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Volumn 220, Issue 1, 2011, Pages 9-19

Serotonergic involvement in methamphetamine-induced locomotor activity: A detailed pharmacological study

Author keywords

5 HT1B; 5 HT2A; 5 HT2C; D1; D2; Dopamine receptors; Methamphetamine; Serotonin receptors

Indexed keywords

1,2,3,4,8,9,10,10A OCTAHYDRO 7BH CYCLOPENTA[B][1,4]DIAZEPINO[6,7,1 HI]INDOLE; 2 (6 CHLORO 5 FLUORO 1 INDOLYL) 1 METHYLETHYLAMINE; 6 CHLORO 5 METHYL 1 [[2 [(2 METHYL 3 PYRIDYL)OXY] 5 PYRIDYL]CARBAMOYL]INDOLINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; ARIPIPRAZOLE; CLOZAPINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; FENCLONINE; FLUVOXAMINE; HALOPERIDOL; METHAMPHETAMINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; TERGURIDE; VOLINANSERIN;

EID: 79751530808     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2011.01.026     Document Type: Article
Times cited : (36)

References (85)
  • 2
    • 29344436259 scopus 로고    scopus 로고
    • Repeated methamphetamine treatment impairs recognition memory through a failure of novelty-induced ERK1/2 activation in the prefrontal cortex of mice
    • Kamei H, Nagai T., Nakano H., Togan Y., Takayanagi M., Takahashi K., et al. Repeated methamphetamine treatment impairs recognition memory through a failure of novelty-induced ERK1/2 activation in the prefrontal cortex of mice. Biol Psychiatry 2006, 59:75-84.
    • (2006) Biol Psychiatry , vol.59 , pp. 75-84
    • Kamei, H.1    Nagai, T.2    Nakano, H.3    Togan, Y.4    Takayanagi, M.5    Takahashi, K.6
  • 3
    • 0035095014 scopus 로고    scopus 로고
    • Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers
    • Volkow N.D., Chang L., Wang G.J., Fowler J.S., Franceschi D., Sedler M.J., et al. Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers. Am J Psychiatry 2001, 158:377-382.
    • (2001) Am J Psychiatry , vol.158 , pp. 377-382
    • Volkow, N.D.1    Chang, L.2    Wang, G.J.3    Fowler, J.S.4    Franceschi, D.5    Sedler, M.J.6
  • 4
    • 0032567775 scopus 로고    scopus 로고
    • Methamphetamine-induced alterations in dopamine transporter function
    • Bennett B.A., Hollingsworth C.K., Martin S., Harp J.J. Methamphetamine-induced alterations in dopamine transporter function. Brain Res 1997, 782:219-227.
    • (1997) Brain Res , vol.782 , pp. 219-227
    • Bennett, B.A.1    Hollingsworth, C.K.2    Martin, S.3    Harp, J.J.4
  • 5
    • 0032514174 scopus 로고    scopus 로고
    • Methamphetamine treatment rapidly inhibits serotonin, but not glutamate, transporters in the rat brain
    • Kokoshka J.M., Metzger R.R., Wilkins D.G., Gibb J.W., Hanson G.R., Fleckenstein A.E. Methamphetamine treatment rapidly inhibits serotonin, but not glutamate, transporters in the rat brain. Brain Res 1998, 799:78-83.
    • (1998) Brain Res , vol.799 , pp. 78-83
    • Kokoshka, J.M.1    Metzger, R.R.2    Wilkins, D.G.3    Gibb, J.W.4    Hanson, G.R.5    Fleckenstein, A.E.6
  • 6
    • 0032748330 scopus 로고    scopus 로고
    • Differential effects of psychostimulants and related agents on dopaminergic and serotonergic transporter function
    • Fleckenstein A.E., Haughey H.M., Metzger R.R., Kokoshka J.M., Riddle E.L., Hanson J.E., et al. Differential effects of psychostimulants and related agents on dopaminergic and serotonergic transporter function. Eur J Pharmacol 1999, 382:45-49.
    • (1999) Eur J Pharmacol , vol.382 , pp. 45-49
    • Fleckenstein, A.E.1    Haughey, H.M.2    Metzger, R.R.3    Kokoshka, J.M.4    Riddle, E.L.5    Hanson, J.E.6
  • 7
    • 0034613214 scopus 로고    scopus 로고
    • Differential effects of stimulants on monoaminergic transporters: pharmacological consequences and implications for neurotoxicity
    • Fleckenstein A.E., Gibb J.W., Hanson G.R. Differential effects of stimulants on monoaminergic transporters: pharmacological consequences and implications for neurotoxicity. Eur J Pharmacol 2000, 406:1-13.
    • (2000) Eur J Pharmacol , vol.406 , pp. 1-13
    • Fleckenstein, A.E.1    Gibb, J.W.2    Hanson, G.R.3
  • 8
    • 38149089449 scopus 로고    scopus 로고
    • 5-HT1B receptor-mediated serotonergic modulation of methylphenidate locomotor activation in rats
    • Borycz J., Zapata A., Quiroz C., Volkow N.D., Ferre S. 5-HT1B receptor-mediated serotonergic modulation of methylphenidate locomotor activation in rats. Neuropsychopharmacology 2008, 33:619-626.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 619-626
    • Borycz, J.1    Zapata, A.2    Quiroz, C.3    Volkow, N.D.4    Ferre, S.5
  • 9
    • 0028944943 scopus 로고
    • Hippocampus norepinephrine, caudate dopamine and serotoning, and behavioural response to the stereoisomers of amphetamine and methamphetamine
    • Kuczenski R., Segal D.S., Cho A.K., Melega W. Hippocampus norepinephrine, caudate dopamine and serotoning, and behavioural response to the stereoisomers of amphetamine and methamphetamine. J Neurosci 1995, 15:1308-1317.
