Increased sensitivity of myoblasts to oxidative stress in amyotrophic lateral sclerosis peripheral tissues

Experimental Neurology

Volumn 218, Issue 1, 2009, Pages 92-97

  Bradley, Lloyd J ^a   Taanman, Jan Willem ^a   Kallis, Constantinos ^a,b   Orrell, Richard W ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Amyotrophic lateral sclerosis; Cybrid; Fibroblast; Mitochondria; Muscle; Myoblast; Oxidative stress; SOD1

Indexed keywords

ACONITATE HYDRATASE; CASPASE 3; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA; PARAQUAT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL METABOLISM; CELL REGENERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYBRID; DISEASE DURATION; ENZYME ACTIVITY; FEMALE; FIBROBLAST CULTURE; GENE DELETION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MITOCHONDRIAL RESPIRATION; MITOSIS; MOTONEURON; MUSCLE TISSUE; MYOBLAST; NERVOUS TISSUE; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESPIRATORY CHAIN; SOUTHERN BLOTTING; SPECTROPHOTOMETRY;

ACONITATE HYDRATASE; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AMYOTROPHIC LATERAL SCLEROSIS; CASPASE 3; CELLS, CULTURED; DNA, MITOCHONDRIAL; FEMALE; HUMANS; MALE; MIDDLE AGED; MITOCHONDRIA; MUSCLES; MYOBLASTS; NADH, NADPH OXIDOREDUCTASES; OXIDATIVE STRESS; PARAQUAT; SPECTROPHOTOMETRY; SUPEROXIDE DISMUTASE; YOUNG ADULT;

EID: 67349115326     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2009.04.007     Document Type: Article

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