A novel competitive class of α-glucosidase inhibitors: (E)-1-phenyl-3-(4-styrylphenyl)urea derivatives

ChemBioChem

Volumn 11, Issue 15, 2010, Pages 2125-2131

  Kim, Jun Young ^a   Lee, Ji Won ^a   Kim, Young Soo ^a   Lee, Yuno ^a   Ryu, Young Bae ^c   Kim, Songmi ^a   Ryu, Hyung Won ^a   Curtis Long, Marcus J ^b   Lee, Keun Woo ^a   Lee, Woo Song ^c   Park, Ki Hun ^a  

^a Gyeongsang National University   (South Korea)

^b KRIBB ^*  (United Kingdom)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Alpha glucosidases; Drug design; Inhibitors; Structure activity relationships; Urea stilbene

Indexed keywords

1 (2,4 DIFLUOROPHENYL) 3 [4 (3,4 DIHYDROXYSTYRYL)PHENYL]UREA; 1 (2,4 DIFLUOROPHENYL) 3 [4 (3,5 DIHYDROXYSTYRYL)PHENYL]UREA; 1 (2,4 DIFLUOROPHENYL) 3 [4 (4 HYDROXYSTYRYL)PHENYL]UREA; 1 (4 AMINOPHENYL) 3 [4 (3,4 DIHYDROXYSTYRYL)PHENYL]UREA; 1 (4 CHLOROPHENYL) 3 [4 (3,4 DIHYDROXYSTYRYL)PHENYL]UREA; 1 [4 (3,4 DIHYDROXYSTYRYL)PHENYL) 3 PHENYLUREA; 1 [4 (3,4 DIHYDROXYSTYRYL)PHENYL] 3 (4 FLUOROPHENYL)UREA; 1 [4 (3,4 DIHYDROXYSTYRYL)PHENYL] 3 (4 METHOXYPHENYL)UREA; 1 [4 (3,4 DIHYDROXYSTYRYL)PHENYL] 3 (4 TOLYLUREA); 1 [4 (3,4 DIHYDROXYSTYRYL)PHENYL] 3 (4 TRIFLUOROMETHYLPHENYL)UREA; 1 [4 (3,5 DIHYDROXYSTYRYL)PHENYL] 3 (4 METHOXYPHENYL)UREA; 1 [4 (3,5 DIHYDROXYSTYRYL)PHENYL] 3 PHENYLUREA; 1 [4 (4 HYDROXYSTYRYL)PHENYL] 3 (4 METHOXYPHENYL)UREA; 1 [4 (4 HYDROXYSTYRYL)PHENYL] 3 PHENYLUREA; 1 PHENYL 3 (4 STYRYLPHENYL)UREA DERIVATIVE; ALPHA GALACTOSIDASE; ALPHA GLUCOSIDASE; ALPHA GLUCOSIDASE INHIBITOR; ALPHA MANNOSIDASE; AMYLASE; BETA GLUCOSIDASE; STILBENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; COMPETITIVE INHIBITION; CROSS COUPLING REACTION; DRUG BINDING; DRUG SYNTHESIS; ENZYME ACTIVITY; PRIORITY JOURNAL; STEREOCHEMISTRY;

ALPHA-GLUCOSIDASES; BINDING, COMPETITIVE; ENZYME INHIBITORS; KINETICS; PHENYLUREA COMPOUNDS; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP; UREA;

EID: 79751486202     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201000376     Document Type: Article

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