    • (1995) J Neurosci , vol.15 , pp. 1308-1317
    • Kuczenski, R.1    Segal, D.S.2    Cho, A.K.3    Melega, W.4
  • 10
    • 0022557235 scopus 로고
    • Roles of D1 and D2 dopamine receptor sub types in mediating the methamphetamine-induced changes in monoamine systems
    • Sonsalla P.K., Gibb J.W., Hanson G.R. Roles of D1 and D2 dopamine receptor sub types in mediating the methamphetamine-induced changes in monoamine systems. J Pharmacol Exp Ther 1986, 238:932-937.
    • (1986) J Pharmacol Exp Ther , vol.238 , pp. 932-937
    • Sonsalla, P.K.1    Gibb, J.W.2    Hanson, G.R.3
  • 11
    • 0027440524 scopus 로고
    • Effects of the dopamine release inhibitor, CGS 10746B, on the locomotor stimulant and discriminative stimulus effects of cocaine and methamphetamine
    • French D., Witkin J.M. Effects of the dopamine release inhibitor, CGS 10746B, on the locomotor stimulant and discriminative stimulus effects of cocaine and methamphetamine. Pharmacol Biochem Behav 1993, 46:989-993.
    • (1993) Pharmacol Biochem Behav , vol.46 , pp. 989-993
    • French, D.1    Witkin, J.M.2
  • 12
    • 0032982424 scopus 로고    scopus 로고
    • Behavioural, toxic, and neurochemical effects of sydnocarb, a novel psychomotor stimulant: comparisons with methamphetamine
    • Witkin J.M., Savtchenko N., Mashkovsky M., Beekman M., Munzar P., Gasior M., et al. Behavioural, toxic, and neurochemical effects of sydnocarb, a novel psychomotor stimulant: comparisons with methamphetamine. J Pharmacol Exp Ther 1999, 288:1298-1310.
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 1298-1310
    • Witkin, J.M.1    Savtchenko, N.2    Mashkovsky, M.3    Beekman, M.4    Munzar, P.5    Gasior, M.6
  • 13
    • 47249102922 scopus 로고    scopus 로고
    • Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice
    • Kelly M.A., Low M.J., Rubinstein M., Phillips T.J. Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice. Genes Brain Behav 2008, 7:568-577.
    • (2008) Genes Brain Behav , vol.7 , pp. 568-577
    • Kelly, M.A.1    Low, M.J.2    Rubinstein, M.3    Phillips, T.J.4
  • 14
    • 33646905401 scopus 로고    scopus 로고
    • Reversal of methamphetamine-induced behavioural sensitization by repeated administration of a dopamine D1 receptor agonist
    • Shuto T., Kuroiwa M., Hamamura M., Yabuuchi K., Shimazoe T., Watanabe S., et al. Reversal of methamphetamine-induced behavioural sensitization by repeated administration of a dopamine D1 receptor agonist. Neuropharmacology 2006, 50:991-997.
    • (2006) Neuropharmacology , vol.50 , pp. 991-997
    • Shuto, T.1    Kuroiwa, M.2    Hamamura, M.3    Yabuuchi, K.4    Shimazoe, T.5    Watanabe, S.6
  • 15
    • 73949156045 scopus 로고    scopus 로고
    • Blockade of D1 dopamine receptors in the medial prefrontal cortex attenuates amphetamine- and methamphetamine-induced locomotor activity in the rat
    • Hall D.A., Powers J.P., Gulley J.M. Blockade of D1 dopamine receptors in the medial prefrontal cortex attenuates amphetamine- and methamphetamine-induced locomotor activity in the rat. Brain Res 2009, 1300:51-57.
    • (2009) Brain Res , vol.1300 , pp. 51-57
    • Hall, D.A.1    Powers, J.P.2    Gulley, J.M.3
  • 16
    • 8244242524 scopus 로고    scopus 로고
    • The atypical antipsychotic profile of NRA0045, a novel dopamine D4 and 5-hydroxytryptamine2A receptor antagonist, in rats
    • Okuyama S., Chaki S., Kawashima N., Suzuki Y., Ogawa S., Kumagai T., et al. The atypical antipsychotic profile of NRA0045, a novel dopamine D4 and 5-hydroxytryptamine2A receptor antagonist, in rats. Br J Pharmacol 1997, 121:515-525.
    • (1997) Br J Pharmacol , vol.121 , pp. 515-525
    • Okuyama, S.1    Chaki, S.2    Kawashima, N.3    Suzuki, Y.4    Ogawa, S.5    Kumagai, T.6
  • 17
    • 77955282388 scopus 로고    scopus 로고
    • Pharmacological, neurochemical, and behavioural profile of JB-788, a new 5-HT1A agonist
    • Picard M., Morisset S., Cloix J.F., Bizot J.C., Guerin M., Beneteau V., et al. Pharmacological, neurochemical, and behavioural profile of JB-788, a new 5-HT1A agonist. Neuroscience 2010, 169:1337-1346.
    • (2010) Neuroscience , vol.169 , pp. 1337-1346
    • Picard, M.1    Morisset, S.2    Cloix, J.F.3    Bizot, J.C.4    Guerin, M.5    Beneteau, V.6
  • 18
    • 0025291021 scopus 로고
    • Pharmacological actions of SM-9018, a new neuroleptic drug with both potent 5-hydroxytryptamine2 and dopamine2 antagonistic actions
    • Hirose A., Kato T., Ohno Y., Shimizu H., Tanaka H., Nakamura M., et al. Pharmacological actions of SM-9018, a new neuroleptic drug with both potent 5-hydroxytryptamine2 and dopamine2 antagonistic actions. Jpn J Pharmacol 1990, 53:321-329.
    • (1990) Jpn J Pharmacol , vol.53 , pp. 321-329
    • Hirose, A.1    Kato, T.2    Ohno, Y.3    Shimizu, H.4    Tanaka, H.5    Nakamura, M.6
  • 19
    • 2542577736 scopus 로고    scopus 로고
    • Effects of dopamine D1- or D2-like receptor antagonists on the hypermotive and discriminative stimulus effects of (+)-MDMA
    • Bubar M.J., Pack K.M., Frankel P.S., Cunningham K.A. Effects of dopamine D1- or D2-like receptor antagonists on the hypermotive and discriminative stimulus effects of (+)-MDMA. Psychopharmacology 2004, 173:326-336.
