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Volumn 33, Issue 8, 2009, Pages 1082-1088

Cluster analysis of genomic ETV6-RUNX1 (TEL-AML1) fusion sites in childhood acute lymphoblastic leukemia

Author keywords

Childhood ALL; Chromosomal translocations; Cluster analysis; ETV6 RUNX1; Genomic fusion sites; TEL AML1

Indexed keywords

TRANSCRIPTION FACTOR ETV6; TRANSCRIPTION FACTOR RUNX1;

EID: 67349202133     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2008.11.001     Document Type: Article
Times cited : (19)

References (43)
  • 1
    • 0030742017 scopus 로고    scopus 로고
    • Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials. Associazione Italiana Ematologia Oncologia Pediatrica and the Berlin-Frankfurt-Munster Study Group
    • Borkhardt A., Cazzaniga G., Viehmann S., Valsecchi M.G., Ludwig W.D., Burci L., et al. Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials. Associazione Italiana Ematologia Oncologia Pediatrica and the Berlin-Frankfurt-Munster Study Group. Blood 90 (1997) 571-577
    • (1997) Blood , vol.90 , pp. 571-577
    • Borkhardt, A.1    Cazzaniga, G.2    Viehmann, S.3    Valsecchi, M.G.4    Ludwig, W.D.5    Burci, L.6
  • 2
    • 0141634051 scopus 로고    scopus 로고
    • Origins of chromosome translocations in childhood leukaemia
    • Greaves M.F., and Wiemels J. Origins of chromosome translocations in childhood leukaemia. Nat Rev Cancer 3 (2003) 639-649
    • (2003) Nat Rev Cancer , vol.3 , pp. 639-649
    • Greaves, M.F.1    Wiemels, J.2
  • 3
    • 2942682886 scopus 로고    scopus 로고
    • Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia
    • Zelent A., Greaves M., and Enver T. Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia. Oncogene 23 (2004) 4275-4283
    • (2004) Oncogene , vol.23 , pp. 4275-4283
    • Zelent, A.1    Greaves, M.2    Enver, T.3
  • 6
    • 0033178875 scopus 로고    scopus 로고
    • Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero
    • Wiemels J.L., Ford A.M., Van Wering E.R., Postma A., and Greaves M. Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero. Blood 94 (1999) 1057-1062
    • (1999) Blood , vol.94 , pp. 1057-1062
    • Wiemels, J.L.1    Ford, A.M.2    Van Wering, E.R.3    Postma, A.4    Greaves, M.5
  • 9
    • 38349183668 scopus 로고    scopus 로고
    • Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia
    • Hong D., Gupta R., Ancliff P., Atzberger A., Brown J., Soneji S., et al. Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia. Science 319 (2008) 336-339
    • (2008) Science , vol.319 , pp. 336-339
    • Hong, D.1    Gupta, R.2    Ancliff, P.3    Atzberger, A.4    Brown, J.5    Soneji, S.6
  • 10
    • 0037062496 scopus 로고    scopus 로고
    • Chromosome translocations and covert leukemic clones are generated during normal fetal development
    • Mori H., Colman S.M., Xiao Z., Ford A.M., Healy L.E., Donaldson C., et al. Chromosome translocations and covert leukemic clones are generated during normal fetal development. Proc Natl Acad Sci USA 99 (2002) 8242-8247
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8242-8247
    • Mori, H.1    Colman, S.M.2    Xiao, Z.3    Ford, A.M.4    Healy, L.E.5    Donaldson, C.6
  • 11
    • 0031011855 scopus 로고    scopus 로고
    • DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis
