메뉴 건너뛰기




Volumn 50, Issue 4, 2011, Pages 228-238

Microhomologies and topoisomerase II consensus sequences identified near the breakpoint junctions of the recurrent t(7;21)(p22;q22) translocation in acute myeloid leukemia

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); TRANSCRIPTION FACTOR RUNX1;

EID: 79851472433     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20848     Document Type: Article
Times cited : (16)

References (53)
  • 1
    • 29444434887 scopus 로고    scopus 로고
    • Causes of oncogenic chromosomal translocation
    • Aplan PD. 2006a. Causes of oncogenic chromosomal translocation. Trends Genet 22: 46-55.
    • (2006) Trends Genet , vol.22 , pp. 46-55
    • Aplan, P.D.1
  • 2
    • 33748178469 scopus 로고    scopus 로고
    • Chromosomal translocations involving the MLL gene: Molecular mechanisms
    • Aplan PD. 2006b. Chromosomal translocations involving the MLL gene: Molecular mechanisms. DNA Repair (Amst) 5: 1265-1272.
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1265-1272
    • Aplan, P.D.1
  • 3
    • 0030012114 scopus 로고    scopus 로고
    • Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors
    • Aplan PD, Chervinsky DS, Stanulla M, Burhans WC. 1996. Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors. Blood 87: 2649-2658.
    • (1996) Blood , vol.87 , pp. 2649-2658
    • Aplan, P.D.1    Chervinsky, D.S.2    Stanulla, M.3    Burhans, W.C.4
  • 4
    • 41649109612 scopus 로고    scopus 로고
    • Identification of the novel AML1 fusion partner gene, LAF4, a fusion partner of MLL, in childhood T-cell acute lymphoblastic leukemia with t(2;21)(q11;q22) by bubble PCR method for cDNA
    • Chinen Y, Taki T, Nishida K, Shimizu D, Okuda T, Yoshida N, Kobayashi C, Koike K, Tsuchida M, Hayashi Y, Taniwaki M. 2008. Identification of the novel AML1 fusion partner gene, LAF4, a fusion partner of MLL, in childhood T-cell acute lymphoblastic leukemia with t(2;21)(q11;q22) by bubble PCR method for cDNA. Oncogene 27: 2249-2256.
    • (2008) Oncogene , vol.27 , pp. 2249-2256
    • Chinen, Y.1    Taki, T.2    Nishida, K.3    Shimizu, D.4    Okuda, T.5    Yoshida, N.6    Kobayashi, C.7    Koike, K.8    Tsuchida, M.9    Hayashi, Y.10    Taniwaki, M.11
  • 5
    • 38849110179 scopus 로고    scopus 로고
    • Targeting ubiquitin specific proteases for drug discovery
    • Daviet L, Colland F. 2008. Targeting ubiquitin specific proteases for drug discovery. Biochimie 90: 270-283.
    • (2008) Biochimie , vol.90 , pp. 270-283
    • Daviet, L.1    Colland, F.2
  • 7
    • 33747892853 scopus 로고    scopus 로고
    • Topoisomerase II and the etiology of chromosomal translocations
    • Felix CA, Kolaris CP, Osheroff N. 2006. Topoisomerase II and the etiology of chromosomal translocations. DNA Repair (Amst) 5: 1093-1108.
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1093-1108
    • Felix, C.A.1    Kolaris, C.P.2    Osheroff, N.3
  • 9
    • 34848831463 scopus 로고    scopus 로고
    • Molecular characterization of acute myeloid leukemia and its impact on treatment
    • Frankfurt O, Licht JD, Tallman MS. 2007. Molecular characterization of acute myeloid leukemia and its impact on treatment. Curr Opin Oncol 19: 635-649.
    • (2007) Curr Opin Oncol , vol.19 , pp. 635-649
    • Frankfurt, O.1    Licht, J.D.2    Tallman, M.S.3
  • 12
    • 63649086487 scopus 로고    scopus 로고
    • Targeting the ubiquitin system in cancer therapy
    • Hoeller D, Dikic I. 2009. Targeting the ubiquitin system in cancer therapy. Nature 458: 438-444.