    • (2004) Psychopharmacology , vol.173 , pp. 326-336
    • Bubar, M.J.1    Pack, K.M.2    Frankel, P.S.3    Cunningham, K.A.4
  • 20
    • 0026546876 scopus 로고
    • The molecular mechanism of "ecstasy" [3,4-methylenedioxy-methamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release
    • Rudnick G., Wall S.C. The molecular mechanism of "ecstasy" [3,4-methylenedioxy-methamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release. Proc Natl Acad Sci USA 1992, 89:1817-1821.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1817-1821
    • Rudnick, G.1    Wall, S.C.2
  • 21
    • 0025874931 scopus 로고
    • Amphetamine derivatives induce locomotor hyperactivity by acting as indirect serotonin agonists
    • Callaway C.W., Johnson M.P., Gold L.H., Nichols D.E., Geyer M.A. Amphetamine derivatives induce locomotor hyperactivity by acting as indirect serotonin agonists. Psychopharmacology 1991, 104:293-301.
    • (1991) Psychopharmacology , vol.104 , pp. 293-301
    • Callaway, C.W.1    Johnson, M.P.2    Gold, L.H.3    Nichols, D.E.4    Geyer, M.A.5
  • 22
    • 0032808480 scopus 로고    scopus 로고
    • Pharmacological studies of the acute and chronic effects of (+)-3,4-methylenedioxymethamphetamine on locomotor activity: role of 5-hydroxytryptamine1a and 5-hydroxytryptamine1b/1D receptors
    • McCreary A.C., Bankson M.G., Cunningham K.A. Pharmacological studies of the acute and chronic effects of (+)-3,4-methylenedioxymethamphetamine on locomotor activity: role of 5-hydroxytryptamine1a and 5-hydroxytryptamine1b/1D receptors. J Pharmacol Exp Ther 1999, 290:965-973.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 965-973
    • McCreary, A.C.1    Bankson, M.G.2    Cunningham, K.A.3
  • 24
    • 0035667338 scopus 로고    scopus 로고
    • Differential effects of dopamine antagonists on locomotor activity, conditioned activity and conditioned place preference induced by cocaine in rats
    • Adams J.U., Careri J.M., Efferen T.R., Rotrosen J. Differential effects of dopamine antagonists on locomotor activity, conditioned activity and conditioned place preference induced by cocaine in rats. Behav Pharmacol 2001, 12:603-611.
    • (2001) Behav Pharmacol , vol.12 , pp. 603-611
    • Adams, J.U.1    Careri, J.M.2    Efferen, T.R.3    Rotrosen, J.4
  • 25
    • 5444225824 scopus 로고    scopus 로고
    • Role of serotonin2A receptors in the D-amphetamine-induced release of dopamine: comparison with previous data on alpha1b-adrenergic receptors
    • Auclair A., Blanc G., Glowinski J., Tassin J.P. Role of serotonin2A receptors in the D-amphetamine-induced release of dopamine: comparison with previous data on alpha1b-adrenergic receptors. J Neurochem 2004, 91:318-326.
    • (2004) J Neurochem , vol.91 , pp. 318-326
    • Auclair, A.1    Blanc, G.2    Glowinski, J.3    Tassin, J.P.4
  • 26
    • 0035012074 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine (MDMA) as a unique model or serotonin receptor function and serotonin-dopamine interactions
    • Bankson M.G., Cunningham K.A. 3,4-Methylenedioxymethamphetamine (MDMA) as a unique model or serotonin receptor function and serotonin-dopamine interactions. J Pharmacol Exp Ther 2001, 297:846-852.
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 846-852
    • Bankson, M.G.1    Cunningham, K.A.2
  • 27
    • 4243187058 scopus 로고    scopus 로고
    • Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses
    • Filip M., Bubar M.J., Cunningham K.A. Contribution of serotonin (5-hydroxytryptamine; 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine: acute and chronic pharmacological analyses. J Pharmacol Exp Ther 2004, 310:1246-1254.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 1246-1254
    • Filip, M.1    Bubar, M.J.2    Cunningham, K.A.3
  • 29
    • 0033009962 scopus 로고    scopus 로고
    • Effects of D1 and D2 dopamine receptor antagonists on cocaine-induced self-stimulation and locomotor activity in rats
    • Kita K., Shiratani T., Takenouchi K., Fukuzako H., Takigawa M. Effects of D1 and D2 dopamine receptor antagonists on cocaine-induced self-stimulation and locomotor activity in rats. Eur Neuropsychopharmacol 1999, 9:1-7.
    • (1999) Eur Neuropsychopharmacol , vol.9 , pp. 1-7
    • Kita, K.1    Shiratani, T.2    Takenouchi, K.3    Fukuzako, H.4    Takigawa, M.5
  • 30
    • 0027419352 scopus 로고
    • Cocaine-induced behaviour: dopamine D1 receptor antagonism by SCH 23390 prevents expression of conditioned sensitisation following repeated administration of cocaine
    • McCreary A.C., Marsden C.A. Cocaine-induced behaviour: dopamine D1 receptor antagonism by SCH 23390 prevents expression of conditioned sensitisation following repeated administration of cocaine. Neuropharmacology 1993, 32:387-391.
    • (1993) Neuropharmacology , vol.32 , pp. 387-391
    • McCreary, A.C.1    Marsden, C.A.2
  • 31
    • 0035084161 scopus 로고    scopus 로고
    • Antagonism of 5-hydroxytryptamine2a receptors attenuates the behavioural effects of cocaine in rats
    • McMahon L.R., Cunningham K.A. Antagonism of 5-hydroxytryptamine2a receptors attenuates the behavioural effects of cocaine in rats. J Pharmacol Exp Ther 2001, 297:357-363.