    • Stanulla M., Wang J., Chervinsky D.S., Thandla S., and Aplan P.D. DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis. Mol Cell Biol 17 (1997) 4070-4079
    • (1997) Mol Cell Biol , vol.17 , pp. 4070-4079
    • Stanulla, M.1    Wang, J.2    Chervinsky, D.S.3    Thandla, S.4    Aplan, P.D.5
  • 12
    • 0030012114 scopus 로고    scopus 로고
    • Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors
    • Aplan P.D., Chervinsky D.S., Stanulla M., and Burhans W.C. Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors. Blood 87 (1996) 2649-2658
    • (1996) Blood , vol.87 , pp. 2649-2658
    • Aplan, P.D.1    Chervinsky, D.S.2    Stanulla, M.3    Burhans, W.C.4
  • 13
    • 0035859820 scopus 로고    scopus 로고
    • Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation
    • Lovett B.D., Lo Nigro L., Rappaport E.F., Blair I.A., Osheroff N., Zheng N., et al. Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation. Proc Natl Acad Sci USA 98 (2001) 9802-9807
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9802-9807
    • Lovett, B.D.1    Lo Nigro, L.2    Rappaport, E.F.3    Blair, I.A.4    Osheroff, N.5    Zheng, N.6
  • 14
    • 18744372705 scopus 로고    scopus 로고
    • Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukaemia
    • Wiemels J.L., Leonard B.C., Wang Y., Segal M.R., Hunger S.P., Smith M.T., et al. Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukaemia. Proc Natl Acad Sci USA 99 (2002) 15101-15106
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15101-15106
    • Wiemels, J.L.1    Leonard, B.C.2    Wang, Y.3    Segal, M.R.4    Hunger, S.P.5    Smith, M.T.6
  • 15
    • 0032757710 scopus 로고    scopus 로고
    • Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukaemia
    • van Dongen J.J., Macintyre E.A., Gabert J.A., Delabesse E., Rossi V., Saglio G., et al. Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukaemia. Leukemia 13 (1999) 1901-1928
    • (1999) Leukemia , vol.13 , pp. 1901-1928
    • van Dongen, J.J.1    Macintyre, E.A.2    Gabert, J.A.3    Delabesse, E.4    Rossi, V.5    Saglio, G.6
  • 16
    • 0037866469 scopus 로고    scopus 로고
    • Late relapses evolve from slow-responding subclones in t(12;21)-positive acute lymphoblastic leukemia: evidence for the persistence of a preleukemic clone
    • Konrad M., Metzler M., Panzer S., Ostreicher I., Peham M., Repp R., et al. Late relapses evolve from slow-responding subclones in t(12;21)-positive acute lymphoblastic leukemia: evidence for the persistence of a preleukemic clone. Blood 101 (2003) 3635-3640
    • (2003) Blood , vol.101 , pp. 3635-3640
    • Konrad, M.1    Metzler, M.2    Panzer, S.3    Ostreicher, I.4    Peham, M.5    Repp, R.6
  • 17
    • 33744481524 scopus 로고    scopus 로고
    • Minimal residual disease analysis in children with t(12;21)-positive acute lymphoblastic leukemia: comparison of Ig/TCR rearrangements and the genomic fusion gene
    • Metzler M., Mann G., Monschein U., Lodzinski M., Gall C., Flohr T., et al. Minimal residual disease analysis in children with t(12;21)-positive acute lymphoblastic leukemia: comparison of Ig/TCR rearrangements and the genomic fusion gene. Haematologica 91 (2006) 683-686
    • (2006) Haematologica , vol.91 , pp. 683-686
    • Metzler, M.1    Mann, G.2    Monschein, U.3    Lodzinski, M.4    Gall, C.5    Flohr, T.6