    • (2009) Nature , vol.458 , pp. 438-444
    • Hoeller, D.1    Dikic, I.2
  • 13
    • 79851493730 scopus 로고
    • International Standing Committee on Human Cytogenetic Nomenclature, ISCN 1995: An international system for human cytogenetic nomenclature (1995): Recommendations of the International Standing Committee on Human Cytogenetic Nomenclature, Memphis, Tennessee, USA, October 9-13, 1994. Basel: Karger.
    • International Standing Committee on Human Cytogenetic Nomenclature, Mitelman F. 1995. ISCN 1995: An international system for human cytogenetic nomenclature (1995): Recommendations of the International Standing Committee on Human Cytogenetic Nomenclature, Memphis, Tennessee, USA, October 9-13, 1994. Basel: Karger.
    • (1995)
    • Mitelman, F.1
  • 14
    • 0037129369 scopus 로고    scopus 로고
    • The t(3;21) fusion product, AML1/Evi-1 blocks AML1-induced transactivation by recruiting CtBP
    • Izutsu K, Kurokawa M, Imai Y, Ichikawa M, Asai T, Maki K, Mitani K, Hirai H. 2002. The t(3;21) fusion product, AML1/Evi-1 blocks AML1-induced transactivation by recruiting CtBP. Oncogene 21: 2695-2703.
    • (2002) Oncogene , vol.21 , pp. 2695-2703
    • Izutsu, K.1    Kurokawa, M.2    Imai, Y.3    Ichikawa, M.4    Asai, T.5    Maki, K.6    Mitani, K.7    Hirai, H.8
  • 15
    • 68749109365 scopus 로고    scopus 로고
    • RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation
    • Kuo MC, Liang DC, Huang CF, Shih YS, Wu JH, Lin TL, Shih LY. 2009. RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation. Leukemia 23: 1426-1431.
    • (2009) Leukemia , vol.23 , pp. 1426-1431
    • Kuo, M.C.1    Liang, D.C.2    Huang, C.F.3    Shih, Y.S.4    Wu, J.H.5    Lin, T.L.6    Shih, L.Y.7
  • 16
    • 62449178451 scopus 로고    scopus 로고
    • Transforming activity of AML1-ETO is independent of CBFβ and ETO interaction but requires formation of homo-oligomeric complexes
    • Kwok C, Zeisig BB, Qiu J, Dong S, So CW. 2009. Transforming activity of AML1-ETO is independent of CBFβ and ETO interaction but requires formation of homo-oligomeric complexes. Proc Natl Acad Sci USA 106: 2853-2858.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 2853-2858
    • Kwok, C.1    Zeisig, B.B.2    Qiu, J.3    Dong, S.4    So, C.W.5
  • 18
    • 0035859820 scopus 로고    scopus 로고
    • Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation
    • Lovett BD, Lo Nigro L, Rappaport EF, Blair IA, Osheroff N, Zheng N, Megonigal MD, Williams WR, Nowell PC, Felix CA. 2001. Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation. Proc Natl Acad Sci USA 98: 9802-9807.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9802-9807
    • Lovett, B.D.1    Lo Nigro, L.2    Rappaport, E.F.3    Blair, I.A.4    Osheroff, N.5    Zheng, N.6    Megonigal, M.D.7    Williams, W.R.8    Nowell, P.C.9    Felix, C.A.10
  • 19
    • 54949084641 scopus 로고    scopus 로고
    • Role of the RUNX1-EVI1 fusion gene in leukemogenesis
    • Maki K, Yamagata T, Mitani K. 2008. Role of the RUNX1-EVI1 fusion gene in leukemogenesis. Cancer Sci 99: 1878-1883.
    • (2008) Cancer Sci , vol.99 , pp. 1878-1883
    • Maki, K.1    Yamagata, T.2    Mitani, K.3
  • 21
    • 33947581390 scopus 로고    scopus 로고
    • The impact of translocations and gene fusions on cancer causation
    • Mitelman F, Johansson B, Mertens F. 2007. The impact of translocations and gene fusions on cancer causation. Nat Rev Cancer 7: 233-245.