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 357-363
    • McMahon, L.R.1    Cunningham, K.A.2
  • 32
    • 0030070276 scopus 로고    scopus 로고
    • Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY100635, a potent, selective and silent 5-HT1A receptor antagonist
    • Fletcher P.J., Forster E.A., Bill D.J., Brown G., Cliffe I.A., Hartley J.E., et al. Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY100635, a potent, selective and silent 5-HT1A receptor antagonist. Behav Brain Res 1996, 73:337-353.
    • (1996) Behav Brain Res , vol.73 , pp. 337-353
    • Fletcher, P.J.1    Forster, E.A.2    Bill, D.J.3    Brown, G.4    Cliffe, I.A.5    Hartley, J.E.6
  • 34
    • 20344392672 scopus 로고    scopus 로고
    • Differential effects of 5-HT2C receptor ligands on place conditioning and locomotor activity in rats
    • Mosher T., Hayes D., Greenshaw A. Differential effects of 5-HT2C receptor ligands on place conditioning and locomotor activity in rats. Eur J Pharmacol 2005, 515:107-116.
    • (2005) Eur J Pharmacol , vol.515 , pp. 107-116
    • Mosher, T.1    Hayes, D.2    Greenshaw, A.3
  • 35
    • 0036791976 scopus 로고    scopus 로고
    • Differential effects of the 5HT2A receptor antagonist M100,907 and the 5HT2C receptor antagonist SB242,084 on cocaine-induced locomotor activity, cocaine self-administration and cocaine-induced reinstatement of responding
    • Fletcher P.J., Grottick A.J., Higgin G.A. Differential effects of the 5HT2A receptor antagonist M100,907 and the 5HT2C receptor antagonist SB242,084 on cocaine-induced locomotor activity, cocaine self-administration and cocaine-induced reinstatement of responding. Neuropsychopharmacology 2002, 27:576-586.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 576-586
    • Fletcher, P.J.1    Grottick, A.J.2    Higgin, G.A.3
  • 36
    • 20944441963 scopus 로고    scopus 로고
    • WAY-163909 ((7bR,10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole): a novel 5-HT2C receptor selective agonist with anorectic activity
    • Dunlop J., Sabb A.L., Mazandarani H., Zhang J., Kalgaonker S., Shukhina E., et al. WAY-163909 ((7bR,10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole): a novel 5-HT2C receptor selective agonist with anorectic activity. J Pharmacol Exp Ther 2005, 313:862-869.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 862-869
    • Dunlop, J.1    Sabb, A.L.2    Mazandarani, H.3    Zhang, J.4    Kalgaonker, S.5    Shukhina, E.6
  • 37
    • 0033680203 scopus 로고    scopus 로고
    • Studies to investigate the role of 5-HT(2C) receptors on cocaine- and food-maintained behaviour
    • Grottick A.J., Fletcher P.J., Higgins G.A. Studies to investigate the role of 5-HT(2C) receptors on cocaine- and food-maintained behaviour. J Pharmacol Exp Ther 2000, 295:1183-1191.
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 1183-1191
    • Grottick, A.J.1    Fletcher, P.J.2    Higgins, G.A.3
  • 38
    • 23844470651 scopus 로고    scopus 로고
    • Aripiprazole increases dopamine but not noradrenaline and serotonin levels in the mouse prefrontal cortex
    • Zocchi A., Fabbri D., Heidbreder C.A. Aripiprazole increases dopamine but not noradrenaline and serotonin levels in the mouse prefrontal cortex. Neurosci Lett 2005, 387:157-161.
    • (2005) Neurosci Lett , vol.387 , pp. 157-161
    • Zocchi, A.1    Fabbri, D.2    Heidbreder, C.A.3
  • 39
    • 0034117854 scopus 로고    scopus 로고
    • PD 158771, a potential antipsychotic agent with D2/D3 partial agonist and 5-HT1A agonist actions. II Preclinical behavioural effects
    • Corbin A.E., Meltzer L.T., Ninteman F.W., Wiley J.N., Christoffersen C.L., Wustros D.J., et al. PD 158771, a potential antipsychotic agent with D2/D3 partial agonist and 5-HT1A agonist actions. II Preclinical behavioural effects. Neuropharmacology 2000, 39:1211-1221.
    • (2000) Neuropharmacology , vol.39 , pp. 1211-1221
    • Corbin, A.E.1    Meltzer, L.T.2    Ninteman, F.W.3    Wiley, J.N.4    Christoffersen, C.L.5    Wustros, D.J.6
  • 41
    • 0018192659 scopus 로고
    • Drug interactions with brain biogenic amines and the effects of amphetamine isomers on locomotor activity
    • Zabik J.E., Levine R.M. Drug interactions with brain biogenic amines and the effects of amphetamine isomers on locomotor activity. Pharmacol Biochem Behav 1978, 8:429-435.
    • (1978) Pharmacol Biochem Behav , vol.8 , pp. 429-435
    • Zabik, J.E.1    Levine, R.M.2
  • 42
    • 0017096948 scopus 로고
    • Differential effects of para-chlorophenylalanine on amphetamine-induced locomotion and stereotypy
    • Segal D.S. Differential effects of para-chlorophenylalanine on amphetamine-induced locomotion and stereotypy. Brain Res 1976, 116:267-276.
    • (1976) Brain Res , vol.116 , pp. 267-276
    • Segal, D.S.1
  • 43
    • 0033041433 scopus 로고    scopus 로고
    • Modulatory effects of p-chlorophenylalanine microinjected into the dorsal and median raphe nuclei on cocaine-induced behaviour in the rat
    • Herges S., Taylor D.A. Modulatory effects of p-chlorophenylalanine microinjected into the dorsal and median raphe nuclei on cocaine-induced behaviour in the rat. Eur J Pharmacol 1999, 374:329-340.