  • 18
    • 0032740763 scopus 로고    scopus 로고
    • Molecular analysis of chromosomal breakpoints in three examples of chromosomal translocation involving the TEL gene
    • Romana S., Poirel H., Della Valle V., Mauchauffe M., Busson-Le Coniat M., Berger R., et al. Molecular analysis of chromosomal breakpoints in three examples of chromosomal translocation involving the TEL gene. Leukemia 13 (1999) 1754-1759
    • (1999) Leukemia , vol.13 , pp. 1754-1759
    • Romana, S.1    Poirel, H.2    Della Valle, V.3    Mauchauffe, M.4    Busson-Le Coniat, M.5    Berger, R.6
  • 19
    • 0032960839 scopus 로고    scopus 로고
    • ETV6-AML1 translocation breakpoints cluster near a purine/pyrimidine repeat region in the ETV6 gene
    • Thandla S.P., Ploski J.E., Raza-Egilmez S.Z., Chhalliyil P.P., Block A.W., de Jong P.J., et al. ETV6-AML1 translocation breakpoints cluster near a purine/pyrimidine repeat region in the ETV6 gene. Blood 93 (1999) 293-299
    • (1999) Blood , vol.93 , pp. 293-299
    • Thandla, S.P.1    Ploski, J.E.2    Raza-Egilmez, S.Z.3    Chhalliyil, P.P.4    Block, A.W.5    de Jong, P.J.6
  • 20
    • 0033566892 scopus 로고    scopus 로고
    • Structure and possible mechanisms of TEL-AML1 gene fusions in childhood acute lymphoblastic leukemia
    • Wiemels J.L., and Greaves M. Structure and possible mechanisms of TEL-AML1 gene fusions in childhood acute lymphoblastic leukemia. Cancer Res 59 (1999) 4075-4082
    • (1999) Cancer Res , vol.59 , pp. 4075-4082
    • Wiemels, J.L.1    Greaves, M.2
  • 23
    • 0344838398 scopus 로고    scopus 로고
    • Prenatal origin of TEL-AML1-positive acute lymphoblastic leukemia in children born in California
    • McHale C.M., Wiemels J.L., Zhang L., Ma X., Buffler P.A., Guo W., et al. Prenatal origin of TEL-AML1-positive acute lymphoblastic leukemia in children born in California. Genes Chromosomes Cancer 37 (2003) 36-43
    • (2003) Genes Chromosomes Cancer , vol.37 , pp. 36-43
    • McHale, C.M.1    Wiemels, J.L.2    Zhang, L.3    Ma, X.4    Buffler, P.A.5    Guo, W.6
  • 24
    • 0043264447 scopus 로고    scopus 로고
    • Translocation and gross deletion breakpoints in human inherited disease and cancer I: nucleotide composition and recombination-associated motifs
    • Abeysinghe S.S., Chuzhanova N., Krawczak M., Ball E.V., and Cooper D.N. Translocation and gross deletion breakpoints in human inherited disease and cancer I: nucleotide composition and recombination-associated motifs. Hum Mutat 22 (2003) 229-244
    • (2003) Hum Mutat , vol.22 , pp. 229-244
    • Abeysinghe, S.S.1    Chuzhanova, N.2    Krawczak, M.3    Ball, E.V.4    Cooper, D.N.5
  • 25
    • 0036489044 scopus 로고    scopus 로고
    • Clustering of translocation breakpoints
    • Segal M.R., and Wiemels J.L. Clustering of translocation breakpoints. J Am Stat Assoc 97 (2002) 66-76
    • (2002) J Am Stat Assoc , vol.97 , pp. 66-76
    • Segal, M.R.1    Wiemels, J.L.2
  • 26
    • 67349084403 scopus 로고    scopus 로고
    • Kulldorff M, Information Management Services, Inc. SaTScanTM v7.0: software for the spatial and space-time scan statistics. http://www.satscan.org/; 2006.
    • Kulldorff M, Information Management Services, Inc. SaTScanTM v7.0: software for the spatial and space-time scan statistics. http://www.satscan.org/; 2006.