    • (2007) Nat Rev Cancer , vol.7 , pp. 233-245
    • Mitelman, F.1    Johansson, B.2    Mertens, F.3
  • 22
    • 34347338694 scopus 로고    scopus 로고
    • TEL-AML1 preleukemic activity requires the DNA binding domain of AML1 and the dimerization and corepressor binding domains of TEL
    • Morrow M, Samanta A, Kioussis D, Brady HJ, Williams O. 2007. TEL-AML1 preleukemic activity requires the DNA binding domain of AML1 and the dimerization and corepressor binding domains of TEL. Oncogene 26: 4404-4414.
    • (2007) Oncogene , vol.26 , pp. 4404-4414
    • Morrow, M.1    Samanta, A.2    Kioussis, D.3    Brady, H.J.4    Williams, O.5
  • 23
    • 34249340637 scopus 로고    scopus 로고
    • Chromosome aberrations, gene mutations and expression changes, and prognosis in adult acute myeloid leukemia
    • Mrozek K, Bloomfield CD. 2006. Chromosome aberrations, gene mutations and expression changes, and prognosis in adult acute myeloid leukemia. Hematology Am Soc Hematol Educ Program 169-177.
    • (2006) Hematology Am Soc Hematol Educ Program , pp. 169-177
    • Mrozek, K.1    Bloomfield, C.D.2
  • 25
    • 0028066779 scopus 로고
    • PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 β/CBF β proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells
    • Nuchprayoon I, Meyers S, Scott LM, Suzow J, Hiebert S, Friedman AD. 1994. PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 β/CBF β proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells. Mol Cell Biol 14: 5558-5568.
    • (1994) Mol Cell Biol , vol.14 , pp. 5558-5568
    • Nuchprayoon, I.1    Meyers, S.2    Scott, L.M.3    Suzow, J.4    Hiebert, S.5    Friedman, A.D.6
  • 28
    • 2942667930 scopus 로고    scopus 로고
    • Point mutations in the RUNX1/AML1 gene: Another actor in RUNX leukemia
    • Osato M. 2004. Point mutations in the RUNX1/AML1 gene: Another actor in RUNX leukemia. Oncogene 23: 4284-4296.
    • (2004) Oncogene , vol.23 , pp. 4284-4296
    • Osato, M.1
  • 30
    • 31444449609 scopus 로고    scopus 로고
    • A novel and cytogenetically cryptic t(7;21)(p22;q22) in acute myeloid leukemia results in fusion of RUNX1 with the ubiquitin-specific protease gene USP42
    • Paulsson K, Bekassy AN, Olofsson T, Mitelman F, Johansson B, Panagopoulos I. 2006. A novel and cytogenetically cryptic t(7;21)(p22;q22) in acute myeloid leukemia results in fusion of RUNX1 with the ubiquitin-specific protease gene USP42. Leukemia 20: 224-229.
    • (2006) Leukemia , vol.20 , pp. 224-229
    • Paulsson, K.1    Bekassy, A.N.2    Olofsson, T.3    Mitelman, F.4    Johansson, B.5    Panagopoulos, I.6
  • 31
    • 2942516037 scopus 로고    scopus 로고
    • The 8;21 translocation in leukemogenesis
    • Peterson LF, Zhang DE. 2004. The 8;21 translocation in leukemogenesis. Oncogene 23: 4255-4262.
    • (2004) Oncogene , vol.23 , pp. 4255-4262
    • Peterson, L.F.1    Zhang, D.E.2
  • 32
    • 65349182349 scopus 로고    scopus 로고
    • Overexpression of ZNF342 by juxtaposition with MPO promoter/enhancer in the novel translocation t(17;19)(q23; q13.32) in pediatric acute myeloid leukemia and analysis of ZNF342 expression in leukemia
    • Poland KS, Shardy DL, Azim M, Naeem R, Krance RA, Dreyer ZE, Neeley ES, Zhang N, Qiu YH, Kornblau SM, Plon SE. 2009. Overexpression of ZNF342 by juxtaposition with MPO promoter/enhancer in the novel translocation t(17;19)(q23; q13.32) in pediatric acute myeloid leukemia and analysis of ZNF342 expression in leukemia. Genes Chromosomes Cancer 48: 480-489.