    • (1999) Eur J Pharmacol , vol.374 , pp. 329-340
    • Herges, S.1    Taylor, D.A.2
  • 44
    • 0001823451 scopus 로고
    • Cocaine: discussion on the role of dopamine in the biochemical mechanism of action
    • Plenum, New York, E.H. Ellinwood, M.M. Kilbey (Eds.)
    • Scheel-Kruger J., Braestrup C., Nielson M., Golembiowska K., Mogilnicka E. Cocaine: discussion on the role of dopamine in the biochemical mechanism of action. Cocaine and other stimulants 1977, 373-407. Plenum, New York. E.H. Ellinwood, M.M. Kilbey (Eds.).
    • (1977) Cocaine and other stimulants , pp. 373-407
    • Scheel-Kruger, J.1    Braestrup, C.2    Nielson, M.3    Golembiowska, K.4    Mogilnicka, E.5
  • 45
    • 0026571940 scopus 로고
    • Stimulant effects of 3,4-methylenedioxymethamphetamine in the nucleus accumbens of rat
    • Callaway C.W., Geyer M.A. Stimulant effects of 3,4-methylenedioxymethamphetamine in the nucleus accumbens of rat. Eur J Pharmacol 1992, 214:45-51.
    • (1992) Eur J Pharmacol , vol.214 , pp. 45-51
    • Callaway, C.W.1    Geyer, M.A.2
  • 46
    • 0025108906 scopus 로고
    • Serotonin release contributes to the locomotor stimulant effects of 3,4-methylenedioxymethamphetamine in rats
    • Callaway C.W., Wing L.L., Geyer M.A. Serotonin release contributes to the locomotor stimulant effects of 3,4-methylenedioxymethamphetamine in rats. J Pharmacol Exp Ther 1990, 254:456-464.
    • (1990) J Pharmacol Exp Ther , vol.254 , pp. 456-464
    • Callaway, C.W.1    Wing, L.L.2    Geyer, M.A.3
  • 47
    • 26944489620 scopus 로고    scopus 로고
    • Serotonin-transporter mediated efflux: a pharmacological analysis of amphetamines and non-amphetamines
    • Hilber B., Scholze P., Dorostka M.M., Sandtner W., Holy M., Boehm S., et al. Serotonin-transporter mediated efflux: a pharmacological analysis of amphetamines and non-amphetamines. Neuropharmacology 2005, 49:811-819.
    • (2005) Neuropharmacology , vol.49 , pp. 811-819
    • Hilber, B.1    Scholze, P.2    Dorostka, M.M.3    Sandtner, W.4    Holy, M.5    Boehm, S.6
  • 48
    • 0027946258 scopus 로고
    • In vivo biogenic amine efflux in medial prefrontal cortex with imipramine, fluoxetine and fluvoxamine
    • Jordan S., Kramer G.L., Zukas P.K., Moeller M., Petty F. In vivo biogenic amine efflux in medial prefrontal cortex with imipramine, fluoxetine and fluvoxamine. Synapse 1994, 18:294-297.
    • (1994) Synapse , vol.18 , pp. 294-297
    • Jordan, S.1    Kramer, G.L.2    Zukas, P.K.3    Moeller, M.4    Petty, F.5
  • 49
    • 0037371559 scopus 로고    scopus 로고
    • Selective serotonin uptake inhibitors enhance cocaine-induced locomotor activity and dopamine release in the nucleus accumbens
    • Bubar M.J., McMahon L.R., De Deurwaerdere P., Spampinato U., Cunningham K.A. Selective serotonin uptake inhibitors enhance cocaine-induced locomotor activity and dopamine release in the nucleus accumbens. Neuropharmacology 2003, 44:342-353.
    • (2003) Neuropharmacology , vol.44 , pp. 342-353
    • Bubar, M.J.1    McMahon, L.R.2    De Deurwaerdere, P.3    Spampinato, U.4    Cunningham, K.A.5
  • 50
    • 0032925893 scopus 로고    scopus 로고
    • Acute fluoxetine treatment potentiates amphetamine hyperactivity and amphetamine-induced nucleus accumbens dopamine release: possible pharmacokinetic interaction
    • Sills T.L., Greenshaw A.J., Baker G.B., Fletcher P.J. Acute fluoxetine treatment potentiates amphetamine hyperactivity and amphetamine-induced nucleus accumbens dopamine release: possible pharmacokinetic interaction. Psychopharmacology (Berl) 1999, 141:421-427.
    • (1999) Psychopharmacology (Berl) , vol.141 , pp. 421-427
    • Sills, T.L.1    Greenshaw, A.J.2    Baker, G.B.3    Fletcher, P.J.4
  • 51
    • 23944504501 scopus 로고    scopus 로고
    • Involvement of sigma (sigma) receptors in the acute actions of methamphetamine: receptor binding and behavioural studies
    • Nguyen E.C., McCracken K.A., Liu Y., Pouw B., Matsumoto R.R. Involvement of sigma (sigma) receptors in the acute actions of methamphetamine: receptor binding and behavioural studies. Neuropharmacology 2005, 49:638-645.
    • (2005) Neuropharmacology , vol.49 , pp. 638-645
    • Nguyen, E.C.1    McCracken, K.A.2    Liu, Y.3    Pouw, B.4    Matsumoto, R.R.5
  • 52
    • 0036007937 scopus 로고    scopus 로고
    • 5-HT3 receptor antagonist MDL72222 attenuates cocaine- and mazindol-, but not methylphenidate-induced neurochemical and behavioural effects in the rat
    • Kankaanpää A., Meririnne E., Seppälä T. 5-HT3 receptor antagonist MDL72222 attenuates cocaine- and mazindol-, but not methylphenidate-induced neurochemical and behavioural effects in the rat. Psychopharmacology (Berl) 2002, 159:341-350.