  • 27
    • 0001268552 scopus 로고
    • A reliable data-based bandwidth selection method for kernel density estimation
    • Sheather S.J., and Jones M.C. A reliable data-based bandwidth selection method for kernel density estimation. J R Stat Soc Ser B 53 (1991) 683-690
    • (1991) J R Stat Soc Ser B , vol.53 , pp. 683-690
    • Sheather, S.J.1    Jones, M.C.2
  • 28
    • 0037092955 scopus 로고    scopus 로고
    • In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia
    • Wiemels J.L., Xiao Z., Buffler P.A., Maia A.T., Ma X., Dicks B.M., et al. In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia. Blood 99 (2002) 3801-3805
    • (2002) Blood , vol.99 , pp. 3801-3805
    • Wiemels, J.L.1    Xiao, Z.2    Buffler, P.A.3    Maia, A.T.4    Ma, X.5    Dicks, B.M.6
  • 29
    • 0036778597 scopus 로고    scopus 로고
    • The role of Alu repeat clusters as mediators of recurrent chromosomal aberrations in tumors
    • Kolomietz E., Meyn M.S., Pandita A., and Squire J.A. The role of Alu repeat clusters as mediators of recurrent chromosomal aberrations in tumors. Genes Chromosomes Cancer 35 (2002) 97-112
    • (2002) Genes Chromosomes Cancer , vol.35 , pp. 97-112
    • Kolomietz, E.1    Meyn, M.S.2    Pandita, A.3    Squire, J.A.4
  • 30
    • 0031898431 scopus 로고    scopus 로고
    • The BCR gene recombines preferentially with Alu elements in complex BCR-ABL translocations of chronic myeloid leukaemia
    • Jeffs A.R., Benjes S.M., Smith T.L., Sowerby S.J., and Morris C.M. The BCR gene recombines preferentially with Alu elements in complex BCR-ABL translocations of chronic myeloid leukaemia. Hum Mol Genet 7 (1998) 767-776
    • (1998) Hum Mol Genet , vol.7 , pp. 767-776
    • Jeffs, A.R.1    Benjes, S.M.2    Smith, T.L.3    Sowerby, S.J.4    Morris, C.M.5
  • 31
    • 0032478140 scopus 로고    scopus 로고
    • The partial tandem duplication of ALL1 (MLL) is consistently generated by Alu-mediated homologous recombination in acute myeloid leukaemia
    • Strout M.P., Marcucci G., Bloomfield C.D., and Caligiuri M.A. The partial tandem duplication of ALL1 (MLL) is consistently generated by Alu-mediated homologous recombination in acute myeloid leukaemia. Proc Natl Acad Sci USA 95 (1998) 2390-2395
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2390-2395
    • Strout, M.P.1    Marcucci, G.2    Bloomfield, C.D.3    Caligiuri, M.A.4
  • 32
    • 34147165221 scopus 로고    scopus 로고
    • Molecular cloning of a translocation breakpoint hotspot in 22q11
    • Kurahashi H., Inagaki H., Hosoba E., Kato T., Ohye T., Kogo H., et al. Molecular cloning of a translocation breakpoint hotspot in 22q11. Genome Res 17 (2007) 461-469
    • (2007) Genome Res , vol.17 , pp. 461-469
    • Kurahashi, H.1    Inagaki, H.2    Hosoba, E.3    Kato, T.4    Ohye, T.5    Kogo, H.6
  • 33
    • 42349085052 scopus 로고    scopus 로고
    • Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia
    • Flohr T., Schrauder A., Cazzaniga G., Panzer-Grumayer R., van der Velden V., Fischer S., et al. Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia. Leukemia 22 (2008) 771-782
    • (2008) Leukemia , vol.22 , pp. 771-782
    • Flohr, T.1    Schrauder, A.2    Cazzaniga, G.3    Panzer-Grumayer, R.4    van der Velden, V.5    Fischer, S.6
  • 35
    • 27744484826 scopus 로고    scopus 로고
    • Immunogenotype changes prevail in relapses of young children with TEL-AML1-positive acute lymphoblastic leukemia and derive mainly from clonal selection
    • Panzer-Grumayer E.R., Cazzaniga G., van der Velden V.H., del Giudice L., Peham M., Mann G., et al. Immunogenotype changes prevail in relapses of young children with TEL-AML1-positive acute lymphoblastic leukemia and derive mainly from clonal selection. Clin Cancer Res 11 (2005) 7720-7727
    • (2005) Clin Cancer Res , vol.11 , pp. 7720-7727