    • (2009) Genes Chromosomes Cancer , vol.48 , pp. 480-489
    • Poland, K.S.1    Shardy, D.L.2    Azim, M.3    Naeem, R.4    Krance, R.A.5    Dreyer, Z.E.6    Neeley, E.S.7    Zhang, N.8    Qiu, Y.H.9    Kornblau, S.M.10    Plon, S.E.11
  • 35
    • 0037007115 scopus 로고    scopus 로고
    • Panhandle and reverse-panhandle PCR enable cloning of der(11) and der (other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6
    • Raffini LJ, Slater DJ, Rappaport EF, Lo Nigro L, Cheung NK, Biegel JA, Nowell PC, Lange BJ, Felix CA. 2002. Panhandle and reverse-panhandle PCR enable cloning of der(11) and der (other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6. Proc Natl Acad Sci USA 99: 4568-4573.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 4568-4573
    • Raffini, L.J.1    Slater, D.J.2    Rappaport, E.F.3    Lo Nigro, L.4    Cheung, N.K.5    Biegel, J.A.6    Nowell, P.C.7    Lange, B.J.8    Felix, C.A.9
  • 37
    • 43549086237 scopus 로고    scopus 로고
    • RUNX1 DNA-binding mutations and RUNX1-PRDM16 cryptic fusions in BCR-ABL+ leukemias are frequently associated with secondary trisomy 21 and may contribute to clonal evolution and imatinib resistance
    • Roche-Lestienne C, Deluche L, Corm S, Tigaud I, Joha S, Philippe N, Geffroy S, Lai JL, Nicolini FE, Preudhomme C. 2008. RUNX1 DNA-binding mutations and RUNX1-PRDM16 cryptic fusions in BCR-ABL+ leukemias are frequently associated with secondary trisomy 21 and may contribute to clonal evolution and imatinib resistance. Blood 111: 3735-3741.
    • (2008) Blood , vol.111 , pp. 3735-3741
    • Roche-Lestienne, C.1    Deluche, L.2    Corm, S.3    Tigaud, I.4    Joha, S.5    Philippe, N.6    Geffroy, S.7    Lai, J.L.8    Nicolini, F.E.9    Preudhomme, C.10
  • 38
    • 0032532643 scopus 로고    scopus 로고
    • CBFA2(AML1) translocations with novel partner chromosomes in myeloid leukemias: Association with prior therapy
    • Roulston D, Espinosa R, III, Nucifora G, Larson RA, Le Beau MM, Rowley JD. 1998. CBFA2(AML1) translocations with novel partner chromosomes in myeloid leukemias: Association with prior therapy. Blood 92: 2879-2885.
    • (1998) Blood , vol.92 , pp. 2879-2885
    • Roulston, D.1    Espinosa III, R.2    Nucifora, G.3    Larson, R.A.4    Le Beau, M.M.5    Rowley, J.D.6
  • 39
    • 0001760677 scopus 로고
    • Molecular Cloning: A Laboratory Manual
    • 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory. v.
    • Sambrook J, Fritsch EF, Maniatis T. 1989. Molecular Cloning: A Laboratory Manual, 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory. 3 v. pA8.9
    • (1989) , vol.3
    • Sambrook, J.1    Fritsch, E.F.2    Maniatis, T.3
  • 40
    • 0023902435 scopus 로고
    • A consensus sequence for cleavage by vertebrate DNA topoisomerase II
    • Spitzner JR, Muller MT. 1988. A consensus sequence for cleavage by vertebrate DNA topoisomerase II. Nucleic Acids Res 16: 5533-5556.
    • (1988) Nucleic Acids Res , vol.16 , pp. 5533-5556
    • Spitzner, J.R.1    Muller, M.T.2
  • 42
    • 53249123632 scopus 로고    scopus 로고
    • WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
    • World Health Organization. ., 4th ed. Lyon, France: International Agency for Research on Cancer
    • Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW. World Health Organization. 2008. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, 4th ed. Lyon, France: International Agency for Research on Cancer. 439 p.