    • (2002) Psychopharmacology (Berl) , vol.159 , pp. 341-350
    • Kankaanpää, A.1    Meririnne, E.2    Seppälä, T.3
  • 53
    • 0024779523 scopus 로고
    • Pharmacologic profile of amphetamine derivatives at various brain recognition sites: selective effects on serotonergic systems
    • Battaglia G., De Souza E.B. Pharmacologic profile of amphetamine derivatives at various brain recognition sites: selective effects on serotonergic systems. NIDA Res Monogr 1989, 94:240-258.
    • (1989) NIDA Res Monogr , vol.94 , pp. 240-258
    • Battaglia, G.1    De Souza, E.B.2
  • 54
    • 4043091277 scopus 로고    scopus 로고
    • Dopaminergic and serotonergic autoreceptor stimulation effects are equivalent and additive in the suppression of spontaneous and cocaine induced locomotor activity
    • Carey R.J., De Palma G., Damianopoulos E., Hopkins A., Shanahan A., Muller C.P., et al. Dopaminergic and serotonergic autoreceptor stimulation effects are equivalent and additive in the suppression of spontaneous and cocaine induced locomotor activity. Brain Res 2004, 1019:134-143.
    • (2004) Brain Res , vol.1019 , pp. 134-143
    • Carey, R.J.1    De Palma, G.2    Damianopoulos, E.3    Hopkins, A.4    Shanahan, A.5    Muller, C.P.6
  • 55
    • 0035969331 scopus 로고    scopus 로고
    • Cocaine and serotonin: a role for the 5-HT(1A) receptor site in the mediation of cocaine stimulant effects
    • Carey R.J., De Palma G., Damianopoulos E. Cocaine and serotonin: a role for the 5-HT(1A) receptor site in the mediation of cocaine stimulant effects. Behav Brain Res 2001, 126:127-133.
    • (2001) Behav Brain Res , vol.126 , pp. 127-133
    • Carey, R.J.1    De Palma, G.2    Damianopoulos, E.3
  • 56
    • 31844438317 scopus 로고    scopus 로고
    • Determining the region-specific contributions of 5-HT receptors to the psychostimulant effects of cocaine
    • Müller C.P., Huston J.P. Determining the region-specific contributions of 5-HT receptors to the psychostimulant effects of cocaine. Trends Pharmacol Sci 2006, 27:105-112.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 105-112
    • Müller, C.P.1    Huston, J.P.2
  • 57
    • 0031445970 scopus 로고    scopus 로고
    • Stimulation of 5-HT1A receptors attenuates the locomotor, but not the discriminative, effects of amphetamine and cocaine in rats
    • Przegalinski E., Filip M. Stimulation of 5-HT1A receptors attenuates the locomotor, but not the discriminative, effects of amphetamine and cocaine in rats. Behav Pharmacol 1997, 8:699-706.
    • (1997) Behav Pharmacol , vol.8 , pp. 699-706
    • Przegalinski, E.1    Filip, M.2
  • 58
    • 0033956968 scopus 로고    scopus 로고
    • The effects of 5-hydroxytryptamine(1A) agonist 8-hydroxy-2-(di-n-propulamino)tetralin on spontaneous activity, cocaine-induced behavioural sensitization: a microanalysis of locomotor activity
    • De la Garza R., Cunningham K.A. The effects of 5-hydroxytryptamine(1A) agonist 8-hydroxy-2-(di-n-propulamino)tetralin on spontaneous activity, cocaine-induced behavioural sensitization: a microanalysis of locomotor activity. J Pharmacol Exp Ther 2000, 292:610-617.
    • (2000) J Pharmacol Exp Ther , vol.292 , pp. 610-617
    • De la Garza, R.1    Cunningham, K.A.2
  • 59
    • 0030431577 scopus 로고    scopus 로고
    • Preclinical characterization of the potential of the putative atypical antipsychotic MDL100,907 as a potent 5-HT2A antagonist with a favourable CNS safety profile
    • Kehne J.H., Baron B.M., Carr A.A., Chaney S.F., Elands J., Feldman D.J., et al. Preclinical characterization of the potential of the putative atypical antipsychotic MDL100,907 as a potent 5-HT2A antagonist with a favourable CNS safety profile. J Pharmacol Exp Ther 1996, 277:968-981.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 968-981
    • Kehne, J.H.1    Baron, B.M.2    Carr, A.A.3    Chaney, S.F.4    Elands, J.5    Feldman, D.J.6
  • 60
    • 0035478667 scopus 로고    scopus 로고
    • Differential regulation of the mesoaccumbens circuit by serotonin 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors
    • McMahon L.R., Filip M., Cunningham K.A. Differential regulation of the mesoaccumbens circuit by serotonin 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors. J Neurosci 2001, 21:7781-7787.
    • (2001) J Neurosci , vol.21 , pp. 7781-7787
    • McMahon, L.R.1    Filip, M.2    Cunningham, K.A.3
  • 61
    • 0842308153 scopus 로고    scopus 로고
    • Injection of the 5-HT2C receptor agonist Ro60-0175 into the ventral tegmental area reduces cocaine-induced locomotor activity and cocaine self-administration
    • Fletcher P.J., Chintoh A.F., Sinyard J., Higgins G.A. Injection of the 5-HT2C receptor agonist Ro60-0175 into the ventral tegmental area reduces cocaine-induced locomotor activity and cocaine self-administration. Nueropsychopharmacology 2004, 29:308-318.
    • (2004) Nueropsychopharmacology , vol.29 , pp. 308-318
    • Fletcher, P.J.1    Chintoh, A.F.2    Sinyard, J.3    Higgins, G.A.4
  • 62
    • 0032188850 scopus 로고    scopus 로고
    • Electrophysiological characterization of GABAergic neurons in the ventral tegmental area
    • Steffenson S.C., Svingos A.L., Pickel V.M., Henrikson S.J. Electrophysiological characterization of GABAergic neurons in the ventral tegmental area. J Neurosci 1998, 18:8003-8015.
