr Im S S Korsakova. 2005; 105(3): 40-42. (Pubitemid 44077232)
30. Pretorius E. The role of platelet and fibrin ultrastructure in identifying disease patterns. Pathophysiol Haemost Thromb. 2007-08;36:251-258.
31. Mendoza-Sotelo J, Torner C, Alvarado-Vásquez N, et al. Ultrastructural changes and immunolocalization of P-selectin in platelets from patients with major depression. Psychiatry Res. 2010 Apr 30;176(2-3):179-182.
32. Windus DW, Atkinson R, Santoro S. The effects of hemodialysis on platelet activation with new and reprocessed regenerated cellulose dialyzers. Am J Kidney Dis. 1996; 27:387-393. (Pubitemid 26075848)
33. Elshamaa MF, Elghoroury EA, Amira Helmy A. Intradialytic and postdialytic platelet activation, increased platelet phosphatidylserine exposure and ultrastructural changes in platelets in children with chronic uremia. Blood Coagul Fibrin. 2009, 20:230-239.
34. Beal MF. Mechanisms of excitotoxicity in neurologic diseases. FASEB J. 1992 Dec;6(15):3338-3344. (Pubitemid 23007098)
35. Curti D, Malaspina A, Facchetti G, et al. Amyotrophic lateral sclerosis: oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes. Neurology. 1996; 47: 1060-1064.
36. Beal MF. Mitochondria, free radicals, and neurodegeneration. Curr Opin Neurobiol. 1996 Oct;6(5):661-666.
37. Barber SC, Mead RJ, Shaw PJ. Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target. Biochim Biophys Acta. 2006 Nov-Dec; 1762(11-12):1051-1067. (Pubitemid 44750575)
38. Borthwick GM, Johnson MA, Ince PG, Shaw PJ, Turnbull DM. Mitochondrial enzyme activity in amyotrophic lateral sclerosis: implications for the role of mitochondria in neuronal cell death. Ann Neurol. 1999 Nov; 46(5):787-790. (Pubitemid 29518143)
39. Friedlander RM. Apoptosis and caspases in neurodegenerative diseases. N Engl J Med. 2003 Apr; 348(14):1365-1375. Review. (Pubitemid 36384105)
40. Bradley LJ, Taanman JW, Kallis C, Orrell RW. Increased sensitivity of myoblasts to oxidative stress in amyotrophic lateral sclerosis peripheral tissues. Exp Neurol. 2009 Jul; 218(1):92-97.
41. Wong PC, Pardo CA, Borchelt DR, et al. An adverse property of a familiar ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron. 1995; 14: 1105-1116.
42. Kong J, Xu Z. Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. J Neurosci. 1998; 18: 3241-3250. (Pubitemid 28186017)
43. Menzies FM, Ince PG, Shaw PJ. Mitochondrial involvement in amyotrophic lateral sclerosis. Neurochem Int. 2002 May; 40(6):543-551. (Pubitemid 34159155)