    • (2008) , pp. 439
    • Swerdlow, S.H.1    Campo, E.2    Harris, N.L.3    Jaffe, E.S.4    Pileri, S.A.5    Stein, H.6    Thiele, J.7    Vardiman, J.W.8
  • 43
    • 0028998584 scopus 로고
    • Positive and negative regulation of granulocyte-macrophage colony-stimulating factor promoter activity by AML1-related transcription factor, PEBP2
    • Takahashi A, Satake M, Yamaguchi-Iwai Y, Bae SC, Lu J, Maruyama M, Zhang YW, Oka H, Arai N, Arai K, Ito Y. 1995. Positive and negative regulation of granulocyte-macrophage colony-stimulating factor promoter activity by AML1-related transcription factor, PEBP2. Blood 86: 607-616.
    • (1995) Blood , vol.86 , pp. 607-616
    • Takahashi, A.1    Satake, M.2    Yamaguchi-Iwai, Y.3    Bae, S.C.4    Lu, J.5    Maruyama, M.6    Zhang, Y.W.7    Oka, H.8    Arai, N.9    Arai, K.10    Ito, Y.11
  • 46
    • 33747888634 scopus 로고    scopus 로고
    • Modeling oncogenic translocations: Distinct roles for double-strand break repair pathways in translocation formation in mammalian cells
    • Weinstock DM, Richardson CA, Elliott B, Jasin M. 2006. Modeling oncogenic translocations: Distinct roles for double-strand break repair pathways in translocation formation in mammalian cells. DNA Repair (Amst) 5: 1065-1074.
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1065-1074
    • Weinstock, D.M.1    Richardson, C.A.2    Elliott, B.3    Jasin, M.4
  • 47
    • 0346753588 scopus 로고    scopus 로고
    • Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing
    • Whitmarsh RJ, Saginario C, Zhuo Y, Hilgenfeld E, Rappaport EF, Megonigal MD, Carroll M, Liu M, Osheroff N, Cheung NK, Slater DJ, Ried T, Knutsen T, Blair IA, Felix CA. 2003. Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing. Oncogene 22: 8448-8459.
    • (2003) Oncogene , vol.22 , pp. 8448-8459
    • Whitmarsh, R.J.1    Saginario, C.2    Zhuo, Y.3    Hilgenfeld, E.4    Rappaport, E.F.5    Megonigal, M.D.6    Carroll, M.7    Liu, M.8    Osheroff, N.9    Cheung, N.K.10    Slater, D.J.11    Ried, T.12    Knutsen, T.13    Blair, I.A.14    Felix, C.A.15
  • 49
    • 59649122714 scopus 로고    scopus 로고
    • RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leukemogenesis
    • Yan M, Ahn EY, Hiebert SW, Zhang DE. 2009. RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leukemogenesis. Blood 113: 883-886.
    • (2009) Blood , vol.113 , pp. 883-886
    • Yan, M.1    Ahn, E.Y.2    Hiebert, S.W.3    Zhang, D.E.4
  • 51
    • 0027984233 scopus 로고
    • Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1)
    • Zhang DE, Fujioka K, Hetherington CJ, Shapiro LH, Chen HM, Look AT, Tenen DG. 1994. Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1). Mol Cell Biol 14: 8085-8095.
    • (1994) Mol Cell Biol , vol.14 , pp. 8085-8095
    • Zhang, D.E.1    Fujioka, K.2    Hetherington, C.J.3    Shapiro, L.H.4    Chen, H.M.5    Look, A.T.6    Tenen, D.G.7
  • 52
    • 33747873409 scopus 로고    scopus 로고
    • Chromatin structural elements and chromosomal translocations in leukemia
    • Zhang Y, Rowley JD. 2006. Chromatin structural elements and chromosomal translocations in leukemia. DNA Repair (Amst) 5: 1282-1297.
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1282-1297
    • Zhang, Y.1    Rowley, J.D.2
  • 53
    • 0037022636 scopus 로고    scopus 로고
    • Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia
    • Zhang Y, Strissel P, Strick R, Chen J, Nucifora G, Le Beau MM, Larson RA, Rowley JD. 2002. Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia. Proc Natl Acad Sci USA 99: 3070-3075.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 3070-3075
    • Zhang, Y.1    Strissel, P.2    Strick, R.3    Chen, J.4    Nucifora, G.5    Le Beau, M.M.6    Larson, R.A.7    Rowley, J.D.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.