    • (1998) J Neurosci , vol.18 , pp. 8003-8015
    • Steffenson, S.C.1    Svingos, A.L.2    Pickel, V.M.3    Henrikson, S.J.4
  • 63
    • 38149121526 scopus 로고    scopus 로고
    • Selective ablation of GABA neurons in the ventral tegmental area increases spontaneous locomotor activity
    • Shank E.J., Seitz P.K., Bubar M.J., Stutz S.J., Cunningham K.A. Selective ablation of GABA neurons in the ventral tegmental area increases spontaneous locomotor activity. Behav Neurosci 2007, 121:1224-1233.
    • (2007) Behav Neurosci , vol.121 , pp. 1224-1233
    • Shank, E.J.1    Seitz, P.K.2    Bubar, M.J.3    Stutz, S.J.4    Cunningham, K.A.5
  • 64
    • 34247469816 scopus 로고    scopus 로고
    • Distribution of serotonin 5-HT2C receptors in the ventral tegmental area
    • Bubar M.J., Cunningham K.A. Distribution of serotonin 5-HT2C receptors in the ventral tegmental area. Neuroscience 2007, 146:286-297.
    • (2007) Neuroscience , vol.146 , pp. 286-297
    • Bubar, M.J.1    Cunningham, K.A.2
  • 65
    • 0029037007 scopus 로고
    • Modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and gamma-aminobutyric acid in the substantia nigra
    • Yamamoto B.K., Nash J.F., Gudelsky G.A. Modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and gamma-aminobutyric acid in the substantia nigra. J Pharmacol Exp Ther 1995, 273:1063-1070.
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 1063-1070
    • Yamamoto, B.K.1    Nash, J.F.2    Gudelsky, G.A.3
  • 66
    • 0030070015 scopus 로고    scopus 로고
    • Carrier-mediated release of serotonin by 3, 4-methylenedioxymethamphetamine: implications for serotonin-dopamine interactions
    • Gudelsky G.A., Nash J.F. Carrier-mediated release of serotonin by 3, 4-methylenedioxymethamphetamine: implications for serotonin-dopamine interactions. J Neurochem 1996, 66:243-249.
    • (1996) J Neurochem , vol.66 , pp. 243-249
    • Gudelsky, G.A.1    Nash, J.F.2
  • 67
    • 0034640439 scopus 로고    scopus 로고
    • Ultrasonic localization of the serotonin 2A receptor in dopaminergic neurons in the ventral tegmental area
    • Doherty M.D., Pickel V.M. Ultrasonic localization of the serotonin 2A receptor in dopaminergic neurons in the ventral tegmental area. Brain Res 2000, 864:176-185.
    • (2000) Brain Res , vol.864 , pp. 176-185
    • Doherty, M.D.1    Pickel, V.M.2
  • 68
    • 0036192424 scopus 로고    scopus 로고
    • GABA(B) receptor-mediated modulation of the firing pattern of ventral tegmental area dopamine neurons in vivo
    • Erhardt S., Mathe J.M., Cherqui K., Engberg G., Svensson T.H. GABA(B) receptor-mediated modulation of the firing pattern of ventral tegmental area dopamine neurons in vivo. Naunyn Schmiedebergs Arch Pharmacol 2002, 365:173-180.
    • (2002) Naunyn Schmiedebergs Arch Pharmacol , vol.365 , pp. 173-180
    • Erhardt, S.1    Mathe, J.M.2    Cherqui, K.3    Engberg, G.4    Svensson, T.H.5
  • 69
    • 77953181780 scopus 로고    scopus 로고
    • Behavioural evidence for the significance of serotonergic (5-HT) receptors in cocaine addiction
    • Filip M., Alenina N., Bader M., Przegalinski E. Behavioural evidence for the significance of serotonergic (5-HT) receptors in cocaine addiction. Addict Biol 2010, 15:227-249.
    • (2010) Addict Biol , vol.15 , pp. 227-249
    • Filip, M.1    Alenina, N.2    Bader, M.3    Przegalinski, E.4
  • 70
    • 0036708612 scopus 로고    scopus 로고
    • Effects of 5-HT1B receptor ligands microinjected into accumbal shell or core on the cocaine-induced locomotor hyperactivity in rats
    • Przegalinski E., Filip M., Papla I., Czepiel K. Effects of 5-HT1B receptor ligands microinjected into accumbal shell or core on the cocaine-induced locomotor hyperactivity in rats. J Physiol Pharmacol 2002, 53:383-394.
    • (2002) J Physiol Pharmacol , vol.53 , pp. 383-394
    • Przegalinski, E.1    Filip, M.2    Papla, I.3    Czepiel, K.4
  • 71
    • 79952740659 scopus 로고    scopus 로고
    • The locomotor stimulant and discriminative stimulus effects of cocaine: Assessment of the 5-HT1B/1D antagonist GR127935
    • McCreary A.C., Callahan P.M., Cunningham K.A. The locomotor stimulant and discriminative stimulus effects of cocaine: Assessment of the 5-HT1B/1D antagonist GR127935. NIDA Res Monogr 1997, 178:301.
    • (1997) NIDA Res Monogr , vol.178 , pp. 301
    • McCreary, A.C.1    Callahan, P.M.2    Cunningham, K.A.3
  • 72
    • 0033043754 scopus 로고    scopus 로고
    • GR 127935 reduces basal locomotor activity and prevents RU-24969-, but not amphetamine-induced hyperlocomotion, in the Wistar-Kyoto Hyperactive (WKHA) rat
    • Chaouloff F., Courvoisier H., Moisan M.P., Mormede P. GR 127935 reduces basal locomotor activity and prevents RU-24969-, but not amphetamine-induced hyperlocomotion, in the Wistar-Kyoto Hyperactive (WKHA) rat. Psychopharmacology 1999, 141:326-331.