    • Panzer-Grumayer, E.R.1    Cazzaniga, G.2    van der Velden, V.H.3    del Giudice, L.4    Peham, M.5    Mann, G.6
  • 36
    • 33644512771 scopus 로고    scopus 로고
    • Monitoring minimal residual disease by quantification of genomic chromosomal breakpoint sequences in acute leukemias with MLL aberrations
    • Burmeister T., Marschalek R., Schneider B., Meyer C., Gokbuget N., Schwartz S., et al. Monitoring minimal residual disease by quantification of genomic chromosomal breakpoint sequences in acute leukemias with MLL aberrations. Leukemia 20 (2006) 451-457
    • (2006) Leukemia , vol.20 , pp. 451-457
    • Burmeister, T.1    Marschalek, R.2    Schneider, B.3    Meyer, C.4    Gokbuget, N.5    Schwartz, S.6
  • 37
    • 3242774615 scopus 로고    scopus 로고
    • Combined polymerase chain reaction methods to detect c-myc/IgH rearrangement in childhood Burkitt's lymphoma for minimal residual disease analysis
    • Busch K., Borkhardt A., Wossmann W., Reiter A., and Harbott J. Combined polymerase chain reaction methods to detect c-myc/IgH rearrangement in childhood Burkitt's lymphoma for minimal residual disease analysis. Haematologica 89 (2004) 818-825
    • (2004) Haematologica , vol.89 , pp. 818-825
    • Busch, K.1    Borkhardt, A.2    Wossmann, W.3    Reiter, A.4    Harbott, J.5
  • 38
    • 34347338694 scopus 로고    scopus 로고
    • TEL-AML1 preleukemic activity requires the DNA binding domain of AML1 and the dimerization and corepressor binding domains of TEL
    • Morrow M., Samanta A., Kioussis D., Brady H.J., and Williams O. TEL-AML1 preleukemic activity requires the DNA binding domain of AML1 and the dimerization and corepressor binding domains of TEL. Oncogene 26 (2007) 4404-4414
    • (2007) Oncogene , vol.26 , pp. 4404-4414
    • Morrow, M.1    Samanta, A.2    Kioussis, D.3    Brady, H.J.4    Williams, O.5
  • 39
    • 0030055379 scopus 로고    scopus 로고
    • The der(21)t(12;21) chromosome is always formed in a 12;21 translocation associated with childhood acute lymphoblastic leukaemia
    • Kobayashi H., Satake N., Maseki N., Sakashita A., and Kaneko Y. The der(21)t(12;21) chromosome is always formed in a 12;21 translocation associated with childhood acute lymphoblastic leukaemia. Br J Haematol 94 (1996) 105-111
    • (1996) Br J Haematol , vol.94 , pp. 105-111
    • Kobayashi, H.1    Satake, N.2    Maseki, N.3    Sakashita, A.4    Kaneko, Y.5
  • 40
    • 0035942491 scopus 로고    scopus 로고
    • Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL
    • Reichel M., Gillert E., Angermuller S., Hensel J.P., Heidel F., Lode M., et al. Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL. Oncogene 20 (2001) 2900-2907
    • (2001) Oncogene , vol.20 , pp. 2900-2907
    • Reichel, M.1    Gillert, E.2    Angermuller, S.3    Hensel, J.P.4    Heidel, F.5    Lode, M.6
  • 42
    • 0035195004 scopus 로고    scopus 로고
    • Molecular characterization of genomic AML1-ETO fusions in childhood leukemia
    • Xiao Z., Greaves M.F., Buffler P., Smith M.T., Segal M.R., Dicks B.M., et al. Molecular characterization of genomic AML1-ETO fusions in childhood leukemia. Leukemia 15 (2001) 1906-1913
    • (2001) Leukemia , vol.15 , pp. 1906-1913
    • Xiao, Z.1    Greaves, M.F.2    Buffler, P.3    Smith, M.T.4    Segal, M.R.5    Dicks, B.M.6
  • 43
    • 0035254207 scopus 로고    scopus 로고
    • Breakage and fusion of the TEL (ETV6) gene in immature B lymphocytes induced by apoptogenic signals
    • Eguchi-Ishimae M., Eguchi M., Ishii E., Miyazaki S., Ueda K., Kamada N., et al. Breakage and fusion of the TEL (ETV6) gene in immature B lymphocytes induced by apoptogenic signals. Blood 97 (2001) 737-743
    • (2001) Blood , vol.97 , pp. 737-743
    • Eguchi-Ishimae, M.1    Eguchi, M.2    Ishii, E.3    Miyazaki, S.4    Ueda, K.5    Kamada, N.6


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