    • (1999) Psychopharmacology , vol.141 , pp. 326-331
    • Chaouloff, F.1    Courvoisier, H.2    Moisan, M.P.3    Mormede, P.4
  • 73
    • 0030439221 scopus 로고    scopus 로고
    • Serotonin-mediated increase in prefrontal cortex dopamine release: pharmacological characterization
    • Iyer R.N., Bradberry C.W. Serotonin-mediated increase in prefrontal cortex dopamine release: pharmacological characterization. J Pharmacol Exp Ther 1996, 277:40-47.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 40-47
    • Iyer, R.N.1    Bradberry, C.W.2
  • 74
    • 0033560989 scopus 로고    scopus 로고
    • RU 24969, a 5-HT1B/1A receptor agonist, potentiates cocaine-induced increases in nucleus accumbens dopamine
    • Parsons L.H., Koob G.F., Weiss F. RU 24969, a 5-HT1B/1A receptor agonist, potentiates cocaine-induced increases in nucleus accumbens dopamine. Synapse 1999, 32:132-135.
    • (1999) Synapse , vol.32 , pp. 132-135
    • Parsons, L.H.1    Koob, G.F.2    Weiss, F.3
  • 75
    • 0033104482 scopus 로고    scopus 로고
    • Regulation of striatal dopamine release through 5-HT1 and 5-HT2 receptors
    • Ng N.K., Lee H.S., Wong P.T. Regulation of striatal dopamine release through 5-HT1 and 5-HT2 receptors. J Neurosci Res 1999, 55:600-607.
    • (1999) J Neurosci Res , vol.55 , pp. 600-607
    • Ng, N.K.1    Lee, H.S.2    Wong, P.T.3
  • 76
    • 1642543877 scopus 로고    scopus 로고
    • Blocking impact of clozapine on cocaine locomotor and sensitizing effects in rats
    • Filip M., Papla I., Nowak E., Przegalinski E. Blocking impact of clozapine on cocaine locomotor and sensitizing effects in rats. Pol J Pharmacol 2003, 55:1125-1130.
    • (2003) Pol J Pharmacol , vol.55 , pp. 1125-1130
    • Filip, M.1    Papla, I.2    Nowak, E.3    Przegalinski, E.4
  • 77
    • 13244258371 scopus 로고    scopus 로고
    • Antipsychotics lack α1A/B adrenoreceptor subtype selectivity in the rat
    • Cahir M., King D.J. Antipsychotics lack α1A/B adrenoreceptor subtype selectivity in the rat. Eur Neuropsychopharmacol 2005, 15:231-234.
    • (2005) Eur Neuropsychopharmacol , vol.15 , pp. 231-234
    • Cahir, M.1    King, D.J.2
  • 78
    • 14944342214 scopus 로고    scopus 로고
    • The role of muscarinic receptor antagonism in antipsychotic-induced hippocampal acetylcholine release
    • Johnson D.E., Nedza F.M., Spracklin D.K., Ward K.M., Schmidt A.W., Iredale P.A., et al. The role of muscarinic receptor antagonism in antipsychotic-induced hippocampal acetylcholine release. Eur J Pharmacol 2005, 506:209-219.
    • (2005) Eur J Pharmacol , vol.506 , pp. 209-219
    • Johnson, D.E.1    Nedza, F.M.2    Spracklin, D.K.3    Ward, K.M.4    Schmidt, A.W.5    Iredale, P.A.6
  • 79
    • 1842510585 scopus 로고    scopus 로고
    • Clozapine modulates midbrain dopamine neuron firing via interaction with the NMDA receptor complex
    • Schweiler L., Engberg G., Erhardt S. Clozapine modulates midbrain dopamine neuron firing via interaction with the NMDA receptor complex. Synapse 2004, 52:114-122.
    • (2004) Synapse , vol.52 , pp. 114-122
    • Schweiler, L.1    Engberg, G.2    Erhardt, S.3
  • 80
    • 0028785179 scopus 로고
    • New insights into the biology of schizophrenia through the mechanism of action of clozapine
    • Brunello N., Masotto C., Steardo L., Markstein R., Racagni G. New insights into the biology of schizophrenia through the mechanism of action of clozapine. Neuropsychopharmacology 1995, 13:177-213.
    • (1995) Neuropsychopharmacology , vol.13 , pp. 177-213
    • Brunello, N.1    Masotto, C.2    Steardo, L.3    Markstein, R.4    Racagni, G.5
  • 81
    • 0037177358 scopus 로고    scopus 로고
    • The antipsychotic aripiprazole is a potent, partial agonist at the human 5-HT1A receptor
    • Jordan S., Koprivica V., Chen R., Tottori K., Kikuchi T., Altar C.A. The antipsychotic aripiprazole is a potent, partial agonist at the human 5-HT1A receptor. Eur J Pharmacol 2002, 441:137-140.
    • (2002) Eur J Pharmacol , vol.441 , pp. 137-140
    • Jordan, S.1    Koprivica, V.2    Chen, R.3    Tottori, K.4    Kikuchi, T.5    Altar, C.A.6
  • 82
    • 0032868798 scopus 로고    scopus 로고
    • The role of serotonin in antipsychotic drug action
    • Meltzer H.Y. The role of serotonin in antipsychotic drug action. Neuropsychopharmacology 1999, 21:106-115.
    • (1999) Neuropsychopharmacology , vol.21 , pp. 106-115
    • Meltzer, H.Y.1
  • 84
    • 22344431960 scopus 로고    scopus 로고
    • Novel antipsychotics activate recombinant human and native rat serotonin 5-HT1A receptors: affinity, efficacy and potential implications for treatment of schizophrenia
    • Newman-Tancredi A., Assie M.B., Leduc N., Ormiere A.M., Danty N., Cosi C. Novel antipsychotics activate recombinant human and native rat serotonin 5-HT1A receptors: affinity, efficacy and potential implications for treatment of schizophrenia. Int J Neuropsychopharmacol 2005, 8:341-356.
    • (2005) Int J Neuropsychopharmacol , vol.8 , pp. 341-356
    • Newman-Tancredi, A.1    Assie, M.B.2    Leduc, N.3    Ormiere, A.M.4    Danty, N.5    Cosi, C.6


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